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  • Cellulose hydrogel compositions and contact lenses for corneal applications
    Patent number: 9175153
    Abstract: The present invention provides cellulose hydrogels having one or more of the following properties: high water content, high transparency, high oxygen permeability, high biocompatibility, high tensile strength and desirable thermal stability. The present invention further provides a process for preparing a cellulose hydrogel comprising (i) a step of activating cellulose, in which the activating step comprises contacting the cellulose with a solvent to activate the cellulose for a time duration from about 2 hours to about 30 hours; (ii) substantially dissolving the activated cellulose to form a solution; and (iii) gelling the solution to form a gel, in which the gelling step comprises allowing the solution to gel in an environment comprising a relative humidity from about 30% to about 80% at 35° C.
    Type: Grant
    Filed: September 11, 2014
    Date of Patent: November 3, 2015
    Assignee: The Johns Hopkins University
    Inventors: Morgana M. Trexler, Jenna L. Graham, Jennifer L. Breidenich, Jeffrey P. Maranchi, Julia B. Patrone, Marcia W. Patchan, Jennifer H. Elisseeff, Xiomara Calderon-Colon
  • Cellulose hydrogel compositions and contact lenses for corneal applications
    Patent number: 9441080
    Abstract: The present invention provides cellulose hydrogels having one or more of the following properties: high water content, high transparency, high oxygen permeability, high biocompatibility, high tensile strength and desirable thermal stability. The present invention further provides a process for preparing a cellulose hydrogel comprising (i) a step of activating cellulose, in which the activating step comprises contacting the cellulose with a solvent to activate the cellulose for a time duration from about 2 hours to about 30 hours; (ii) substantially dissolving the activated cellulose to form a solution; and (iii) gelling the solution to form a gel, in which the gelling step comprises allowing the solution to gel in an environment comprising a relative humidity from about 30% to about 80% at 35° C.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: September 13, 2016
    Assignee: The Johns Hopkins University
    Inventors: Morgana M. Trexler, Jeffrey P. Maranchi, Jennifer L. Breidenich, Xiomara Calderon-Colon, Julia B. Patrone, Jennifer H. Elisseeff, Marcia W. Patchan, Jenna L. Graham, Oliver D. Schein
  • Drying device for producing small quantities of controlled particle size catalysts which are appropriate for use in fluidized bed operations such as fluid catalytic cracking
    Patent number: 7867937
    Abstract: Catalysts for experimentation are produced having a controlled matrix pore structure. The manufacturing process utilizes tape casting in the drying procedure in which a catalyst slurry is cast on a substrate and dried at a temperature of between about 50° C. to 200° C. for a period of time of about 0.1 to 1.0 hour. The dried catalyst particles can be removed from the substrate by several techniques, including scraping, burning, and deforming the substrate material. The resulting catalytic particles can be produced in an amount of about ca. 3 g to 300 g from slurries with volumes between 5 cc to 500 cc, which are suitable for small scale FCC reactors and for high throughput experimentation.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: January 11, 2011
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: William A. Wachter, Jeffrey T. Elks, Brenda A. Raich, Theodore E. Datz, Mary T. Van Nostrand, Gordon F. Stuntz, David O. Marler, Nicholas Rollman
  • Process of removing calcium and obtaining sulfate salts from an aqueous sugar solution
    Patent number: 8273181
    Abstract: The present invention provides a process for obtaining a product stream comprising one or more sulfate salts of potassium, sodium or ammonium from a sugar stream resulting from [processing a lignocellulosic feedstock, said sugar stream which includes calcium sulfate and one or more of these sulfate salts. The process comprises (i) treating the sugar stream to remove calcium, thereby producing a sugar stream containing substantially no calcium, and obtaining a salt stream comprising a calcium salt; (ii) choosing a feed stream that is either (a) a clarified salt stream derived from the salt stream of step (i) after removal of calcium therefrom; or (b) the sugar stream containing substantially no calcium that is produced in step (i); (iii) introducing the feed stream chosen in step (ii) to an ion exchange bed; and (iv) regenerating the ion exchange resin bed of step (iii) with sulfuric acid to produce the product stream.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: September 25, 2012
    Assignee: Iogen Energy Corporation
    Inventors: Brian E. Foody, Jeffrey S. Tolan
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