Abstract: A system provides for lateral translational corrective force(s) and/or derotational corrective force(s) on a spinal column and includes highly adaptive hardware for connecting the system to the spinal column, where the hardware facilitates a more natural range of motion within pre-selected limits and application of such lateral translational and/or derotational corrective force(s). The upper and lower vertebral segments retain freedom of movement while an apical or restricted segment is restricted from relative vertebral movement. A central segment controls primary rod roll while the rod is free to change in pitch, yaw and roll at the upper (superior) and lower (inferior) segments.
Type:
Grant
Filed:
October 17, 2013
Date of Patent:
February 21, 2017
Assignee:
K2M, Inc.
Inventors:
Matthew S. Stenulson, Thomas J. Gisel, John F. Otte, Steven J. Seme
Abstract: An operating method of a first device (100) in a wireless communication system is presented. The method comprises the steps of: determining whether DM-RS are mapped to a first symbol or a second symbol of symbols associated with a PSBCH; determining whether a first payload or a second payload is mapped to the first symbol or the second symbol; generating a sidelink synchronization signal block (S-SSB); and transmitting the S-SSB to a second device (200).
Abstract: A synthetic DNA vaccine against SARS-CoV-2 infection comprises a codon-optimized coding sequence for optimal mammalian expression of a pSARS2 spike glycoprotein (pSARS2-S). The signal peptide may be replaced with the signal peptide from the human IgG2 heavy chain. Systemic S1-specific IgG antibodies and neutralizing antibodies (nAbs) were significantly induced in mice at 2 weeks-post three injections with 100 ?g of the pSARS2-S vaccine via intramuscular (IM) needle injection. IM immunization induced Th1-skewed and long-lasting IgG response in BALB/c mice. Immunogenicity and induction of nAbs were enhanced with a needle-free delivery system, wherein two doses were sufficient to elicit significant levels of systemic S1-specific IgG antibodies and nAbs via IM or intradermal immunization.
Type:
Application
Filed:
March 16, 2021
Publication date:
September 22, 2022
Inventors:
Anwar M. Hashem, Mohamed A. Alfaleh, Turki S. Abujamel, Sawsan S. Alamri, Abdullah Algaissi, Khalid A. Alluhaybi
Abstract: An indicator device useful for detecting H.sub.2 S is disclosed. This detector utilizes a polymer having a permeation constant of at least 5.times.10.sup.-9 cm.sup.3 H.sub.2 S.multidot.cm thickness/(cm.sup.2 area.multidot.sec.multidot.cm Hg) with an incorporated lead containing compound at concentration levels of at least 10 weight percent. These compositions are useful for detecting hydrogen sulfide in concentrations as low as approximately 10 parts per billion by volume, or concentrations of approximately 1 part per million in relatively short periods, e.g., five minutes, and are utilizable for quantitative measurements of H.sub.2 S concentration.
Type:
Grant
Filed:
August 15, 1979
Date of Patent:
July 21, 1981
Assignee:
Bell Telephone Laboratories, Incorporated
Abstract: Disclosed herein are methods and compositions for modulating the levels and/or activity of S-nitrosoglutathione reductase (GSNOR) in vivo or in vitro. Specifically disclosed are GSNOR deletion constructs, host cells and non-human mammals comprising GSNOR deletions, and methods of screening employing GSNOR deletion mutants. Also specifically disclosed are reagents and procedures for measuring, monitoring, or altering GSNOR levels or activity (as well as nitric oxide and S-nitrosothiol levels) in connection with various medical conditions.
Abstract: A method of estimating log-likelihood ratios for first and second streams of samples of a received S-FSK signal demodulated using first and second carriers includes estimating channel and noise parameters associated with first and second transmitted values for the first and second streams of samples obtained from the received S-FSK modulated signal. Current signal-to-noise ratios are estimated for current samples of the first and second streams of samples obtained from the received S-FSK modulated signal using the channel and noise parameters. The estimated current signal-to-noise ratios are compared with values of a discrete ordered set and respective pairs of consecutive values of the discrete ordered set between which the estimated current signal-to-noise ratios are comprised are identified. Log-likelihood ratios are estimated for the current samples of the first and second streams.
Abstract: Photovoltaic devices based on an Ag2ZnSn(S,Se)4 (AZTSSe) absorber and techniques for formation thereof are provided. In one aspect, a method for forming a photovoltaic device includes the steps of: coating a substrate with a conductive layer; contacting the substrate with an Ag source, a Zn source, a Sn source, and at least one of a S source and a Se source under conditions sufficient to form an absorber layer on the conductive layer having Ag, Zn, Sn, and at least one of S and Se; and annealing the absorber layer. Methods of doping the AZTSSe are provided. A photovoltaic device is also provided.
Type:
Grant
Filed:
July 5, 2018
Date of Patent:
June 11, 2019
Assignee:
International Business Machines Corporation
Inventors:
Talia S. Gershon, Supratik Guha, Oki Gunawan, Richard A. Haight, Yun Seog Lee
Abstract: The present invention provides an oncolytic virus comprising nucleotide sequence(s) encoding one or more immune checkpoint modulator(s). It also concerns a pharmaceutical composition comprising effective amount of said oncolytic virus and, eventually, a pharmaceutically acceptable vehicle and its use for treating proliferative diseases such as cancers.
Type:
Grant
Filed:
July 16, 2015
Date of Patent:
February 11, 2020
Assignee:
Transgene S.A.
Inventors:
Nathalie Silvestre, Michel Geist, Karola Rittner, Jean-Baptiste Marchand, Christine Thioudellet
Abstract: Certain example embodiments relate to capacitive touch panels. First and second glass substrates are substantially parallel and spaced apart from one another. At least one multi-layer transparent conductive coating (TCC) is patterned into electrodes and located between the first and second substrates. The TCC(s) include(s) at least one conductive layer including silver, a dielectric layer including zinc oxide under and directly contacting the conductive layer including silver, and a dielectric layer(s) including tin oxide or silicon nitride over the conductive layer including silver. Processing circuitry electrically connects to the electrodes and measures an aspect of the electrodes' capacitance. A laminate material is located between the first and second glass substrates. The TCC(s), when blanket deposited, may have a visible transmission of at least 88%, a sheet resistances of no more than 10 ohms per square, and a haze of no more than 0.5%. Mutual and self-capacitance designs are disclosed.
Type:
Grant
Filed:
July 21, 2016
Date of Patent:
August 15, 2017
Assignee:
Guardian Industries Corp.
Inventors:
Vijayen S. Veerasamy, Jason Blush, Eric W. Akkashian, Willem Den Boer, Alexey Krasnov
Abstract: A single antenna assembly receives both direct broadcast satellite signals (DBS) and terrestrial broadcast signals, such as local VHF and UHF television channel broadcasts. The assembly includes an electromagnetic signal reflector for reflecting and focusing electromagnetic signals in a first band of frequencies, such as microwave signals for DBS. Incorporated in the reflector is an antenna for receiving electromagnetic signals in a second band of frequencies.
Abstract: The present invention relates to aldehyde, oxime and phenylhydrazone derivatives of the novel antibiotic substance, acid S, produced by the organism Polyangium cellulosum var. fulvum (ATCC No. 25532) and to processes for their preparation. The aldehyde, oxime and phenylhydrazone derivatives of acid S of this invention are useful as antifungal agents.
Type:
Grant
Filed:
February 4, 1977
Date of Patent:
July 4, 1978
Assignee:
Warner-Lambert Company
Inventors:
David T. Connor, Samuel M. Ringel, Maximillian Von Strandtmann
Abstract: Process for transforming (benzoyl-3-phenyl)-2-propionic-R(-) acid into an S(+) isomer through the action of a base either in situ during the splitting of racemic ketoprofen or on the crystallization mother liquor of a (benzoyl-3-phenyl)-2-propionic-S(+) acid salt.
Type:
Grant
Filed:
March 16, 1994
Date of Patent:
June 20, 1995
Assignee:
Rhone-Poulenc Rorer, S.A.
Inventors:
Claude Bertrand, Elie Fouque, Isidore Le Fur, Jean-Paul Richard