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  • Publication number: 20090270594
    Abstract: The invention concerns the use of thymosin alpha 1 for the preparation of a medicament for the prevention and treatment of allergies
    Type: Application
    Filed: September 27, 2007
    Publication date: October 29, 2009
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE
    Inventors: Luigina Romani, Francesco Bistoni, Enrico Garaci, Guido Rasi, Paola Sinibaldi Vallebona
  • Patent number: 9150627
    Abstract: The invention relates to novel, Frizzled-like, immunogenic peptides, useful for the stimulation of an immune response against various cancer types, particularly colon rectal carcinoma.
    Type: Grant
    Filed: December 29, 2005
    Date of Patent: October 6, 2015
    Inventors: Vito M. Fazio, Enrico Garaci, Guido Rasi, Monica Rinaldi, Paola Sinibaldi
  • Publication number: 20100004174
    Abstract: The invention concerns the use of thymosin alpha 1 for the preparation of a medicament for the prevention and treatment of autoimmune diseases such as multiple sclerosis, and inflammatory bowel diseases such as Crohn's disease or ulcerative colitis.
    Type: Application
    Filed: September 27, 2007
    Publication date: January 7, 2010
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE
    Inventors: Luigina Romani, Francesco Bistoni, Enrico Garaci, Guido Rasi, Paola Sinbaldi Vallebona
  • Publication number: 20120295840
    Abstract: A method for treating a human infected with Aspergillus by using thymosin alpha 1 as an immuno-stimulator in activating dendritic cells. The method is particularly useful in preventing an infection by Aspergillus in an immuno-compromised host being treated with a bone marrow transplantation.
    Type: Application
    Filed: May 29, 2012
    Publication date: November 22, 2012
    Applicant: SCICLONE PHARMACEUTICALS, INC.
    Inventors: Guido RASI, Enrico GARACI, Francesco BISTONI, Luigina ROMANI, Paolo Di Francesco
  • Publication number: 20090232837
    Abstract: The invention relates to novel, Frizzled-like, immunogenic peptides, useful for the stimulation of an immune response against various cancer types, particularly colon rectal carcinoma.
    Type: Application
    Filed: December 29, 2005
    Publication date: September 17, 2009
    Inventors: Vito M. Fazio, Enrico Garaci, Guido Rasi, Monica Rinaldi, Paola Sinibaldi
  • Publication number: 20070129292
    Abstract: A method for treating a human infected with Aspergillus by using thymosin alpha 1 as an immuno-stimulator in activating dendritic cells. The method is particularly useful in preventing an infection by Aspergillus in an immuno-compromised host being treated with a bone marrow transplantation.
    Type: Application
    Filed: March 29, 2004
    Publication date: June 7, 2007
    Applicant: SciClone Pharmaceuticals, Inc.
    Inventors: Guido Rasi, Enrico Garaci, Francesco Bistoni, Luigina Romani, Paolo Di Francesco
  • Patent number: 8207294
    Abstract: A method for treating a human infected with Aspergillus by using thymosin alpha 1 as an immuno-stimulator in activating dendritic cells. The method is particularly useful in preventing an infection by Aspergillus in an immuno-compromised host being treated with a bone marrow transplantation.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: June 26, 2012
    Assignee: SciClone Pharmaceuticals, Inc.
    Inventors: Guido Rasi, Enrico Garaci, Francesco Bistoni, Luigina Romani, Paolo Di Francesco
  • Patent number: 8389680
    Abstract: A method for treating a human infected with Aspergillus by using thymosin alpha 1 as an immuno-stimulator in activating dendritic cells. The method is particularly useful in preventing an infection by Aspergillus in an immuno-compromised host being treated with a bone marrow transplantation.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: March 5, 2013
    Assignee: SciClone Pharmaceuticals, Inc.
    Inventors: Guido Rasi, Enrico Garaci, Francesco Bistoni, Luigina Romani, Paolo Di Francesco
  • Publication number: 20060052297
    Abstract: The present invention provides a method for up-regulating tumor cell antigen expression, comprising administering to the cells an amount of thymalfasin sufficient to increase the expression of TLP relative to that of untreated tumor cells. Also provided are methods for enhancing the sensitivity of a immunodiagnostic or immunotherapeutic method, comprising pre-treating target tumor cells by administering to the cells an amount of thymalfasin sufficient to increase the expression of TLP relative to that of untreated tumor cells, followed by application of the immunodiagnostic or immunotherapeutic method. These methods are applicable to both in vivo and in vitro diagnostic methods, and to in vivo immunotherapeutic methods.
    Type: Application
    Filed: June 30, 2003
    Publication date: March 9, 2006
    Inventors: Guido Rasi, Enrico Garaci, Paolo Sinibaldi-Vallebona
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