Search Patents
  • SYSTEM FOR CONTROLLING CONTAINER DATA CENTERS
    Publication number: 20140257524
    Abstract: A system for controlling container data centers (CDCs) includes a number of CDC groups, a number of slave monitoring systems, and a master monitoring system. Each CDC group includes a number of CDCs. Each slave monitoring system is connected to the CDCs of one CDC group via a network. Each slave monitoring system receives and processes data transmitted from the CDCs connected to the slave monitoring system, and transmits the processed data to the master monitoring system via the network. The master monitoring system receives the processed data from the slave monitoring systems, responds to user input to receive settings for controlling operation of the plurality of CDCs, and transmits the settings to the plurality of slave monitoring systems. The slave monitoring system transmit the settings to the CDCs connected to the slave monitoring systems. Each CDC operates according to the settings input by the user.
    Type: Application
    Filed: July 16, 2013
    Publication date: September 11, 2014
    Inventors: SHIH-CHIEH CHEN, CHIH-HUNG CHANG
  • PLACEMENT OF CONTAINERIZED APPLICATIONS IN A NETWORK FOR EMBEDDED CENTRALIZED DISCOVERY CONTROLLER (CDC) DEPLOYMENT
    Publication number: 20240031221
    Abstract: System and method embodiments for placement of Centralized Discovery Controller (CDC) services on a switching network fabric are disclosed. Nodes on the switching network fabric are categorized into leader nodes, e.g., spine switches, and follower nodes, e.g., leaf switches. The CDC services are divided into centralized CDC services and distributed CDC services, which has direct connections to endpoints for seamless horizontal scaling of endpoints. The centralized CDC services are placed on a leader node and the distributed CDC services are placed among the follower nodes. Operations of the CDC services are monitored. In case of a node failure, CDC services deployed on the failed node are moved or transferred to one or more other nodes that have the same role as the failed node. Implementation of the CDC service placement embodiments enables seamless horizontal scaling for endpoints and provides capability for more visibility and monitoring of endpoint.
    Type: Application
    Filed: July 20, 2022
    Publication date: January 25, 2024
    Applicant: DELL PRODUCTS L.P.
    Inventors: Balaji RAJAGOPALAN, Pawan Kumar SINGAL, Joseph LaSalle WHITE, Charles PARK, Ning ZHUANG, Sreejith SETHUMADHAVAN, Dhanunjayareddy MADHANA
  • CLOCK RELATIONSHIP BASED RE-CONVERGENCE ANALYSIS
    Publication number: 20240086602
    Abstract: A clock relationship based re-convergence analysis method includes receiving, by a processing device, a register-transfer level (RTL) description of a design relating to an integrated circuit (IC). The method further includes identifying one or more clock domain crossing (CDC) synchronizers in the RTL description of the design, and generating a levelized topological abstract graph (LTAG) including a network of nodes. Each node includes a CDC synchronizer. The method further includes traversing the LTAG starting from a first output of the one or more CDC synchronizers, and responsive to determining that a first CDC synchronizer of the one or more CDC synchronizers is converging with a second CDC synchronizer, identifying a first potential convergence violation associated with the first CDC synchronizer and the second CDC synchronizer.
    Type: Application
    Filed: August 17, 2023
    Publication date: March 14, 2024
    Inventors: Anchit JAIN, Deepak AHUJA, Paras Mal JAIN
  • Placement of containerized applications in a network for embedded centralized discovery controller (CDC) deployment
    Patent number: 12261740
    Abstract: System and method embodiments of centralized discovery controller (CDC) services on a switching network fabric are disclosed. Nodes on the switching network fabric are categorized into leader nodes, e.g., spine switches, and follower nodes, e.g., leaf switches. The CDC services may be divided into centralized CDC services and distributed CDC services, which have direct connections to endpoints for seamless horizontal scaling of endpoints. The centralized CDC services may be placed on a leader node, and the distributed CDC services may be placed among the follower nodes. Operations of the CDC services may be monitored. In case of a node failure, CDC services deployed on the failed node may be moved or transferred to one or more other nodes that have the same role as the failed node. Implementations of the CDC service placement embodiments enable seamless horizontal scaling for endpoints and provide capability for more visibility and monitoring of endpoint.
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: March 25, 2025
    Assignee: DELL PRODUCTS L.P.
    Inventors: Balaji Rajagopalan, Pawan Kumar Singal, Joseph Lasalle White, Charles Park, Ning Zhuang, Sreejith Sethumadhavan, Dhanunjayareddy Madhana
  • Placement of containerized applications in a network for embedded centralized discovery controller (CDC) deployment
    Patent number: 12335090
    Abstract: System and method embodiments of centralized discovery controller (CDC) services on a switching network fabric are disclosed. Nodes on the switching network fabric are categorized into leader nodes, e.g., spine switches, and follower nodes, e.g., leaf switches. The CDC services may be divided into centralized CDC services and distributed CDC services, which have direct connections to endpoints for seamless horizontal scaling of endpoints. The centralized CDC services may be placed on a leader node, and the distributed CDC services may be placed among the follower nodes. Operations of the CDC services may be monitored. In case of a node failure, CDC services deployed on the failed node may be moved or transferred to one or more other nodes that have the same role as the failed node. Implementations of the CDC service placement embodiments enable seamless horizontal scaling for endpoints and provide capability for more visibility and monitoring of endpoint.
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: June 17, 2025
    Assignee: DELL PRODUCTS L.P.
    Inventors: Balaji Rajagopalan, Pawan Kumar Singal, Joseph Lasalle White, Charles Park, Ning Zhuang, Sreejith Sethumadhavan, Dhanunjayareddy Madhana
  • Change data capture log augmentation for streamlined ETL processing
    Patent number: 11966411
    Abstract: Techniques for change data capture (CDC) log augmentation are described. In some examples, a user configures CDC log augmentation by indicating which data should be included in a CDC log, and the database, when generating a CDC log associated with this configuration, can obtain the associated data and augment the CDC log by inserting this data into it. The augmented data can include one or more fields from a record in a separate database table, where the record can be identified based on the changed record represented by the CDC log.
    Type: Grant
    Filed: September 12, 2022
    Date of Patent: April 23, 2024
    Assignee: Amazon Technologies, Inc.
    Inventors: Punit Rajgaria, Murali Brahmadesam
  • Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
    Patent number: 11541078
    Abstract: Described herein are compositions and methods related to use of cardiosphere-derived cells and their extracellular vesicles, such as exosomes and microvesicles, for achieving anti-aging and rejuvenation. This includes discoveries for effects on heart structure, function, gene expression, and systemic parameters. For animal studies, intra-cardiac injections of neonatal rat CDCs was compared to in old and young rats including evaluation of blood, echocardiographic, haemodynamic and treadmill stress tests. For in vitro studies, human heart progenitors from older donors, or cardiomyocytes from aged rats were exposed to human CDCs or cardiosphere derived cell (CDC) derived exosomes (CDC-XO) from pediatric donors. CDCs and CDC-XOs were capable of effectuating youthful patterns of gene expression in the hearts of old, along with a variant of physiological and function benefits, including elongation of telomere length.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: January 3, 2023
    Assignee: CEDARS-SINAI MEDICAL CENTER
    Inventors: Eduardo Marban, Lilian Grigorian
  • SYSTEM AND PROCESS FOR SIMULATING THE BEHAVIORAL EFFECTS OF TIMING VIOLATIONS BETWEEN UNRELATED CLOCKS
    Publication number: 20170091361
    Abstract: According to one aspect, embodiments of the invention provide a CDC simulation system comprising a timing analysis module configured to receive a circuit design, analyze the circuit design to identify at least one CDC, and generate a report including information related to the at least one CDC, a CDC simulation module configured to communicate with the timing analysis module and to receive the report from the timing analysis module, and a test bench module configured to communicate with the CDC simulation module, to receive the circuit design, and to operate a test bench code to simulate the operation of the circuit design, wherein the CDC simulation module is further configured to edit a top level of the test bench code, based on the received report, such that the test bench module is configured to identify timing violations in the circuit design due to the at least one CDC.
    Type: Application
    Filed: September 26, 2016
    Publication date: March 30, 2017
    Inventors: Eric Karl Mautner, Wolf Johnson
  • FACILITATING ENDPOINT REGISTRATION USING DISTRIBUTED SERVICES
    Publication number: 20260129103
    Abstract: In a network fabric, such as a network having CLOS topology, non-volatile memory express (NVMe®) endpoints may be connected to one of centralized discovery controller (CDC) distributed services placed among multiple leaf switches, which may have resource constraints. Connection scale, delay, and jitter may occur if the CDC distributed services are not placed on leaf switches close to NVMe endpoints served by the CDC distributed services. System and method embodiments are disclosed for placement of CDC services on a switching network fabric close to endpoints that are served by the CDC services. The placement of CDC services may be implemented via push registration, pull registration, and/or manual DDC adding/registration such that the CDC services may be placed on desired leaf switches close to endpoints.
    Type: Application
    Filed: December 31, 2025
    Publication date: May 7, 2026
    Applicant: DELL PRODUCTS L.P.
    Inventors: Balaji RAJAGOPALAN, Pawan Kumar SINGAL, Ning ZHUANG, Balasubramanian MUTHUKRISHNAN, Baskaran JEYAPAUL, Charles PARK
  • CARDIOSPHERE-DERIVED CELL (CDC) THERAPY FOR THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20230141499
    Abstract: Several embodiments of the methods and compositions disclosed herein relate to methods of treating viral infections, such as those caused by coronaviruses. In some embodiments, CDCs are administered to a patient, to treat the viral infection. In some embodiments, CDC-derived exosomes are administered to a patient. In some embodiments combinations of CDCs and CDC-derived exosomes are used. In still additional embodiments, combination therapies, such as CDCs or CDC-derived exosomes in combination with another therapeutic, such as an anti-inflammotry or other immune modulator are used to treat viral infections. In some embodiments, the viral infection is COVID-19, which is caused by SARS-CoV-2.
    Type: Application
    Filed: March 19, 2021
    Publication date: May 11, 2023
    Inventors: Eduardo Marbán, Linda Marbán
  • CARDIOSPHERE-DERIVED CELLS AND THEIR EXTRACELLULAR VESICLES TO RETARD OR REVERSE AGING AND AGE-RELATED DISORDERS
    Publication number: 20190255119
    Abstract: Described herein are compositions and methods related to use of cardiosphere-derived cells and their extracellular vesicles, such as exosomes and microvesicles, for achieving anti-aging and rejuvenation. This includes discoveries for effects on heart structure, function, gene expression, and systemic parameters. For animal studies, intra-cardiac injections of neonatal rat CDCs was compared to in old and young rats including evaluation of blood, echocardiographic, haemodynamic and treadmill stress tests. For in vitro studies, human heart progenitors from older donors, or cardiomyocytes from aged rats were exposed to human CDCs or cardiosphere derived cell (CDC) derived exosomes (CDC-XO) from pediatric donors. CDCs and CDC-XOs were capable of effectuating youthful patterns of gene expression in the hearts of old, along with a variant of physiological and function benefits, including elongation of telomere length.
    Type: Application
    Filed: September 19, 2017
    Publication date: August 22, 2019
    Applicant: Cedars-Sinai Medical Center
    Inventors: Eduardo Marban, Lilian Grigorian
  • System and process for simulating the behavioral effects of timing violations between unrelated clocks
    Patent number: 10366186
    Abstract: According to one aspect, embodiments of the invention provide a CDC simulation system comprising a timing analysis module configured to receive a circuit design, analyze the circuit design to identify at least one CDC, and generate a report including information related to the at least one CDC, a CDC simulation module configured to communicate with the timing analysis module and to receive the report from the timing analysis module, and a test bench module configured to communicate with the CDC simulation module, to receive the circuit design, and to operate a test bench code to simulate the operation of the circuit design, wherein the CDC simulation module is further configured to edit a top level of the test bench code, based on the received report, such that the test bench module is configured to identify timing violations in the circuit design due to the at least one CDC.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: July 30, 2019
    Assignee: THE CHARLES STARK DRAPER LABORATORY, INC.
    Inventors: Eric Karl Mautner, Wolf Johnson
  • Antisense modulation of CDC-like kinase 1 expression
    Publication number: 20030219895
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of CDC-like kinase 1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CDC-like kinase 1. Methods of using these compounds for modulation of CDC-like kinase 1 expression and for treatment of diseases associated with expression of CDC-like kinase 1 are provided.
    Type: Application
    Filed: May 22, 2002
    Publication date: November 27, 2003
    Applicant: Isis Pharmaceuticals Inc.
    Inventor: Andrew T. Watt
  • Dynamic placement of services closer to endpoint
    Patent number: 12568149
    Abstract: In a network fabric, such as a network having CLOS topology, non-volatile memory express (NVMe®) endpoints may be connected to one of centralized discovery controller (CDC) distributed services placed among multiple leaf switches, which may have resource constraints. Connection scale, delay, and jitter may occur if the CDC distributed services are not placed on leaf switches close to NVMe endpoints served by the CDC distributed services. System and method embodiments are disclosed for placement of CDC services on a switching network fabric close to endpoints that are served by the CDC services. The CDC services may be placed on desired leaf switches close to endpoints.
    Type: Grant
    Filed: July 21, 2022
    Date of Patent: March 3, 2026
    Assignee: DELL PRODUCTS L.P.
    Inventors: Balaji Rajagopalan, Pawan Kumar Singal, Ning Zhuang, Balasubramanian Muthukrishnan, Baskaran Jeyapaul, Charles Park
  • DYNAMIC PLACEMENT OF SERVICES CLOSER TO ENDPOINT
    Publication number: 20240031446
    Abstract: In a network fabric, such as a network having CLOS topology, non-volatile memory express (NVMe®) endpoints may be connected to one of centralized discovery controller (CDC) distributed services placed among multiple leaf switches, which may have resource constraints. Connection scale, delay, and jitter may occur if the CDC distributed services are not placed on leaf switches close to NVMe endpoints served by the CDC distributed services. System and method embodiments are disclosed for placement of CDC services on a switching network fabric close to endpoints that are served by the CDC services. The placement of CDC services may be implemented via push registration, pull registration, and/or manual DDC adding/registration such that the CDC services may be placed on desired leaf switches close to endpoints.
    Type: Application
    Filed: July 21, 2022
    Publication date: January 25, 2024
    Applicant: DELL PRODUCTS L.P.
    Inventors: Balaji RAJAGOPALAN, Pawan Kumar SINGAL, Ning ZHUANG, Balasubramanian MUTHUKRISHNAN, Baskaran JEYAPAUL, Charles PARK
  • Antisense modulation of CDC14A expression
    Publication number: 20040077571
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of CDC14A. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CDC14A. Methods of using these compounds for modulation of CDC14A expression and for treatment of diseases associated with expression of CDC14A are provided.
    Type: Application
    Filed: October 17, 2002
    Publication date: April 22, 2004
    Applicants: Isis Pharmaceuticals Inc., Abbott Laboratories
    Inventors: Susan M. Freier, Aparna Sarthy, Thomas McGonigal
  • Antisense modulation of CDC14A expression
    Publication number: 20040077085
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of CDC14A. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CDC14A. Methods of using these compounds for modulation of CDC14A expression and for treatment of diseases associated with expression of CDC14A are provided.
    Type: Application
    Filed: October 17, 2002
    Publication date: April 22, 2004
    Applicant: Isis Pharmaceuticals Inc.
    Inventor: Susan M. Freier
  • COMPUTER SYSTEM AND COMMUNICATION METHOD
    Publication number: 20230370332
    Abstract: A GC cluster is a computer system in which a cluster of nodes on which a containerized application runs is constructed. The GC cluster communicates with a first CDC cluster that is another computer system in which the cluster is constructed and to which data on the containerized application is transmitted. The GC cluster communicates with a second CDC cluster that is still another computer system in which the cluster is constructed and to which the data is transmitted instead of the first CDC cluster. The GC cluster receives a bfd packet repeatedly transmitted from the first CDC cluster. The GC cluster transmits the data to the second CDC cluster instead of the first CDC cluster when the bfd packet transmitted from the first CDC cluster has not been received.
    Type: Application
    Filed: January 22, 2021
    Publication date: November 16, 2023
    Applicant: RAKUTEN MOBILE, INC.
    Inventor: Kazushige TAKEUCHI
  • Human rotavirus strains and vaccines
    Patent number: 11786589
    Abstract: A vaccine composition and method of vaccination are provided useful for immunizing a subject against a rotavirus. The vaccines include rotavirus strains CDC-9 and CDC-66, fragments thereof, homologues thereof, or combinations thereof. Inventive vaccines may include a fragment of CDC-9, CDC-66, homologues thereof, or combinations thereof. Methods of inducing an immunological response are provided by administering an inventive vaccine.
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: October 17, 2023
    Assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services
    Inventors: Baoming Jiang, Roger I. Glass, Yuhuan Wang, Jon Gentsch
  • CARDIOSPHERE-DERIVED CELLS AND THEIR EXTRACELLULAR VESICLES FOR TREATMENT AND PREVENTION OF CANCER
    Publication number: 20210085724
    Abstract: Described herein are methods and compositions related to treating cancer using cardiosphere derived cells (CDCs) and/or extracellular vesicles (EVs). In some embodiments, the EVs are heart-derived EVs (e.g., cardiosphere-derived exosomes, CDC-derived exosomes, cardiosphere-derived microvesicles, CDC-derived microvesicles, or combinations thereof). In some embodiments, methods of treating cancer in a subject are provided. In some embodiments, CDCs and/or EVs are administered to a subject to treat cancer. In some embodiments, the CDCs and/or EVs are provided in a pharmaceutical formulation.
    Type: Application
    Filed: August 2, 2018
    Publication date: March 25, 2021
    Inventors: Eduardo MARBAN, Lilian GRIGORIAN
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