Search Patents
  • Auto-injector
    Patent number: 10500337
    Abstract: An autoinjector having a body (1) receiving a reservoir (S) containing fluid and including a piston (P), such as a pre-filled syringe; a piston rod (5) that co-operates with the piston (P), the piston rod (5) being movable by an injection spring (8) between a primed position and an injection position in which the piston rod (5) has moved the piston (P) of the reservoir (S) so as to inject the fluid into an injection site; and an indicator device for indicating to the user that the autoinjector may be removed from said injection site. The autoinjector also includes a retarding system to delay the end of actuating the indicator device relative to the end of injection, the indicator device generating a noise while being actuated, the noise being generated until the end of actuating the indicator device.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: December 10, 2019
    Assignee: APTAR FRANCE SAS
    Inventors: David Fabien, Thomas Gomez, Anthony Saussaye, Philippe Pinheiro
  • Compositions of R(+) and S(?) pramipexole and methods of using the same
    Patent number: 8017598
    Abstract: Compositions of predetermined amounts of R(+) pramipexole and S(?) pramipexole and methods of using the same, including for the treatment and prevention of Parkinson's disease, are provided.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: September 13, 2011
    Assignee: Knopp Neurosciences, Inc.
    Inventors: Michael E. Bozik, Thomas Petzinger, Jr., Valentin Gribkoff
  • Use of aluminium chloride as a resveratrol synthesis elicitor
    Patent number: 6080701
    Abstract: The use of aluminium chloride as a resveratrol synthesis elicitor in crop plants and edible products thereof, particularly in the field of vine and grape growing as well as in the production of grape juice and wine, is disclosed.
    Type: Grant
    Filed: May 12, 1998
    Date of Patent: June 27, 2000
    Assignee: Laboratoires Goemar S.A.
    Inventors: Philippe Jeandet, Roger Bessis, Marielle Adrian, Jean-Claude Yvin, Jean-Marie Joubert
  • Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
    Patent number: 5582835
    Abstract: Methods for preventing and treating corneal haze resulting from exposure of the eye to laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators to the eye. Compositions for use in preventing and treating the corneal haze are also disclosed.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: December 10, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: Stella M. Robertson, Herman M. Kunkle, Jr.
  • Cosmetic use of copolymers with a rigid hydrophilic backbone grafted by flexible hydrophobic macromonomers, and compositions therefor
    Patent number: 6403106
    Abstract: The subject-matter of the present invention is the use, in and for the preparation of cosmetic or dermatological compositions, of a grafted copolymer, the skeleton (S) of which is composed of a hydrophilic copolymer, with a glass transition temperature Tg greater than 25° C., obtained by radical polymerization or by polycondensation, comprising, on the chain of the skeleton (S), at least one graft composed of a hydrophobic macromonomer (M) with a glass transition temperature T'g of less than 25° C., as well as the cosmetic or dermatological compositions employed.
    Type: Grant
    Filed: November 18, 1998
    Date of Patent: June 11, 2002
    Assignee: L'Oreal, S.A.
    Inventors: Henri Sebag, Nathalie Mougin, Bertrand Lion, Jean Mondet
  • Secretases related to Alzheimer's dementia
    Patent number: 6313268
    Abstract: This invention is directed to a novel &bgr;-secretase that produces the A&bgr; peptide found in Alzheimer's Disease. One &bgr;-secretase is a protein having a molecular weight of about 61, 81 or 88 kDa that cleaves an amyloid precursor protein (APP) substrate. Another is a protease complex having a molecular between about 180 and 200 kDa, which, in one embodiment, contains the 61, 81, and 88 kDa proteins and, in another embodiment, contains proteins having a molecular weight of about 66, 60, 33 and 29 kDa. Another &bgr;-secretase has a molecular weight between about 50 and 90 kDA. The invention is also directed to methods of selecting agents that inhibit A&bgr; peptide production and treating Alzheimer's disease in patients.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: November 6, 2001
    Inventor: Vivian Y. H. Hook
  • Method and apparatus for designing photomasks
    Patent number: 5541025
    Abstract: Method and apparatus for designing the photomask in the course of designing the Levenson-type phase shift mask, capable of automatically arranging the shifter, of not causing a contradictory spot in a circuit designing stage and of automatically forming a final layout achieving maximum integrity. The method includes the steps of: forming symbolic layout data in which a distance between adjacent clear areas is set to an arbitrary value; determining regions having a mutual phase difference 0.degree. or 180.degree. of light transmitting through adjacent patterns corresponding to the clear areas in the symbolic layout data; executing compaction of the symbolic layout in a manner that design rule S1 is adopted to the clear areas neighboring with the phase difference of 180.degree. and design rule S2 is adopted to the clear areas neighboring with the phase difference of 0.degree.; and forming mask layout data such that S1 is less than S2.
    Type: Grant
    Filed: December 28, 1994
    Date of Patent: July 30, 1996
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Kazuko Oi, Kiyomi Koyama
  • Novel Pyrrole Inhibitors of S-Nitrosoglutathione Reductase as Therapeutic Agents
    Publication number: 20130253024
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Application
    Filed: May 24, 2013
    Publication date: September 26, 2013
    Applicant: N30 Pharmaceuticals, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Modular multisource beam shaping system
    Patent number: 10551038
    Abstract: A beam shaper module and an automated luminaire are provided. The beam shaper can be installed on or removed from an automated luminaire that produces a plurality of beams of light. The beam shaper module includes a housing, a beam shaper, one or more motors, and a control circuit. The housing detachably couples to a light emitting face of a head of the luminaire. The beam shaper includes an array of ribbed lenses, each lens extending across the beam shaper and receiving light from fewer than all of the light beams. The motor(s) rotate the beam shaper about an axis of rotation coincident with an optical axis of the luminaire. The control circuit receives power and control signals from the luminaire and, in response to the control signals, controls rotation of the beam shaper using the motor(s).
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: February 4, 2020
    Assignee: Robe Lighting s.r.o.
    Inventors: Pavel Jurik, Josef Valchar
  • Adaptable input device support
    Patent number: 6704003
    Abstract: An input device includes a replaceable support for the user's hand which can be selected to provide improved comfort and support for the hand for operating the input device. The replaceable support allows the user to select a shell to fit his or her hand and to provide the desired functionality. In specific embodiments, the adaptable computer input device comprises a core module including an input element for a user to provide input to a computer. An outer shell is selected from a group of different outer shells which are detachably connectable to the core module to support a user's hand for manipulating the input element of the core module to provide input to the computer. The core module automatically detects operational information of the outer shell upon coupling of the outer shell with the core module and adapts operation of the core module to the outer shell connected thereto in response to detected operational information of the outer shell.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: March 9, 2004
    Assignee: Logitech Europe S.A.
    Inventors: Guy Tiphane, Samantha Moy
  • Low application temperature hot melt adhesive composition and a method including the same
    Patent number: 10584267
    Abstract: The invention features a hot melt adhesive composition that can be applied at temperatures as low as 107° C., while maintaining excellent bonding under stress and a very fast setting time.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: March 10, 2020
    Assignee: H.B.Fuller Company
    Inventors: Richard B. Sergeant, Thomas F. Kauffman
  • Avalanche photodiode for photon counting applications and method thereof
    Patent number: 6797581
    Abstract: A method for manufacturing an improved APD structure and an improved manner of operating APD's particularly beneficial for a single photon detection applications are provided. An APD is provided having an absorption region, a control region, and a multiplication region, wherein the multiplication region has a k value of approximately 1. In one example the multiplication region comprises a doped InP layer. The field control layer is designed so as to produce a reduction of electric field that is equal to the multiplication region's breakdown electric field, plus or minus 5V/&mgr;m. The method comprises applying a potential across the APD so as to induce an electric field across the multiplication region that exceeds the breakdown field; while having the control region shield the absorption region to prevent excessive noise.
    Type: Grant
    Filed: November 24, 2003
    Date of Patent: September 28, 2004
    Assignee: Credence Systems Corporation
    Inventor: James S. Vickers
  • TFE copolymers
    Patent number: 7037991
    Abstract: Copolymers formed by TFE and FMVE containing FMVE in percent by moles from 2.5% to 8%; the % TFE moles being the complement to 100% of the FMVE moles.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: May 2, 2006
    Assignee: Solvay Solexis S.p.A.
    Inventors: Pasqua Colaianna, Giulio Brinati, Vincenzo Arcella
  • Electronic timepiece
    Patent number: 3992869
    Abstract: An electronic timepiece includes an oscillating circuit for operating the timepiece. The oscillating circuit includes a capacitor having a value which determines the frequency of the oscillator and therefore the timepiece timing. The capacitor is removable and replaceable for repairing or adjusting the timepiece timing operation.
    Type: Grant
    Filed: November 25, 1974
    Date of Patent: November 23, 1976
    Assignee: Ebauches S.A.
    Inventor: Rene Meister
  • Method for using hydratase or a hydratase-amidase fusion for stereospecifically bioconverting certain racemic nitriles to the corresponding enatiomeric R--or S-amide or s-carboxylic acid
    Patent number: 5888785
    Abstract: The present invention provides a nitrile hydratase nucleic acid fragment isolated from Pseudomonas putida which encodes a nitrile hydratase activity capable of catalyzing the hydrolysis of certain racemic nitrites to the corresponding R- or S-amides. Also provided are transformed microorganisms capable of the active expression of said nitrile hydratase activity. Additionally, the invention provides a transformant harboring the nitrile hydratase gene in conjunction with an amidase gene, both of which may be co-expressed producing active nitrile hydratase and amidase enzymes respectively. Methods for the production of such enantiomeric materials are also provided.
    Type: Grant
    Filed: June 24, 1998
    Date of Patent: March 30, 1999
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Robert Donald Fallon, Mark James Nelson, Mark Scott Payne
  • Method for estimating the state of health of an electrochemical cell for storing electrical energy
    Patent number: 11143709
    Abstract: A method for estimating a state of health of an electrochemical cell for storing electrical energy includes applying at least one current strength peak to the cell, the current peak passing through the cell, measuring a variation, as a function of a time t elapsed after the application of the current peak, of voltage U at the terminals of the cell, and calculating at least one coefficient ?I1 and at least one coefficient U0,I1 such that the function ?{square root over (t)}??I1×?{square root over (t)}+U0,I1 is a linear approximation of the variation of the voltage U as a function of ?{square root over (t)} for ?{square root over (t)}?C, where C>0. The method is used in electrical or hybrid vehicles.
    Type: Grant
    Filed: May 26, 2014
    Date of Patent: October 12, 2021
    Assignee: RENAULT s.a.s.
    Inventors: Bruno Delobel, Antoine Saint-Marcoux
  • Choke for enhanced gas and oil well production
    Patent number: 5445225
    Abstract: The claimed apparatus is a bottom hole choke device for regulating the flow within gas and oil producing wells. The apparatus includes a screen for preventing sand from entering the production string, a flow-restricting choke, and a check valve for preventing back flow into the well.
    Type: Grant
    Filed: September 2, 1994
    Date of Patent: August 29, 1995
    Inventor: Merl D. Wiggins, Sr.
  • Method, apparatus, and system for refueling hydrogen vehicles
    Patent number: 10240721
    Abstract: A dispenser apparatus that includes a first cascade stage having a first connector configured to connect to and disconnect from a first gas storage vessel, and a first conduit connected to the first connector and having a first valve and a first pressure measuring device, and a second cascade stage having a second connector configured to connect to and disconnect from a second gas storage vessel, and a second conduit connected to the second connector and having a second valve and a second pressure measuring device. A common flow path is fluidly connected to the conduits, and has a dispensing nozzle to connect to a vehicle during refueling. A controller is provided to control the first and/or second valve(s) to perform refueling using gas stored in at least one of the first and second gas storage vessels based on pressure measurements of the first and/or second pressure measuring device(s).
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: March 26, 2019
    Assignee: ONEH2, INC.
    Inventors: Paul A. Dawson, Franklin D. Lomax, Rafael S. Lemos, David Houng
  • S-adenosyl-L-methionine synthetase promoter and its use in expression of transgenic genes in plants
    Publication number: 20030226166
    Abstract: A constitutive plant S-adenosyl-L-methionine synthetase (SAMS) promoter and subfragments thereof and their use in promoting the expression of one or more heterologous nucleic acid fragments in plants are described.
    Type: Application
    Filed: May 7, 2003
    Publication date: December 4, 2003
    Inventors: Saverio Carl Falco, Zhongsen Li
  • System and method for transport block size design for multiple-input, multiple-output (MIMO) in a wireless communications system
    Patent number: RE46810
    Abstract: In one embodiment, a method for transmitting information includes processing a downlink transport channel to generate a transport block (TB) having a TB size. The TB size is selected by selecting a modulation and coding scheme index (ITBS) and a physical resource block index (NPRB). The TB size for the selected ITBS and NPRB is selected so that an effective code rate at an user equipment (UE) does not exceed a specified threshold. The effective code rate is defined as a number of downlink (DL) information bits including TB cyclic redundancy check (CRC) bits and code block CRC bits divided by a number of physical channel bits on Physical Downlink Shared Channel (PDSCH). The transport block is mapped to multiple spatial layers. The number of spatial layers N is greater than or equal to three. The multiple spatial layers are transmitted to the UE.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: April 24, 2018
    Assignee: FUTUREWEI TECHNOLOGIES, INC.
    Inventors: Ying Jin, Yufei Blankenship
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