Abstract: The present invention relates to the use of GPR119 receptor agonists for treating or preventing a condition characterized by low bone mass, such as osteoporosis, and for increasing bone mass in an individual. The present invention further relates to the use of a GPR119 receptor agonist in combination with a dipeptidyl peptidase IV (DPP-IV) inhibitor for treating or preventing a condition characterized by low bone mass, such as osteoporosis, and for increasing bone mass in an individual. A GPR119 receptor agonist and the combination of a GPR119 receptor agonist and a DPP-IV inhibitor promote bone formation in an individual.

Abstract: A method, an apparatus, a computer readable storage medium configured with instructions for carrying out a method, and logic encoded in one or more computer-readable tangible medium to carry out actions. The method is to decode audio data that includes N.n channels to M.m decoded audio channels, including unpacking metadata and unpacking and decoding frequency domain exponent and mantissa data; determining transform coefficients from the unpacked and decoded frequency domain exponent and mantissa data; inverse transforming the frequency domain data; and in the case M<N, downmixing according to downmixing data, the downmixing carried out efficiently.

Abstract: Systems and methods for determining the identity of entities who meet trust requirements of a privilege grantor include an identity and trust management system including at least one computing device in communication with at least one entity, at least one privilege grantor, and at least one authoritative source. At least one rule is received from the at least one privilege grantor that must be satisfied for the at least one privilege grantor to trust an entity. A database is established of at least one entity with information about the at least one entity. The at least one authoritative source is queried to determine whether at least a portion of the information about the at least one entity is correct. A response is received from the at least one authoritative source as to whether or not the portion of information is correct. The database stores a result of the query without storing data underlying the result.

Abstract: The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.

Abstract: The invention provides a human capital development framework which allows organizations to assess the business impact of human capital initiatives and guide their implementation. The invention further provides a four-tier tool for arriving at an assessment of an organization's human capital practices. The first tier includes a measurement of business results, the second tier involves key performance drivers which contribute to business results, the third tier involves human capital capabilities and the fourth tier involves human capital processes. Surveys are provided to collect data for each tier and a detailed report is generated based upon survey results.

Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, p, q, Ar, R1 and R2 are as defined herein. Also provided are methods for preparing, compositions comprising, and methods for using compounds of formula I.

Abstract: A method and apparatus for providing variable resistance in connection with exercise equipment uses vertically oriented weight plates that rare in a side-by-side arrangement and are selected by selectors in a selector assembly. A set of actuators are controlled by a computer processor and force the selectors into positions that engage and disengage with a corresponding set of weights. The computer is connected to a user interface that accepts input from a user and instructs the computer to adjust the amount of weight using the actuators and the corresponding selectors. The computer is also in communication with sensors that indicate whether the weights have been lifted successfully and automatically select a lower weight when the weights are not lifted successfully.

Abstract: A method, system and computer program are provided for problem determination in an enterprise computer system in a distributed environment. Information is obtained regarding the enterprise applications, and high-level information is presented to a user, with one or more prompts are provided to the user for more detailed information. In response to a request from a user for more detailed information about the application, more detailed information is provided to the user. Several levels of more detailed information about applications, including information as to individual threads, is available. The problem determination also includes receiving instructions from an administrator to establish an account for a user, associating one or more servers with the account, and providing access to the corresponding user only to the associated servers. Searches may be conducted for strings and requests, and identified strings and requests may be sorted by a variety of criteria.

Abstract: An external defibrillator is customized for at least one person, i.e., an anticipated patient, through creation of a profile for the anticipated patient that allows the defibrillator and users of the defibrillator to provide customized treatment to the patient. The profile may include treatment parameters for the anticipated patient, such as defibrillation therapy parameters selected for the patient. The profile may also include a baseline recording of a physiological parameter of the patient, and medical history and personal information regarding the patient. In some embodiments, the external defibrillator stores a profile for each of one or more anticipated patients within a memory. In other embodiments, a profile for an anticipated patient is stored within a medium associated with that anticipated patient. The medium may, for example, be a removable medium for external defibrillators.

Abstract: An external defibrillator is customized for at least one person, i.e., an anticipated patient, through creation of a profile for the anticipated patient that allows the defibrillator and users of the defibrillator to provide customized treatment to the patient. The profile may include treatment parameters for the anticipated patient, such as defibrillation therapy parameters selected for the patient. The profile may also include a baseline recording of a physiological parameter of the patient, and medical history and personal information regarding the patient. In some embodiments, the external defibrillator stores a profile for each of one or more anticipated patients within a memory. In other embodiments, a profile for an anticipated patient is stored within a medium associated with that anticipated patient. The medium may, for example, be a removable medium for external defibrillators.

Abstract: A car seat includes a vertically adjustable head rest and harness support apparatus that will properly locate the position of the harness relative to the child in response to the positioning of the head rest. The head rest is movable along a curved track to provide horizontal clearance with respect to the vehicle head rest when in a fully raised position. The harness belt is trapped in a length adjustment lock and follows a path that extends around a fixed guide bar at the top of the car seat frame then downwardly through a guide member that directs the belt through an opening in the seat back for engagement with the child. The guide member is supported on a harness control tube that engages a rack device to fix the position of the harness control tube when the position of the head rest is selected.

Abstract: Systems and methods for orthogonal frequency division multiplexing are provided. In one embodiment, a multi-carrier modem comprises: a receiver configured to receive a waveform comprising a plurality of spectrally overlapping carrier signals from at least two of a plurality of remote units, wherein the plurality of spectrally overlapping carrier signals are modulated using an inverse Fourier transform algorithm; a transmitter; a processor coupled to the transmitter, wherein the processor outputs data for transmission to the transmitter, wherein the processor applies an inverse Fourier transform algorithm to the data provided to the transmitter; a controller programed to instruct the transmitter to transmit a predetermined identifier on at least one of the spectrally overlapping carrier signals, the predetermined identifier identifying to a first remote unit a range of the plurality of spectrally overlapping carrier signals for the first remote unit to receive control information.

Abstract: An external defibrillator is customized for at least one person, i.e., an anticipated patient, through creation of a profile for the anticipated patient that allows the defibrillator and users of the defibrillator to provide customized treatment to the patient. The profile may include treatment parameters for the anticipated patient, such as defibrillation therapy parameters selected for the patient. The profile may also include a baseline recording of a physiological parameter of the patient, and medical history and personal information regarding the patient. In some embodiments, the external defibrillator stores a profile for each of one or more anticipated patients within a memory. In other embodiments, a profile for an anticipated patient is stored within a medium associated with that anticipated patient. The medium may, for example, be a removable medium for external defibrillators.

Abstract: One embodiment of the present invention provides a system that facilitates interaction between two entities located away from each other. The system includes a virtual reality system, an augmented reality system, and an object-state-maintaining mechanism. During operation, the virtual reality system displays an object associated with a real-world object. The augmented reality system displays the object based on a change to the state of the object. The object-state-maintaining mechanism determines the state of the object and communicates a state change to the virtual reality system, the augmented reality system, or both. A respective state change of the object can be based on one or more of: a state change of the real-world object; a user input to the virtual reality system or the augmented reality system; and an analysis of an image of the real-world object.

Abstract: Compounds of the formula: or pharmaceutically acceptable salts thereof, wherein m, n, Ar, R1, R2, Ra and Rb are defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the compounds.

Abstract: An implantable medical device comprises an anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.

Abstract: Determination of non-linearity of a positioning scanner of a measurement tool is disclosed. In one embodiment, a method may include providing a probe of a measurement tool coupled to a positioning scanner; scanning a surface of a first sample with the surface at a first angle relative to the probe to attain a first profile; scanning the surface of the first sample with the surface at a second angle relative to the probe that is different than the first angle to attain a second profile; repeating the scannings to attain a plurality of first profiles and a plurality of second profiles; and determining a non-linearity of the positioning scanner using the different scanning angles to cancel out measurements corresponding to imperfections due to the surface of the sample. The non-linearity may be used to calibrate the positioning scanner.

Abstract: A dialysis fluid system includes an instrument including a pump actuator and a fluid heater, and a dialysis fluid cassette. The dialysis fluid cassette includes a rigid portion defining a pumping section for operation with the pump actuator and a heating section for operation with the fluid heater. The heating section includes a dialysis fluid inlet, a dialysis fluid outlet, and a dialysis fluid heating area located between the fluid inlet and the fluid outlet, the heating section further includes an air separation chamber for collecting air separated from the dialysis fluid.

Abstract: The present invention provides nucleotide sequences encoding an insecticidal protein exhibiting lepidopteran inhibitory activity, as well as a novel insecticidal protein referred to herein as a Cry1A.105 insecticide, transgenic plants expressing the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.

Abstract: The present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof and a process for making thereof. The compounds have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention also provides intermediate compounds useful in the process, as well as final products produced by the process, and salts or prodrugs thereof. The invention further provides a method of inhibiting kinases and treating disease states in a mammal by inhibiting the phosphorylation of kinases comprising administering an effective amount of a compound according to the invention to a patient in need thereof.