Abstract: The invention provides human polymorphisms that are associated with Parkinson's disease (PD). Also disclosed are compositions and methods for use in diagnostics, prognostics, prevention, treatment and/or study of PD.
Abstract: Inferring a characteristic of an individual is disclosed. An indication that a first user and a second user have at least one shared chromosomal segment is received. Information about the second user is obtained. A characteristic of the first user is inferred based at least in part on the information about the second user.
Type:
Grant
Filed:
October 22, 2020
Date of Patent:
October 11, 2022
Assignee:
23andMe, Inc.
Inventors:
John Michael Macpherson, Brian Thomas Naughton, Joanna Louise Mountain
Abstract: Inferring a characteristic of an individual is disclosed. An indication that a first user and a second user have at least one shared chromosomal segment is received. Information about the second user is obtained. A characteristic of the first user is inferred based at least in part on the information about the second user.
Type:
Grant
Filed:
July 31, 2017
Date of Patent:
December 1, 2020
Assignee:
23andMe, Inc.
Inventors:
John Michael Macpherson, Brian Thomas Naughton, Joanna Louise Mountain
Abstract: Determining relative connections between individuals includes: obtaining identification information of a first individual and identification information of a second individual; determining, based at least in part on a relative connections graph, a relative connections path connecting the first individual, the second individual, and at least one additional individual; and outputting information pertaining to the relative connections path.
Abstract: Presenting ancestral origin information, comprising: receiving a request to display ancestry data of an individual; obtaining ancestry composition information of the individual, the ancestry composition information including information pertaining to a proportion of the individual's genotype data that is deemed to correspond to a specific ancestry; and presenting the ancestry composition information to be displayed.
Type:
Grant
Filed:
March 13, 2013
Date of Patent:
June 14, 2016
Assignee:
23andMe, Inc.
Inventors:
Chuong Do, Eric Durand, John Michael Macpherson
Abstract: Assembling a cohort includes: receiving genetic characteristic information pertaining to a desired genetic characteristic; using the genetic characteristic information to search a data storage comprising information of previously genotyped individuals to derive a candidate group having the desired genetic characteristic; and assembling the cohort based at least in part on the candidate group.
Type:
Grant
Filed:
December 15, 2020
Date of Patent:
September 5, 2023
Assignee:
23andMe, Inc.
Inventors:
Arnab Chowdry, Alexander Kompel, Michael Polcari
Abstract: Assembling a cohort includes: receiving genetic characteristic information pertaining to a desired genetic characteristic; using the genetic characteristic information to search a data storage comprising information of previously genotyped individuals to derive a candidate group having the desired genetic characteristic; and assembling the cohort based at least in part on the candidate group.
Type:
Grant
Filed:
February 17, 2015
Date of Patent:
August 2, 2016
Assignee:
23andMe, Inc.
Inventors:
Arnab Chowdry, Alexander Kompel, Michael Polcari
Abstract: Presenting ancestral origin information, comprising: receiving a request to display ancestry data of an individual; obtaining ancestry composition information of the individual, the ancestry composition information including information pertaining to a proportion of the individual's genotype data that is deemed to correspond to a specific ancestry; and presenting the ancestry composition information to be displayed.
Type:
Grant
Filed:
July 24, 2018
Date of Patent:
February 25, 2020
Assignee:
23andMe, Inc.
Inventors:
Chuong Do, Eric Durand, John Michael MacPherson
Abstract: Determining relative connections between individuals includes: obtaining identification information of a first individual and identification information of a second individual; determining, based at least in part on a relative connections graph, a relative connections path connecting the first individual, the second individual, and at least one additional individual; and outputting information pertaining to the relative connections path.
Abstract: Assembling a cohort includes: receiving genetic characteristic information pertaining to a desired genetic characteristic; using the genetic characteristic information to search a data storage comprising information of previously genotyped individuals to derive a candidate group having the desired genetic characteristic; and assembling the cohort based at least in part on the candidate group.
Type:
Grant
Filed:
October 11, 2011
Date of Patent:
March 24, 2015
Assignee:
23andMe, Inc.
Inventors:
Arnab Chowdry, Alexander Kompel, Michael Polcari
Abstract: Assembling a cohort includes: receiving genetic characteristic information pertaining to a desired genetic characteristic; using the genetic characteristic information to search a data storage comprising information of previously genotyped individuals to derive a candidate group having the desired genetic characteristic; and assembling the cohort based at least in part on the candidate group.
Type:
Grant
Filed:
July 1, 2016
Date of Patent:
December 25, 2018
Assignee:
23andMe, Inc.
Inventors:
Arnab Chowdry, Alexander Kompel, Michael Polcari
Abstract: A method, software, database, and system in which a query attribute is used as the basis for accessing stored attribute combinations and their frequencies of occurrence for individuals; and tabulating, based on frequencies of occurrence, those attribute combinations that are most likely to co-occur with the query attribute.
Type:
Grant
Filed:
October 3, 2022
Date of Patent:
April 4, 2023
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering
Abstract: Presenting ancestral origin information, comprising: receiving a request to display ancestry data of an individual; obtaining ancestry composition information of the individual, the ancestry composition information including information pertaining to a proportion of the individual's genotype data that is deemed to correspond to a specific ancestry; and presenting the ancestry composition information to be displayed.
Type:
Grant
Filed:
June 19, 2019
Date of Patent:
August 25, 2020
Assignee:
23andMe, Inc.
Inventors:
Chuong Do, Eric Durand, John Michael Macpherson
Abstract: Processing genetic information comprises: receiving an input that includes information pertaining to a specific genetic variant; and identifying, in a database comprising genotype information of a plurality of candidate individuals, a matching individual imputed to have the specific genetic variant. The genotype information of the matching individual corresponding to the specific genetic variant is not directly assayed.
Type:
Grant
Filed:
September 2, 2016
Date of Patent:
September 15, 2020
Assignee:
23andMe, Inc.
Inventors:
Arnab Chowdry, Geoffrey Benton, Brian Thomas Naughton
Abstract: Presenting ancestral origin information, comprising: receiving a request to display ancestry data of an individual; obtaining ancestry composition information of the individual, the ancestry composition information including information pertaining to a proportion of the individual's genotype data that is deemed to correspond to a specific ancestry; and presenting the ancestry composition information to be displayed.
Type:
Grant
Filed:
June 13, 2016
Date of Patent:
June 30, 2020
Assignee:
23andMe, Inc.
Inventors:
Chuong Do, Eric Durand, John Michael Macpherson
Abstract: Displaying an indication of ancestral data is disclosed. An indication that a genetic interval corresponds to a reference interval that has a likelihood of having one or more ancestral origins is received. One or more graphic display parameters are determined based at least in part on the indication. An indication of the one or more ancestral origins is visually displayed using the one or more graphic display parameters.
Type:
Grant
Filed:
November 22, 2022
Date of Patent:
April 11, 2023
Assignee:
23andMe, Inc.
Inventors:
John Michael Macpherson, Brian Thomas Naughton, Joanna Louise Mountain