Abstract: Phosphonate linkers and their use for delivering compounds with passive cell permeability into a cell wherein the phosphonate group facilitates cellular retention of the compound are described.

Abstract: Disclosed herein are quantum dot devices and techniques. In some embodiments, a quantum computing processing device may include a quantum well stack, an array of quantum dot gate electrodes above the quantum well stack, and an associated array of selectors above the array of quantum dot gate electrodes. The array of quantum dot gate electrodes and the array of selectors may each be arranged in a grid.

Abstract: A maritime sulfur dioxide emissions switch monitoring system has an emissions sampling apparatus that is self-powered and requires a low power for operation. The emissions sampling apparatus has sensitive and selective chemical sensing technology capable of quantification of sulfur dioxide and carbon dioxide. Relative humidity, temperature and pressure sensors, in addition to sulfur dioxide and carbon dioxide are used for monitoring the exhaust gas. Filters are used to eliminate solid and liquid aerosolized components in marine engine exhaust.

Abstract: An optoelectronic device grown on a miscut of GaN, wherein the miscut comprises a semi-polar GaN crystal plane (of the GaN) miscut x degrees from an m-plane of the GaN and in a c-direction of the GaN, where ?15<x<?1 and 1<x<15 degrees.

Abstract: An auxiliary electrode includes a conductive layer having a first major surface in an X-Y plane, the conductive layer is electrically conductive and has a first surface area. The auxiliary electrode includes a first carrier ion supply layer and a second carrier ion supply layer, each carrier ion supply layer comprising a material that supplies carrier ions for an electrode of the secondary battery. The first carrier ion supply layer covers a first region of the first major surface of the conductive layer and the second carrier ion supply layer covers a second region of the first major surface of the conductive layer. The first and second regions are separated by a third region, the third region configured to be folded such that the first region and the second region are substantially parallel, and the third region is substantially perpendicular to the first and second regions in the folded configuration.

Abstract: Methods of braiding using a braiding mechanism are described. The braiding mechanism includes a disc defining a plane and a circumferential edge, a mandrel extending from a center of the disc that is adapted to hold a plurality of filaments extending radially from the mandrel toward the circumferential edge of the disc, a plurality of catch mechanisms positioned circumferentially around the edge of the disc, a plurality of actuators adapted to move the plurality of catch mechanisms in a substantially radial direction relative to the circumferential edge of the disc, and a plurality of filaments extending radially from the mandrel towards circumferential edge of the disc. A middle portion of each filament of the plurality of filaments contacts an end of the mandrel.

Abstract: A method of forming a three-dimensional object is carried out by: (a) providing a carrier and an optically transparent member having a build surface, the carrier and the build surface defining a build region therebetween; (b) filling the build region with a polymerizable liquid, the polymerizable liquid including a mixture of (i) a light polymerizable liquid first component, and (ii) a second solidifiable component that is different from the first component; (c) irradiating the build region with light through the optically transparent member to form a solid polymer scaffold from the first component and also advancing the carrier away from the build surface to form a three-dimensional intermediate having the same shape as, or a shape to be imparted to, the three-dimensional object, and containing the second solidifiable component carried in the scaffold in unsolidified and/or uncured form; and (d) concurrently with or subsequent to the irradiating step, solidifying and/or curing the second solidifiable compone

Abstract: A dry powder inhaler includes a powder storage element configured to hold a powdered medicament and an inlet channel receives, powdered medicament from the powder storage element that is entrained in an airflow. The inlet channel has a first diameter and defines an opening. The inhaler includes a dispersion chamber that receives the airflow and the powdered medicament from the opening. The dispersion chamber has a second diameter. The inhaler includes an actuator housed within the dispersion chamber. The actuator oscillates within the dispersion chamber when exposed to the airflow to deaggregate the powdered medicament entrained by the airflow passing through the dispersion chamber. A ratio between the first diameter and the second diameter is between about 0.40 and 0.60 such that an audible sound is produced as the actuator oscillates. The inhaler includes an outlet channel through which the airflow and powdered medicament exit the inhaler.

Abstract: A pool or spa system includes networked pool or spa devices that can be dynamically configured with network address by a controller. The controller can transmit a device discovery request on a network and can receive a discovery response from pool or spa devices that require a network address. The system determines and assigns the network addresses for the pool or spa devices based on unique device identifiers associated with the responding pool or spa devices. The network addresses assigned to the pool or spa device are transmitted to the pool or spa device to be used by the pool or spa devices to communicate with the controller over the network. The system can be used to discover and assign addresses to various types of pool or spa devices, such as pumps, underwater lights, chlorinators, water feature controllers, remote controllers, and/or other types of devices.

Abstract: The present invention relates to compositions comprising TWIST signaling inhibitors and optionally one or more anti-cancer agents, and methods of using the compositions for the treatment of cancer.

Abstract: A system for off-chain management, distribution and auditing of decentralized cryptocurrency is provided. The system enables an organization to mint off-chain, centrally controlled tokens for internal distribution within the organization. The system allows these tokens to be assigned an underlying value in a cryptocurrency and to be associated with distribution rules and withdrawal rules. When a token is distributed to an employee, it does not guarantee that the employee will receive the underlying value in the cryptocurrency. Instead, the token represents the employee's ability to withdraw up to the assigned underlying value in the cryptocurrency, which the organization can approve, adjust or deny. When the organization approves an employee's withdrawal of a token's underlying value, the system can manage the distribution of the token's underlying value to the employee's cryptocurrency wallet and can provide functionality for tracking, reporting and auditing such transactions.

Abstract: A method of forming a three-dimensional object, wherein said three-dimensional object is an insert for use between a helmet and a human body, is described. The method may use a polymerizable liquid, or resin, useful for the production by additive manufacturing of a three-dimensional object, comprising a mixture of (i) a light polymerizable liquid first component, and (ii) a second solidifiable component that is different from said first component.

Abstract: A quality control system analyzes the quality of a battery cell, with the battery cell defining a gas pouch configured to expand from a deflated configuration to an inflated configuration when filled with a gas formed during a cell formation process. The system comprises a computational system comprising a processor and a memory and a measurement instrument in electronic communication with the computational system. The measurement instrument is arranged to measure a distance defined by the gas pouch and transmit a signal to the computational system corresponding to the distance. The computational system is arranged to analyze the distance with the processor and determine a volumetric measurement of the gas within the gas pouch and compare the volumetric measurement to a threshold in the memory to assess a quality score for the battery cell. A corresponding method analyzes the quality of the battery cell with the quality control system.

Abstract: An optical metasurface film includes a flexible polymeric film having a first major surface, a patterned polymer layer having a first surface proximate to the first major surface of the flexible polymeric film and having a second nanostructured surface opposite the first surface, and a refractive index contrast layer adjacent to the nanostructured surface of the patterned polymer layer forming a nanostructured bilayer with a nanostructured interface. The nanostructured bilayer acts locally on amplitude, phase, or polarization of light, or a combination thereof and imparts a light phase shift that varies as a function of position of the nano structured bilayer on the flexible polymeric film. The light phase shift of the nanostructured bilayer defines a predetermined operative phase profile of the optical metasurface film.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems and methods for connecting a lead to an implantable medical device. The apparatuses, systems and methods may include a clamp arranged within a connector port configured to secure the lead with a header in response to frictional engagement between a portion of the implantable lead and the clamp.

Abstract: Memory devices and systems with automatic background precondition upon powerup, and associated methods, are disclosed herein. In one embodiment, a memory device includes a memory array having a plurality of memory cells and a fuse array configured to store precondition data. The precondition data can identify a portion of the memory array, specify a predetermined precondition state, or a combination thereof. When the memory device powers on, the memory device can be configured to automatically retrieve the precondition data from the fuse array and/or to write memory cells in the portion of the memory array to the predetermined precondition state before executing an access command.

Abstract: The present disclosure includes apparatuses and methods related to a non-deterministic memory protocol. An example apparatus can perform operations on the memory device based on commands received from a host according to a protocol, wherein the protocol includes non-deterministic timing of the operations. The memory device can be a non-volatile dual in-line memory module (NVDIMM) device.

Abstract: A forceps includes an end effector assembly having first and second jaw members movable between a spaced-apart position and an approximated position for grasping tissue therebetween. A knife assembly having a cutting blade disposed at a distal end thereof is also provided. The knife assembly is translatable relative to the end effector assembly between a retracted position and an extended position, wherein the cutting blade extends between the jaw members to cut tissue grasped therebetween. The knife assembly includes a proximal component and a first distal component that includes the cutting blade. The proximal and first distal components are removably coupled to one another to facilitate replacement of the first distal component. Methods of preparing such forceps for reuse are also provided.

Abstract: A transfer case pump includes an oil pump, a cover assembly, and a torque transfer mechanism. The oil pump has a pump shaft, and is configured to pressurize a lubricant in response to a rotation of the pump shaft. The pump shaft rotates around a pump axis. The pump axis is parallel to a rear axis of a rear shaft. The pump axis is offset from the rear axis. The cover assembly has a channel configured to transfer the lubricant from the oil pump to the rear shaft. The cover assembly extends around the rear shaft and around the pump shaft. The torque transfer mechanism is configured to transfer a torque from the rear shaft to the pump shaft.

Abstract: A computer-implemented method comprising: controlling input of data quantifying damage received by a compressor of a gas turbine engine into a first machine learning algorithm; receiving data quantifying a first operating parameter of the compressor as an output of the first machine learning algorithm; and determining operability of the compressor by comparing the received data quantifying the first operating parameter of the compressor with a threshold.