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Publication number: 20120270794Abstract: The invention provides human polymorphisms that are associated with Parkinson's disease (PD). Also disclosed are compositions and methods for use in diagnostics, prognostics, prevention, treatment and/or study of PD.Type: ApplicationFiled: April 20, 2012Publication date: October 25, 2012Applicant: 23andMe, Inc.Inventors: Nicholas Eriksson, Chuong Do
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Patent number: 8187811Abstract: The invention provides human polymorphisms that are associated with Parkinson's disease (PD). Also disclosed are compositions and methods for use in diagnostics, prognostics, prevention, treatment and/or study of PD.Type: GrantFiled: November 30, 2010Date of Patent: May 29, 2012Assignee: 23andMe, Inc.Inventors: Nicholas Eriksson, Chuong Do
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Patent number: 10891317Abstract: Assembling a cohort includes: receiving genetic characteristic information pertaining to a desired genetic characteristic; using the genetic characteristic information to search a data storage comprising information of previously genotyped individuals to derive a candidate group having the desired genetic characteristic; and assembling the cohort based at least in part on the candidate group.Type: GrantFiled: October 12, 2018Date of Patent: January 12, 2021Assignee: 23andMe, Inc.Inventors: Arnab Chowdry, Alexander Kompel, Michael Polcari
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Patent number: 9836576Abstract: Phasing unphased genotype data of an individual includes: obtaining the unphased genotype data of the individual; processing the unphased genotype data to determine phased haplotype data, the processing comprising performing out-of-sample population-based phasing on the unphased genotype data; wherein: performing out-of-sample population-based phasing includes performing statistical analysis using predetermined reference data that is based on genotype data of a reference population; and the genotype data of the reference population does not reference the genotype data of the individual.Type: GrantFiled: March 13, 2013Date of Patent: December 5, 2017Assignee: 23andMe, Inc.Inventors: Chuong Do, Eric Durand, John Michael Macpherson
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Patent number: 10643740Abstract: Displaying a comparison of genetic data is disclosed, including receiving an indication of a first individual, receiving an indication of a second individual, retrieving the genotypic information for the first individual and the second individual, comparing the genotypic information of the first individual and the second individual, displaying an indication of the comparison of the genotypic information of the first individual and the second individual graphically. A first graphical symbol is used to display an indication of the genome regions for which the first individual and the second individual are identical. A second graphical symbol is used to display an indication of the genome regions for which the first individual and the second individual are half identical.Type: GrantFiled: May 10, 2019Date of Patent: May 5, 2020Assignee: 23andMe, Inc.Inventors: Linda Avey, Oleksiy Khomenko, Brian Thomas Naughton, Serge Saxonov, Anne Wojcicki, Alexander Wong
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Patent number: 11935628Abstract: Determining relative relationships of people who share a common ancestor within at least a threshold number of generations includes: receiving recombinable deoxyribonucleic acid (DNA) sequence information of a first user and recombinable DNA sequence information of a plurality of users; processing, using one or more computer processors, the recombinable DNA sequence information of the plurality of users in parallel; determining, based at least in part on a result of processing the recombinable DNA information of the plurality of users in parallel, a predicted degree of relationship between the first user and a user among the plurality of users, the predicted degree of relative relationship corresponding to a number of generations within which the first user and the second user share a common ancestor.Type: GrantFiled: November 2, 2022Date of Patent: March 19, 2024Assignee: 23andMe, Inc.Inventors: Lawrence Hon, Serge Saxonov, Brian Thomas Naughton, Joanna Louise Mountain, Anne Wojcicki, Linda Avey