Search Patents
  • METHIONINE AND CYSTEINE DEPRIVATION DIET AND FORMULATIONS TO INCREASE EFFECTIVENESS OF CANCER THERAPY
    Publication number: 20220211752
    Abstract: Ferroptosis (cell death mediated by iron-dependent lipid peroxide accumulation) results from lipid peroxidation of phospholipids containing polyunsaturated fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid peroxidation via the activity of the enzyme glutathione peroxidase 4 (GPX-4), is generated directly from the sulfur-containing aminoacid cysteine, and indirectly from methionine via the transsulfuration pathway. Cysteine and methionine deprivation (CMD) in the diet can synergistically increase RSL3-mediated cell death and lipid peroxidation in both murine and human glioma cell lines and in ex-vivo organotypic slice cultures. A cysteine-depleted, methionine-restricted diet can improve survival in an syngeneic orthotopic murine glioma model. This CMD diet leads to profound in-vivo metabolomic, proteomic and lipidomic alterations, leading to improvements in the efficacy of ferroptotic therapies in glioma treatment with a non-invasive dietary modification.
    Type: Application
    Filed: November 26, 2021
    Publication date: July 7, 2022
    Inventors: Pavan Upadhyayula, Dominique Higgins, Jeffrey N. Bruce, Simon Cheng, Kunal Chaudhary, Peter Canoll, Brent Stockwell, Athanassios Dovas
  • Method of forming a cylindrical container stacked capacitor
    Patent number: 5604147
    Abstract: A semiconductor processing method of forming a stacked container capacitor includes, a) providing a pair of spaced conductive runners relative to a substrate, the conductive runners respectively having electrically insulative sidewall spacers and an electrically insulative cap, the caps having respective outer surfaces; b) providing a node between the runners to which electrical connection to a capacitor is to be made; c) providing an electrically conductive pillar in electrical connection with the node, the pillar projecting outwardly relative to the node between the runners and having a first outer surface positioned outwardly of both runner caps, the pillar completely filling the space between the pair of runners at the location where the pillar is located; d) providing an insulating dielectric layer outwardly of the caps and the conductive pillar; e) etching a container opening through the insulating dielectric layer to outwardly expose the conductive pillar first outer surface; f) etching the exposed con
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: February 18, 1997
    Assignee: Micron Technology, Inc.
    Inventors: Mark Fischer, Mark Jost, Kunal Parekh
  • Method of forming a bit line over capacitor array of memory cells and an array of bit line over capacitor array of memory cells
    Patent number: 5563089
    Abstract: A semiconductor memory device includes, a) a semiconductor substrate; b) a field effect transistor gate positioned outwardly of the semiconductor substrate; c) opposing active areas formed within the semiconductor substrate on opposing sides of the gate; d) a capacitor electrically connected with one of the active areas; e) a bit line; f) a dielectric insulating layer positioned intermediate the bit line and the active areas; g) a bit line plug extending through the insulating layer and electrically interconnecting the bit line with the other active area, the bit line plug comprising an electrically conductive annular ring. Integrated circuitry, beyond memory devices, utilizing an annular interconnection ring are also disclosed. Such constructions having additional radially inward insulating annular rings and conductive rings are also disclosed. A method of forming a bit line over capacitor array of memory cells having such rings is also disclosed.
    Type: Grant
    Filed: February 22, 1995
    Date of Patent: October 8, 1996
    Assignee: Micron Technology, Inc.
    Inventors: Mark Jost, Charles H. Dennison, Kunal Parekh
  • Methods of forming recessed access devices associated with semiconductor constructions
    Patent number: 7897460
    Abstract: The invention includes methods of forming recessed access devices. A substrate is provided to have recessed access device trenches therein. A pair of the recessed access device trenches are adjacent one another. Electrically conductive material is formed within the recessed access device trenches, and source/drain regions are formed proximate the electrically conductive material. The electrically conductive material and source/drain regions together are incorporated into a pair of adjacent recessed access devices. After the recessed access device trenches are formed within the substrate, an isolation region trench is formed between the adjacent recessed access devices and filled with electrically insulative material to form a trenched isolation region.
    Type: Grant
    Filed: March 19, 2008
    Date of Patent: March 1, 2011
    Assignee: Micron Technology, Inc.
    Inventors: Kunal R. Parekh, Suraj Mathew, Jigish D. Trivedi, John K. Zahurak, Sanh D. Tang
  • Methods of forming recessed access devices associated with semiconductor constructions
    Patent number: 8067286
    Abstract: The invention includes methods of forming recessed access devices. A substrate is provided to have recessed access device trenches therein. A pair of the recessed access device trenches are adjacent one another. Electrically conductive material is formed within the recessed access device trenches, and source/drain regions are formed proximate the electrically conductive material. The electrically conductive material and source/drain regions together are incorporated into a pair of adjacent recessed access devices. After the recessed access device trenches are formed within the substrate, an isolation region trench is formed between the adjacent recessed access devices and filled with electrically insulative material to form a trenched isolation region.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: November 29, 2011
    Assignee: Micron Technology, Inc.
    Inventors: Kunal R. Parekh, Suraj J. Mathew, Jigish D. Trivedi, John K. Zahurak, Sanh D. Tang
  • SENSOR ASSEMBLY
    Publication number: 20230124645
    Abstract: A sensor assembly includes a housing defining a chamber. A sensor unit is supported by the housing and extends vertically upward along an axis from the housing. The sensor unit includes a base and a sensor housing mounted to the base and rotatable relative to the base about the axis. The sensor unit includes a sensor. The sensor housing extends circumferentially around the sensor and defines a sensor chamber therebetween. A blower box is supported by the housing in the chamber. The blower box defines a blower chamber in fluid communication with the sensor chamber. A blower is disposed in the blower box.
    Type: Application
    Filed: October 20, 2021
    Publication date: April 20, 2023
    Applicant: Ford Global Technologies, LLC
    Inventors: Michael Robertson, JR., Venkatesh Krishnan, Rashaun Phinisee, Kunal Chaudhari
  • Vehicle sensor assembly
    Patent number: 12155916
    Abstract: A vehicle includes a window; a sensor housing including an air inlet, a first air outlet, and a second air outlet; an image sensor supported by the sensor housing; and a blower positioned to draw in air through the air inlet and expel the air through the first air outlet and the second air outlet. The first air outlet is aimed at the image sensor, and the second air outlet is aimed at the window.
    Type: Grant
    Filed: May 17, 2022
    Date of Patent: November 26, 2024
    Assignee: Ford Global Technologies, LLC
    Inventors: Anthony Michael Regalbuto, Venkatesh Krishnan, Kunal Chaudhari, Michael Robertson, Jr.
  • SENSOR ASSEMBLY WITH CLEANING
    Publication number: 20240198975
    Abstract: A sensor assembly includes a sensor including a sensor window, a cover fixed relative to the sensor, a bracket supporting the sensor, a duct extending around the sensor from an inlet at the cover adjacent to the sensor to an outlet at the cover adjacent to the sensor on an opposite side of the sensor from the inlet, and a deflector fixed relative to the sensor and spaced downwardly from the sensor. The cover is positioned to expose at least a portion of the sensor window. The duct extends between the sensor and the bracket. The deflector is shaped to direct airflow toward the sensor.
    Type: Application
    Filed: December 15, 2022
    Publication date: June 20, 2024
    Applicant: Ford Global Technologies, LLC
    Inventors: Kunal Chaudhari, Tyler D. Hamilton, Venkatesh Krishnan, Subba Reddy Boggu
  • SENSOR ASSEMBLY AND METHOD OF INSTALLING TO A VEHICLE
    Publication number: 20230406219
    Abstract: An assembly for mounting a sensor to a vehicle includes a base, a sensor bracket, and a tolerance compensator between the base and the sensor bracket. The tolerance compensator is threadedly coupled to the base and releasably engaged with the sensor bracket in an assembled position. The assembly includes a washer including a hub fixed relative to the base and a plurality of tabs arranged circumferentially around the hub and extending radially relative to the hub. One of the tabs is moveable into engagement with the tolerance compensator in the assembled position.
    Type: Application
    Filed: May 25, 2022
    Publication date: December 21, 2023
    Applicant: Ford Global Technologies, LLC
    Inventors: Michael Robertson,, JR., Tyler D. Hamilton, Kunal Chaudhari, Venkatesh Krishnan
  • Sensor assembly with cleaning
    Patent number: 12351138
    Abstract: A sensor assembly includes a sensor including a sensor window, a cover fixed relative to the sensor, a bracket supporting the sensor, a duct extending around the sensor from an inlet at the cover adjacent to the sensor to an outlet at the cover adjacent to the sensor on an opposite side of the sensor from the inlet, and a deflector fixed relative to the sensor and spaced downwardly from the sensor. The cover is positioned to expose at least a portion of the sensor window. The duct extends between the sensor and the bracket. The deflector is shaped to direct airflow toward the sensor.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: July 8, 2025
    Assignee: Ford Global Technologies, LLC
    Inventors: Kunal Chaudhari, Tyler D. Hamilton, Venkatesh Krishnan, Subba Reddy Boggu
  • VEHICLE SENSOR ASSEMBLY
    Publication number: 20230379560
    Abstract: A vehicle includes a window; a sensor housing including an air inlet, a first air outlet, and a second air outlet; an image sensor supported by the sensor housing; and a blower positioned to draw in air through the air inlet and expel the air through the first air outlet and the second air outlet. The first air outlet is aimed at the image sensor, and the second air outlet is aimed at the window.
    Type: Application
    Filed: May 17, 2022
    Publication date: November 23, 2023
    Applicant: Ford Global Technologies, LLC
    Inventors: Anthony Michael Regalbuto, Venkatesh Krishnan, Kunal Chaudhari, Michael Robertson, JR.
  • Sensor assembly and method of installing to a vehicle
    Patent number: 12377790
    Abstract: An assembly for mounting a sensor to a vehicle includes a base, a sensor bracket, and a tolerance compensator between the base and the sensor bracket. The tolerance compensator is threadedly coupled to the base and releasably engaged with the sensor bracket in an assembled position. The assembly includes a washer including a hub fixed relative to the base and a plurality of tabs arranged circumferentially around the hub and extending radially relative to the hub. One of the tabs is moveable into engagement with the tolerance compensator in the assembled position.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: August 5, 2025
    Assignee: Ford Global Technologies, LLC
    Inventors: Michael Robertson, Jr., Tyler D. Hamilton, Kunal Chaudhari, Venkatesh Krishnan
  • SENSOR ASSEMBLY WITH CLEANING
    Publication number: 20230135748
    Abstract: A sensor assembly includes a sensor including a sensor lens, the sensor lens defining an axis; a housing panel including an aperture centered on the axis, the sensor lens being recessed from the aperture along the axis; and an air nozzle positioned between the aperture and the sensor lens along the axis and oriented to blow horizontally across the sensor lens. The aperture and the sensor lens define a gap positioned on an opposite lateral side of the sensor lens from the air nozzle.
    Type: Application
    Filed: November 3, 2021
    Publication date: May 4, 2023
    Applicant: Ford Global Technologies, LLC
    Inventors: Michael Robertson, JR., Rashaun Phinisee, Venkatesh Krishnan, Anthony Michael Regalbuto, Kunal Chaudhari
  • Sensor assembly with cleaning
    Patent number: 12030463
    Abstract: A sensor assembly includes a sensor including a sensor lens, the sensor lens defining an axis; a housing panel including an aperture centered on the axis, the sensor lens being recessed from the aperture along the axis; and an air nozzle positioned between the aperture and the sensor lens along the axis and oriented to blow horizontally across the sensor lens. The aperture and the sensor lens define a gap positioned on an opposite lateral side of the sensor lens from the air nozzle.
    Type: Grant
    Filed: November 3, 2021
    Date of Patent: July 9, 2024
    Assignee: Ford Global Technologies, LLC
    Inventors: Michael Robertson, Jr., Rashaun Phinisee, Venkatesh Krishnan, Anthony Michael Regalbuto, Kunal Chaudhari
  • Sensor assembly with cleaning
    Patent number: 12115948
    Abstract: A sensor assembly includes a sensor including a cylindrical sensor window defining an axis, a cover fixed relative to the sensor, and a duct mounted to the sensor and extending through the axis. The cover is positioned to expose a circumferential portion of the sensor window. The circumferential portion extends circumferentially relative to the axis from a first end adjacent to the cover to a second end adjacent to the cover. The circumferential portion includes a midpoint circumferentially between the first end and the second end. The duct includes an inlet and an outlet. The outlet extends circumferentially from the first end of the circumferential portion to the second end of the circumferential portion. The duct includes a deflector positioned to direct airflow from the inlet to the outlet at the first end and second end of the circumferential portion before the airflow reaches the midpoint of the circumferential portion.
    Type: Grant
    Filed: October 20, 2021
    Date of Patent: October 15, 2024
    Assignee: Ford Global Technologies, LLC
    Inventors: Tyler D. Hamilton, Kunal Chaudhari, Venkatesh Krishnan, Anthony Michael Regalbuto, Subba Reddy Boggu
  • SENSOR ASSEMBLY WITH CLEANING
    Publication number: 20230120545
    Abstract: A sensor assembly includes a sensor including a cylindrical sensor window defining an axis, a cover fixed relative to the sensor, and a duct mounted to the sensor and extending through the axis. The cover is positioned to expose a circumferential portion of the sensor window. The circumferential portion extends circumferentially relative to the axis from a first end adjacent to the cover to a second end adjacent to the cover. The circumferential portion includes a midpoint circumferentially between the first end and the second end. The duct includes an inlet and an outlet. The outlet extends circumferentially from the first end of the circumferential portion to the second end of the circumferential portion. The duct includes a deflector positioned to direct airflow from the inlet to the outlet at the first end and second end of the circumferential portion before the airflow reaches the midpoint of the circumferential portion.
    Type: Application
    Filed: October 20, 2021
    Publication date: April 20, 2023
    Applicant: Ford Global Technologies, LLC
    Inventors: Tyler D. Hamilton, Kunal Chaudhari, Venkatesh Krishnan, Anthony Michael Regalbuto, Subba Reddy Boggu
  • SENSOR ASSEMBLY WITH BAFFLES
    Publication number: 20240416871
    Abstract: A sensor assembly includes a sensor having a lens defining an axis. An air nozzle is aimed to direct air across the lens and defines a direction of airflow along a longitudinal axis of the air nozzle. The longitudinal axis is transverse to the axis. A plurality of baffles are disposed in the air nozzle and spaced from each other. The baffles extend partially across the air nozzle relative to the axis.
    Type: Application
    Filed: June 14, 2023
    Publication date: December 19, 2024
    Applicant: Ford Global Technologies, LLC
    Inventors: Kunal Chaudhari, Michael Robertson, JR., Rashaun Phinisee, Venkatesh Krishnan, Anthony Michael Regalbuto, Mallikarjun Sukumar
  • SENSOR ASSEMBLY FOR A VEHICLE
    Publication number: 20230135961
    Abstract: A sensor assembly includes a first sensing device and a second sensing device spaced from the first sensing device. The sensor assembly includes a bracket supporting the first sensing device and the second sensing device and a sensor cover including a first sensor window and a second sensor window. The first sensing device has a first field of view through the first sensor window and the second sensing device having a second field of view through the second sensor window. The sensor assembly includes an air nozzle housing supported by the bracket and defining a first air nozzle aimed toward the first sensor window and a second air nozzle aimed toward the second sensor window. The sensor assembly includes a washer nozzle spaced from the first air nozzle. The washer nozzle aimed toward the first sensor window in a direction opposite to a direction of the first air nozzle.
    Type: Application
    Filed: November 3, 2021
    Publication date: May 4, 2023
    Applicant: Ford Global Technologies, LLC
    Inventors: Tyler D. Hamilton, Kunal Chaudhari, Venkatesh Krishnan, Camila Silva, Michael Robertson, Jr., Anthony Michael Regalbuto
  • Sensor assembly for a vehicle
    Patent number: 11827189
    Abstract: A sensor assembly includes a first sensing device and a second sensing device spaced from the first sensing device. The sensor assembly includes a bracket supporting the first sensing device and the second sensing device and a sensor cover including a first sensor window and a second sensor window. The first sensing device has a first field of view through the first sensor window and the second sensing device having a second field of view through the second sensor window. The sensor assembly includes an air nozzle housing supported by the bracket and defining a first air nozzle aimed toward the first sensor window and a second air nozzle aimed toward the second sensor window. The sensor assembly includes a washer nozzle spaced from the first air nozzle. The washer nozzle aimed toward the first sensor window in a direction opposite to a direction of the first air nozzle.
    Type: Grant
    Filed: November 3, 2021
    Date of Patent: November 28, 2023
    Assignee: Ford Global Technologies, LLC
    Inventors: Tyler D. Hamilton, Kunal Chaudhari, Venkatesh Krishnan, Camila Silva, Michael Robertson, Jr., Anthony Michael Regalbuto
  • SENSOR ASSEMBLY WITH VELOCITY STACK
    Publication number: 20230101656
    Abstract: A sensor assembly includes a housing defining a chamber. A sensor is disposed in the chamber and has a lens. An air nozzle is aimed to direct air across the lens. A blower is disposed in the chamber and in fluid communication with the air nozzle. A velocity stack is mounted to the blower and includes an air foil and an outer wall spaced from the air foil and extending entirely around the air foil. The air foil and the outer wall define a channel therebetween. The blower is in fluid communication with the chamber through the channel.
    Type: Application
    Filed: September 29, 2021
    Publication date: March 30, 2023
    Applicant: Ford Global Technologies, LLC
    Inventors: Michael Robertson, Jr., Tyler D. Hamilton, Anthony Michael Regalbuto, Rashaun Phinisee, Kunal Chaudhari, Venkatesh Krishnan
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