Abstract: Provided herein are compounds according to Formulas (I) or (II) and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various methods, including treating cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease, osteoarthritis, idiopathic pulmonary fibrosis and neurological conditions/disorders/diseases.

Abstract: A method and apparatus for assembling a complex product in a parallel process system wherein a collection of components are provided for assembling the complex product. The present invention involves transferring the collection of components to one of a plurality of similar computerized assembly cells through the use of a transport system. The collection of components is automatically assembled into the complex product through the use of the computerized assembly cells. The complex product is then transferred from one of the assembly cells to a computerized test cell, where the complex product is tested to ensure for the proper dimensioning and functioning of the complex product. The complex product is then transferred from the test cell via the transport system to either a part reject area or conveyor, if the product is defective, or to an automatic dunnage load or part return system, if the product is not defective.

Abstract: Systems and methods are provided to generate information indicative of the opportunity to provide offers to affluent account holders, based on transaction data recording the transactions in the accounts of the account holders. The opportunity information may not be indicative of the actual overall spending level of the account holders. The opportunity information is generated based on rankings of the respective accounts based on spending characteristics in a plurality of merchant categories, such as international travel, dining out, specialty retail, etc.

Abstract: One or more computer implemented systems for continuously processing used oils are provided. The system can include a feedstock tank containing feedstock. The feedstock tank can have a sparger and a level sensor. The feedstock tank can be in fluid communication with a first pump, a first filter, a heater, a second filter, first flow meter, a primary nozzle, a secondary nozzle, a motionless inline static mixer, and a first reactor.

Abstract: A method of imparting hair strand effects may include identifying each of a plurality of hair strands to which to apply a hair strand effect product independently and individually, the plurality of hair strands associated with an illustration of at least one type of hair strand effects and one of a plurality of hair styles, and applying the product to each of the plurality of hair strands independently and individually subsequent to identifying the plurality of hair strands. In the alternative or in combination, a hair instruction guide may be consulted, the guide having at least one strand size associated with one of the plurality of types of hair strand effects, and a strand of hair may be identified according to the at least one strand size. A system for creating a hair strand effect may include a hair strand effect product and such a hair instruction guide.

Abstract: Compounds having the formula I wherein Z, Z1 Z2 Z, R3a, R3b and Rb and as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.

Abstract: The present invention discloses ?-diketones, ?-diketones or ?-hydroxyketones or analogs thereof, that activate Wnt/?-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.

Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases due to mutations in Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: An assembly configured for attachment to a media drive can include a base with a hinge end and a hinge axis and a handle with a hinge end, a locking tab and a swing end where the handle is configured for a locked orientation with respect to the base with the hinge end of the base extending outwardly beyond the hinge end of the handle and configured for an unlocked orientation with respect to the base with the hinge end of the base extending outwardly beyond the hinge end of the handle. Various other apparatuses, systems, methods, etc., are also disclosed.

Abstract: A user of a personal computing device may identify multiple travel items of interest displayed for purchase by a network-based travel service. However, the user may not desire to purchase the travel items in a single purchase. Upon making a travel purchase that includes a first travel item that does not include a second travel item corresponding to the first travel item, the user may employ the network travel package service to search for second travel items corresponding to the first travel item, select from discounted travel packages including the first travel item and second travel items returned from the search, and purchase a discounted travel package. Beneficially, multiple travel items may be purchased separately while obtaining a package discount as compared to the stand-alone price of the travel items.

Abstract: A fluid analyzing system wherein an electronic control module is coupled with an asset and a telematics device. The electronic control module initiates the acquisition of a sample of an asset's fluid and analyzes the sample in response to an analysis trigger. An asset management system located remotely from the asset and telematics device receives the results of the fluid analysis wirelessly via the telematics device.

Abstract: A method and apparatus for over-the-air provisioning of authentication credentials at an access device via a first access system, wherein the authentication credentials are for a second access system lacking an over-the-air provisioning procedure. For example, the second access system may be a 3GPP system using AKA authentication methods. The first access system may be CDMA, using an OTASP or IOTA procedure. Provisioning the authentication credentials may include provisioning any of a 3GPP AKA authentication root key (K), AKA authentication related parameters, an AKA authentication algorithm to be used in the 3GPP authentication, or authentication algorithm customization parameters.

Abstract: A process for additive manufacturing of a resorbable implant to be implanted into a patient includes providing a biocompatible resin including a liquid light-polymerizable material that is resorbable after polymerization and an initiator. The process further includes actuating an additive manufacturing apparatus to expose an amount of the biocompatible resin to light to at least partially cure the exposed amount of biocompatible resin to form a layer of the resorbable implant and actuating the additive manufacturing apparatus to expose at least some additional amount of biocompatible resin to light to at least partially cure the exposed additional amount of biocompatible resin to form an additional layer of the resorbable implant and to at least partially overcure previously cured layers to cause at least some interlayer binding between the previously cured layers and the additional layer.

Abstract: This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.

Abstract: Provided herein are compounds according to Formula I and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various methods, including treating cancers such as colon, ovarian, pancreatic, breast, liver, prostate and hematologic cancers:

Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases due to mutations in Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: Provided herein are compounds according to Formulas (I) or (II) and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various methods, including treating cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease, osteoarthritis, idiopathic pulmonary fibrosis and neurological conditions/disorders/diseases.

Abstract: A system and method for display of multiple data sets related to building systems is provided. A first building system includes a first sensor that generates first operating data corresponding to the first building system. A second building system includes a second sensor that generates second operating data corresponding to the second building system. A data server stores the first operating data and the second operating data. A user terminal accesses the first operating data and the second operating data, receives user input selecting the first operating data and the second operating data for display, and displays the first operating data and the second operating data together in a graphical display.

Abstract: An aluminum tubular beam is assembled to a steel box frame rail with a steel sleeve. The sleeve is connected by a crimp joint or by a hem flange to the tubular beam. The steel sleeve may be effectively welded to the steel box frame rail to which it is assembled. An adhesive may be provided between the sleeve and the beam.

Abstract: Techniques are described to calibrate the downlink and uplink channels to account for differences in the frequency responses of the transmit and receive chains at an access point and a user terminal. In one method, pilots are transmitted on the downlink and uplink channels and used to derive estimates of the downlink and uplink channel responses, respectively. Correction factors for the access point and correction factors for the user terminal are determined based on (e.g., by performing matrix-ratio computation or minimum mean square error (MMSE) computation on) the downlink and uplink channel response estimates. The correction factors for the access point and the correction factors for the user terminal are used to obtain a calibrated downlink channel and a calibrated uplink channel, which are transpose of one another. The calibration may be performed in real time based on over-the-air transmission.