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  • PHOSPHOR PLATES FOR LEDS FROM STRUCTURED FILMS
    Publication number: 20100244067
    Abstract: The invention relates to a phosphor element which is based on natural and/or synthetic flake-form substrates, such as mica, corundum, silica, glass, ZrO2 or TiO2, and at least one phosphor, to the production thereof, and to the use thereof as LED conversion phosphor for white LEDs or so-called colour-on-demand applications.
    Type: Application
    Filed: October 25, 2007
    Publication date: September 30, 2010
    Applicant: MERCK PATENT GESELLSCHAFT
    Inventors: Holger Winkler, Klaus Ambrosius, Ralf Petry
  • LIQUID-CRYSTAL DISPLAY
    Publication number: 20100272925
    Abstract: Disclosed are liquid-crystal (LC) media for use in LC displays of the PS (polymer stabilised) or PSA (polymer sustained alignment) type which contain a liquid-crystal (LC) mixture that contains one or more compounds of formula I
    Type: Application
    Filed: April 23, 2010
    Publication date: October 28, 2010
    Applicant: MERCK PATENT GESELLSCHAFT
    Inventors: Achim Goetz, Melanie Klasen-Memmer, Stephan Derow, Sabine Schoen, Peter Best
  • Liquid-crystalline medium
    Patent number: 7029731
    Abstract: The invention relates to a liquid-crystalline medium based on a mixture of polar compounds having positive dielectric anisotropy, characterized in that it comprises one or more compounds of the general formula I in which R, A1, Z1, Y and L are as defined in claim 1.
    Type: Grant
    Filed: August 6, 2003
    Date of Patent: April 18, 2006
    Assignee: Merck Patent GmbH
    Inventors: Kazuaki Tarumi, Brigitte Schuler, Eike Poetsch, Volker Reiffenrath, Yukiomi Tanaka
  • Phenyl-protein transferase inhibitors
    Patent number: 6333335
    Abstract: The present invention is directed to tetrahydro-imidazopyridinyl compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: December 25, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Christopher J. Dinsmore, Samuel L. Graham, Theresa M. Williams
  • Metal complexes
    Patent number: 10290819
    Abstract: The present invention relates to bisimidazolium salts, to novel mono- and biscarbenes derived therefrom, and to metal complexes which contain corresponding mono- and biscarbenes as ligands, to a process for the preparation of the bisimidazolium salts according to the invention, the mono- and biscarbenes according to the invention and to the metal complexes according to the invention, and to the use of the bisimidazolium salts according to the invention, the mono- and biscarbenes according to the invention and to the use of the metal complexes according to the invention.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: May 14, 2019
    Assignee: Merck Patent GmbH
    Inventors: Doris Kunz, Verena Gierz
  • Double Layer Liquid Crystal Device and Process of Manufacture
    Publication number: 20210096431
    Abstract: A double layer liquid crystal device comprises a first and a second layer with orthogonal or crossed alignment of the liquid crystal phase of the two layers, in which the first and second layer have first and second alignment aids comprised of a polymerized or polymerizable molecular compound. The layers are aligned by UV photoalignment and vertical self-alignment by the aid of suitable additives.
    Type: Application
    Filed: September 25, 2020
    Publication date: April 1, 2021
    Applicant: Merck Patent GmbH
    Inventors: Joseph SARGENT, Sarabjot KAUR, Simon SIEMIANOWSKI, Izumi SAITO
  • Novel cyclic Hexapeptide LHRH antagonists
    Patent number: 4659691
    Abstract: Novel peptides of the formula: ##STR1## where R.sup.1 through R.sup.8 are various radicals derived from L- and D- amino acids; having LHRH antagonist activity; useful in reducing fertility.Pharmaceutical compositions and methods for use in reducing fertility.
    Type: Grant
    Filed: February 8, 1985
    Date of Patent: April 21, 1987
    Assignee: Merck & Co., Inc.
    Inventors: Daniel F. Veber, Roger M. Freidinger
  • Eimeria acervulina 16S rDNA probes
    Patent number: 5298613
    Abstract: Unique species-specific Eimeria acervulina DNA probes comprising divergent DNA sequences are disclosed. The probes are complementary to a small subunit ribosomal RNA gene of Eimeria acervulina.
    Type: Grant
    Filed: May 12, 1992
    Date of Patent: March 29, 1994
    Assignee: Merck and Co., Inc.
    Inventors: Prasanta R. Chakraborty, Alex Elbrecht, Michael Dashkevicz, Scott D. Feighner, Paul A. Liberator, Helen Profous-Juchelka
  • Method of treating sweat-related conditions
    Patent number: 5730964
    Abstract: The instant invention involves methods of treating sweat related conditions with compounds that are 5.alpha.-reductase inhibitors. The 5.alpha.-reductase inhibitors may be administered alone or in combination with other active agents to treat conditions such as apocrine gland sweating, hyperhidrosis, and hydradenitis suppurativa.
    Type: Grant
    Filed: December 9, 1996
    Date of Patent: March 24, 1998
    Assignee: Merck & Co., Inc.
    Inventor: Joanne Waldstreicher
  • Antidiabetic agents based on aryl and heteroarylacetic acids
    Patent number: 6515015
    Abstract: The instant invention is concerned with aryl and heteroaryl acetic acid and oxyacetic acid compounds, which are useful as antidiabetic compounds. Compositions and methods for their use in the treatment of diabetes and related diseases and for lowering triglyceride levels are disclosed.
    Type: Grant
    Filed: October 24, 2000
    Date of Patent: February 4, 2003
    Assignee: Merck & Co. Inc.
    Inventors: Alan Adams, Derek Von Langen, Hiroo Koyama, Richard Tolman
  • Quinolin-2-one derivatives
    Patent number: 11174241
    Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in Claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: November 16, 2021
    Assignee: MERCK PATENT GMBH
    Inventors: Dieter Dorsch, Mathilde Muzerelle, Lars Burgdorf, Margarita Wucherer-Plietker, Paul Czodrowski, Christina Esdar, Christos Tsaklakidis
  • Tetrahydroquinolines for use as modulators of the mitotic motor protein Eg5
    Patent number: 8207345
    Abstract: Compounds of the formula (I), in which W, R, R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in Claim 1, can be employed, inter alia, for the treatment of tumors.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: June 26, 2012
    Assignee: Merck Patent GmbH
    Inventors: Kai Schiemann, David Bruge, Hans-Peter Buchstaller, Ulrich Emde, Dirk Finsinger, Christiane Amendt, Frank Zenke
  • Quinolin-2-one derivatives
    Patent number: 11186562
    Abstract: Compounds of the formula I in which X1, X2, X3, X4, R1, R2, R3, Q and Y have the meanings indicated in claim 1, are inhibitors of c-Kit kinase, and can be employed for the treatment of cancer.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: November 30, 2021
    Assignee: MERCK PATENT GMBH
    Inventors: Dieter Dorsch, Mathilde Muzerelle, Lars Burgdorf, Margarita Wucherer-Plietker, Paul Czodrowski, Christina Esdar, Christos Tsaklakidis
  • 2,3-dihydrobenzothiophene derivatives
    Patent number: 11174432
    Abstract: The present invention relates to 2,3-dihydrobenzothiophene derivatives of the general formula I In which the occurring groups and parameters have the meanings indicated in claim 1, to the use thereof in liquid-crystalline or mesogenic media, to liquid-crystalline or mesogenic media comprising these derivatives, and to electro-optical display elements containing these liquid-crystalline or mesogenic media.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: November 16, 2021
    Assignee: MERCK PATENT GMBH
    Inventors: Dmitry Ushakov, Helga Haas, Thorsten Vom Stein
  • AZAINDOLE DERIVATIVES
    Publication number: 20110207732
    Abstract: Compounds of the formula (I), in which X1, X2, X3, X4, R1, R2, R3 and R4 have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours.
    Type: Application
    Filed: September 24, 2009
    Publication date: August 25, 2011
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Timo Heinrich, Hannes Koolman
  • Process for preparing vat pigment dyes
    Patent number: 4806128
    Abstract: A process for preparing pigment dyes comprising reducing a colloidal dispersion of an impure dye to form a solution of the leucobase, introducing into this solution a finely divided substrate and, by adding an oxidizing agent, oxidizing the leucobase to form the vat dye, which thereby precipitates and deposits on the substrate.
    Type: Grant
    Filed: October 10, 1986
    Date of Patent: February 21, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventor: Juan M. Figueras
  • Liquid crystal medium
    Patent number: 6793983
    Abstract: The invention relates to a liquid-crystalline medium based on a mixture of polar compounds of positive dielectric anisotropy, characterized in that it comprises one or more compounds of the general formula I and at least one compound of the formula in which the substituents are as defined in claim 1.
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: September 21, 2004
    Assignee: Merck Patent GmbH
    Inventors: Michael Heckmeier, Brigitte Schuler, Kazuaki Tarumi, Peer Kirsch, Volker Reiffenrath
  • Gray interference pigment and process for producing the same
    Patent number: 5693134
    Abstract: An interference pigment comprising a platelet-shaped substrate coated with titanium dioxide and additionally oxidic compounds of copper and manganese, whereby the pigment powder color is dark gray.
    Type: Grant
    Filed: December 29, 1994
    Date of Patent: December 2, 1997
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventor: Alfred Stephens
  • REACTIVE MESOGEN FORMULATION WITH CONDUCTIVE ADDITIVE
    Publication number: 20170283699
    Abstract: The invention relates to a reactive mesogen (RM) formulation comprising a conductive additive, to a polymer film obtained thereof, and the use of the RM formulation and polymer film in optical or electrooptical components or devices, like optical retardation films for liquid crystal displays (LCDs).
    Type: Application
    Filed: June 22, 2017
    Publication date: October 5, 2017
    Applicant: Merck Patent GmbH
    Inventors: Graham SMITH, Owain Llyr PARRI, Vicki COOK, Georg BERNATZ, David WILKES, Jonathan Henry WILSON, Mark JAMES, Philip Edward MAY
  • Expression of fusion protein of HIV envelope and HBsAG
    Patent number: 5130247
    Abstract: The present invention relates to recombinant fusion polypeptides of HIV envelope and HBsAg, suitable as vaccines against AIDS and/or ARC and hepatitis, as well as immunogens for inducting antibodies for passive protection or treatment of AIDS and/or ARC.
    Type: Grant
    Filed: September 19, 1989
    Date of Patent: July 14, 1992
    Assignee: Merck & Co., Inc.
    Inventors: Peter J. Kniskern, Arpi Hagopian, Pamela Burke
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