Abstract: A system and method to integrate computational fluid dynamics (CFD) and radiotherapy data for accurate simulation of spatio-temporal flow and deformation in real human lung is presented. The method utilizes a mathematical formulation that fuses the CFD predictions of lung displacement with the corresponding radiotherapy data using the theory of Tikhonov regularization.
Type:
Application
Filed:
July 13, 2016
Publication date:
January 19, 2017
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
Abstract: A system and method to integrate computational fluid dynamics (CFD) and radiotherapy data for accurate simulation of spatio-temporal flow and deformation in real human lung is presented. The method utilizes a mathematical formulation that fuses the CFD predictions of lung displacement with the corresponding radiotherapy data using the theory of Tikhonov regularization.
Type:
Grant
Filed:
July 13, 2016
Date of Patent:
May 14, 2019
Assignees:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
Abstract: A wind flow sensing system determines a first approximation of the velocity field at each of the altitudes by simulating computational fluid dynamics (CFD) of the wind flow with operating parameters reducing a cost function of a weighted combination of errors, determines a horizontal derivative of vertical velocity at each of the altitudes from the first approximation of the velocity fields, and determines a second approximation of the velocity fields using geometric relationships between a velocity field for each of the altitudes, projections of the measurements of radial velocities on the three-dimensional axes, and the horizontal derivative of vertical velocity for the corresponding velocity field. In the cost function of the CFD, each error corresponds to one of the altitudes and includes a difference between measured velocities at the line-of-site points at the corresponding altitude and simulated velocities at the line-of-site points simulated by the CFD for the corresponding altitude.
Type:
Grant
Filed:
March 20, 2018
Date of Patent:
October 6, 2020
Assignee:
Mitsubishi Electric Research Laboratories, Inc.
Abstract: Systems and methods provide a novel computational approach to planning the endovascular treatment of cardiovascular diseases. In particular, the invention simulates medical device deployment and hemodynamic outcomes using a virtual patient-specific anatomical model of the area to be treated, high-fidelity finite element medical device models and computational fluid dynamics (CFD). In an embodiment, the described approach investigates the effects of coil packing density, coil shape, aneurysmal neck size and parent vessel flow rate on aneurysmal hemodynamics. A processor may receive patient clinical data used to construct the relevant anatomical structure model. The processor may access medical device models constructed using finite element analysis and three dimensional beam analysis, and simulates the deployment of selected medical devices in the anatomical structure model.
Type:
Grant
Filed:
January 26, 2015
Date of Patent:
May 14, 2019
Assignees:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, MAYO FOUNDATION FOR MEDICAL EDUCATION & RESEARCH
Inventors:
Mohamed Haithem Babiker, David H. Frakes, Brian W. Chong
Abstract: A method for designing a combustion system which emits less of at least one environmentally-harmful emission is presented. In a describing step, an injector which introduces a fuel into a combustion chamber is described via a CFD code. In a modeling step, combustion kinetics of the fuel are modeled via a pre-processing code as the fuel mixes and reacts with an oxidizer. In a first selecting step, at least one primary scalar is derived during the modeling of the combustion kinetics. In a performing step, a table look-up is performed to obtain at least one data from a look-up database based on the primary scalar. In a second selecting step, at least one secondary scalar is selected in addition to the primary scalar(s). In a specifying step, at least one chemical pathway of formation or destruction for the secondary scalar is specified via a chemistry manager wherein the secondary scalar is representative of the environmentally-harmful emission(s) of the chemical pathway(s).
Type:
Grant
Filed:
July 1, 2022
Date of Patent:
October 24, 2023
Assignee:
Combustion Research and Flow Technology, Inc.
Inventors:
Andrea C. Zambon, Balaji Muralidharan, William H. Calhoon, Jr., Ashvin Hosangadi
Abstract: Computer simulation was used in the development of an inward-burning, radial matrix gas burner and heat pipe heat exchanger. The burner and exchanger can be used to heat a Stirling engine on cloudy days when a solar dish, the normal source of heat, cannot be used. Geometrical requirements of the application forced the use of the inward burning approach, which presents difficulty in achieving a good flow distribution and air/fuel mixing. The present invention solved the problem by providing a plenum with just the right properties, which include good flow distribution and good air/fuel mixing with minimum residence time. CFD simulations were also used to help design the primary heat exchanger needed for this application which includes a plurality of pins emanating from the heat pipe. The system uses multiple inlet ports, an extended distance from the fuel inlet to the burner matrix, flow divider vanes, and a ring-shaped, porous grid to obtain a high-temperature uniform-heat radial burner.
Abstract: Potable drinking water is a scarce resource in many parts of developing countries, especially rural areas. Due to limited financial means of these countries, low cost point-of-use systems are thought to be appropriate technology to treat water. Systems using solar ultraviolet (UV) radiation could be successful since many vulnerable countries are located where solar radiation is intense and abundant throughout the year. The goal of this disclosure is to develop a simple and low cost point-of-use solar UV reactor to disinfect water. In this disclosure wavelength-dependent microbial dose-response behavior was investigated using surrogates to pathogenic microbes. A solar radiation prediction method based on the SMARTS model was used to predict solar UV intensity as function of geographic location and time. A numerical modeling procedure using the discrete ordinate (DO) model and CFD software (FLUENT) was used to simulate UV dose (distribution) delivery to microorganisms.
Type:
Application
Filed:
August 29, 2012
Publication date:
August 14, 2014
Applicant:
PURDUE RESEARCH FOUNDATION
Inventors:
Ernest R Blatchley, III, Eric Gentil Mbonimpa, Bruce Applegate, Bryan Vadheim
Abstract: Potable drinking water is a scarce resource in many parts of developing countries, especially rural areas. Due to limited financial means of these countries, low cost point-of-use systems are thought to be appropriate technology to treat water. Systems using solar ultraviolet (UV) radiation could be successful since many vulnerable countries are located where solar radiation is intense and abundant throughout the year. The goal of this disclosure is to develop a simple and low cost point-of-use solar UV reactor to disinfect water. In this disclosure wavelength-dependent microbial dose-response behavior was investigated using surrogates to pathogenic microbes. A solar radiation prediction method based on the SMARTS model was used to predict solar UV intensity as function of geographic location and time. A numerical modeling procedure using the discrete ordinate (DO) model and CFD software (FLUENT) was used to simulate UV dose (distribution) delivery to microorganisms.
Type:
Grant
Filed:
August 29, 2012
Date of Patent:
January 17, 2017
Assignee:
Purdue Research Foundation
Inventors:
Ernest R Blatchley, III, Eric Gentil Mbonimpa, Bruce Applegate, Bryan Vadheim
Abstract: A multidisciplinary structural design optimization method for a fuel assembly based on co-simulation takes the fuel assembly as a research object, and establishes a surrogate model by determining appropriate optimization design parameters with respect to the optimization requirements and low design of experiments efficiency of the fuel assembly under the working conditions of flow, solid and thermal multidisciplinary coupling. At the same time, the method combines optimization algorithms to realize the structural optimization design of a flaky fuel assembly with multiple narrow flow channels based on the characteristic of rapid optimization of ISIGHT, thereby effectively solving the problem of uneven temperature distribution of the structure.