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  • Methods, Kits and Compositions for Determining Severity and Survival of Heart Failure in a Subject
    Publication number: 20140100125
    Abstract: The application provides a method of determining a severity of heart failure in a human test subject, by determining a level of RNA encoded by one or more heart failure marker genes in blood of the test subject compared to controls. The application also provides a method of determining survival outcome and allows the ranking of test subjects based on the level of RNA encoded by one or more survival associated genes.
    Type: Application
    Filed: March 14, 2013
    Publication date: April 10, 2014
    Applicant: GENENEWS, INC.
    Inventor: GeneNews, Inc.
  • METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF
    Publication number: 20130324434
    Abstract: The present invention relates generally to the identification of biomarkers of conditions including disease and non-disease conditions as well as identifying compositions of biomarkers. The invention further provides a method of diagnosing disease, monitoring disease progression, and differentially diagnosing disease. The invention further provides for kits useful in diagnosing, monitoring disease progression and differentially diagnosing disease.
    Type: Application
    Filed: July 31, 2013
    Publication date: December 5, 2013
    Applicant: GeneNews Corporation
    Inventor: Choong-Chin Liew
  • Methods ofr the detection of gene trannscripts in blood and uses thereof
    Publication number: 20100124745
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: October 5, 2009
    Publication date: May 20, 2010
    Applicant: GeneNews Corporation
    Inventor: Choong-Chin Liew
  • METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF
    Publication number: 20100092984
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: October 5, 2009
    Publication date: April 15, 2010
    Applicant: GENENEWS CORPORATION
    Inventor: CHOONG-CHIN LIEW
  • METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF
    Publication number: 20110008780
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: April 9, 2010
    Publication date: January 13, 2011
    Applicant: GENENEWS CORPORATION
    Inventor: Choong-Chin Liew
  • Method of profiling gene expression in a subject having colorectal cancer
    Patent number: 8669058
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: March 11, 2014
    Assignee: GeneNews, Inc.
    Inventor: Choong-Chin Liew
  • Method for the detection of gene transcripts in blood and uses thereof
    Publication number: 20120165212
    Abstract: The present invention relates generally to the identification of biomarkers of conditions including disease and non disease conditions as well as identifying compositions of biomarkers. The invention further provides a method of diagnosing disease, monitoring disease progression, and differentially diagnosing disease. The invention further provides for kits useful in diagnosing, monitoring disease progression and differentially diagnosing disease.
    Type: Application
    Filed: January 27, 2012
    Publication date: June 28, 2012
    Applicant: GeneNews Corporation
    Inventor: Choong-Chin Liew
  • METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF
    Publication number: 20130102484
    Abstract: The present invention relates generally to the identification of biomarkers of conditions including disease and non disease conditions as well as identifying compositions of biomarkers. The invention further provides a method of diagnosing disease, monitoring disease progression, and differentially diagnosing disease. The invention further provides for kits useful in diagnosing, monitoring disease progression and differentially diagnosing disease.
    Type: Application
    Filed: October 4, 2012
    Publication date: April 25, 2013
    Applicant: GeneNews Corporation
    Inventor: CHOONG-CHIN LIEW
  • Method of profiling gene expression in a subject having diabetes
    Patent number: 8133674
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Grant
    Filed: April 9, 2010
    Date of Patent: March 13, 2012
    Assignee: GeneNews Corporation
    Inventor: Choong-Chin Liew
  • Method of profiling gene expression in a subject having disease
    Patent number: 8101358
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Grant
    Filed: April 9, 2010
    Date of Patent: January 24, 2012
    Assignee: GeneNews Corporation
    Inventor: Choong-Chin Liew
  • Diagnosis of mild osteoarthritis by determination of TNFAIP6 and TGFBI RNA levels
    Patent number: 7452667
    Abstract: The invention relates to the identification and selection of sequences which demonstrate particular advantage in identifying individuals having osteoarthritis (OA). The invention also provides a selection of sequences particularly useful in diagnosing the degree of advancement of osteoarthritis of an individual and in the identification of novel therapeutic targets for OA. The invention further provides for the use of these sequences as a tool to diagnose disease progression and to monitor the efficacy of therapeutic regimens.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: November 18, 2008
    Assignee: Genenews, Inc.
    Inventors: Choong-Chin Liew, K. Wayne Marshall, Hongwei Zhang
  • Method of profiling gene expression in a subject having disease
    Publication number: 20110008779
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: April 9, 2010
    Publication date: January 13, 2011
    Applicant: GeneNews Corporation
    Inventor: Choong-Chin Liew
  • METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF
    Publication number: 20100092983
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: October 5, 2009
    Publication date: April 15, 2010
    Applicant: GENENEWS CORPORATION
    Inventor: CHOONG-CHIN LIEW
  • METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF
    Publication number: 20110059447
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: April 9, 2010
    Publication date: March 10, 2011
    Applicant: GENENEWS CORPORATION
    Inventor: Choong-Chin Liew
  • METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF
    Publication number: 20110003298
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: April 9, 2010
    Publication date: January 6, 2011
    Applicant: GENENEWS CORPORATION
    Inventor: Choong-Chin Liew
  • Method of profiling gene expression in a healthy subject
    Publication number: 20110003294
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: April 9, 2010
    Publication date: January 6, 2011
    Applicant: GeneNews Corporation
    Inventor: Choong-Chin Liew
  • Method of profiling gene expression in a subject undergoing a treatment
    Publication number: 20110003295
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: April 9, 2010
    Publication date: January 6, 2011
    Applicant: GENENEWS CORPORATION
    Inventor: Choong-Chin Liew
  • METHOD FOR THE DETECTION OF GENE TRANSCRIPTS IN BLOOD AND USES THEREOF
    Publication number: 20110003297
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: April 9, 2010
    Publication date: January 6, 2011
    Applicant: GENENEWS CORPORATION
    Inventor: Choong-Chin Liew
  • Method of profiling gene expression in a subject having an infectious disease
    Publication number: 20110014614
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: April 9, 2010
    Publication date: January 20, 2011
    Applicant: GENENEWS CORPORATION
    Inventor: Choong-Chin Liew
  • METHOD OF PROFILING GENE EXPRESSION IN A SUBJECT HAVING COLORECTAL CANCER
    Publication number: 20130190197
    Abstract: The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and monitoring diseases using tissue-specific primers. The present invention also describes methods by which delineation of the sequence and/or quantitation of the expression levels of disease-associated genes allows for an immediate and accurate diagnostic/prognostic test for disease or to assess the effect of a particular treatment regimen.
    Type: Application
    Filed: August 13, 2012
    Publication date: July 25, 2013
    Applicant: GeneNews Corporation
    Inventor: Choong-Chin Liew
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