Abstract: Disclosed are compounds having Formula (I) and the compositions and methods thereof for treating or preventing a viral infection mediated at least in part by a virus in the Flaviviridae family of viruses, wherein A, R2, m, R, V, W, T, Z, R1, Y, and p are disclosed herein.
Type:
Grant
Filed:
December 12, 2006
Date of Patent:
September 29, 2009
Assignee:
SmithKline Beecham Corporation
Inventors:
Franz Ulrich Schmitz, Christopher Don Roberts, Ali Dehghani Mohammad Abadi, Ronald Conrad Griffith, Martin Robert Leivers, Irina Slobodov, Roopa Rai
Abstract: A plurality of data storage modules form a library, with a directory archive maintaining a directory of the information contained on each data storage module (file server application) or on the storage modules retained in the library (volume server application). A plurality of interface computers are coupled to a plurality of host computers for receiving data and for generating request signals to access the library. In response to a received request signal, the directory archive locates a data storage module and generates a location output signal. A control computer receives the location output signal and generates a media access signal for causing the data storage module to be loaded into a selected data recorder. An input/output data channel couples the interface computer generating the access request signal to the selected data recorder for reading or writing an entire volume of information or selected file information to/from the data storage module.
Type:
Grant
Filed:
November 12, 1993
Date of Patent:
April 2, 1996
Assignee:
E-Systems, Inc.
Inventors:
Charles W. Martin, Fredrick S. Reid, Gary L. Forbus, Steve M. Adams, C. Patrick Shannon, Eric A. Pirpich
Abstract: A skin is applied to a ceramic honeycomb. The skin is formed by applying a skin-forming composition and drying it. The skin-forming composition includes a carrier liquid, colloidal silica and/or colloidal alumina, and an inorganic filler. The filler includes an inorganic fiber. The filler may contain low aspect ratio particles that have the same or nearly the same CTE as the inorganic fiber. The filler may include a small proportion of a low aspect ratio filler particle that has a different CTE than the inorganic fiber.
Type:
Grant
Filed:
June 24, 2010
Date of Patent:
May 12, 2015
Assignee:
Dow Global Technologies LLC
Inventors:
Jun Cai, Aleksander J. Pyzik, Michael T. Malanga, Kwanho Yang, Steve J. Martin
Abstract: A mass data storage unit includes a plurality of first data storage modules that form a mass information storage library, a data directory archive for maintaining a directory of the information contained on each data storage module, and data record/playback modules for receiving any selected any data storage module in the mass storage library. A plurality of interface computers are coupled to a plurality of host computers for receiving data and for generating request signals to access information stored in the mass storage library. A file directory is coupled to the interface computers and the data directory archive for receiving the request signals, locating in the data directory archive the address containing the stored information and generating a data address location output signal for the stored information.
Type:
Grant
Filed:
April 12, 1993
Date of Patent:
May 2, 1995
Assignee:
E-Systems, Inc.
Inventors:
Charles W. Martin, Frederick S. Reid, Gary L. Forbus, Steve M. Adams, C. Pat Shannon, Eric A. Pirpich
Abstract: The xylanase is characterized by several partial amino acid sequences and is immunoreactive with an antibody raised against a purified xylanase derived from Humicola insolens, DSM 1800. This xylanase preparation is practically free of cellulase xylanase and is well suited for treatment of paper pulp, as a baking agent and as an additive to fodder.
Type:
Grant
Filed:
September 21, 1993
Date of Patent:
March 11, 1997
Assignee:
Novo Nordisk A/S
Inventors:
Martin Schulein, Torben Halkier, Hans P. Heldt-Hansen, Henrik Dalb.o slashed.ge, Lars S. Pedersen
Abstract: Description tables can be linked to a kernel to form a device driver. The description tables can be device description tables and adapter description tables. The kernel is operating system dependent. The description tables are operating system independent and can be linked to other kernels for other operating systems. A library of kernels for different operating systems can share a common set of kernel requests.
Type:
Grant
Filed:
September 30, 1993
Date of Patent:
October 17, 1995
Assignee:
Iomega Corporation
Inventors:
Phillip M. Adams, Larry W. Holmstron, Steve A. Jacob, Steven H. Powell, Robert F. Condie, Martin L. Culley
Abstract: A method for converting between relatively dose field rates of perhaps 60 Hz and 59.94 Hz, monitors the phase difference between input and output field rates. Initially, output fields are created by synchronising input fields. As the measured phase passes a threshold, the method switches to interpolation mode for a short, fixed interval and then returns to synchronization. The method offers much of the sharpness associated with simple synchronization but avoids the visible discontinuities of field drops or repeats.
Type:
Grant
Filed:
February 1, 1995
Date of Patent:
March 31, 1998
Assignee:
Snell & Wilcox Ltd.
Inventors:
Peter Wilson, Martin Weston, Steve Dabner
Abstract: A motor control system employing a single Hall sensor 2 providing a position feedback signal to a control circuit 10 is disclosed. The control circuit includes a tach counter circuit 12, a ramp mode circuit 14, an interpolation circuit 16, and a commutation logic circuit 18. Drive signals are output to the motor windings by the commutation logic circuit 18. The control state defining the drive signals is advanced on the basis of the estimated rotor position. The estimate of the rotor position is determined by linearly interpolating between Hall signal transitions.
Type:
Grant
Filed:
August 25, 1997
Date of Patent:
April 18, 2000
Assignee:
Iomega Corporation
Inventors:
Steve Rabin, Kirk D. Hanson, Mark W. Perona
Abstract: Each of a series of parallel stalls in dairy parlor includes a swinging entry gate having on one side of its hinge axis a major portion, normally blocking the stall mouth. A minor portion of the gate, on the other side of its hinge axis, protrudes partially across the mouth of a neighboring stall. The stall cannot be entered by an animal until the gate has been opened by the entry of a preceding animal into the neighboring stall. The gate has an effective width substantially greater than the stall width.
Abstract: A mass data storage unit includes a plurality of first data storage modules that form a mass information storage library, a data directory archive for maintaining a directory of the information contained on each data storage module, and data record/playback modules for receiving any selected data storage module in the mass storage library. A plurality of interface computers are coupled to a plurality of host computers for receiving data and for generating request signals to access information stored in the mass storage library. A file directory is coupled to the interface computers and the data directory archive for receiving the request signals, locating in the data directory archive the address containing the stored information and generating a data address location output signal for the stored information.
Type:
Grant
Filed:
November 1, 1989
Date of Patent:
May 25, 1993
Assignee:
E-Systems, Inc.
Inventors:
Charles W. Martin, Frederick S. Reid, Gary L. Forbus, Steve M. Adams, C. Pat Shannon, Eric A. Pirpich
Abstract: A method for equipment lease processing and management, using a network-based system and at least one client system configured to communicate with the network-based system. The method includes providing a lease application on the network-based system, the lease application configured to be completed using the client system, and submitted to the network using the client system. The method also includes processing a completed lease application using the network based system, and displaying on the client system the results of said processing of the completed lease application, using the network-based system.
Type:
Application
Filed:
December 31, 2001
Publication date:
July 3, 2003
Inventors:
Theodore W. Hine, Susan Bauer, Martin Lewandowski, Selma Lower, Craig Cochran, Kirby Miller, Mark Jorgensen, Steve Choban, Jodi Chrisman
Abstract: A method for analyzing a gaseous electronegative species comprises the steps of providing an analysis chamber; providing an electric field of known potential within the analysis chamber; admitting into the analysis chamber a gaseous sample containing the gaseous electronegative species; providing a pulse of free electrons within the electric field so that the pulse of free electrons interacts with the gaseous electronegative species so that a swarm of electrically charged particles is produced within the electric field; and, measuring the mobility of the electrically charged particles within the electric field.
Type:
Grant
Filed:
September 27, 1991
Date of Patent:
February 2, 1993
Assignee:
Martin Marietta Energy Systems, Inc.
Inventors:
Steve L. Allman, Chung-Hsuan Chen, Fang C. Chen
Abstract: A method according to one embodiment includes determining, by a server, a location of a door in an architectural drawing and a room function of a room secured by the door based on an analysis of the architectural drawing, determining, by the server, proper access control hardware to be installed on the door based on the room function, a category of access control hardware, and a predictive machine learning model associated with the category of access control hardware, and generating, by the server, a specification based on the determined proper access control hardware.
Type:
Application
Filed:
July 13, 2021
Publication date:
November 4, 2021
Inventors:
Robert S. Prostko, Robert C. Martens, Nick Heitzman, Kristin Day, Martin Madsen, Jason Kornaker, Daniel Langenberg, Brian C. Eickhoff, Scott Baxter, Joseph W. Baumgarte, Benjamin Hopkins, Steve J. Kottlowski, Jacob Scheib
Abstract: A method according to one embodiment includes determining, by a server, a location of a door in an architectural drawing and a room function of a room secured by the door based on an analysis of the architectural drawing, determining, by the server, proper access control hardware to be installed on the door based on the room function, a category of access control hardware, and a predictive machine learning model associated with the category of access control hardware, and generating, by the server, a specification based on the determined proper access control hardware.
Type:
Application
Filed:
May 29, 2019
Publication date:
December 5, 2019
Inventors:
Robert S. Prostko, Robert C. Martens, Nick Heitzman, Kristin Day, Martin Madsen, Jason Kornaker, Daniel Langenberg, Brian C. Eickhoff, Scott Baxter, Joseph W. Baumgarte, Benjamin Hopkins, Steve J. Kottlowski, Jacob Scheib
Abstract: A bi-directional, redundant, optical transport system is configured to provide a non-blocking, bi-directional, multi-channel, protocol independent optical transport system for the simultaneous transfer of digital, analog, and discrete data between a plurality data terminal equipment. The optical transport system includes a light transmission line for transmitting light bi-directionally and a plurality of nodes, connected in series by the light transmission line for receiving, extracting and passing signal light.
Type:
Grant
Filed:
January 29, 1998
Date of Patent:
April 27, 1999
Assignee:
Lockheed Martin Corporation
Inventors:
Steve W. Braun, Henri Hodara, John J. Soderberg, G. Allan Whittaker
Abstract: This invention relates to an enzyme which exhibits cellulase activity and is producible by a strain of Bacillus sp., NCIMB 40250, or a related Bacillus sp. strain, or a derivative of said cellulase. This invention also relates to an enzyme which comprises a core region derived from an endoglucanase combined with a cellulose-binding domain derived from another cellulase, or which comprises a core region derived from another cellulase combined with a cellulose-binding domain derived from an endoglucanase.
Type:
Grant
Filed:
July 27, 1992
Date of Patent:
June 29, 1999
Assignee:
Novo Nordisk A/S
Inventors:
Per Lin.ang. J.o slashed.rgensen, Martin Schulein, Christian Hansen
Abstract: An electric pulse generator includes a driver having an outer surface, a receiver, and one or more piezoelectric elements disposed between and in electrical contact with the driver and the receiver. The electric pulse generator further includes an explosive material disposed on the outer surface of the driver. A method of making an electrical pulse generator includes providing one or more piezoelectric elements, a driver, a receiver, and an explosive material and operably associating the explosive material with an outer surface of the driver. The method further includes electrically coupling the one or more piezoelectric elements between the driver and the receiver.
Type:
Grant
Filed:
June 9, 2005
Date of Patent:
April 6, 2010
Assignee:
Lockheed Martin Corporation
Inventors:
Steve E. Calico, Shad L. Holt, James C. Dickens, John W. Walter
Abstract: Apparatus for detecting an electronegative species comprises an analysis chamber, an inlet communicating with the analysis chamber for admitting a sample containing the electronegative species and an ionizable component, a radioactive source within the analysis chamber for emitting radioactive energy for ionizing a component of the sample, a proportional electron detector within the analysis chamber for detecting electrons emitted from the ionized component, and a circuit for measuring the electrons and determining the presence of the electronegative species by detecting a reduction in the number of available electrons due to capture of electrons by the electronegative species.
Type:
Grant
Filed:
July 2, 1991
Date of Patent:
March 8, 1994
Assignee:
Martin Marietta Energy Systems, Inc.
Inventors:
Steve L. Allman, Fang C. Chen, Chung-Hsuan Chen
Abstract: A method according to one embodiment includes determining, by a server, a location of a door in an architectural drawing and a room function of a room secured by the door based on an analysis of the architectural drawing, determining, by the server, proper access control hardware to be installed on the door based on the room function, a category of access control hardware, and a predictive machine learning model associated with the category of access control hardware, and generating, by the server, a specification based on the determined proper access control hardware.
Type:
Grant
Filed:
July 13, 2021
Date of Patent:
May 6, 2025
Assignee:
Schlage Lock Company LLC
Inventors:
Robert S. Prostko, Robert C. Martens, Nick Heitzman, Kristin Day, Martin Madsen, Jason Kornaker, Daniel Langenberg, Brian C. Eickhoff, Scott Baxter, Joseph W. Baumgarte, Benjamin Hopkins, Steve J. Kottlowski, Jacob Scheib
Abstract: A bi-directional, redundant, optical transport system is configured to provide a non-blocking, bi-directional, multi-channel, protocol independent optical transport system for the simultaneously transfer of digital, analog, and discrete data between a plurality data terminal equipment. The optical transport system includes a light transmission line for transmitting light bi-directionally and a plurality of nodes, connected in series by the light transmission line for receiving, extracting and passing signal light.
Type:
Grant
Filed:
March 29, 2001
Date of Patent:
April 20, 2010
Assignee:
Lockheed Martin Corporation
Inventors:
Steve W. Braun, Henri Hodara, John J. Soderberg, G. Allan Whittaker