Search Patents
  • Cannabidiol (CBD) Formulation Including Caprylic Acid
    Publication number: 20200022924
    Abstract: A cannabinoid composition for enabling nearly simultaneous sublingual delivery of at least one cannabinoid, and an anti-fungal agent to the digestive tract of a subject. The composition includes cannabidiol, caprylic acid, lecithin, and at least one terpene. The ratio of cannabidiol to caprylic acid is between 10:1 and 25:1 on a weight to weight (w:w) basis. Preferably, the lecithin is liquid soy lecithin, the cannabidiol is an isolate having at least 95% purity, and the at least one terpene is engineered to have a therapeutic entourage effect in combination with the at least one cannabinoid in vivo.
    Type: Application
    Filed: July 19, 2018
    Publication date: January 23, 2020
    Inventors: Cody D. Freeze, Allison N. Freeze
  • USE OF THE PHYTOCANNABINOID CANNABIDIOL (CBD) IN COMBINATION WITH A STANDARD ANTI-EPILEPTIC DRUG (SAED) IN THE TREATMENT OF EPILEPSY
    Publication number: 20220395470
    Abstract: The invention relates to the use of cannabidiol (CBD), at a dose of greater than 300 mg/day, in combination with a standard anti-epileptic drug (SAED) which acts via sodium or calcium channels, for use in the treatment of epilepsy. The SAED is preferably one which •modities low-threshold or transient neuronal calcium currents, or •reduces high-frequency neuronal firing and sodium-dependent action potentials and enhances GABA effects. Preferred SAEDs are ethosuximide and valproate.
    Type: Application
    Filed: January 26, 2022
    Publication date: December 15, 2022
    Inventors: Benjamin WHALLEY, Claire Williams, Gary Stephens
  • SYSTEMS AND METHODS FOR CANNABIS CBD EXTRACTION
    Publication number: 20230034720
    Abstract: Systems and methods for extracting a compound of interest from plant material, such as a cannabidiol (CBD) from cannabis, are provided. Particularly, the disclosed systems and methods utilize a crude oil to separate water and impurities including fats, sugars, resin glues, chlorophyll, and proteins prior to preparation of a CBD distillate. The systems and methods are operable to remove the impurities from the crude oil with a brine solution and at least one acid prior to distillation. The systems and methods are operable with conventional solvents containing between about 5 wt % and about 8 wt % water.
    Type: Application
    Filed: August 9, 2022
    Publication date: February 2, 2023
    Inventor: Minyu Shi
  • METHODS FOR CONVERTING CBD TO TETRAHYDROCANNABINOLS
    Publication number: 20240018116
    Abstract: This disclosure provides a method for converting CBD to a tetrahydrocannabinol featuring the use of cheap and non-toxic aluminum isopropoxide as a catalyst. The method comprises (a) providing a reaction mixture comprising a catalyst in an organic solvent, wherein the catalyst comprises aluminum isopropoxide; (b) adding a reagent comprising CBD to the reaction mixture; (c) mixing the reaction mixture and allowing a reaction for converting CBD to a tetrahydrocannabinol to occur for a predetermine period of time; (d) removing the catalyst by filtration upon the completion of the reaction; (e) removing the organic solvent; and (f) eluting the tetrahydrocannabinol from the organic phase.
    Type: Application
    Filed: September 26, 2023
    Publication date: January 18, 2024
    Inventor: Ahmad Dehestani
  • METHOD FOR INCREASING THC/CBD CONTENT IN A CANNABIS PRODUCT
    Publication number: 20220008493
    Abstract: A method for increasing THC or CBD content, or both, in a cannabis product. A profile is selected with at least two components, one of which is a wet extract, and combining them into a combined cannabis product. The combined cannabis product is freeze-dried, resulting in at least one wet extract component drawing inward and away from the surface. A second portion of at least one component containing THC or CBD, or both can then be added to the surface, enhancing the amount of THC and/or CBD content of the product.
    Type: Application
    Filed: September 26, 2021
    Publication date: January 13, 2022
    Applicant: Byrn Brands, LLC
    Inventors: Danen Thibodeau, Bill Plifka
  • Process and composition for preparing a lignocellulose-based product, and the product obtained by the process
    Publication number: 20050257905
    Abstract: A process for the manufacture of a lignocellulose product, the process comprising the step of mixing in a reaction medium (i) a phenolic polymer being substituted with a phenolic hydroxy group; (ii) a lignocellulose containing material having immobilized to a cellulosic fraction thereof a fusion polypeptide, the fusion polypeptide including an enzyme being capable of catalyzing the oxidation of phenolic groups and a cellulose binding peptide; and (iii) an oxidizing agent. A composition of matter for use in the process and a lignocellulose product obtainable by the process are also disclosed.
    Type: Application
    Filed: July 29, 2005
    Publication date: November 24, 2005
    Applicants: Yissum Research Development Company of the Hebrew University, CBD Technologies Ltd.
    Inventor: Oded Shoseyov
  • Chemical bath deposition (CBD) apparatus
    Patent number: 9249507
    Abstract: A chemical bath deposition (CBD) apparatus includes a first cap, a second cap, and a solution input/output device. The second cap is arranged corresponding to the first cap so as to form a deposition space. The solution input/output device is located in the first cap so as to feed a solution into/out of the deposition space. The position of the solution input/output device is fixed, or the solution input/output device is movable in the deposition space.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: February 2, 2016
    Assignee: Industrial Technology Research Institute
    Inventors: Wei-Tse Hsu, Tung-Po Hsieh, Song-Yeu Tsai
  • METHODS FOR CONVERTING CBD TO TETRAHYDROCANNABINOLS
    Publication number: 20210221783
    Abstract: This disclosure provides a method for converting CBD to a tetrahydrocannabinol featuring the use of cheap and non-toxic aluminum isopropoxide as a catalyst. The method comprises (a) providing a reaction mixture comprising a catalyst in an organic solvent, wherein the catalyst comprises aluminum isopropoxide; (b) adding a reagent comprising CBD to the reaction mixture; (c) mixing the reaction mixture and allowing a reaction for converting CBD to a tetrahydrocannabinol to occur for a predetermine period of time; (d) removing the catalyst by filtration upon the completion of the reaction; (e) removing the organic solvent; and (f) eluting the tetrahydrocannabinol from the organic phase.
    Type: Application
    Filed: October 21, 2020
    Publication date: July 22, 2021
    Applicant: Cannacraft, Inc.
    Inventor: Ahmad Dehestani
  • Lotion and tinctures containing CBD oil including preparation and use thereof
    Patent number: 11559499
    Abstract: Here is presented a novel formulation of a topical treatment containing cannabidiol (CBD), as well as shea butter, cocoa butter coconut oil, aloe vera, body butter, lavender, lemongrass and tangerine. Such formulation may be applied to the skin in a variety of applications. The formulations are made with nearly no THC. Formulations include massage oil, pain relief cream, gardener's relief cream, warming cream, hand and body lotion grip, massage lotion glide and a gardener's relief oil.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: January 24, 2023
    Inventors: Greg Lutovsky, Alexa Blanken
  • Complex Fungally Fermented CBD Oral Dosage Forms
    Publication number: 20210106635
    Abstract: The present invention is a cannabidiol oral dosage form including predominantly or exclusively hemp pomace that has been co-fermented with a complex fungi, compounded as a tablet or formulated within a capsule. The dosage forms contain dietary fiber, important to activity as the desired delivery system, having a ratio of at least one part soluble dietary fiber to 30 parts insoluble dietary fiber, and delivers desirable/non hallucinogenic cannabinoids (CBD, CBG) in a ratio of 60:1 up to 120:1 to hallucinogenic cannabinoids (THC).
    Type: Application
    Filed: February 28, 2020
    Publication date: April 15, 2021
    Applicant: beyond hemp, llc
    Inventor: Jordan Seth Rubin
  • Methods and systems to measure cannabidiol (CBD)
    Patent number: 11867706
    Abstract: The methods and systems may include LC-MS/MS. For example the method may include obtaining MS/MS data for a predetermined MS/MS transition for THC and/or at least one THC metabolite and CBD and/or at least one CBD metabolite, and determining a ratio of the amount of the CBD and/or at least one CBD metabolite to the amount of the THC and/or at least one THC metabolite for the biological sample. In certain embodiments, the methods and/or systems are used to distinguish CBD from THC use in a subject.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: January 9, 2024
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Gregory C. Janis, Melissa M. Goggin
  • METHODS FOR CONVERTING CBD, CBDA AND ANALOGS THEREOF INTO DELTA8-THC, DELTA8-THCA AND ANALOGS THEREOF
    Publication number: 20220106283
    Abstract: Disclosed herein are methods for converting cannabidiol, cannabidiolic acid and analogs thereof into ?8-tetrahydrocannabinol, ?8-tetrahydrocannabinolic acid and analogs thereof. In particular, there is provided a method for converting a compound of Formula (I) as defined herein into a compound of Formula (II) as defined herein, the method comprising heating the compound of Formula (I) and a Lewis acidic heterogeneous reagent in an aprotic-solvent system to provide a compound of Formula (II), wherein the Lewis-acidic heterogeneous reagent is acidic alumina.
    Type: Application
    Filed: December 16, 2021
    Publication date: April 7, 2022
    Inventors: Christopher ADAIR, Roger GALLANT, Ben GEILING, Mohammadmehdi HAGHDOOST MANJILI
  • FABRICATION OF PBSE NANOSTRUCTURES BY EMPLOYING CHEMICAL BATH DEPOSITION (CBD) FOR PHOTONICS APPLICATIONS
    Publication number: 20230160099
    Abstract: Methods and systems are provided for a homogenous, single crystal, electrically conductive, and narrow bandgap PbSe nanostructure is synthesized using a chemical bath deposition on, for example, quartz substrates, and includes a tunable iodine doping process to select the size and/or shape of the nanostructures. The single crystalline PbSe nanostructure can be exposed following an isolation process (e.g., etching process), and the concentration and/or distribution of iodine across multiple PbSe nanostructures (e.g., on a quartz substrate) can be adjusted during post processing steps, including heat treatments.
    Type: Application
    Filed: November 16, 2022
    Publication date: May 25, 2023
    Inventors: Richard S. Kim, Jeung Hun Park
  • Method of Extracting CBD, THC, and other Compounds from Cannabis using Controlled Cavitation
    Publication number: 20170051231
    Abstract: A method of extracting CBD, THC, desirable oils, and other compounds from the cannabis plant includes drying the plant, grinding or chopping the plant, mixing the resulting pieces of the plant with a fluid to form a mixture, circulating the mixture through a controlled cavitation reactor to liberate CBD, THC, desirable oils, and other compounds from the pieces, and separating the liberated CBD, THC, desirable oils, and other compounds from the fluid. The method may be used as an adjunct to or in combination with traditional extraction techniques such as leaching to increase yields.
    Type: Application
    Filed: August 18, 2016
    Publication date: February 23, 2017
    Inventor: Douglas G. Mancosky
  • Methods for converting CBD to tetrahydrocannabinols
    Patent number: 11767306
    Abstract: This disclosure provides a method for converting CBD to a tetrahydrocannabinol featuring the use of cheap and non-toxic aluminum isopropoxide as a catalyst. The method comprises (a) providing a reaction mixture comprising a catalyst in an organic solvent, wherein the catalyst comprises aluminum isopropoxide; (b) adding a reagent comprising CBD to the reaction mixture; (c) mixing the reaction mixture and allowing a reaction for converting CBD to a tetrahydrocannabinol to occur for a predetermine period of time; (d) removing the catalyst by filtration upon the completion of the reaction; (e) removing the organic solvent; and (f) eluting the tetrahydrocannabinol from the organic phase.
    Type: Grant
    Filed: October 21, 2020
    Date of Patent: September 26, 2023
    Assignee: Cannacraft, Inc
    Inventor: Ahmad Dehestani
  • NOVEL METHODS AND RELATED TOOLS FOR CBD CONVERSION TO THC
    Publication number: 20200223814
    Abstract: The present invention is directed to methods of producing THC from CBD utilizing non-harsh methodology and resulting in substantially increased yields, as well as devices built upon these novel methods. The methods and devices are material efficient, and in certain embodiments, solvent-free. In particular, in certain embodiments, these methods and related devices are suitable for commercial production of THC from CBD. Furthermore, in certain embodiments, the present invention provides methods of producing THC from CBD in manner that affords tunability to select the ratio of THC-8 to THC-9.
    Type: Application
    Filed: January 13, 2020
    Publication date: July 16, 2020
    Inventor: Alex Nivorozhkin
  • METHODS AND RELATED TOOLS FOR CBD CONVERSION TO THC
    Publication number: 20210363125
    Abstract: The present invention is directed to methods of producing THC from CBD utilizing non-harsh methodology and resulting in substantially increased yields, as well as devices built upon these novel methods. The methods and devices are material efficient, and in certain embodiments, solvent-free. In particular, in certain embodiments, these methods and related devices are suitable for commercial production of THC from CBD. Furthermore, in certain embodiments, the present invention provides methods of producing THC from CBD in manner that affords tunability to select the ratio of THC-8 to THC-9.
    Type: Application
    Filed: August 9, 2021
    Publication date: November 25, 2021
    Inventor: Alex Nivorozhkin
  • FILMS FOR FLEXIBLE APPLICATIONS USING CELLULOSE NANOCRYSTALS (CNC) AND RESILIN-CBD
    Publication number: 20230203258
    Abstract: An electronic device element is described which is flexible, bendable or twistable without substantial degradation in optical or electrical properties. The electronic device element includes an optically transparent film constructed of a recombinant re-silin-CBD protein bound to cellulose nanocrystals (CNC). The recombinant resilin-CBD protein includes a Clostridium-derived cellulose-binding domain fused to resilin. The electronic device element may be a flexible display or flexible electronics element.
    Type: Application
    Filed: May 19, 2021
    Publication date: June 29, 2023
    Applicants: Smart Resilin Ltd., YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LT
    Inventors: Oded Shoseyov, Liron Nesiel, Amir Rudich, Daniel Voignac
  • Introducing a Metal Layer Between Sin and Tin to Improve CBD Contact Resistance for P-TSV
    Publication number: 20090160061
    Abstract: The present disclosure provide an integrated circuit. The integrated circuit includes a through-silicon-via (TSV) trench configured in a semiconductor substrate; a conductive pad formed on the semiconductor substrate, the conductive pad being adjacent the TSV trench; a silicon nitride layer disposed over the conductive pad and in the TSV trench; a titanium layer disposed on the silicon nitride layer; a titanium nitride layer disposed on the titanium layer; and a copper layer disposed on the titanium nitride layer.
    Type: Application
    Filed: September 8, 2008
    Publication date: June 25, 2009
    Applicant: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD.
    Inventors: Kuo-Ching Hsu, Chen-Shien Chen, Boe Su, Hon-Lin Huang
  • SYNERGISTIC COMBINATIONS OF ATORVASTATIN AND CANNABIDIOL (CBD)
    Publication number: 20230414532
    Abstract: The invention relates to pharmaceutical compositions comprising a statin and a cannabinoid, and their use for the treatment of hypercholesterolemia and atherosclerosis. It has been found that compositions combining a statin and a cannabinoid are improved over existing statin formulations. The compositions of the invention for example allow for a lower effective dose of statin and a reduction of the adverse effects seen with statins taken alone. Dosing ranges and formulations suitable for oral, buccal, and sublingual administration are disclosed. Various specific cannabinoids such as cannabidiol and synthetic cannabidiols selected for their anti-inflammatory, antioxidant, and anti-atherosclerotic effect are shown to be particularly advantageous.
    Type: Application
    Filed: September 3, 2023
    Publication date: December 28, 2023
    Inventors: Mathew Sherwood, James Smeeding
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