Search Patents
  • BRAIN INJURY BIOMARKER PANEL
    Publication number: 20120322682
    Abstract: A panel of biomarkers for diagnosis, monitoring of progression and prognosis of various brain injuries and PTSD.
    Type: Application
    Filed: June 19, 2012
    Publication date: December 20, 2012
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: John MCDEVITT, Nicolaos CHRISTODOULIDES, Pierre N. FLORIANO
  • COMPOSITION AND USES THEREOF
    Publication number: 20150174232
    Abstract: An immunogenic composition comprising the Nm-ACP protein or an immunogenic part thereof or an analogue thereof, wherein the composition is capable of eliciting an immune response when administered to a human or non-human animal.
    Type: Application
    Filed: June 20, 2013
    Publication date: June 25, 2015
    Inventors: Myron Christodoulides, John Edwards Heckels
  • DETECTING TUMOR BIOMARKER IN ORAL CANCER
    Publication number: 20080038738
    Abstract: Methods and device for detecting the presence of tumor biomarkers in oral squamous cell carcinoma.
    Type: Application
    Filed: May 10, 2007
    Publication date: February 14, 2008
    Inventors: Shannon Weigum, Pierre Floriano, Nicolaos Christodoulides, John McDevitt
  • BIO-NANO-CHIP FOR ANTICONVULSANT DRUG SALIVARY ASSAY
    Publication number: 20150111778
    Abstract: This disclosure describes portable bio-nano-chip (BNC) assays of antiepileptic drugs (AED) using salivary samples. The BNC technology results in a more convenient, less expensive, and less time consuming sampling and analysis.
    Type: Application
    Filed: October 1, 2014
    Publication date: April 23, 2015
    Inventors: John T. MCDEVITT, Nicolaos CHRISTODOULIDES, Giridhar P. KALAMANGALAM
  • DETECTING HUMAN OR ANIMAL IMMUNOGLOBIN-E
    Publication number: 20080176253
    Abstract: Methods, systems, and apparatus for detecting the presence of human or animal immunoglobin-E are described. A fluid or gas sample may pass through a particle-based detection system of a cartridge. Detection and analysis techniques may be applied to determine the identity and quantity of the captured IgE.
    Type: Application
    Filed: May 10, 2007
    Publication date: July 24, 2008
    Inventors: Nicolaos Christodoulides, Pierre N. Floriano, Karri Ballard, John T. McDevitt
  • DETECTING MULTIPLE TYPES OF LEUKOCYTES
    Publication number: 20080050830
    Abstract: Methods, systems, and apparatus for detecting multiple types of leukocytes in a blood sample material. A fluid or gas sample may pass through a sieve-based detection system of a cartridge. Detection and analysis techniques may be applied to determine the relative distribution of multiple types of white blood cells in the sample.
    Type: Application
    Filed: May 10, 2007
    Publication date: February 28, 2008
    Inventors: Pierre Floriano, Nicolaos Christodoulides, Karri Ballard, John McDevitt
  • Oral cancer point of care diagnostics
    Patent number: 9535068
    Abstract: A point of care diagnostic test, device and disposables for determining a patient risk for oral cancer in the same visit that a sample is collected.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: January 3, 2017
    Assignee: William Marsh Rice University
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Martin Thornhill, Spencer Redding, Nadarajah Vigneswaran, Craig Murdoch, Paul Speight
  • CARDIBIOINDEX/CARDIBIOSCORE AND UTILITY OF SALIVARY PROTEOME IN CARDIOVASCULAR DIAGNOSTICS
    Publication number: 20080300798
    Abstract: Embodiments of the invention include methods by which cardiac biomarkers are assigned an index (cardiovascular biomarker index-cardiobioindex, CBI) as a means to describe the utility of each biomarker, or combination of biomarkers for risk evaluation, diagnosis or prognosis of cardiovascular disease status.
    Type: Application
    Filed: April 16, 2008
    Publication date: December 4, 2008
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Craig S. Miller, Jeffrey L. Ebersole
  • Capture and detection of microbes by membrane methods
    Publication number: 20060079000
    Abstract: Methods and systems for detecting the presence of analytes using a membrane based detection system are described. A fluid sample is passed through a membrane based detection system (100). Particulate analytes (e.g., microbes) are captured by the membrane (110). Detection and analysis techniques may be applied to determine the identity and quantity of the captured analytes.
    Type: Application
    Filed: January 24, 2005
    Publication date: April 13, 2006
    Inventors: Pierre Floriano, John McDevitt, Nick Christodoulides
  • Capture and detection of microbes by membrane methods
    Publication number: 20060073585
    Abstract: Methods and systems for detecting the presence of analytes using a membrane based detection system are described. A fluid sample is passed through a membrane based detection system (100). Particulate analytes (e.g., microbes) are captured by the membrane (110). Detection and analysis techniques may be applied to determine the identity and quantity of the captured analytes.
    Type: Application
    Filed: January 24, 2005
    Publication date: April 6, 2006
    Inventors: John McDevitt, Pierre Floriano, Nick Christodoulides
  • ORAL CANCER POINT OF CARE DIAGNOSTICS
    Publication number: 20130295580
    Abstract: A point of care diagnostic test, device and disposables for determining a patient risk for oral cancer in the same visit that a sample is collected.
    Type: Application
    Filed: November 11, 2011
    Publication date: November 7, 2013
    Applicants: William Marsh Rice University, University of Sheffield, The Board of Regents of the University of Texas System
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Martin Thornhill, Spencer Redding, Nadarajah Vigneswaran, Craig Murdoch, Paul Speight
  • System and Method for Disease Surveillance and Disease Severity Monitoring for COVID-19
    Publication number: 20210311055
    Abstract: This disclosure describes portable bio-nano-chip assays, methods and compositions for diagnosing and assessing pathogen-mediated diseases or infections at point-of-care using biological samples. The assays, methods and compositions provide in a more convenient, less expensive, and less time-consuming sampling and analysis.
    Type: Application
    Filed: March 25, 2021
    Publication date: October 7, 2021
    Inventors: John T. McDevitt, Michael P. McRae, Nick Christodoulides, Kritika Srinivasan
  • IMMUNOGENIC COMPOSITION COMPRISING NEISSERIA MENIGITIDIS MACROPHAGE INFECTIVITY POTENTIATOR PROTEIN
    Publication number: 20130230579
    Abstract: An immunogenic composition comprising the Nm-MIP protein or an immunogenic part thereof or an analogue thereof, wherein the composition is capable of eliciting an immune response when administered to a human or non-human animal, and uses thereof. A pharmaceutical composition or a vaccine composition comprising the Nm-MIP protein or an immunogenic part thereof or an analogue thereof.
    Type: Application
    Filed: September 9, 2011
    Publication date: September 5, 2013
    Applicant: UNIVERSITY OF SOUTHAMPTON
    Inventors: John Edward Heckels, Myron Christodoulides
  • IMMUNOGENIC COMPOSITION COMPRISING NEISSERIA MENINGITIDIS MACROPHAGE INFECTIVITY POTENTIATOR PROTEIN AND METHODS FOR USING THEM
    Publication number: 20160120971
    Abstract: An immunogenic composition comprising the Nm-MIP protein or an immunogenic part thereof or an analogue thereof, wherein the composition is capable of eliciting an immune response when administered to a human or non-human animal, and uses thereof. A pharmaceutical composition or a vaccine composition comprising the Nm-MIP protein or an immunogenic part thereof or an analogue thereof.
    Type: Application
    Filed: December 29, 2015
    Publication date: May 5, 2016
    Inventors: John Edward Heckels, Myron Christodoulides
  • METHOD AND SYSTEM FOR MANIPULATING FLUID MEDIUM
    Publication number: 20110023973
    Abstract: A system for manipulating a fluid medium is disclosed. The system comprises a plurality of particles suspended in the fluid medium, and a light source configured for irradiating the particles by light to induce nonlinear optical effects. The particles are constituted such that the nonlinear optical effects result in drag forces exerted by the particles on the fluid medium. The magnitude of the drag forces is sufficient to establish hydrodynamic flow of the fluid medium.
    Type: Application
    Filed: March 25, 2009
    Publication date: February 3, 2011
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Mordechai Segev, Demetrios N. Christodoulides, Carmel Rotschild
  • PROSTATE CANCER POINT OF CARE DIAGNOSTICS
    Publication number: 20130274136
    Abstract: The invention relates to point of care diagnostic disposables, devices, methods, and systems for diagnosing or predicting prostate cancer. The present invention employs biomarker specific reagents in disposable cassettes or lab cards for use as analyzers, as well as software to evaluate and report test results. The system promises to improve point of care in vitro diagnostics.
    Type: Application
    Filed: November 11, 2011
    Publication date: October 17, 2013
    Applicants: UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER, WILLIAM MARSH RICE UNIVERSITY
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Ian Thompson
  • Prostate cancer point of care diagnostics
    Patent number: 9671413
    Abstract: The invention relates to point of care diagnostic disposables, devices, methods, and systems for diagnosing or predicting prostate cancer. The present invention employs biomarker specific reagents in disposable cassettes or lab cards for use as analyzers, as well as software to evaluate and report test results. The system promises to improve point of care in vitro diagnostics.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: June 6, 2017
    Assignees: William Marsh Rice University, Board of Regents of the University of Texas System
    Inventors: John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Ian Thompson
  • Method and system for manipulating fluid medium
    Patent number: 8669119
    Abstract: A system for manipulating a fluid medium is disclosed. The system comprises a plurality of particles suspended in the fluid medium, and a light source configured for irradiating the particles by light to induce nonlinear optical effects. The particles are constituted such that the nonlinear optical effects result in drag forces exerted by the particles on the fluid medium. The magnitude of the drag forces is sufficient to establish hydrodynamic flow of the fluid medium.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: March 11, 2014
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Mordechai Segev, Demetrios N. Christodoulides, Carmel Rotschild
  • SYSTEMS AND METHODS INCLUDING SELF-CONTAINED CARTRIDGES WITH DETECTION SYSTEMS AND FLUID DELIVERY SYSTEMS
    Publication number: 20100291588
    Abstract: Methods, systems, and apparatus for detecting the presence of analytes are described. A fluid or gas sample may pass through a microsieve-based detection system and/or a particle-based detection system of a cartridge. Detection and analysis techniques may be applied to determine the identity and quantity of the captured analytes.
    Type: Application
    Filed: June 23, 2006
    Publication date: November 18, 2010
    Applicant: The Board of Regents of the University of Texas System
    Inventors: John T. McDevitt, Karri Ballard, Nicolaos J. Christodoulides, Pierre N. Floriano, Glennon W. Simmons
  • Channel allocation method and apparatus
    Publication number: 20060148483
    Abstract: A method for authenticating terminals in a wireless communication service involves receiving registration requests from terminals requiring access, transmitting to each of the terminals a signalling channel assignment signal allocating a duplex signalling channel uniquely to each terminal, transmitting in the signalling channel an authentication request signal, receiving an authentication response signal in the channel, the contents of which depend on the context of the authentication request signal, and deciding whether to allow access to the system according to the contents of the authentication response signal.
    Type: Application
    Filed: March 31, 2004
    Publication date: July 6, 2006
    Inventors: Chris Howard, Louis Christodoulides, Paul Febvre, David Mudge
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