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  • MULTILAYERED MAGNETIC MICELLE COMPOSITIONS AND METHODS FOR THEIR USE
    Publication number: 20150064116
    Abstract: Provided herein are compositions comprising a micelle having a hydrophobic superparmagnetic iron oxide nanoparticle (SPION) core, a first coating comprising a cationic polymer, and a second coating comprising a polynucleotide. Also provided are methods of using the compositions for transfection and/or transformation of a cell with the polynucleotide. Further provided are methods of detecting transfection of a cell with the polynucleotide.
    Type: Application
    Filed: September 28, 2012
    Publication date: March 5, 2015
    Applicant: University of South Florida (A Florida Non-Profit Corporation)
    Inventors: Subhra Mohapatra, Chunyan Wang
  • Multilayered magnetic micelle compositions and methods for their use
    Patent number: 9439978
    Abstract: Provided herein are compositions comprising a micelle having a hydrophobic superparmagnetic iron oxide nanoparticle (SPION) core, a first coating comprising a cationic polymer, and a second coating comprising a polynucleotide. Also provided are methods of using the compositions for transfection and/or transformation of a cell with the polynucleotide. Further provided are methods of detecting transfection of a cell with the polynucleotide.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: September 13, 2016
    Assignees: University of South Florida, The United States of America as represented by National Institutes of Health (NIH), U.S. Dept. of Health and Human Services (DHHS), U.S. Government
    Inventors: Subhra Mohapatra, Chunyan Wang
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