Search Patents
  • LEGAL AUTHENTICATION MESSAGE CONFIRMATION SYSTEM AND METHOD
    Publication number: 20160021534
    Abstract: Provided is a system for preventing personal information leakage and, more particularly, related to a legal authentication message confirmation system and method which enables a user to identify whether an authentication message transmitted to the user's mobile communication terminal during user authentication originates from a trusted source, thereby preventing damage caused by pharming, smishing, and the like, such as personal information leakage and small sum payment fraud.
    Type: Application
    Filed: March 20, 2014
    Publication date: January 21, 2016
    Inventor: Ki-Yoong HONG
  • C1 Inhibitor produced in the milk of transgenic non-human mammals
    Patent number: 7067713
    Abstract: The invention provides transgenic nonhuman mammals expressing C1 inhibitor in their milk. The C1 inhibitor is useful in treating patients with hereditary angioedema or patients requiring immunosuppression.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: June 27, 2006
    Assignee: Pharming Intellectual Property B.V.
    Inventors: Jan Henricus Nuijens, Henricus Antonius Van Veen, Frank Robert Pieper, Joris Jan Heus
  • Use of C1 Inhibitor for the Prevention of Ischemia-Reperfusion Injury
    Publication number: 20080305993
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Application
    Filed: December 19, 2006
    Publication date: December 11, 2008
    Applicant: Pharming Intellectual Property B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • Use Of C1 Inhibitor For The Prevention Of Ischemia-Reperfusion Injury
    Publication number: 20130244941
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Application
    Filed: February 25, 2013
    Publication date: September 19, 2013
    Applicant: PHARMING INTELLECTUAL PROPERTY B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • Production of collagen in the milk of transgenic mammals
    Publication number: 20100305039
    Abstract: The invention provides transgenic nonhuman mammals capable secreting exogenous procollagen or collagen into their milk. The mammals are healthy and capable of producing procollagen or collagen at high levels, usually in trimeric form. Suitable transgenes for incorporation into the mammals are also provided.
    Type: Application
    Filed: November 10, 2008
    Publication date: December 2, 2010
    Applicants: Pharming Intellectual Property B.V., Cohesion Technologies, Inc.
    Inventors: Costas N. Karatzas, Frank Pieper, Ineke De Wit, Richard Berg, Gerard Platenburg, Paul David Toman
  • MODIFIED PLANT ENDOSPERM SPECIFIC PROMOTER AND USE THEREOF
    Publication number: 20230383302
    Abstract: Provided is a modified rice endosperm-specific promoter, which has a sequence as shown in any one of SEQ ID. NOs. 1 to 5. The EnhGt13a promoter as shown in SEQ ID NO. 2 drives GUS activity in vitro and mediates the expression of foreign proteins in rice endosperm cells, which is significantly higher than that of the unmodified Gt13a promoter. The promoter can be applied to the fields of improving seed quality, molecular pharming, etc.
    Type: Application
    Filed: August 17, 2021
    Publication date: November 30, 2023
    Inventors: Daichang YANG, Kunpeng LI
  • Use of C1 inhibitor for the prevention of ischemia-reperfusion injury
    Patent number: 9211318
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: December 15, 2015
    Assignee: PHARMING INTELLECTUAL PROPERTY B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • Legal authentication message confirmation system and method
    Patent number: 9426655
    Abstract: Provided is a system for preventing personal information leakage and, more particularly, related to a legal authentication message confirmation system and method which enables a user to identify whether an authentication message transmitted to the user's mobile communication terminal during user authentication originates from a trusted source, thereby preventing damage caused by pharming, smishing, and the like, such as personal information leakage and small sum payment fraud.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: August 23, 2016
    Assignee: SECUVE CO., LTD.
    Inventor: Ki-Yoong Hong
  • USE OF C1 INHIBITOR FOR THE PREVENTION OF ISCHEMIA-REPERFUSION INJURY
    Publication number: 20120088728
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Application
    Filed: October 11, 2011
    Publication date: April 12, 2012
    Applicant: PHARMING INTELLECTUAL PROPERTY B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • Use of C1 inhibitor for the prevention of ischemia-reperfusion injury
    Patent number: 8071532
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: December 6, 2011
    Assignee: Pharming Intellectual Property B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • Fibrinogen from transgenic animals
    Publication number: 20070219352
    Abstract: The present invention provides a method for the part purification of fibrinogen from milk, the method comprising the transfer of protease enzyme which is present in the milk, into the whey phase with the removal or partition of fibrinogen into another phase of the milk. The present invention also provides a method for obtaining fibrinogen from a fluid, the method comprising: a) contacting the fluid with a hydrophobic interaction chromatography resin under conditions where the fibrinogen binds to the resin; and b) removing the bound protein by means of elution.
    Type: Application
    Filed: April 9, 2007
    Publication date: September 20, 2007
    Applicant: Pharming Intellectual Property BV
    Inventors: Graham McCreath, Michael Udell
  • COMPOSITE MATERIAL
    Publication number: 20100143490
    Abstract: The present invention provides a composite material comprising lactoferrin and a bioactive glass. The invention also relates to pharmaceutical compositions containing the composite material. Further aspects of the invention relate to the use of the composite material of the for treating a wound, treating or preventing bacterial or viral infections in a wound, preventing viral transmission, regenerating bone, treating osteoporosis, preventing or alleviating bleeding in a wound, sterilising a wound and/or controlling haemorrhaging.
    Type: Application
    Filed: August 21, 2007
    Publication date: June 10, 2010
    Applicants: NOVA THERA LIMITED, PHARMING GROUP NV
    Inventors: Gareth Roberts, Robert Daniels, Xiaobin Zhao, Ian Thompson
  • COMPOSITE MATERIAL
    Publication number: 20100136131
    Abstract: The present invention provides a composite material comprising fibrinogen or fibrin, or a mixture thereof, and a bioactive glass. The invention also relates to wound dressings and pharmaceutical compositions containing the composite material. Further aspects of the invention relate to the use of the composite material of the for treating a wound, treating or preventing bacterial infections in a wound, preventing or alleviating bleeding in a wound, sterilising a wound, controlling haemorrhaging, increasing the rate of coagulation of blood and/or activating a coagulation system in a wound.
    Type: Application
    Filed: August 21, 2007
    Publication date: June 3, 2010
    Applicants: NOVATHERMA LIMITED, PHARMING GROUP NV
    Inventors: Gareth Roberts, Robert Daniels, Xiaobin Zhao, Ian Thompson
  • Use of C1 inhibitor for the prevention of ischemia-reperfusion injury
    Patent number: 8415288
    Abstract: The present invention relates to the therapeutic and prophylactic use of C1 inhibitor for preventing, reducing and treating ischemia and reperfusion injury. The C1 inhibitor of the present invention is still therapeutically effective when administered after an ischemic period and reperfusion and therefore particularly useful for unforeseen occurrences of ischemic reperfusion such as e.g. a stroke.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: April 9, 2013
    Assignee: Pharming Intellectual Property B.V.
    Inventors: Maurice Mannesse, Johannes Henricus Nuijens, Frank Pieper, Maria Grazia De Simoni, Gijsbertus Johannes Ziere
  • Lysosomal proteins produced in the milk of transgenic animals
    Publication number: 20040003421
    Abstract: The invention provides transgenic nonhuman mammals producing phosphorylated lysosomal proteins in their milk, and methods of generating the same. Phosphorylation occurs at the 6′ position of a mannose side chain residue. Also provided are methods of purifying lysosomal proteins from milk, and incorporating the proteins into pharmaceutical compositions for use in enzyme replacement therapy.
    Type: Application
    Filed: January 23, 2003
    Publication date: January 1, 2004
    Applicant: Pharming B.V.
    Inventors: Arnold J.J. Reuser, Ans T. Van der Ploeg, Frank R. Pieper, Martin Ph. Verbeet
  • Production of collagen in the milk of transgenic mammals
    Patent number: 6713662
    Abstract: The invention provides transgenic nonhuman mammals capable secreting exogenous procollagen or collagen into their milk. The mammals are healthy and capable of producing procollagen or collagen at high levels, usually in trimeric form. Suitable transgenes for incorporation into the mammals are also provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 30, 2004
    Assignees: Pharming Intellectual Property B.V., Cohesion Technologies
    Inventors: Costas N. Karatzas, Frank Pieper, Ineke De Wit, Richard Berg, Gerard Platenburg, Paul David Toman
  • Modified plant endosperm specific promoter and use thereof
    Patent number: 11913002
    Abstract: Provided is a modified rice endosperm-specific promoter, which has a sequence as shown in any one of SEQ ID. NOs. 1 to 5. The EnhGt13? promoter as shown in SEQ ID NO. 2 drives GUS activity in vitro and mediates the expression of foreign proteins in rice endosperm cells, which is significantly higher than that of the unmodified Gt13? promoter. The promoter can be applied to the fields of improving seed quality, molecular pharming, etc.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: February 27, 2024
    Assignee: WUHAN HEALTHGEN BIOTECHNOLOGY CORP.
    Inventors: Daichang Yang, Kunpeng Li
  • Pesticides
    Publication number: 20070248699
    Abstract: The invention provides the use of loquat kernel to kill, inactivate or repel pests, in particular nematodes. Also provided is a method of killing, inactivating or repelling nematodes, which method comprises providing loquat kernel and applying the loquat kernel to the nematodes or to an area where the nematodes are likely to exist or to an area to where the nematodes are expected to move. The invention further provides a pesticide comprising loquat kernel and a pesticidally acceptable solvent, carrier, excipient or diluent; and a method of producing a pesticide, which method comprises providing ground, chopped, freeze dried or spray dried loquat kernel.
    Type: Application
    Filed: February 7, 2005
    Publication date: October 25, 2007
    Applicant: PHARMING LTD.
    Inventors: Ivo Baekelmans, Ron Brown, Irene Mueller-Harvey
  • Phenylalanine-free protein and DNA coding therefor
    Patent number: 6495344
    Abstract: A DNA molecule coding for a food protein, such as ovalbumin or casein, modified so that the codons for phenylalanine have been omitted or replaced by codons for one or more other metabolisable amino acids. Also a modified edible protein coded for by such a DNA molecule. Such modified proteins are useful in the nutrition of patients suffering from phenylketonuria.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: December 17, 2002
    Assignee: Pharming Holding N. V.
    Inventors: Noel Gordon Carr, Nicholas Harold Mann
  • METHOD OF CONTROLLING ACCESS TO AN INTERNET-BASED APPLICATION
    Publication number: 20140230038
    Abstract: A novel method of dealing with the problem of phishing, pharming, key-logging and man-in-the-middle attacks on internet-based applications which require the application (3) (such as an internet banking website) by the simple transmission of a command via the internet to allow access to the internet-based application (3) whenever the user wishes to access the application, and by transmitting a command via the internet to deny access to the internet-based application at all other times, to present unauthorized access by any unscrupulous parties.
    Type: Application
    Filed: February 16, 2012
    Publication date: August 14, 2014
    Applicant: E-LOCK CORPORATION SDN. BHD.
    Inventors: Chik Weng Leong, Chee Ho Lau, Yuen Len Kong, Tau Wei Phang, Hoon Sin Cheong
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