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  • Method for isolation of silymarin from seeds
    Patent number: 7318940
    Abstract: This invention relates to a method for the isolation of silymarin from silybum marianum seeds without precooling wherein the ground seeds are defatted using a hydrocarbon solvent, followed by extraction with a nontoxic medium polarity solvent, purification of the dried extract and drying of the crystals thus obtained.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: January 15, 2008
    Inventor: Vladimir Leko
  • Method for isolation of sylimarin from sylibum marianum seeds
    Publication number: 20060159785
    Abstract: This invention relates to a method for isolation of sylimarin from silybum marianum seeds wherein the seeds are grinded without precooling. The follow defatting with hydrocarbon solvent, extraction with medium polarity solvent, removal of water from evaporating residue lagged after extraction, purification of dry extract, separation, washing and drying of obtained crystales.
    Type: Application
    Filed: September 5, 2003
    Publication date: July 20, 2006
    Inventor: Vladimir Leko
  • Composition for protection and regeneration of structure and function of the liver
    Publication number: 20050003028
    Abstract: The composition of herbal origin in which the active substance is sylimarin, characterized by the fact that, apart from the active substance which in the composition can be present in isolated form or like a component of St. Mary thistle plant, also contains the following components that are in synergic relation with the active substance: Millefolii flos—yarrow flower Taraxaci radix—dandelion root Menthae piperitae folium—peppermint leaf Cardui mariae folium—St. Mary thistle leaf Helichrysi flos—Menyanthes trifoliata folium—buckbean leaf.
    Type: Application
    Filed: June 28, 2004
    Publication date: January 6, 2005
    Inventor: Vladimir Leko
  • Composition for protection and regeneration of structure and function of the liver
    Patent number: 7172774
    Abstract: The composition of herbal origin in which the active substance is sylimarin, characterized by the fact that, apart from the active substance which in the composition can be present in isolated form or like a component of St. Mary thistle plant, also contains the following components that are in synergic relation with the active substance: Millefolii flos—yarrow flower Taraxaci radix—dandelion root Menthae piperitae folium—peppermint leaf Cardui mariae folium—St. Mary thistle leaf Helichrysi Menyanthes trifoliata folium—buckbean leaf.
    Type: Grant
    Filed: June 28, 2004
    Date of Patent: February 6, 2007
    Inventor: Vladimir Leko
  • Process and product extracted from herbal composition useful in controlling diabetes mellitus type II
    Publication number: 20030206976
    Abstract: An active substance is extracted from an herbal composition which comprises: Centaurii umbellatum, Gentianaceae (centaury plant), Teraxacum officinale, Asteraceae (dandelion root), Juniperi communis L, Cupresaceae (juniper berry), Urticae dioica L, Urticeae (nettle plant), Urticae dioica L, Urticaceae (nettle root), Cichorium intybus L, Cichoriaceae (chicory root), Morus nigra L, Moraceae, (mulberry leaf), Achilleae millefolium L, Asteraceae (yarrow flower), Vaccinium myrtillus L, Ericaceae (bilberry leaf), Phaseolus vulgaris L, Fabaceae (bean pods), Valeriana officinalis L, Valerlanaceae (Valerian root). The active substance is used in the manufacture of pharmaceutical compositions used in connection with control of diabetes mellitus type II.
    Type: Application
    Filed: April 30, 2003
    Publication date: November 6, 2003
    Inventor: Vladimir Leko
  • Herbal composition and medicament against diabetes mellitus type II manufactured thereof
    Patent number: 6576270
    Abstract: The invention relates to the herbal composition which consists of: Centaurii umbellatum, Gentianaceae (centaury plant), Teraxacum officinale, Asteraceae (dandelion root), Juniperi communis L, Cupresaceae (juniper berry), Urticae dioica L, Urticeae (nettle plant), Urticae dioica L, Urticaceae (nettle root), Cichorium intybus L, Cichoriaceae (chicory root), Morus nigra L, Moraceae, (mulberry leaf), Achilleae millefolium L, Asteraceae (yarrow flower), Vaccinium myrtillus L, Ericaceae (bilberry leaf), Phaseolus vulgaris L, Fabaceae (bean pods), Valeriana officinalis L, Valerlanaceae (Valerian root).
    Type: Grant
    Filed: September 11, 2001
    Date of Patent: June 10, 2003
    Inventor: Vladimir Leko
  • Process and product extracted from herbal composition useful in controlling diabetes mellitus type II
    Patent number: 7056539
    Abstract: An active substance is extracted from an herbal composition which comprises: Centaurii umbellatum, Gentianaceae (centaury plant), Teraxacum officinale, Asteraceae (dandelion root), Juniperi communis L, Cupresaceae (juniper berry), Urticae dioica L, Urticeae (nettle plant), Urticae dioica L, Urticaceae (nettle root), Cichorium intybus L, Cichoriaceae (chicory root), Morus nigra L, Moraceae, (mulberry leaf), Achilleae millefolium L, Asteraceae (yarrow flower), Vaccinium myrtillus L, Ericaceae (bilberry leaf), Phaseolus vulgaris L, Fabaceae (bean pods), Valeriana officinalis L, Valerlanaceae (Valerian root). The active substance is used in the manufacture of pharmaceutical compositions used in connection with control of diabetes mellitus type II.
    Type: Grant
    Filed: April 30, 2003
    Date of Patent: June 6, 2006
    Inventor: Vladimir Leko
  • Herbal composition and medicament against diabetes mellitus type II manufactured thereof
    Publication number: 20020102315
    Abstract: The invention refers to the herbal composition which consists of: the plant of centaury (Centauri herba) 12.3% by wt., the root of dandelion (Teraxaci radix) 9.7% by wt., the fruit of juniper (Juniperi communis fructus) 6.2% by wt., the plant of nettle (Urticae herba) 7.4% by wt., the root of nettle (Urticae radix) 7.0% by wt., the root of chicory (Cichorii radix) 17.7% by wt., the leaf of black mulberry (Morus nigra folium) 7.4% by wt., the flower of yarrow (Achilleae millefolii flos) 3.5% by wt., the leaf of bilberry (Vaccinii myrtilli folium) 6.6% by wt., the pod of beans (Phaseoli fructus sine semeni) 14.4% by wt., and the root of valerian (Valerianae officinalis radix) 7.8% by wt., and to the medicament against diabetes mellitus type II obtained from it. The medicament is anticipated to be administered perorally in form of tea, a tincture and a pill.
    Type: Application
    Filed: September 11, 2001
    Publication date: August 1, 2002
    Inventor: Vladimir Leko
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