Abstract: Disclosed herein are washable, reusable, antimicrobial and antiviral face masks and methods of their use for the reduction of transmission of infectious pathogens. Exemplary face masks are made of silver-coated material wherein activation of the silver from moisture in a user's breath kills pathogens. The disclosed face masks are useful in reducing, inhibiting or killing pathogens, such as SARS-CoV-2, that contact the face mask within 2 hours of continuous contact.
Abstract: This disclosure describes methods for prophylaxis and treatment of coronavirus in vulnerable populations and infected individuals. The methods include the administration of zinc and in some embodiments copper. In some embodiments, an amount of zinc is administered sufficient to raise serum zinc levels to 60 ?g/dL. In some aspects, the coronavirus is the SARS-CoV-2 virus and/or the infection is COVID-19.
Type:
Application
Filed:
April 20, 2021
Publication date:
October 21, 2021
Inventors:
Fredericus J. van Kuijk, Scott W. McPherson
Abstract: The present disclosure provides compositions and methods useful for preventing and/or treating coronavirus infection. As described herein, the compositions and methods are based on development of immunogenic compositions that include virus-like particles (VLPs) which comprise one or more Moloney Murine leukemia virus (MMLV) core proteins and include one or more coronavirus epitopes, such as, for example, from SARS-Cov-2 spike protein.
Type:
Application
Filed:
March 30, 2021
Publication date:
November 18, 2021
Inventors:
David Evander Anderson, Anne-Catherine Fluckiger
Abstract: A method of treating or preventing a Coronaviridae infection in a subject comprising administrating a therapeutically effective amount of a compound of Formula I or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the Coronaviridae comprises at least one selected from 2019-nCov virus, HCov 229E virus, SARS virus, MERS virus,
Type:
Application
Filed:
June 4, 2020
Publication date:
September 22, 2022
Inventors:
Jian CUI, Minglong HU, Yao YU, Along ZHAO, Faming ZHANG
Abstract: The example non-limiting technology herein provides a Synthetic Aperture Radar (SAR) solution on board a micro-satellite that provides global revisit within 1 month; a cost below US$ 10 million; and satellite mass lower than 100 kg. One solution uses an inflatable Cassegrain type antenna with a phased beam steering array in the 1.2 GHz band.
Abstract: Disclosed are hydroxychloroquine or chloroquine, or a geometric isomer thereof, or a pharmaceutically acceptable salt thereof, and/or a solvate thereof, and/or a hydrate thereof, and a pharmaceutical composition containing the above-mentioned compound, and the use thereof in the treatment of diseases or infections caused by SARS-CoV-2.
Abstract: An apparatus for rocking a piece of furniture to which it is attached. The rocking apparatus includes at least one rolling mechanism that, when in operation, rotates the rolling mechanism around an axis of rotation causing a rocking action. The apparatus may be utilized for rocking a variety of pieces of furniture such as a safety infant car seat, a stroller seat, a rocking chair, a swing or a hammock. According to some embodiments the rolling mechanism is connected to a driving portion.
Abstract: The invention relates to the use of Angiotensin Converting enzyme 2 (ACE2) for the preparation of a medicament for the treatment of severe acute lung injury, especially induced by acid aspiration or sepsis, of lung oedemas and lung injuries and failures connected with infection with severe acute respiratory Syndrome (SARS) Coronavirus.
Abstract: Methods for prophylaxis, treatment, and reduction of infection, re-infection, and transmission rates of Coronaviruses and more particularly Coronavirus Disease 2019 (COVID-19) resulting from a SARS-CoV-2 viral infection with the use of a pharmaceutical preparation comprising one or more coated or uncoated digestive enzymes, such as pancreatic enzymes and porcine pancreatic enzymes are described herein.
Type:
Application
Filed:
December 8, 2022
Publication date:
April 13, 2023
Inventors:
Joan M. FALLON, Matthew HEIL, James J. FALLON, Janice HUGHES
Abstract: The disclosure is directed to methods of inhibiting coronavirus infection using a hydrocarbon stapled peptide which is a peptidomimetic of the human angiotensin-converting enzyme 2 (hACE2). The hydrocarbon stapled peptide binds to the receptor binding domain (RBD) of a coronavirus spike protein (S) and inhibits binding of the coronavirus to hACE2 expressed on the surface of host cells.
Type:
Application
Filed:
December 22, 2021
Publication date:
February 15, 2024
Inventors:
Yu TIAN, Sicheng JIANG, Jeffrey A. HUBBELL, Matthew A. TIRRELL, James L. LABELLE
Abstract: Covid-19 is caused by a highly transmissible novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or a variant thereof. Current available therapeutic modalities have significant efficacy issues. Described herein are methods of preventing, reversing, and/or treating a Covid-19 infection by administering an inhibitor of CHI3L1.
Type:
Application
Filed:
May 19, 2021
Publication date:
June 15, 2023
Inventors:
Jack A. ELIAS, Chun Geun LEE, Bing MA, Suchitra KAMLE, Changmin LEE
Abstract: The subject matter disclosed herein relates to a recombinant spike (S) protein from the B.1.351.2-7 variant of the SARS-CoV-2 virus, the DNA and RNA nucleotide sequences encoding the recombinant B.1.351.2-7 spike protein, and engineered antibodies that bind the B.1.351.2-7 spike protein and neutralize the B.1.351.2-7 virus.
Type:
Application
Filed:
April 27, 2022
Publication date:
July 11, 2024
Inventors:
David D. HO, Yaoxing HUANG, Manoj S. NAIR
Abstract: A client information handling system application selectively communicates network packets simultaneously through plural network interfaces by leveraging network address translation at the network layer of the network packets. Network packets are distributed across the plural network interfaces to achieve desired network communication goals, such as bandwidth, data rates, quality of service, reliability and SAR requirements.
Abstract: The present disclosure provides methods for treating or preventing an infectious disease or condition, such as the COVID-19 virus (SARS-CoV-2), by administering a therapeutically effective amount of taxifolin to a subject in need thereof, wherein the taxifolin is administered to the subject in combination with a therapeutically effective amount of one or more additional therapeutic agents.
Abstract: Uses and formulations of cannabinoids, in particular of cannabidiol, are provided. The cannabinoids, in particular cannabidiol, are used for the treatment of patients suffering from COVID-19, a disease caused by the coronavirus SARS-Cov-2. Formulations are especially for oral administration of cannabinoids, in particular of cannabidiol. These formulations are useful for treating patients suffering from COVID-19.
Type:
Application
Filed:
May 11, 2020
Publication date:
June 15, 2023
Applicant:
ADD Advanced Drug Delivery Technologies Ltd.
Inventors:
Reinhard Nowak, Mirko Nowak, Jesko Jay Nowak, Norbert Pöllinger
Abstract: A new octapeptide having profound angiotensin antagonist properties has been found. The new compound resembles angiotensin II except for the two terminal amino acids, carrying unnatural amino acids at the N-terminus, and at the C-terminus.
Type:
Grant
Filed:
February 10, 1975
Date of Patent:
August 24, 1976
Inventors:
Francis Merlin Bumpus, Mahesh Chandra Khosla, Robert Rudolph Smeby
Abstract: Compounds useful as components of immunogenic compositions for the induction of an immunogenic response in a subject against infection, methods for their use in treatment, and processes for their manufacture are provided herein. The compounds comprise a nucleic acid construct comprising a sequence which encodes an antigen, in particular a Coronavirus antigen.
Type:
Application
Filed:
April 16, 2021
Publication date:
November 16, 2023
Applicant:
GlaxoSmithKline Biologicals SA
Inventors:
Dong YU, Giulietta MARUGGI, Jason W. WESTERBECK, Jeffrey B. ULMER, Jason P. LALIBERTE, Kate LUISI, Lin QU
Abstract: Provided is a method for reducing N2O emissions in an exhaust gas comprising contacting an exhaust gas containing NH3 and an inlet NO concentration with an SCR catalyst composition containing small pore zeolite having an SAR of about 3 to about 15 and having about 1-5 wt. % of an exchanged transition metal.
Type:
Application
Filed:
March 23, 2015
Publication date:
September 24, 2015
Inventors:
Joseph Michael FEDEYKO, Alexander Nicholas Michael GREEN, Guy Richard CHANDLER, Jillian Elaine COLLIER, Hai-Ying CHEN
Abstract: The invention relates generally to coronavirus disease 2019 (COVID-19) and more particularly to the prediction of severity of COVID-19 manifestation in a patient or in an individual at risk of infection by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) based on a level of chemokine (C-X-C motif) ligand 16 (CXCL 16) expression in and/or the rs 10490770 genotype of the patient or individual.
Abstract: A communication method for communicating information through a telecommunications network. The telecommunications network comprises includes at least one server and at least one terminal exchanging a dataset. The terminal is configured so as to implement an Internet browser and the communication method is executed by the Internet browser. The communication method includes a step of analysing said dataset, which consists of at least one element from among: an object element, a branch element and a display element.