Abstract: Provided herein are compositions comprising a micelle having a hydrophobic superparmagnetic iron oxide nanoparticle (SPION) core, a first coating comprising a cationic polymer, and a second coating comprising a polynucleotide. Also provided are methods of using the compositions for transfection and/or transformation of a cell with the polynucleotide. Further provided are methods of detecting transfection of a cell with the polynucleotide.
Type:
Grant
Filed:
September 28, 2012
Date of Patent:
September 13, 2016
Assignees:
University of South Florida, The United States of America as represented by National Institutes of Health (NIH), U.S. Dept. of Health and Human Services (DHHS), U.S. Government
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