Search Patents
  • Cab Molecules
    Publication number: 20080096810
    Abstract: The present invention relates to CAB molecules, ADEPT constructs directed against CEA, and their use in therapy.
    Type: Application
    Filed: April 12, 2005
    Publication date: April 24, 2008
    Inventors: Judith A. Fox, Fiona A. Harding, Rashid M. Harunur, Volker Schellenberger
  • Neuroprotective Compounds and Uses Thereof
    Publication number: 20090105159
    Abstract: The present invention relates to a neuroprotective compound consisting of the amino acid sequence DLHW.
    Type: Application
    Filed: May 3, 2007
    Publication date: April 23, 2009
    Applicant: EBEWE PHARMA GES.M.B.H. NFG.KG
    Inventors: Monika Hitzl, Herbert Mossler, Heinz Schnait
  • Novel proteins
    Publication number: 20030166044
    Abstract: Novel proteins are disclosed.
    Type: Application
    Filed: March 30, 2001
    Publication date: September 4, 2003
    Inventors: Kenneth Jacobs, John M. McCoy, Edward R. LaVallie, Lisa A. Collins-Racie, Cheryl Evans, David Merberg, Maurice Treacy
  • Long wavelength engineered fluorescent proteins
    Publication number: 20040014128
    Abstract: Engineered fluorescent proteins, nucleic acids encoding them and methods of use.
    Type: Application
    Filed: July 14, 2003
    Publication date: January 22, 2004
    Inventors: Rebekka M. Wachter, S. James Remington
  • Polypeptide
    Publication number: 20020137892
    Abstract: Isolated peptide transmitter-like receptor polypeptides, polynucleotides encoding such peptides, and methods of using such polypeptides in screening assays are described.
    Type: Application
    Filed: November 9, 2001
    Publication date: September 26, 2002
    Inventors: Steven M. Foord, Diane Michele Ignar
  • Genome Engineering
    Publication number: 20150031132
    Abstract: Methods of genome engineering in cells using a TALEN lacking repeat sequences or Cas9 is provided.
    Type: Application
    Filed: June 30, 2014
    Publication date: January 29, 2015
    Inventors: George M. CHURCH, Luhan YANG, Marc Guell CARGOL, Joyce Lichi YANG
  • MULTISPECIFIC ANTIBODIES
    Publication number: 20100322946
    Abstract: The invention provides multispecific antibodies and methods of making and using such antibodies.
    Type: Application
    Filed: September 1, 2009
    Publication date: December 23, 2010
    Applicant: Genentech, Inc.
    Inventors: Jenny M. Bostrom, Germaine Fuh
  • 5-oxoprolinase
    Patent number: 6120993
    Abstract: The present invention is directed to isolated nucleic acid molecules encoding mammalian 5-oxoprolinase (m 5-OPase). Expression vectors and host cells comprising the nucleic acid molecules are also provided, as well as methods for increasing or decreasing the expression of m 5-OPase in host cells. The invention further provides a method of screening a substance for the ability of the substance to modify m 5-OPase function, and a method for isolating other m 5-OPase molecules. DNA oligomers and antibodies specific for m 5-OPase are provided, each of which can be used to detect m 5-OPase in a sample.
    Type: Grant
    Filed: December 9, 1996
    Date of Patent: September 19, 2000
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Guo-jie Ye, Esther Breslow, Alton Meister, deceased, by Kenneth Meister, executor
  • COMPOSITIONS AND METHODS OF MAKING EMBRYONIC STEM CELLS
    Publication number: 20090170201
    Abstract: The invention relates to cell proliferation, cell differentiation, male infertility, male fertility and to compositions and methods involved therein.
    Type: Application
    Filed: May 22, 2008
    Publication date: July 2, 2009
    Applicant: VANDERBILT UNIVERSITY
    Inventors: Brigid L.M. Hogan, Guang-Quan Zhao
  • Biopsy methods and devices
    Patent number: 10539567
    Abstract: Disclosed are methods for detecting remnant cancer cells in a tissue sample.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: January 21, 2020
    Assignee: Indicator Systems International, Inc.
    Inventors: Gerald F. Swiss, John V. Fante, Robert M. Moriarty, Richard J. Pariza
  • Use of glycodendrimer reagents for inhibiting adhesion by microorganisms
    Publication number: 20040097720
    Abstract: The present invention is directed to glyodendrimeric proteases, composition with glycodendrimeric proteases and methods for inhibiting adhesion binding in microorganisms by contacting microorganisms with a glycodendrimeric protease or a composition with a glycodendrimeric protease. The invention may be used to treat patients in need of treatment.
    Type: Application
    Filed: April 16, 2003
    Publication date: May 20, 2004
    Inventors: Richard R. Bott, M. M. Cowan, Benjamin G. Davis, John Bryan Jones
  • Treating neural disease with tyrosine kinase inhibitors
    Patent number: 9474753
    Abstract: Provided herein are methods of treating or preventing a neurodegenerative disease, a myodegenerative disease or a prion disease in a subject comprising administering a tyrosine kinase inhibitor.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: October 25, 2016
    Assignee: GEORGETOWN UNIVERSITY
    Inventor: Charbel Moussa
  • MicroRNA signatures in human ovarian cancer
    Patent number: 9574239
    Abstract: Described herein are methods and compositions for the diagnosis, prognosis and treatment of ovarian cancer. Also described are methods of identifying anti-cancer agents.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: February 21, 2017
    Assignee: The Ohio State University Research Foundation
    Inventor: Carlo M. Croce
  • ANTI-ANGIOGENIC POLYPEPTIDES
    Publication number: 20090061510
    Abstract: Anti-angiogenic polypeptides A61 or p22 are disclosed. Also disclosed are methods of making the polypeptides and methods of treating subjects having angiogenic diseases or conditions.
    Type: Application
    Filed: July 31, 2008
    Publication date: March 5, 2009
    Inventors: David M. Waisman, Geeth Kassam, Mijung Kwon
  • METHOD AND COMPOSITIONS FOR MODULATING TH17 CELL DEVELOPMENT
    Publication number: 20100166784
    Abstract: The invention encompasses methods and compositions for modulating Th17 development.
    Type: Application
    Filed: December 30, 2009
    Publication date: July 1, 2010
    Applicant: THE WASHINGTON UNIVERSITY
    Inventors: Kenneth M. Murphy, Theresa Murphy, Kai Hildner, Barbara Schraml
  • RAGE FUSION PROTEINS
    Publication number: 20100291081
    Abstract: The present invention provides novel therapeutics and methods of treatment for diseases associated with activation of the advanced glycation endproducts receptor (RAGE).
    Type: Application
    Filed: June 13, 2008
    Publication date: November 18, 2010
    Applicant: Galactica Pharmaceuticals
    Inventors: Gregory T. Bleck, David M. Hilbert
  • GENERATION OF EPITHELIAL CELLS AND ORGAN TISSUE IN VIVO BY REPROGRAMMING AND USES THEREOF
    Publication number: 20150023934
    Abstract: The present invention encompasses methods for reprogramming fibroblast cells in culture, which are able to generate generic epithelial cells therefrom.
    Type: Application
    Filed: August 28, 2014
    Publication date: January 22, 2015
    Inventors: Flaminia IONAS, Michael M. SHEN
  • Protein-free gamete and embryo handling and culture media products
    Patent number: 8415094
    Abstract: This invention discloses a substantially protein-free cell culture solution for assisted reproductive technologies and methods of use thereof.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: April 9, 2013
    Inventor: Jaffar Ali bin M. Abdullah
  • Novel kallikrein gene
    Publication number: 20040058342
    Abstract: The invention relates to nucleic acid molecules. proteins encoded by such nucleic acid molecules: and use of the proteins and nucleic acid molecule.
    Type: Application
    Filed: August 1, 2003
    Publication date: March 25, 2004
    Inventors: George M Yousef, Eleftherios P Diamandis
  • SIGIRR DNA and polypeptides
    Patent number: 7446171
    Abstract: DNA encoding SIGIRR polypeptides and methods for using the encoded polypeptides are disclosed.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: November 4, 2008
    Assignee: Immunex Corporation
    Inventor: John Ernest Sims