Abstract: A method for operating a propulsion device having a propulsor with a propeller, the propulsion device having a base coupled to a marine vessel and being configured to propel the marine vessel in water. The method includes moving the propulsor from a deployed position towards a stowed position, where the propulsor is closer to the marine vessel in the stowed position than in the deployed position, and where the propulsor is configured to propel the marine vessel in the deployed position. The method further includes rotating the propeller so as to fit between sides of the base coupled to the marine vessel when the propulsor is in the stowed position.

Abstract: A method is provided for activating a secondary battery having a negative electrode, a positive electrode, and a microporous separator between the negative and positive electrodes permeated with carrier-ion containing electrolyte, the negative electrode having anodically active silicon or an alloy thereof. The method includes transferring carrier ions from the positive electrode to the negative electrode to at least partially charge the secondary battery, and transferring carrier ions from an auxiliary electrode to the positive electrode, to provide the secondary battery with a positive electrode end of discharge voltage Vpos,eod and a negative electrode end of discharge so voltage Vneg,eod when the cell is at a predefined Vcell,eod value, the value of Vpos,eod corresponding to a voltage at which the state of charge of the positive electrode is at least 95% of its coulombic capacity and Vneg,eod is at least 0.4 V (vs Li) but less than 0.9 V (vs Li).

Abstract: Phosphonate linkers and their use for delivering compounds with passive cell permeability into a cell wherein the phosphonate group facilitates cellular retention of the compound are described.

Abstract: The present disclosure provides nucleic acid carriers comprising targeting agents, pharmaceutical compositions comprising the same, and methods of making and using the same.

Abstract: Methods and materials for volumetric additive manufacturing, including computed axial lithography (“CAL”), using photosensitive resins comprising a photocurable resin prepolymer; a photoinitiator; and (optionally) a curing inhibitor. In various embodiments, such photosensitive polymers comprise (a) one or more monomer (or prepolymer) molecules, which form the backbone of the polymer network of the polymeric material and define its architecture; and (b) a photoinitiator that captures illumination energy and initiates polymerization.

Abstract: Provided herein are agents, such as antibodies and chimeric antigen receptors, that target HSP70. Methods of treating cancer are provided, comprising administering to a patient in need thereof an effective amount of an HSP70-targeting agent. The HSP70-specific antibody may enhance uptake of HSP70 by antigen presenting cells.

Abstract: A controller for positioning a patient utilizing an inflatable device is provided. The inflatable device may include three independently inflatable chambers. The controller may include first, second, and third pressure output ports; first, second, and third pressure sensors; a plurality of electro-mechanical switches; an electronic user interface; an computer; a pressurized air input port; and an atmospheric air port. The plurality of electro-mechanical switches may be configured to independently control air flow through the first, second, and third pressure output ports. The first, second, and third pressure sensors may be configured to measure pressure internal to the first, second, and third pressure output ports, respectively.

Abstract: A catheter blood pump includes a cannula with an expandable central portion having a proximal end, a distal end and a blood flow conduit therebetween. A flexible inlet portion at the distal end is provided with a plurality of spaced apart inlet struts configured to prevent an obstruction from entering, and a flexible outlet portion is provided with a plurality of spaced apart outlet struts operative to reduce a swirl velocity of blood, wherein the plurality of spaced apart inlet struts and the plurality of spaced apart outlet struts are fabricated from a collapsible shape memory material.

Abstract: An inflatable device for patient positioning is provided. The inflatable device may include a first inflation chamber subsystem, a second inflation chamber subsystem, a third inflation chamber subsystem. At least a portion of the first inflation chamber subsystem may be conspicuously marked with a first color. At least a portion of the second inflation chamber subsystem may be conspicuously marked with a second color. At least a portion of the third inflation chamber subsystem may conspicuously marked with a third color. The first, second, and third colors may be visually distinct.

Abstract: A method of positioning a patient utilizing an inflatable device is provided. In one example, plurality of patient metrics may be received. A first chamber pressure target value, a second chamber pressure target value, and a third chamber pressure target value may be determined based on the plurality of patient metrics. The device may be inflated. The step of inflating the device may include inflating a first, second, and third chambers of the at least three independently inflatable chambers to the first, second, and third chamber pressure target values, respectively. A controller configured to execute the method may also be provided.

Abstract: A pallet cover suitable for use in covering at least a portion of a payload on a pallet and a kit for use in making the pallet cover. In one embodiment, the pallet cover includes a top wall, a front wall, a rear wall, a left side wall, and a right side wall, wherein the walls are detachably joined to one another. Each of the top wall, the front wall, the rear wall, the left side wall, and the right side wall includes a first fabric sheet and a second fabric sheet, the first and second fabric sheets being joined together to form a plurality of pockets. Each pocket may removably receive a temperature-control member containing a phase-change material. At least one of the top wall, the front wall, the rear wall, the left side wall and the right side wall includes a plurality of detachably joined portions.

Abstract: According to one or more embodiments herein, interferometry-based satellite location accuracy is provided.

Abstract: A pallet cover suitable for use in covering at least a portion of a payload on a pallet and a kit for use in making the pallet cover. In one embodiment, the pallet cover includes a top wall, a front wall, a rear wall, a left side wall, and a right side wall, wherein the walls are detachably joined to one another. Each of the top wall, the front wall, the rear wall, the left side wall, and the right side wall includes a first fabric sheet and a second fabric sheet, the first and second fabric sheets being joined together to form a plurality of pockets. Each pocket may removably receive a temperature-control member containing a phase-change material. At least one of the top wall, the front wall, the rear wall, the left side wall and the right side wall may include a plurality of detachably joined portions.

Abstract: A bolted hinge assembly is provided for a waterbox cover (a “waterbox hinge assembly”). The waterbox hinge assembly generally does not require welding on the waterbox cover or the heat exchanger in an HVAC system (“HVAC unit” hereinafter). Further, the waterbox hinge assembly may be installable to the HVAC unit without removing the heat exchange fluids (e.g., water, refrigerant, etc.) from the HVAC unit. In some cases, the waterbox hinge assembly can be installed on an HVAC unit without removing any bolts from the waterbox cover. Once installed, the waterbox hinge assembly can be left in place so that it can be reused anytime the HVAC unit is serviced.

Abstract: A reaching and grabbing tool is provided. The tool includes a trigger assembly having a trigger and a handle. A jaw assembly is provided having at least one jaw operably connected to the trigger to move the at least one jaw. A hinge assembly is disposed between the trigger assembly and the jaw assembly, the hinge assembly being selectively lockable between an operating position and a folded position.

Abstract: Novel compounds, compositions, and methods of using and preparing the same, which may be useful for treating alpha-1 antitrypsin deficiency (AATD).

Abstract: Provided is a new digital music storage and readout system and method that incorporates layers of anti-pirating features to inhibit unauthorized reproduction of device music content. This concept and device design may be extended to video storage and playback.

Abstract: A supportive clothing article for a wearable cardioverter defibrillator (WCD), including a belt, the belt including a first end with a first portion of a fastener and a second end with a second portion of the fastener, wherein the belt is structured to fasten around the torso of patient below the chest area of the patient, the belt including a first conductive mesh portion adjacent the first end of the belt or the second end of the belt, two straps, a back portion extending from the belt at an intermediary position on the belt to each of the two straps, the back portion including a conductive mesh, a first support receptacle attached to and extending from the belt and attachable to one of the two straps, and a second support receptacle attached to and extending from the belt and attachable to the other of the two straps.