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  • Publication number: 20070208185
    Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
    Type: Application
    Filed: March 7, 2007
    Publication date: September 6, 2007
    Inventors: Luc Chanteloup, Bruno Chauveau, Christina Corbin, Robert Dhal, Sonia Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Publication number: 20040220256
    Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
    Type: Application
    Filed: June 4, 2004
    Publication date: November 4, 2004
    Inventors: Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Publication number: 20050222089
    Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
    Type: Application
    Filed: March 11, 2005
    Publication date: October 6, 2005
    Inventors: Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Publication number: 20020068833
    Abstract: The present invention relates to novel intermediates for the hemisynthesis of taxanes and to their processes of preparation. The compounds of the present invention include precursor compounds of taxane side chains.
    Type: Application
    Filed: April 18, 2001
    Publication date: June 6, 2002
    Applicant: Societe d'Etude et de Recherche en Ingenierie Pharmaceutique Seripharm
    Inventors: Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Patent number: 7279586
    Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
    Type: Grant
    Filed: June 4, 2004
    Date of Patent: October 9, 2007
    Assignee: Societe d'etude et de Recherche en Ingenierie Pharmaceutique Seripharm
    Inventors: Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Patent number: 7220871
    Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: May 22, 2007
    Assignee: Societe d'etude et de Recherche en Ingenierie Pharmaceutique Seripharm
    Inventors: Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Patent number: 6825365
    Abstract: The present invention relates to novel intermediates for the hemisynthesis of taxanes and to their processes of preparation. The compounds of the present invention include precursor compounds of taxane side chains.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: November 30, 2004
    Assignee: Novasep
    Inventors: Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Patent number: 7432383
    Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: October 7, 2008
    Assignee: Societe d'Etude et de Recherche En Ingenierie Pharmaceutique-Seripharm
    Inventors: Luc Chanteloup, Bruno Chauveau, Christina Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Patent number: 6180802
    Abstract: New processes for the selective protection of the 7-position of 7,10-dihydroxytaxane derivatives, using &bgr;-substituted-alkoxycarbonyl groups which are more hindered than 2,2,2-trichloroethoxycarbonyl, and which are capable of being removed by a &bgr;-elimination mechanism, and the new intermediates resulting from these processes. The new intermediates of the invention are useful for preparing taxol and analogs thereof.
    Type: Grant
    Filed: May 19, 1998
    Date of Patent: January 30, 2001
    Assignee: Societe d'Etude et de Recherche en Ingenierie Pharmaceutique Seripharm
    Inventors: Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Patent number: 6265587
    Abstract: The present invention relates to new intermediates for the semisynthesis of taxanes and their preparation processes. It relates to derivatives of oxazolidines or oxazolidinones, as well as to new derivatives of baccatine III. The general process for the synthesis of taxanes according to the invention enables to obtain a product such as PACLITAXEL in only five steps from products available in the market, compared to nine steps in general, for processes of the prior art.
    Type: Grant
    Filed: April 27, 1998
    Date of Patent: July 24, 2001
    Assignee: Societe d'Etude et de Recherche en Ingenierie Pharmaceutique Seripharm
    Inventors: Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Publication number: 20120257954
    Abstract: A method and system for cooling turbine engine turbines, the system includes: at least one pair of parts to be cooled, the pair including a stator upstream from the rotor valve, and a sealing ring mounting a downstream movable blade rotor that is adjacent to the stator; a turbine casing; and an outlet path. The system further includes: at least one opening in the casing facing at least one part to be cooled; and an air circuit producing a forced convection in connection with the parts and at least one downstream outlet in the path so as to draw in and transport an ambient air flow.
    Type: Application
    Filed: December 20, 2010
    Publication date: October 11, 2012
    Applicant: TURBOMECA
    Inventors: Denis Luc, Alain Chanteloup, Manuel Philippe, Jean Pierre
  • Publication number: 20160184928
    Abstract: A laser welding head is configured to fasten under a focusing lens for focusing the laser and including at least one annular nozzle for injecting a protective gas, and a protective chamber for protecting the focusing lens with a transverse flow of air. The annular nozzle is arranged around an unobstructed optical axis passing through the laser welding head. The chamber for protecting the focusing lens with a transverse flow of air includes air admission and air exhaust in register with the air admission in a plane substantially perpendicular to said optical axis. The laser welding head is configured to be fastened against the focusing lens without any lateral opening between the focusing lens and the protective chamber. The head presents a distance of at least 100 mm between an outlet of the annular nozzle and the protective chamber.
    Type: Application
    Filed: December 16, 2013
    Publication date: June 30, 2016
    Applicant: TURBOMECA
    Inventors: Denis Luc, Alain CHANTELOUP, Jean Marc DUBOURDIEU, Olivier LAMAISON, Christian VALLY
  • Patent number: 10010976
    Abstract: A laser welding head is configured to fasten under a focusing lens for focusing the laser and including at least one annular nozzle for injecting a protective gas, and a protective chamber for protecting the focusing lens with a transverse flow of air. The annular nozzle is arranged around an unobstructed optical axis passing through the laser welding head. The chamber for protecting the focusing lens with a transverse flow of air includes air admission and air exhaust in register with the air admission in a plane substantially perpendicular to said optical axis. The laser welding head is configured to be fastened against the focusing lens without any lateral opening between the focusing lens and the protective chamber. The head presents a distance of at least 100 mm between an outlet of the annular nozzle and the protective chamber.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: July 3, 2018
    Assignee: TURBOMECA
    Inventors: Denis Luc Alain Chanteloup, Jean Marc Dubourdieu, Olivier Lamaison, Christian Vally
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