Search Patents
  • Publication number: 20090281069
    Abstract: The present invention relates to compounds of the formula; and their use in therapy.
    Type: Application
    Filed: April 10, 2007
    Publication date: November 12, 2009
    Inventors: Daniel Kaspar Baeschlin, Garry Fenton, Kenji Namoto, Nils Ostermann, Richard Sedrani, Finton Sirockin
  • Publication number: 20020016341
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic thioesters and ketones.
    Type: Application
    Filed: June 12, 2001
    Publication date: February 7, 2002
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Publication number: 20010041733
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic esters or amides.
    Type: Application
    Filed: June 14, 2001
    Publication date: November 15, 2001
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Publication number: 20010036947
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.
    Type: Application
    Filed: February 13, 2001
    Publication date: November 1, 2001
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Publication number: 20140155434
    Abstract: The present invention relates to a thermogelling pharmaceutical composition comprising local anaesthetics in base form and which is suitable for topical administration. The compositions further comprise a polyoxyethylene castor oil and one or more surfactants to obtain thermogelling characteristics.
    Type: Application
    Filed: February 4, 2014
    Publication date: June 5, 2014
    Applicant: Pharmanest AB
    Inventors: Mark Sundberg, Arne Brodin, Nils Kallberg
  • Patent number: 6187796
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule sulfonamides.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: February 13, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Patent number: 6274617
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic esters or amides.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: August 14, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Patent number: 7056935
    Abstract: This invention relates to methods of using neurotrophic compounds having an affinity for FKBP-type immunophilins to stimulate or promote neuronal growth or regeneration and to prevent neuronal degeneration.
    Type: Grant
    Filed: March 14, 2001
    Date of Patent: June 6, 2006
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Patent number: 6274602
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic thioesters and ketones.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: August 14, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Patent number: 6395758
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using small molecule carbamates and ureas.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: May 28, 2002
    Assignee: GPI Nil Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Patent number: 6376517
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using pipecolic acid derivatives.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: April 23, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Patent number: 6218424
    Abstract: This invention relates to neurotrophic, low molecular weight, small molecule heterocyclic ketone and thioester compounds, compositions containing the same, and the use of such compounds for treating neurological disorders, including physically damaged nerves and neurodegenerative diseases.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: April 17, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li
  • Patent number: 6399648
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using N-Oxides of heterocyclic esters, amides, thioesters, or ketones
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: June 4, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Patent number: 5990131
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule heterocyclic thioesters and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: August 1, 1997
    Date of Patent: November 23, 1999
    Assignee: Gpi Nil Holdings Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li
  • Patent number: 6333340
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance in an animal using small molecule sulfonamides.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: December 25, 2001
    Assignee: Gpi Nil Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Patent number: 6335348
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance in an animal, using pipecolic acid derivatives.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: January 1, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Patent number: 5968957
    Abstract: This invention relates to a method of using neurotrophic low molecular weight, small molecule piperidine and pyrrolidine sulfonamide compounds having an affinity for FKBP-type immunophilins, as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: February 23, 1998
    Date of Patent: October 19, 1999
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li, Joseph P. Steiner
  • Patent number: 6384056
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic thioesters and ketones.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: May 7, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Patent number: 5721256
    Abstract: This invention relates to a method of using neurotrophic low molecular weight, small molecule sulfonamide compounds having an affinity for FKBP-type immunophilins, as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: February 12, 1997
    Date of Patent: February 24, 1998
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li, Joseph P. Steiner
  • Patent number: 6245783
    Abstract: This invention relates to a method of using neurotrophic low molecular weight, small molecule sulfonamide compounds having an affinity for FKBP-type immunophilins, as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: October 18, 1999
    Date of Patent: June 12, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li, Joseph P. Steiner