Search Patents
  • TOPICAL COMPOSITION COMPRISING ANTIMICROBIAL LIPID
    Publication number: 20200360260
    Abstract: Disclosed is a topical composition comprising an antimicrobial lipid found in the sebum or stratum corneum of human beings, other than saturated C8 to 18 fatty acids, wherein said composition further comprises a biphenol obtainable from Magnolia spp.
    Type: Application
    Filed: November 15, 2018
    Publication date: November 19, 2020
    Applicant: Conopco, Inc., d/b/a UNILEVER
    Inventors: Chung-Ching CHU, Mingming PU, Yining XU
  • Topical Sphingosine-1-Phosphate Receptor Agonist Formulations and Methods of Using the Same
    Publication number: 20150104497
    Abstract: Topical sphingosine-1-phosphate receptor agonist active agent formulations are provided. Aspects of the transdermal formulations include an amount of a sphingosine-1-phosphate receptor agonist active agent in combination with a topical delivery vehicle, e.g., a topical patch that includes an adhesive layer and a backing layer. Also provided are methods of topically delivering a therapeutically effective amount of a sphingosine-1-phosphate receptor agonist active agent to a subject, e.g., to treat a subject for a disease condition, such as an immune system disorder like multiple sclerosis, a hyperproliferative dermatological disorder, e.g., psoriasis, acne, etc. Packaged topical formulations, kits including such formulations, and methods of making such formulations are also provided.
    Type: Application
    Filed: August 29, 2014
    Publication date: April 16, 2015
    Inventors: Adchara Pongpeerapat, Bret Berner, Kensuke Murata
  • Pharmaceutical composition for topical administration
    Publication number: 20040208906
    Abstract: A pharmaceutical composition for topical administration, which resides at a topical site of application for a long period and can control the release rate of an active agent, is provided. The present invention is a pharmaceutical composition for topical administration comprising an active ingredient, a water insoluble polymer, and a solvent capable dissolving the water insoluble polymer and compatible with water, and optionally containing other additive.
    Type: Application
    Filed: January 5, 2004
    Publication date: October 21, 2004
    Applicant: Daiichi Suntory Pharma Co., Ltd.
    Inventors: Mitsutoshi Tatara, Toshihito Shimizu, Ryoichi Fukumoto, Masaaki Nomura
  • Visualization and analysis of a topical element of a complex system
    Patent number: 9489597
    Abstract: An apparatus is provided for implementation of a system for visualization and analysis of a complex system such as an aircraft composed of a plurality of elements. The apparatus may be caused to receive and process data for physical instance(s) of the complex system to identify a topical element. The apparatus may be caused to receive a digital 3D model of the complex system, generate a visual presentation of at least a portion of the digital 3D model, with the visual presentation depicting the topical element and one or more other elements of the plurality of elements. And the apparatus may be caused to apply a visual effect to the topical element depicted by the visual presentation to distinguish the topical element from the other element(s) depicted by the visual presentation.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: November 8, 2016
    Assignee: The Boeing Company
    Inventors: Joseph F. Floyd, Brent L. Hadley, Patrick J. Eames, Darren B. Macer
  • Topical Formulations Including Lipid Microcapsule Delivery Vehicles and Their Uses
    Publication number: 20140348910
    Abstract: The present invention relates to topical formulations that include lipid microcapsules formed from tocopherol, tocotrienol, or mixtures thereof; a stabilizer/surfactant component; and an aqueous component. The lipid microcapsules may be formed without the use of steroids, preservatives, initiators and/or oils. The topical formulations are capable of delivering transdermal active agent(s) such as vitamin D through the skin and into the bloodstream without the use of skin penetration enhancers. In certain embodiments, the topical formulations also able to deliver topical active agent(s) such as sun-protecting agents to the surface of the skin where they remain, while simultaneously delivering the transdermal active agent(s) through the skin and into the bloodstream.
    Type: Application
    Filed: June 29, 2012
    Publication date: November 27, 2014
    Applicant: AVIDAS PHARMACEUTICALS LLC
    Inventor: David Craig Wright
  • STABILIZED AND SOLUBILIZED DRUG FORMULATION FOR TOPICAL APPLICATION AND TRANSDERMAL EFFICACY FOR COSMETIC IMPROVEMENT AND METHODS OF FORMULATION
    Publication number: 20150157728
    Abstract: The invention relates to a novel stabilized and solubilized topical formulation for cosmetic improvements and methods of making the same comprising multiplexed molecular penetration enhancers and essential and semi-essential amino acid protein binders for the topical application and transdermal delivery of one or more active ingredients and/or pharmaceutical agents. The invention further relates to the use of the topical formulation in connection with the providing of cosmetic improvements in individuals.
    Type: Application
    Filed: December 10, 2013
    Publication date: June 11, 2015
    Inventor: PANKAJ MODI
  • TOPICAL FORMULATIONS OF 5-ALPHA-REDUCTASE INHIBITORS AND USES THEREOF
    Publication number: 20200147071
    Abstract: Disclosed herein are topical compositions of 5-? reductase inhibitors, such as dutasteride or finasteride, or a pharmaceutically acceptable salt, ester, or derivative thereof and the use of the compositions for the treatment of hair loss secondary to endocrine therapy in patients with breast cancer (Endocrine Therapy-Induced Alopecia or ETIA), androgenetic alopecia (AGA), alopecia areata, and hirsutism. The topical composition is advantageous over the existing oral compositions of 5-? reductase inhibitors because the topical composition is safer and more effective. The topical formulation may allow for a slow release of the active ingredient dutasteride, better penetration at the therapeutically effective amount of dutasteride with an improved safety profile because it does not need to travel through the bloodstream to be efficacious, thereby minimizing the risk of systemic side effects.
    Type: Application
    Filed: November 7, 2019
    Publication date: May 14, 2020
    Inventor: Vinay K. Jindal
  • Topical resource recommendations for a displayed resource
    Patent number: 10467300
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for providing contextual information to a user. In one aspect, a method includes receiving, from a user device, a query-independent request for contextual information relevant to an active resource displayed in an application environment on the user device, identifying entities from content in the resource, generating queries for topical information based on the entities identified from the content, identifying topical resources that are responsive to the queries for topical information, and providing, to the user device, a user interface element for display with the active resource, wherein the user interface element includes contextual information regarding the identified topical resources.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: November 5, 2019
    Assignee: Google LLC
    Inventors: Michal Jastrzebski, Ibrahim Badr, Gokhan H. Bakir, Aneto Okonkwo, Marcin M. Nowak-Przygodzki
  • TOPICAL COMPOSITION FOR CONTROL OF DEMODEX
    Publication number: 20250057784
    Abstract: A topical composition for treating overgrowth of Demodex mites. The topical composition preferably includes one or more active ingredients, optionally encapsulated in lipids. In example embodiments, the topical composition comprises a first active ingredient between either tea tree oil or terpinen-4-ol, and additional active ingredients including sea whip extract, bisabolol, and Camellia sinensis leaf extract.
    Type: Application
    Filed: November 6, 2024
    Publication date: February 20, 2025
    Inventors: Mark H. Bruder, Rodney L. Dobson, Deborah L. Duffey, Jeffrey Reynolds
  • Wearable container assembly for holding a topical substance
    Patent number: 9949551
    Abstract: A wearable container assembly for holding a topical substance configured to be applied to a portion of a body of a user is disclosed herein. The wearable container assembly includes a base portion having a top surface and a bottom surface, the base portion including one or more decorative elements attached to the top surface thereof; a fastener member attached to the bottom surface of the base portion, the fastener member configured to removably attach the wearable container assembly to hair of a user, a limb of a user, or an article of clothing worn by the user; and a container subassembly for holding a topical substance that is configured to be applied to a portion of a body of the user, the container subassembly removably coupled to the base portion by attachment means. A wearable topical substance container assembly comprising a topical substance is also disclosed herein.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: April 24, 2018
    Inventors: Alaina Taylor Boles, Kimberly Ann Boles, Joseph Douglas Boles
  • TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20160074316
    Abstract: Topical cosmetic compositions are provided that can comprise a Phyllanthus extract, a Bellis extract, and a licorice (Glycyrrhiza) extract. These compositions are used for topical cosmetic applications, particularly to lighten skin. Methods for lightening skin are also provided and can comprise topically administering a therapeutically effective amount of a topical cosmetic composition comprising a Phyllanthus extract, a Bellis extract, and a licorice extract, to skin of a subject in need thereof.
    Type: Application
    Filed: November 24, 2015
    Publication date: March 17, 2016
    Inventors: Joao Paulo CAETANO, Monica De Oliveira
  • TOPICAL COMPOSITION FOR TREATMENT AND/OR PROPHILAXIS OF MASTITIS AND/OR EDEMA
    Publication number: 20190046550
    Abstract: The present invention relates to a topical composition which is mixture of natural ingredients of plant and animal origin, to the process of its preparation, to its use for treatment and/or prophylaxis of mastitis and/or edema in female mammals, more particularly to its use for treatment and/or prophylaxis of mastitis and/or udder edema in dairy animals. The topical composition according to the invention is mixture of natural ingredients of plant and animal origin, wherein the topical composition comprises: sugar, carboxylic acid solution, egg white and vehicle.
    Type: Application
    Filed: February 3, 2017
    Publication date: February 14, 2019
    Inventors: Dragan GAVRANOVIC, Dragana JOVIC
  • METHOD FOR EXTRACTING A COMPACT REPRESENTATION OF THE TOPICAL CONTENT OF AN ELECTRONIC TEXT
    Publication number: 20090292698
    Abstract: An electronic document is parsed to remove irrelevant text and to identify the significant elements of the retained text. The elements are assigned scores representing their significance to the topical content of the document. A matrix of element-pairs is constructed such that the matrix nodes represent the result of one or more functions of the scores and other attributes of the paired elements. The resulting matrix is a compact representation of topical content that affords great precision in information retrieval applications that depend on measurements of the relatedness of topical content.
    Type: Application
    Filed: August 5, 2009
    Publication date: November 26, 2009
    Inventors: Martin Remy, Steven Nieker
  • Moisturizing topical preparation
    Patent number: 11278485
    Abstract: The present invention provides a novel topical moisturizing preparation containing as an active ingredient at least one selected from pentosan polysulfate; pharmaceutically acceptable salts of pentosan polysulfate; and pharmaceutically acceptable solvates thereof. The topical moisturizing preparation of the present invention, which contains a substance free of animal-derived components as an active ingredient, can be produced as a topical moisturizing preparation free of animal-derived components, as needed.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: March 22, 2022
    Assignee: OJI HOLDINGS CORPORATION
    Inventors: Kotaro Ishikawa, Takuro Kashiwamura, Takuya Kato, Toru Koga, Suguru Ishikawa
  • TOPICAL NAIL FORMULATION
    Publication number: 20090215888
    Abstract: The present invention relates to a topical nail formulation comprising at least one active agent (e.g., tolnaftate) and at least one nail penetration enhancer selected from the group consisting of a fatty acid, an azone derivative, and mixtures thereof. The invention also relates to the use of said topical nail formulation for the treatment of nail disorders such as onychomycosis. The invention further provides a method of enhancing the nail flux of an active agent by using a topical nail formulation containing the said penetration enhancer.
    Type: Application
    Filed: March 1, 2007
    Publication date: August 27, 2009
    Inventors: Singh Jagat, Dan McKay
  • Topical Cosmetic Skin Lightening Compositions and Methods of use Thereof
    Publication number: 20110182835
    Abstract: Topical cosmetic compositions are provided that can comprise a Phyllanthus extract, a Bellis extract, and a licorice (Glycyrrhiza) extract. These compositions are used for topical cosmetic applications, particularly to lighten skin. Methods for lightening skin are also provided and can comprise topically administering a therapeutically effective amount of a topical cosmetic composition comprising a Phyllanthus extract, a Bellis extract, and a licorice extract, to skin of a subject in need thereof.
    Type: Application
    Filed: November 19, 2008
    Publication date: July 28, 2011
    Inventors: Joao Paulo Caetano, Monica Alves Mariani De Oliveira
  • TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20160074315
    Abstract: Topical cosmetic compositions are provided that can comprise a Phyllanthus extract, a Bellis extract, and a licorice (Glycyrrhiza) extract. These compositions are used for topical cosmetic applications, particularly to lighten skin. Methods for lightening skin are also provided and can comprise topically administering a therapeutically effective amount of a topical cosmetic composition comprising a Phyllanthus extract, a Bellis extract, and a licorice extract, to skin of a subject in need thereof.
    Type: Application
    Filed: November 24, 2015
    Publication date: March 17, 2016
    Inventors: Joao Paul CAETANO, Monica Alves Mariani De OLIVEIRA
  • Deep topical systemic nitric oxide therapy apparatus and method
    Patent number: 10828249
    Abstract: A topical mixture that produces nitric oxide and a method for using the topical mixture to increase the vasodilation of a bloodstream via transdermal absorption of the nitric oxide. The nitric oxide can then affect subcutaneous tissues. The systemic vasodilation of a mammal may be increased via a topical application of an appropriate nitric oxide producing substance.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: November 10, 2020
    Assignee: SYK TECHNOLOGIES, LLC
    Inventors: Christian S. Minton, Stephen D. Minton, J. W. Randolph Miller
  • Topical sphingosine-1-phosphate receptor agonist formulations and methods of using the same
    Patent number: 10022340
    Abstract: Topical sphingosine-1-phosphate receptor agonist active agent formulations are provided. Aspects of the transdermal formulations include an amount of a sphingosine-1-phosphate receptor agonist active agent in combination with a topical delivery vehicle, e.g., a topical patch that includes an adhesive layer and a backing layer. Also provided are methods of topically delivering a therapeutically effective amount of a sphingosine-1-phosphate receptor agonist active agent to a subject, e.g., to treat a subject for a disease condition, such as an immune system disorder like multiple sclerosis, a hyperproliferative dermatological disorder, e.g., psoriasis, acne, etc. Packaged topical formulations, kits including such formulations, and methods of making such formulations are also provided.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: July 17, 2018
    Assignee: Teikoku Pharma USA, Inc.
    Inventors: Adchara Pongpeerapat, Bret Berner, Kensuke Murata
  • Topical pharmaceutical compositions for treating skin conditions
    Patent number: 11324710
    Abstract: Topical pharmaceutical compositions for treating a skin condition or disorder are provided. The topical pharmaceutical compositions can be formulated as lotions containing a therapeutically effective amount of an active agent, such as tretinoin, a viscosity increasing agent, and advantageously small amounts of both a polymeric emulsifier and an oil component. The topical compositions of the present invention are tolerated exceptionally well by subjects to whom the compositions are administered.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: May 10, 2022
    Assignee: BAUSCH HEALTH IRELAND LIMITED
    Inventors: Varsha Bhatt, Radhakrishnan Pillai
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