Search Patents
  • USE OF THE PHYTOCANNABINOID CANNABIDIOL (CBD) IN COMBINATION WITH A STANDARD ANTI-EPILEPTIC DRUG (SAED) IN THE TREATMENT OF EPILEPSY
    Publication number: 20140155456
    Abstract: The invention relates to the use of cannabidiol (CBD), at a dose of greater than 300 mg/day, in combination with a standard anti-epileptic drug (SAED) which acts via sodium or calcium channels, for use in the treatment of epilepsy. The SAED is preferably one which•modifies low-threshold or transient neuronal calcium currents,or•reduces high-frequency neuronal firing and sodium-dependent action potentials and enhances GABA effects. Preferred SAEDs are ethosuximide and valproate.
    Type: Application
    Filed: January 3, 2012
    Publication date: June 5, 2014
    Applicants: Otsuka Pharmaceutical Co., Limited, GW Pharma Limited
    Inventors: Ben Whalley, Claire Williams, Gary Stephens
  • USE OF THE PHYTOCANNABINOID CANNABIDIOL (CBD) IN COMBINATION WITH A STANDARD ANTI-EPILEPTIC DRUG (SAED) IN THE TREATMENT OF EPILEPSY
    Publication number: 20130296398
    Abstract: The invention relates to the use of cannabidiol (CBD), at a dose of greater than 300 mg/day, in combination with a standard anti-epileptic drug (SAED) which acts via sodium or calcium channels, for use in the treatment of epilepsy. The SAED is preferably one which•modifies low-threshold or transient neuronal calcium currents,or•reduces high-frequency neuronal firing and sodium-dependent action potentials and enhances GABA effects. Preferred SAEDs are ethosuximide and valproate.
    Type: Application
    Filed: January 3, 2012
    Publication date: November 7, 2013
    Applicants: Otsuka Pharmaceutical Co., Limited, GW Pharma Limited
    Inventors: Ben Whalley, Claire Williams, Gary Stephens
  • Method of extracting CBD, THC, and other compounds from cannabis using controlled cavitation
    Patent number: 10011804
    Abstract: A method of extracting CBD, THC, desirable oils, and other compounds from the cannabis plant includes drying the plant, grinding or chopping the plant, mixing the resulting pieces of the plant with a fluid to form a mixture, circulating the mixture through a controlled cavitation reactor to liberate CBD, THC, desirable oils, and other compounds from the pieces, and separating the liberated CBD, THC, desirable oils, and other compounds from the fluid. The method may be used as an adjunct to or in combination with traditional extraction techniques such as leaching to increase yields.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: July 3, 2018
    Assignee: EcoXtraction, LLC
    Inventor: Douglas G. Mancosky
  • Indigenous and Improved Bacterially Fermented CBD, CBG and Related Cannabinoid Oral Dosage Forms
    Publication number: 20200367548
    Abstract: The present invention is a cannabidiol (CBD), cannabigerol (CBG) or related cannabinoid oral dosage form including bacterially fermented hemp, typically compounded as a tablet or formulated within a capsule or as an additive to other dietary supplements or functional foods. The dosage forms contain dietary fiber, important to activity as the desired delivery system, having a ratio of one part soluble dietary fiber to 30 parts insoluble dietary fiber, which is an optimal fiber ratio for oral delivery and bioavailability of cannabidiol, cannabigerol and other desirable cannabinoids from either activated or native hemp.
    Type: Application
    Filed: April 3, 2020
    Publication date: November 26, 2020
    Applicant: BYO Holdings, LLC
    Inventor: Jordan Seth Rubin
  • Cannabidiol (CBD) Enriched Alcohol
    Publication number: 20160158299
    Abstract: A cannabinoid enriched alcohol composition for human consumption and method of manufacture for the composition are disclosed. The composition includes by weight about ninety-nine point nine-two percent (99.92%) ethanol in a liquid state and by weight about zero point zero eight percent (0.08%) cannabinoid in a liquid state. The composition is made by providing the ethanol in a liquid state and by providing the cannabinoid in the form of a cannabidiol oil in a liquid state, further a next step of combining the ethanol and the cannabidiol oil forming an initial mixture and agitating the initial mixture until the cannabidiol oil and the ethanol are in a substantially emulsified state with one another in a liquid state forming a completed mixture.
    Type: Application
    Filed: December 4, 2015
    Publication date: June 9, 2016
    Inventor: Bradley Michael Bohus
  • Electrically stimulated CBD infused anesthetic patch system
    Patent number: 10682508
    Abstract: An electrically stimulated CBD infused anesthetic patch system that is placed on a human's skin that is used to relieve pain. The electrically stimulated CBD infused anesthetic patch system comprises of a transdermal patch that has electrodes that receive an electric current from a TENS device. The transdermal patch is impregnated with a solution that has at least one analgesic that is selected from the group consisting of Menthol, CBD, Lidocaine or Capsaicin. The solution shall also include inactive ingredients.
    Type: Grant
    Filed: April 4, 2019
    Date of Patent: June 16, 2020
    Inventors: Trevor Theriot, Quanqin Dai, Mark Julian, Joseph Horton, John Lasso
  • Methods and related tools for CBD conversion to THC
    Patent number: 11098024
    Abstract: The present invention is directed to methods of producing THC from CBD utilizing non-harsh methodology and resulting in substantially increased yields, as well as devices built upon these novel methods. The methods and devices are material efficient, and in certain embodiments, solvent-free. In particular, in certain embodiments, these methods and related devices are suitable for commercial production of THC from CBD. Furthermore, in certain embodiments, the present invention provides methods of producing THC from CBD in manner that affords tunability to select the ratio of THC-8 to THC-9.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: August 24, 2021
    Assignee: ARIELIUM HEALTH, LLC
    Inventor: Alex Nivorozhkin
  • Methods and Systems to Measure Cannabidiol (CBD)
    Publication number: 20200326355
    Abstract: Disclosed are methods, systems and computer-program products to measure cannabidiol (CBD) and/or its metabolites in a biological sample. The methods and systems may include LC-MS/MS. For example the method may include obtaining MS/MS data comprising a predetermined MS/MS transition for THC and/or at least one THC metabolite and CBD and/or at least one CBD metabolite, and determining a ratio of the amount of the CBD and/or at least one CBD metabolite to the amount of the THC and/or at least one THC metabolite for the biological sample. In certain embodiments, the methods and/or systems are used to distinguish CBD from THC use in a subject.
    Type: Application
    Filed: April 15, 2020
    Publication date: October 15, 2020
    Inventors: Gregory C. Janis, Melissa M. Goggin
  • Cannabidiol (CBD) enriched alcohol
    Patent number: 9539295
    Abstract: A cannabinoid enriched alcohol composition for human consumption and method of manufacture for the composition are disclosed. The composition includes by weight about ninety-nine point nine-two percent (99.92%) ethanol in a liquid state and by weight about zero point zero eight percent (0.08%) cannabinoid in a liquid state. The composition is made by providing the ethanol in a liquid state and by providing the cannabinoid in the form of a cannabidiol oil in a liquid state, further a next step of combining the ethanol and the cannabidiol oil forming an initial mixture and agitating the initial mixture until the cannabidiol oil and the ethanol are in a substantially emulsified state with one another in a liquid state forming a completed mixture.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: January 10, 2017
    Inventor: Bradley Michael Bohus
  • Pharmaceutical Composition Comprising Cannabidiol (CBD) and Lecithin
    Publication number: 20190151398
    Abstract: The present invention relates to a pharmaceutical composition comprising non-decarboxylated ?9 Tetrahydrocannabinol (THC), Cannabidiol (CBD), and at least one small molecule selected from Citric Acid, Ascorbic Acid, Citrus Essential Oil(s), Lecithin, one or more sugar(s), Resveratrol, and combinations thereof, wherein the composition exhibits enhanced therapeutic potency of THC and/or CBD. The present invention is further directed to methods of treating one or more disease(s) or disorder(s) modulated by the activation of the Cannabinoid CB1 and/or CB2 receptors, by administering a therapeutically effective amount of the composition of the present invention to a subject in need thereof.
    Type: Application
    Filed: March 22, 2017
    Publication date: May 23, 2019
    Inventor: Brooks John Kelly
  • BIOIDENTICAL PROGESTERONE CREAM INFUSED WITH NANOEMULSIFIED CBD
    Publication number: 20220105107
    Abstract: The present invention is a transdermal composition, for self-administering bioidentical hormone replacement and hormone balancing therapy and hormone balancing for both women and men, using a combination of progesterone and Cannabidiol (CBD) in various forms including nano-emulsified configurations. The compositions, which are topically applied by the user are trans dermally or topically delivered to the vascular system of the user in accordance with a dosage protocol established that will optimize the hormone levels of the user. Specific properties of CBD when combined with progesterone can provide an “entourage effect” that is produced from the synergistic interaction of the cannabinoids and progesterone in the user. The composition may also comprise various other excipients.
    Type: Application
    Filed: October 1, 2020
    Publication date: April 7, 2022
    Inventor: Michael Liguori
  • Oxygenated alkyl substituted bicyclo alkanes
    Patent number: 4689345
    Abstract: Anti-androgenic composition compound of the formula ##STR1## wherein Q is CO, CH(OR), CR(OH), or CR (OC)-lower alkyl);R is H, or C.sup.1-2 -alkyl;X is hydroxyalkyl, methoxy-C.sup.2-11 -alkyl, ethoxy-C.sup.2-11 -alkyl or oxo-C.sup.2-11 -alkyl, formyl-C.sup.2-11 -alkyl, carboxy-C.sup.2-11 -alkyl or (C.sub.1-2 -alkyl) oxycarbonyl-C.sup.2-11 -alkyl;c is 1 or 2;p or w are 0, 1 or 2 and the sum of p and w is 1 to 4;and a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 12, 1986
    Date of Patent: August 25, 1987
    Assignee: CBD Corporation
    Inventors: Walter J. Kasha, Chantal S. Burnison
  • THERAPEUTIC OR EXERCISE ELASTOMER PUTTY SPECIALLY FORMULATED WITH CBD OIL AND/OR DMSO TO REDUCE PAIN AND INFLAMMATION DURING HAND EXERCISE OR REHABILITATION
    Publication number: 20230405385
    Abstract: A therapeutic or exercise putty includes a boronated silicone elastomer serving as the base ingredient or component and CBD or CBG oil or powder, DMSO, or CBD or CBG oil or powder together with DMSO, as a secondary ingredient mixed with the base putty. The inclusion of any one of the aforementioned secondary ingredients will reduce the pain and inflammation when the putty is used for hand rehabilitation or exercise by users and patients. Added side effects of reduced stress, tension or discomfort also contribute to a positive rehabilitation exercise experience that supports better user or patient health.
    Type: Application
    Filed: May 23, 2023
    Publication date: December 21, 2023
    Inventors: M. Gregory Minuto, Stephen Mlcoch
  • INDIGENOUS AND IMPROVED BACTERIALLY FERMENTED CBD, CBG AND RELATED CANNABINOID ORAL DOSAGE FORMS
    Publication number: 20230285304
    Abstract: The present invention is a cannabidiol oral dosage form including predominantly or exclusively bacterially fermented hemp pomace, compounded as a tablet or formulated within a capsule generally without the addition of synthetic excipients, fillers or other additives, not including the inevitable presence of some moisture. The dosage forms contain dietary fiber, important to activity as the desired delivery system, having a ratio of one part soluble dietary fiber to 30 parts insoluble dietary fiber and delivers desirable/non hallucinogenic cannabinoids (CBD, CBG, etc.) in a ratio of 60:1 up to 120:1 to hallucinogenic cannabinoids (THC).
    Type: Application
    Filed: November 2, 2022
    Publication date: September 14, 2023
    Applicant: Fermented Farmer, LLC
    Inventor: Jordan Seth Rubin
  • Cannabidiol (CBD) as Chemical for Treating Aging-related Degenerative Diseases and Promoting Health Aging
    Publication number: 20220354805
    Abstract: The invention relates to the technical field of medicine, and provides a method of screening and identifying small molecule with anti-aging properties. The method comprises cellular models, namely premature aging mouse embryonic fibroblasts and human HGPS mesenchymal stem cells and animal models, namely premature aging progeroid mice and Caenorhabditis elegans. The method successfully screened and identified Cannabidiol (CBD), which had senolytic effects. The invention also determined that the optimal concentration of CBD treatment is 10-20 ?M.
    Type: Application
    Filed: April 29, 2022
    Publication date: November 10, 2022
    Inventors: Sheung Kin Ken Wong, Zhongjun Zhou, Xuelai Wang, Jing Chen, Leung Kris Ying, Jian Zhang
  • Oxygenated alkyl substituted bicyclo alkanes
    Patent number: 4855322
    Abstract: A compound of the formula ##STR1## wherein Q is CO, CH(OR), CR(OH), or CR (OC)-lower alkyl); R is H, or C.sup.1-2 -alkyl;X is hydroxyalkyl,methoxy-C.sup.2-11 -alkyl, ethoxy-C.sup.2-11 -alkyl or oxo-C.sup.2-11 -alkyl, formyl-C.sup.2-11 -alkyl,carboxy-C.sup.2-11 -alkyl or (C.sub.1-2 -alkyl) oxycarbonyl-C.sup.2-11 -alkyl;c is 1 or 2;p or w are 0, 1 or 2 and the sum of p and w is 1 to 4;and a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 1, 1987
    Date of Patent: August 8, 1989
    Assignee: CBD Corporation
    Inventors: Walter J. Kasha, Chantal S. Burnison
  • CBD (CHEMICAL BATH DEPOSITION) FILM FORMATION APPARATUS AND METHOD FOR PRODUCING BUFFER LAYER
    Publication number: 20130224895
    Abstract: A support-heat unit that supports and heats a substrate from the back side of the substrate, a reaction bath having an opening for supplying a CBD reaction solution for forming a film onto a front surface of the substrate, which is supported by the support-heat unit, and a reaction bath forward-backward drive unit that can press the opening onto the front surface of the substrate by moving the reaction bath toward the front surface of the substrate, which is supported by the support-heat unit, and that can detach the opening from the front surface of the substrate by moving the reaction bath away from the front surface of the substrate are provided.
    Type: Application
    Filed: April 12, 2013
    Publication date: August 29, 2013
    Applicant: FUJIFILM Corporation
    Inventor: FUJIFILM Corporation
  • An Electrically Stimulated CBD Infused Pain-Relieving Patch
    Publication number: 20200316364
    Abstract: An electrically stimulated CBD infused pain-relieving patch that is placed on a human's skin that is used to relieve pain when it is connected to a controlled electrical current generating device. The electrically stimulated CBD infused pain-relieving patch comprises of a carrier that has at least one electrode, at least one conductive electrode sheet that is attached to the carrier, and a conductive gel that is placed on the electrode sheet. The conductive gel contains at least one analgesic that is selected from the group consisting of Menthol, CBD, Lidocaine or Capsaicin. The conductive gel has inactive ingredients.
    Type: Application
    Filed: April 7, 2019
    Publication date: October 8, 2020
    Inventors: Quanqin Dai, John Lasso, Joseph Horton, Mark Julian, Trevor Theriot
  • INDIGENOUS AND IMPROVED BACTERIALLY FERMENTED CBD, CBG AND RELATED CANNABINOID ORAL DOSAGE FORMS
    Publication number: 20210106533
    Abstract: The present invention is a cannabidiol oral dosage form including predominantly or exclusively bacterially fermented hemp pomace, compounded as a tablet or formulated within a capsule generally without the addition of synthetic excipients, fillers or other additives, not including the inevitable presence of some moisture. The dosage forms contain dietary fiber, important to activity as the desired delivery system, having a ratio of one part soluble dietary fiber to 30 parts insoluble dietary fiber and delivers desirable/non hallucinogenic cannabinoids (CBD, CBG, etc.) in a ratio of 60:1 up to 120:1 to hallucinogenic cannabinoids (THC).
    Type: Application
    Filed: April 29, 2020
    Publication date: April 15, 2021
    Applicant: Beyond Hemp, LLC
    Inventor: Jordan Seth Rubin
  • Method of Manufacture for Liquid Cannabinoids, and Modified CBD Oil Composition
    Publication number: 20230059698
    Abstract: A method of manufacturing a cannabinoid solution. The method first comprises providing a solution containing a volume of cannabidiol (CBD), as an oil. Preferably, the solution comprises at least 80% by volume of the CBD oil. The method also includes placing the volume of CBD oil into a container. The method further comprises determining a vibrational frequency of energy. The method then includes applying the determined vibrational frequency of energy to the solution within the container in order to imprint the volume of cannabinoid solution with the determined vibrational frequency. A cannabinoid solution comprising a volume of cannabidiol (CBD), as an oil, is also provided. The solution has been imprinted with one or more selected vibrational frequencies of energy.
    Type: Application
    Filed: June 21, 2022
    Publication date: February 23, 2023
    Inventor: Thomas L. Lucky
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