Search Patents
  • Genome sharing
    Patent number: 10841312
    Abstract: Sharing data is disclosed. In some cases, sharing data includes receiving a request to share data from a first account to a second account, receiving an indication of a plurality of first account profiles associated with the first account to share with the second account, and establishing sharing from the plurality of first account profiles to the second account, wherein sharing comprises the second account having read access to a subset of nonpublic data associated with the plurality of first account profiles.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: November 17, 2020
    Assignee: 23andMe, Inc.
    Inventors: Brian Lee Hawthorne, Oleksiy Khomenko, Jeffrey Mellen, Marcela Miyazawa, Michael Polcari, Jack Tihon, Alexander Wong, Anne Wojcicki, Linda Avey
  • Genome sharing
    Patent number: 11683315
    Abstract: Sharing data is disclosed. In some cases, sharing data includes receiving a request to share data from a first account to a second account, receiving an indication of a plurality of first account profiles associated with the first account to share with the second account, and establishing sharing from the plurality of first account profiles to the second account, wherein sharing comprises the second account having read access to a subset of nonpublic data associated with the plurality of first account profiles.
    Type: Grant
    Filed: October 12, 2021
    Date of Patent: June 20, 2023
    Assignee: 23andMe, Inc.
    Inventors: Brian Lee Hawthorne, Oleksiy Khomenko, Jeffrey Mellen, Marcela Miyazawa, Michael Polcari, Jack Tihon, Alexander Wong, Anne Wojcicki, Linda Avey
  • Finding relatives in a database
    Patent number: 8463554
    Abstract: Determining relative relationship includes receiving recombinable deoxyribonucleic acid (DNA) information of a first user and recombinable DNA information of a second user, determining, based at least in part on the recombinable DNA information of the first user and recombinable DNA information of the second user, a predicted degree of relationship between the first user and the second user, and in the event that the expected degree of relationship between the first user and the second user at least meets the threshold, notifying at least the first user about a relative relationship with the second user.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: June 11, 2013
    Assignee: 23andMe, Inc.
    Inventors: Lawrence Hon, Serge Saxonov, Brian Thomas Naughton, Joanna Louise Mountain, Anne Wojcicki, Linda Avey
  • Computer implemented identification of modifiable attributes associated with phenotypic predispositions in a genetics platform
    Patent number: 11515047
    Abstract: A method, software, database and system for attribute partner identification and social network based attribute analysis are presented in which attribute profiles associated with individuals can be compared and potential partners identified. Connections can be formed within social networks based on analysis of genetic and non-genetic data. Degrees of attribute separation (genetic and non-genetic) can be utilized to analyze relationships and to identify individuals who might benefit from being connected.
    Type: Grant
    Filed: April 28, 2022
    Date of Patent: November 29, 2022
    Assignee: 23andMe, Inc.
    Inventors: Andrew Alexander Kenedy, Charles Anthony Eldering
  • Genome sharing
    Patent number: 11171962
    Abstract: Sharing data is disclosed. In some cases, sharing data includes receiving a request to share data from a first account to a second account, receiving an indication of a plurality of first account profiles associated with the first account to share with the second account, and establishing sharing from the plurality of first account profiles to the second account, wherein sharing comprises the second account having read access to a subset of nonpublic data associated with the plurality of first account profiles.
    Type: Grant
    Filed: April 28, 2021
    Date of Patent: November 9, 2021
    Assignee: 23andMe, Inc.
    Inventors: Brian Lee Hawthorne, Oleksiy Khomenko, Jeffrey Mellen, Marcela Miyazawa, Michael Polcari, Jack Tihon, Alexander Wong, Anne Wojcicki, Linda Avey
  • Computer implemented identification of treatments for predicted predispositions with clinician assistance
    Patent number: 11495360
    Abstract: A method, software, database and system for attribute partner identification and social network based attribute analysis are presented in which attribute profiles associated with individuals can be compared and potential partners identified. Connections can be formed within social networks based on analysis of genetic and non-genetic data. Degrees of attribute separation (genetic and non-genetic) can be utilized to analyze relationships and to identify individuals who might benefit from being connected.
    Type: Grant
    Filed: April 28, 2022
    Date of Patent: November 8, 2022
    Assignee: 23andMe, Inc.
    Inventors: Andrew Alexander Kenedy, Charles Anthony Eldering
  • Summarizing an aggregate contribution to a characteristic for an individual
    Patent number: 8510057
    Abstract: Summarizing an aggregate contribution to a characteristic for an individual is disclosed, including determining the characteristic to be evaluated, identifying one or more markers associated with the characteristic, retrieving the measurement of the individual for each of the one or more markers from a database of individuals' markers, retrieving a statistical factor that measures the association between the marker associated with the characteristic and the characteristic for each of the one or more markers from the marker database, and determining the aggregate contribution based at least in part on the retrieved statistical factors.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: August 13, 2013
    Assignee: 23andMe, Inc.
    Inventors: Linda Avey, Andro Rene Hsu, Oleksiy Khomenko, John Michael Macpherson, Joanna Louise Mountain, Brian Thomas Naughton, Serge Saxonov, Anne Wojcicki, Alexander Wong
  • Family inheritance
    Patent number: 10643740
    Abstract: Displaying a comparison of genetic data is disclosed, including receiving an indication of a first individual, receiving an indication of a second individual, retrieving the genotypic information for the first individual and the second individual, comparing the genotypic information of the first individual and the second individual, displaying an indication of the comparison of the genotypic information of the first individual and the second individual graphically. A first graphical symbol is used to display an indication of the genome regions for which the first individual and the second individual are identical. A second graphical symbol is used to display an indication of the genome regions for which the first individual and the second individual are half identical.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: May 5, 2020
    Assignee: 23andMe, Inc.
    Inventors: Linda Avey, Oleksiy Khomenko, Brian Thomas Naughton, Serge Saxonov, Anne Wojcicki, Alexander Wong
  • Method for analyzing and displaying genetic information between family members
    Patent number: 10790041
    Abstract: A technique of using collaborative family medical history (CFMH) to estimate disease risk includes establishing CFMH information of a user and a plurality of relatives of the user, the CFMH information including genetic information of at least some of the family members, genetic information of the user, or both. It further includes analyzing the CFMH information, including the genetic information. It further includes determining a potential risk condition of the user and a potential risk condition of at least a family member based on the CFMH information. It also includes outputting the potential risk condition of the user and the potential risk condition of the at least one family member.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: September 29, 2020
    Assignee: 23andMe, Inc.
    Inventors: John Michael Macpherson, Joanna Sim, Brian Thomas Naughton, Michael Polcari
  • ANTI-CD200R1 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20210371521
    Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human CD200R1 receptor protein (hu-CD200R1) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by hu-CD200R1. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CD200 binding to CD200R1.
    Type: Application
    Filed: May 28, 2021
    Publication date: December 2, 2021
    Applicant: 23andMe, Inc.
    Inventors: Yu CHEN, Jilean Beth FENAUX, Germaine FUH-KELLY, Yao-Ming HUANG, Wei-Jen CHUNG, Erik Edward KARRER, Cecilia LAY, Steven J. PITTS, Louise SCHARF
  • Window-based method for determining inherited segments
    Patent number: 11875879
    Abstract: Displaying a comparison of genetic data is disclosed, including receiving an indication of a first individual, receiving an indication of a second individual, retrieving the genotypic information for the first individual and the second individual, comparing the genotypic information of the first individual and the second individual, displaying an indication of the comparison of the genotypic information of the first individual and the second individual graphically. A first graphical symbol is used to display an indication of the genome regions for which the first individual and the second individual are identical. A second graphical symbol is used to display an indication of the genome regions for which the first individual and the second individual are half identical.
    Type: Grant
    Filed: May 17, 2023
    Date of Patent: January 16, 2024
    Assignee: 23andMe, Inc.
    Inventors: Linda Avey, Oleksiy Khomenko, Brian Thomas Naughton, Serge Saxonov, Anne Wojcicki, Alexander Wong
  • Identification of matrilineal or patrilineal relatives
    Patent number: 9116882
    Abstract: Determining relative relationships among a plurality of individuals, comprising: accessing user-specified genealogical information of at least some of the plurality of individuals and genetic information of recombinable deoxyribonucleic acids (DNAs) of at least some of the plurality of individuals; determining, using one or more computer processors and among the plurality of individuals, one or more related individuals who are relatives of a target individual, and information pertaining to the one or more related individuals, and presenting information pertaining to at least one of the one or more related individuals, including to present an indication of whether the at least one of the one or more related individuals is a matrilineal relative or a patrilineal relative of the target individual.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: August 25, 2015
    Assignee: 23andMe, Inc.
    Inventors: John Michael Macpherson, Michael Polcari, Brian Thomas Naughton
  • NOVEL USE
    Publication number: 20230220037
    Abstract: The present disclosure relates to an inhibitor of human TRPM3 for use in the treatment or prevention of migraine, including in subjects whose migraines are not responsive to CGRP inhibition or whose migraines are responsive to triptans. Combination therapies are also described. In other aspects, the present disclosure provides methods for identifying suitable patients, methods for identifying inhibitors of human TRPM3, cell lines and agonists for use in such methods and a method for measuring PACAP release.
    Type: Application
    Filed: July 13, 2022
    Publication date: July 13, 2023
    Applicants: GlaxoSmithKline Intellectual Property (No.3) Limited, 23andMe, Inc.
    Inventors: Janet Mary KUMAR, Colin Houston McPHEE, Adam Mohamed NAGUIB, Lea SAROV-BLAT, Claire Yvonne Marie TOWNSEND, Paul Bryan WREN, Clint Ernest YOUNG, Alexander George Steven PRESTON, David Andrew HALL
  • Methods and systems for determining and displaying pedigrees
    Patent number: 11514627
    Abstract: The disclosed embodiments concern methods, apparatus, systems and computer program products for determining and displaying pedigrees based on IBD data. Some implementations use a probabilistic relationship model to obtain various likelihoods of various potential relationships based on pairwise IBD data and pairwise age data. Some implementations build large pedigrees by combining smaller pedigrees. Some implementations display pedigree graphs with various features that are informative and easy to understand.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: November 29, 2022
    Assignee: 23andMe, Inc.
    Inventors: Ethan M. Jewett, Andrew C. Seaman, Kimberly F. McManus, William A. Freyman, Cordell T. Blakkan, Adam Auton, Joanna L. Mountain, Susan M. Furest, Rachel E. Lopatin, Hang Xu, Hilary M. Vance
  • Finding relatives in a database
    Patent number: 11049589
    Abstract: Determining relative relationships of people who share a common ancestor within at least a threshold number of generations includes: receiving recombinable deoxyribonucleic acid (DNA) sequence information of a first user and recombinable DNA sequence information of a plurality of users; processing, using one or more computer processors, the recombinable DNA sequence information of the plurality of users in parallel; determining, based at least in part on a result of processing the recombinable DNA information of the plurality of users in parallel, a predicted degree of relationship between the first user and a user among the plurality of users, the predicted degree of relative relationship corresponding to a number of generations within which the first user and the second user share a common ancestor.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: June 29, 2021
    Assignee: 23andMe, Inc.
    Inventors: Lawrence Hon, Serge Saxonov, Brian Thomas Naughton, Joanna Louise Mountain, Anne Wojcicki, Linda Avey
  • ANTI-CD200R1 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20240018239
    Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human CD200R1 receptor protein (hu-CD200R1) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by hu-CD200R1. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CD200 binding to CD200R1.
    Type: Application
    Filed: August 24, 2023
    Publication date: January 18, 2024
    Applicant: 23andMe, Inc.
    Inventors: Yu CHEN, Jilean Beth FENAUX, Germaine FUH-KELLY, Yao-Ming HUANG, Wei-Jen CHUNG, Erik KARRER, Cecilia LAY, Steven J. PITTS, Louise SCHARF
  • Finding relatives in a database
    Patent number: 11322227
    Abstract: Determining relative relationships of people who share a common ancestor within at least a threshold number of generations includes: receiving recombinable deoxyribonucleic acid (DNA) sequence information of a first user and recombinable DNA sequence information of a plurality of users; processing, using one or more computer processors, the recombinable DNA sequence information of the plurality of users in parallel; determining, based at least in part on a result of processing the recombinable DNA information of the plurality of users in parallel, a predicted degree of relationship between the first user and a user among the plurality of users, the predicted degree of relative relationship corresponding to a number of generations within which the first user and the second user share a common ancestor.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: May 3, 2022
    Assignee: 23andMe, Inc.
    Inventors: Lawrence Hon, Serge Saxonov, Brian Thomas Naughton, Joanna Louise Mountain, Anne Wojcicki, Linda Avey
  • Finding relatives in a database
    Patent number: 11657902
    Abstract: Determining relative relationships of people who share a common ancestor within at least a threshold number of generations includes: receiving recombinable deoxyribonucleic acid (DNA) sequence information of a first user and recombinable DNA sequence information of a plurality of users; processing, using one or more computer processors, the recombinable DNA sequence information of the plurality of users in parallel; determining, based at least in part on a result of processing the recombinable DNA information of the plurality of users in parallel, a predicted degree of relationship between the first user and a user among the plurality of users, the predicted degree of relative relationship corresponding to a number of generations within which the first user and the second user share a common ancestor.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: May 23, 2023
    Assignee: 23andMe, Inc.
    Inventors: Lawrence Hon, Serge Saxonov, Brian Thomas Naughton, Joanna Louise Mountain, Anne Wojcicki, Linda Avey
  • Finding relatives in a database
    Patent number: 11508461
    Abstract: Determining relative relationships of people who share a common ancestor within at least a threshold number of generations includes: receiving recombinable deoxyribonucleic acid (DNA) sequence information of a first user and recombinable DNA sequence information of a plurality of users; processing, using one or more computer processors, the recombinable DNA sequence information of the plurality of users in parallel; determining, based at least in part on a result of processing the recombinable DNA information of the plurality of users in parallel, a predicted degree of relationship between the first user and a user among the plurality of users, the predicted degree of relative relationship corresponding to a number of generations within which the first user and the second user share a common ancestor.
    Type: Grant
    Filed: January 14, 2022
    Date of Patent: November 22, 2022
    Assignee: 23andMe, Inc.
    Inventors: Lawrence Hon, Serge Saxonov, Brian Thomas Naughton, Joanna Louise Mountain, Anne Wojcicki, Linda Avey
  • Finding relatives in a database
    Patent number: 11031101
    Abstract: Determining relative relationships of people who share a common ancestor within at least a threshold number of generations includes: receiving recombinable deoxyribonucleic acid (DNA) sequence information of a first user and recombinable DNA sequence information of a plurality of users; processing, using one or more computer processors, the recombinable DNA sequence information of the plurality of users in parallel; determining, based at least in part on a result of processing the recombinable DNA information of the plurality of users in parallel, a predicted degree of relationship between the first user and a user among the plurality of users, the predicted degree of relative relationship corresponding to a number of generations within which the first user and the second user share a common ancestor.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: June 8, 2021
    Assignee: 23andMe, Inc.
    Inventors: Lawrence Hon, Serge Saxonov, Brian Thomas Naughton, Joanna Louise Mountain, Anne Wojcicki, Linda Avey
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