Abstract: A system and system for personal pathogen status verifying allows an entity to control access to an area of congregation (AOC) at one or more points of entry (POE) is a configurable manner. In one embodiment, the system may be used for the SARS-CoV-2 virus, but may be similarly used for other pathogens.
Abstract: This application relates to isolated proteins comprising an amino acid sequence which comprises at least 2 mutations relative to a SARS-CoV-2 Spike protein template sequence, isolated nucleic acid encoding said proteins, and vaccine compositions comprising said proteins.
Abstract: Disclosed herein are glycan-coated RBD immunogens, engineered nanoparticle vaccines comprising glycan-coated RBD immunogens and methods of use thereof for SARS-COV-2 vaccines.
Type:
Application
Filed:
April 20, 2022
Publication date:
June 6, 2024
Inventors:
Daniel Kulp, Yuanhan Wu, Kylie M. Konrath, Kevin Liaw, Ziyang Xu, David Weiner
Abstract: Described herein are orally-bioavailable nucleoside analogs and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of coronavirus infections, including SARS-CoV-2 infection.
Type:
Grant
Filed:
January 25, 2023
Date of Patent:
October 1, 2024
Assignee:
VENATORX PHARMACEUTICALS, INC.
Inventors:
Christopher J. Burns, Glen Coburn, Guo-Hua Chu, Stephen M. Condon, Steven A. Boyd, Daniel C. Pevear
Abstract: Compounds and compositions, for example vardenafil, for treating diseases and/or conditions caused by, arising from, and/or associated with coronavirus in a subject, for example a subject infected with SARS-CoV-2 or other coronavirus. Combinations of agents useful for treating diseases and/or conditions caused by, arising from, and/or associated with coronavirus in a subject, for example, vardenafil and Remdesivir, are also provided.
Type:
Application
Filed:
March 3, 2021
Publication date:
April 20, 2023
Inventors:
Wai Yip Thomas LEE, Chung Sing Daniel POON
Abstract: The present invention includes compositions and methods of making and using an immunogenic protein for mucosal delivery comprising at least 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% amino acid identity to a multigenic coronavirus vaccine on a modified vaccinia ankara (MVA) vector that expresses a viral nucleoprotein (N) protein and a spike (S) protein.
Abstract: An electronic apparatus capable of reducing specific absorption rate (SAR) is disclosed. The antenna device includes an antenna element to which power is supplied, and at least one resonant antenna element which is disposed such that the longitudinal direction thereof and the longitudinal direction of the antenna element are substantially parallel to each other and which can resonate with the antenna element.
Abstract: A single-end input configurable Successive Approximation Register Analog-to-Digital Converter (SARADC) allows for the input configuration as single-ended or differential inputs without adding extra circuitry. In both configurations, the ADC maintains the same LSB voltage and output code range. Furthermore, when configured as a single-ended input, power consumption is further reduced.
Abstract: The present disclosure provides compositions and methods useful for preventing and/or treating coronavirus infection. As described herein, the compositions and methods are based on development of immunogenic compositions that include virus-like particles (VLPs) which comprise one or more Moloney Murine leukemia virus (MMLV) core proteins and include a spike protein from the Beta variant of SARS-Cov-2.
Type:
Application
Filed:
January 12, 2022
Publication date:
July 28, 2022
Inventors:
David Evander Anderson, Anne-Catherine Fluckiger
Abstract: Methods and apparatus for ATM segmentation and reassembly (SAR) which provide efficient transfer of ATM cell data between an ATM network and a set top box or other processing system. Reassembly operations are performed using a receive ring which stores an array of pointers. Each of the pointers specifies the address of a cell buffer suitable for storing a received ATM cell. Received ATM cells are first filtered to determine if the cells should be accepted. When a given cell is accepted, a pointer retrieved from the receive ring is used to determine the address of a cell buffer in which that cell will be stored. Host CPU software directing the operation of the SAR device periodically services the receive ring to prevent overflow. The host CPU software services the receive ring by sequentially stepping through the ring entries and linking the pointer for each stored cell into a chain of pointers maintained for the VCI on which that stored cell was received.
Abstract: The invention relates to a method of treating a viral infection caused by or associated with SARS-CoV-2 in a subject, the method comprising administering to the subject by inhalation intraorally and/or intranasally a therapeutically effective amount of a formulation comprising niclosamide, or a pharmaceutically acceptable salt thereof, and a cyclodextrin.
Type:
Application
Filed:
April 18, 2022
Publication date:
October 13, 2022
Inventors:
Morten Otto Alexander Sommer, Rasmus Toft-Kehler, Anne Katrine Toft-Kehler, Günter Ditzinger, Mads Jellingsoe, Phillippe Andres, Matthias Knopp
Abstract: The invention describes compositions and methods for detecting and/or quantifying an RNA or DNA pathogen in a sample. The method comprises a two-round real-time nested PCR, which allows detection of less than 10 copies of RNA or DNA of the pathogen in a sample. The method of the invention is useful for fast, reliable, and sensitive detection and/or quantification of SARS-CoV in a sample.
Abstract: Process for the preparation of propylene from a hydrocarbon feed, wherein the hydrocarbon feed is an essentially olefinic hydrocarbon feed comprising C6 olefins and wherein the hydrocarbon feed is contacted with a one-dimensional zeolite having 10-membered ring channels and a silica to alumina ratio (SAR) in the range from 10 to 200.
Type:
Application
Filed:
May 16, 2007
Publication date:
October 29, 2009
Inventors:
Leslie Andrew Chewter, Michiel Johannes Franciscus Maria Verhaak, Jeroen Van Westrenen
Abstract: The disclosure provides an immunogenic composition comprising an haptenized Spike protein (S protein) or fragment thereof from a coronavirus and at least one pharmaceutically acceptable carrier, wherein the coronavirus comprising severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Further disclosed are methods of using the haptenized S proteins from coronavirus or immunizing a subject against coronavirus infection.
Abstract: A self-reporting system and system for personal pathogen status verifying allows an entity to control access to an area of congregation (AOC) at one or more points of entry (POE) is a configurable manner. In one embodiment, the system may be used for the SARS-CoV-2 virus, but may be similarly used for other pathogens.
Abstract: The present invention relates to a washer/dryer (1) comprising a drum (2) wherein the laundry is placed and at least one drum baffle (3) extending in the radial direction towards the center of the drum (2) for tumbling the laundry and wherein the interior of the drum (2) is illuminated effectively.
Abstract: An embodiment provides a method for detection of the COVID-19 virus, including: obtaining a body fluid from a patient; exposing the body fluid to at least one binding antibody, wherein the at least one binding antibody binds to an antigen in the body fluid; forming an antigen antibody complex; and determining the presence of the antigen antibody complex. Other aspects are described and claimed.
Abstract: Electrical stimulation of neural activity in the neural innervation of the spleen that is associated with neurovascular bundles provides a useful way to treat acute medical conditions, such as trauma, hemorrhaging, shock, acute respiratory distress syndrome (ARDS), severe respiratory distress syndrome (SARS), and coronavirus disease 19 (COVID-19).
Abstract: The present invention in an embodiment relates generally to an air purifier having an ultraviolet wave chamber which is accessible from the exterior designed for the placement of masks/respirators in need of decontamination. Such device preferably makes use of filters comprising copper foam.
Type:
Grant
Filed:
July 22, 2020
Date of Patent:
February 2, 2021
Inventors:
Cullen Thomas Moore, Neha Varma Nadimpally
Abstract: Detection of an increase in a mismatch of an antenna of a radio frequency (RF) device and/or a change in a capacitance value of the antenna indicates proximity of a body to the antenna. Upon detection of proximity of a body to the antenna, reduction of transmit power of the RF device may be done to meet Specific Absorption Rate (SAR) level regulations.