Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
Type:
Application
Filed:
March 7, 2007
Publication date:
September 6, 2007
Inventors:
Luc Chanteloup, Bruno Chauveau, Christina Corbin, Robert Dhal, Sonia Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
Type:
Application
Filed:
March 11, 2005
Publication date:
October 6, 2005
Inventors:
Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
Type:
Application
Filed:
June 4, 2004
Publication date:
November 4, 2004
Inventors:
Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
Abstract: The present invention relates to novel intermediates for the hemisynthesis of taxanes and to their processes of preparation. The compounds of the present invention include precursor compounds of taxane side chains.
Type:
Application
Filed:
April 18, 2001
Publication date:
June 6, 2002
Applicant:
Societe d'Etude et de Recherche en Ingenierie Pharmaceutique Seripharm
Inventors:
Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
Type:
Grant
Filed:
June 4, 2004
Date of Patent:
October 9, 2007
Assignee:
Societe d'etude et de Recherche en Ingenierie Pharmaceutique Seripharm
Inventors:
Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
Type:
Grant
Filed:
March 11, 2005
Date of Patent:
May 22, 2007
Assignee:
Societe d'etude et de Recherche en Ingenierie Pharmaceutique Seripharm
Inventors:
Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
Abstract: The present invention relates to novel intermediates for the hemisynthesis of taxanes and to their processes of preparation. The compounds of the present invention include precursor compounds of taxane side chains.
Type:
Grant
Filed:
April 18, 2001
Date of Patent:
November 30, 2004
Assignee:
Novasep
Inventors:
Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
Type:
Grant
Filed:
March 7, 2007
Date of Patent:
October 7, 2008
Assignee:
Societe d'Etude et de Recherche En Ingenierie Pharmaceutique-Seripharm
Inventors:
Luc Chanteloup, Bruno Chauveau, Christina Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
Abstract: The present invention relates to new intermediates for the semisynthesis of taxanes and their preparation processes. It relates to derivatives of oxazolidines or oxazolidinones, as well as to new derivatives of baccatine III. The general process for the synthesis of taxanes according to the invention enables to obtain a product such as PACLITAXEL in only five steps from products available in the market, compared to nine steps in general, for processes of the prior art.
Type:
Grant
Filed:
April 27, 1998
Date of Patent:
July 24, 2001
Assignee:
Societe d'Etude et de Recherche en Ingenierie Pharmaceutique
Seripharm
Inventors:
Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
Abstract: New processes for the selective protection of the 7-position of 7,10-dihydroxytaxane derivatives, using &bgr;-substituted-alkoxycarbonyl groups which are more hindered than 2,2,2-trichloroethoxycarbonyl, and which are capable of being removed by a &bgr;-elimination mechanism, and the new intermediates resulting from these processes. The new intermediates of the invention are useful for preparing taxol and analogs thereof.
Type:
Grant
Filed:
May 19, 1998
Date of Patent:
January 30, 2001
Assignee:
Societe d'Etude et de Recherche en Ingenierie Pharmaceutique
Seripharm
Inventors:
Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
Abstract: A fuel injector for an aircraft turbine engine includes a tubular body having an axis of elongation. A first longitudinal end configured to be supplied with fuel and a second longitudinal end configured to eject a jet of fuel. The body further includes an integrated purge-air circuit that has an internal cavity which is connected to air inlet orifices situated on the body and to at least one air outlet situated at said second end. Air-flow disruptors are provided, projecting into said cavity.
Type:
Application
Filed:
July 16, 2020
Publication date:
September 8, 2022
Applicant:
SAFRAN HELICOPTER ENGINES
Inventors:
Thomas Jean Olivier LEDERLIN, Denis Luc Alain CHANTELOUP, Simon Arthur MEILLEURAT
Abstract: A fuel injector for an aircraft turbine engine includes a tubular body having an axis of elongation. A first longitudinal end configured to be Supplied with fuel and a second longitudinal end configured to elect a jet of fuel. The body further includes an integrated purge-air circuit that has an internal cavity which is connected to air inlet orifices situated on the body and to at least one air outlet situated at said second end. Aire-flow disruptors are provided, projecting into said cavity.
Type:
Grant
Filed:
July 16, 2020
Date of Patent:
February 6, 2024
Assignee:
SAFRAN HELICOPTER ENGINES
Inventors:
Thomas Jean Olivier Lederlin, Denis Luc Alain Chanteloup, Simon Arthur Meilleurat
Abstract: A method and system for cooling turbine engine turbines, the system includes: at least one pair of parts to be cooled, the pair including a stator upstream from the rotor valve, and a sealing ring mounting a downstream movable blade rotor that is adjacent to the stator; a turbine casing; and an outlet path. The system further includes: at least one opening in the casing facing at least one part to be cooled; and an air circuit producing a forced convection in connection with the parts and at least one downstream outlet in the path so as to draw in and transport an ambient air flow.
Type:
Application
Filed:
December 20, 2010
Publication date:
October 11, 2012
Applicant:
TURBOMECA
Inventors:
Denis Luc, Alain Chanteloup, Manuel Philippe, Jean Pierre
Abstract: A laser welding head is configured to fasten under a focusing lens for focusing the laser and including at least one annular nozzle for injecting a protective gas, and a protective chamber for protecting the focusing lens with a transverse flow of air. The annular nozzle is arranged around an unobstructed optical axis passing through the laser welding head. The chamber for protecting the focusing lens with a transverse flow of air includes air admission and air exhaust in register with the air admission in a plane substantially perpendicular to said optical axis. The laser welding head is configured to be fastened against the focusing lens without any lateral opening between the focusing lens and the protective chamber. The head presents a distance of at least 100 mm between an outlet of the annular nozzle and the protective chamber.
Type:
Application
Filed:
December 16, 2013
Publication date:
June 30, 2016
Applicant:
TURBOMECA
Inventors:
Denis Luc, Alain CHANTELOUP, Jean Marc DUBOURDIEU, Olivier LAMAISON, Christian VALLY
Abstract: A laser welding head is configured to fasten under a focusing lens for focusing the laser and including at least one annular nozzle for injecting a protective gas, and a protective chamber for protecting the focusing lens with a transverse flow of air. The annular nozzle is arranged around an unobstructed optical axis passing through the laser welding head. The chamber for protecting the focusing lens with a transverse flow of air includes air admission and air exhaust in register with the air admission in a plane substantially perpendicular to said optical axis. The laser welding head is configured to be fastened against the focusing lens without any lateral opening between the focusing lens and the protective chamber. The head presents a distance of at least 100 mm between an outlet of the annular nozzle and the protective chamber.
Type:
Grant
Filed:
December 16, 2013
Date of Patent:
July 3, 2018
Assignee:
TURBOMECA
Inventors:
Denis Luc Alain Chanteloup, Jean Marc Dubourdieu, Olivier Lamaison, Christian Vally