Search Patents
  • Publication number: 20140346052
    Abstract: Provided are a reaction vessel for Raman spectrophotometry and a Raman spectrophotometry method using the same, which are suitable for observing an electrochemical reaction at a solid surface in an electrolyte solution. The reaction vessel for Raman spectrophotometry includes: a housing portion including a transparent window portion, in which a hollow portion for storing an electrolyte solution is formed; and a working electrode portion configured from a conductive material that is electrochemically inactive in the electrolyte solution, the working electrode portion including one part arranged facing the window portion in the hollow portion to hold a sample, and another part extended to outside the housing portion to be connected to an external power source.
    Type: Application
    Filed: November 1, 2012
    Publication date: November 27, 2014
    Inventors: Jun-ichi Ozaki, Naokatsu Kannari, Yuta Horikawa, Rieko Kobayashi, Naoto Saito
  • Publication number: 20020101586
    Abstract: A spectrophotometer and spectrophotometry, using a precision drive means at the photodiode array, is disclosed. The drive means precisely moves the photodiode array by a distance equal to the physical interval between the photodiodes of the photodiode array. Therefore, the spectrophotometer and spectrophotometry of this invention primarily measures light intensities of incident light by the photodiode array, and precisely moves the photodiode array using the drive means by the distance equal to the physical interval between photodiodes of the photodiode array, and measures the light intensities of the incident light at desired positions corresponding to the intervals.
    Type: Application
    Filed: April 11, 2001
    Publication date: August 1, 2002
    Inventors: Soo Hyun Kim, Kyung Chan Kim, Se Baek Oh
  • Publication number: 20100198029
    Abstract: Non-invasive spectrophotometric monitoring of oxygen saturation levels based on a combination of continuous wave spectrophotometry (CWS) and phase modulation spectrophotometry (PMS) is described. First information representative of absolute oxygen saturation levels in relatively shallow regions of a patient tissue volume are acquired from PMS-based monitoring thereof during a reference interval. Second information representative of non-absolute oxygen saturation levels in relatively deep regions of the tissue volume are acquired from CWS-based monitoring thereof during the reference interval. Based on the first and second information acquired during the reference interval, a mapping is automatically determined between the second information and estimated absolute oxygen saturation metrics for the relatively deep regions.
    Type: Application
    Filed: February 5, 2010
    Publication date: August 5, 2010
    Applicant: O2 MEDTECH, INC.
    Inventor: Shih-Ping WANG
  • Patent number: 6494576
    Abstract: A method and apparatus for spectrophotometry for non-invasively measuring the chemistry of the blood in the eye.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: December 17, 2002
    Inventor: Francis A. L'Esperance, Jr.
  • Patent number: 5280177
    Abstract: A sample cell for infrared spectrophotometry comprises a sample holder for holding a sample to be analyzed by infrared spectrophotometry, a cool air passageway and a vortex tube. The sample holder includes a primary optical surface through which infrared radiation is directed to a sample contained in the holder, and the cool air passageway is adjacent the primary optical surface of the sample holder for directing a cool air stream across the primary optical surface. The vortex tube has a cool air outlet connected to the cool air passageway for supplying cool air to the passageway.
    Type: Grant
    Filed: October 15, 1992
    Date of Patent: January 18, 1994
    Assignee: The United States of America as represented by the Secretary of Commerce
    Inventor: Thomas J. Bruno
  • Patent number: 6727988
    Abstract: A spectrophotometer and spectrophotometry method, using a precision drive at a photodiode array which precisely moves the photodiode array by a distance equal to the physical interval between the photodiodes of the photodiode array so that the spectrophotometer and spectrophotometry method primarily measures light intensities of incident light by the photodiode array, and when precisely moves the photodiode array using the drive by the distance equal to the physical interval between photodiodes of the photodiode array, measures the light intensities of the incident light at desired positions corresponding to the intervals.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: April 27, 2004
    Assignee: Korea Advanced Institute of Science and Technology
    Inventors: Soo Hyun Kim, Kyung Chan Kim, Se Baek Oh
  • Publication number: 20210231560
    Abstract: The present disclosure relates to using spectrophotometry to estimate genome copies and full/empty ratios adeno-associated virus particles.
    Type: Application
    Filed: April 27, 2019
    Publication date: July 29, 2021
    Inventors: Zhuchun WU, Keith WEBBER, Brian HOWIE, Li ZHI
  • Patent number: 4283141
    Abstract: A displaceable combination of a sample solution cell and a one-piece plastic stirrer is provided for spectrophotometry. The cell has an opening at one end through which the stirrer is inserted and arranged for reciprocation in the cell by engagement of a portion outside the cell. The stirrer is also arranged to sit in the cell during passage of radiation therethrough upon spectrophotographic measurement of the sample.
    Type: Grant
    Filed: February 5, 1979
    Date of Patent: August 11, 1981
    Assignee: Pye (Electronic Products) Limited
    Inventors: Trevor J. Stockdale, Anthony R. L. Moss
  • Publication number: 20170333895
    Abstract: Disclosed herein are multiwell plates suitable for spectrophotometry for low-volume liquid samples. For the multiwell plates, the bottom of at least one well has a layer of porous matrix disposed thereon, or is comprised of a layer of porous matrix. The layer of porous matrix permits a low-volume liquid sample to distribute evenly across the porous matrix. Also disclosed herein are methods of performing a photometric or spectrophotometric measurement on a liquid sample having a small volume, by using a multiwell plate comprising a layer of porous matrix.
    Type: Application
    Filed: October 22, 2015
    Publication date: November 23, 2017
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: James J. Collins, Keith Pardee
  • Publication number: 20030111194
    Abstract: A system and method for rapidly determining the pulp kappa number through direct measurement of the potassium permanganate concentration in a pulp-permanganate solution using spectrophotometry. Specifically, the present invention uses strong acidification to carry out the pulp-permanganate oxidation reaction in the pulp-permanganate solution to prevent the precipitation of manganese dioxide (MnO2). Consequently, spectral interference from the precipitated MnO2 is eliminated and the oxidation reaction becomes dominant. The spectral intensity of the oxidation reaction is then analyzed to determine the pulp kappa number.
    Type: Application
    Filed: September 3, 2002
    Publication date: June 19, 2003
    Applicant: Institute of Paper Science and Technology, Inc.
    Inventors: Xin-Sheng Chai, Jun Yong Zhu
  • Publication number: 20110292387
    Abstract: A simple method and apparatus for circular dichroism spectrophotometry are provided that allow a liquid, cream-type, and gel-type specimens having a low degree of transparency to be measured directly and nondestructively without passing light through the specimens. Right-handed or left-handed circularly polarized light enters a prism from an entrance face and hits a specimen mounting face of the prism, on which a specimen is placed, at an angle of 80°. Then, after being totally reflected by the specimen mounting face and going out from an exit face, the light is detected, and the absorbance is determined.
    Type: Application
    Filed: May 24, 2011
    Publication date: December 1, 2011
    Applicant: JASCO CORPORATION
    Inventors: Yoshiro Kondo, Ettore Castiglioni
  • Publication number: 20020140940
    Abstract: A system and method for measurement and analysis of a sample by absorption spectrophotometry is taught by the present invention. According to various embodiments, the invention utilizes a novel receptacle comprising of at plurality of layers including a transparent layer, a channel layer, and a reflective layer coupled to one another and allowing for fluid communication within and among the layers to allow for illumination by a light source and interrogation and analysis by a light measuring device. Examples of the light source and light measuring devices that could be used with the present invention include reflectance and/or fluorescence spectroscopy and a spectrometer, respectively. Measurement and analysis of a sample is compared to known values of constituents for comparison.
    Type: Application
    Filed: February 27, 2002
    Publication date: October 3, 2002
    Inventors: Shabbir B. Bambot, Scott Kerr, Mark A. Samuels, Henry Grage, Gregory J. Newman
  • Publication number: 20080071154
    Abstract: Embodiments of the present invention relate to a system and method for practicing spectrophotometry using light emitting nanostructures. Specifically, embodiments of the present invention include a physiologic sensor comprising a sensor body configured for placement adjacent pulsatile tissue of a patient, a first light emitting nanostructure device configured to emit light at a first wavelength through the pulsatile tissue, a second light emitting nanostructure device configured to emit light at a second wavelength through the pulsatile tissue, and a light detector configured to detect the light at the first wavelength and the light at the second wavelength after dispersion through the pulsatile tissue.
    Type: Application
    Filed: September 20, 2006
    Publication date: March 20, 2008
    Inventors: Gilbert Hausmann, Michael P. O'Neil, Paul Mannheimer
  • Patent number: 5450194
    Abstract: An optical measuring device, particularly using spectrophotometry, which comprises at least one group of optical fibers (24) connected to measuring cells, at least one auxiliary optical fiber (30) and at least one selection member connecting the latter to the group. The selective member establishes a link between the auxiliary fiber and one of the fibers of the group. The selection member comprises fixed optical means (32, 34 ) for establishing the link between the group and the auxiliary fiber and retractable seals (36) associated with the fibers of the group and which seal the ends of auxiliary fibers leading to said member.
    Type: Grant
    Filed: March 17, 1994
    Date of Patent: September 12, 1995
    Inventors: Bernard Dureault, Jacques Lordet, Claude Bonnejean
  • Publication number: 20120238848
    Abstract: Embodiments of the present invention relate to a system and method for practicing spectrophotometry using light emitting nanostructures. Specifically, embodiments of the present invention include a physiologic sensor comprising a sensor body configured for placement adjacent pulsatile tissue of a patient, a first light emitting nanostructure device configured to emit light at a first wavelength through the pulsatile tissue, a second light emitting nanostructure device configured to emit light at a second wavelength through the pulsatile tissue, and a light detector configured to detect the light at the first wavelength and the light at the second wavelength after dispersion through the pulsatile tissue.
    Type: Application
    Filed: June 1, 2012
    Publication date: September 20, 2012
    Applicant: Nellcor Puritan Bennett LLC
    Inventors: Gilbert Hausmann, Michael P. O'Neil, Paul Mannheimer
  • Patent number: 6475339
    Abstract: A system and method for rapidly determining the pulp kappa number through direct measurement of the potassium permanganate concentration in a pulp-permanganate solution using spectrophotometry. Specifically, the present invention uses strong acidification to carry out the pulp-permanganate oxidation reaction in the pulp-permanganate solution to prevent the precipitation of manganese dioxide (MnO2). Consequently, spectral interference from the precipitated MnO2 is eliminated and the oxidation reaction becomes dominant. The spectral intensity of the oxidation reaction is then analyzed to determine the pulp kappa number.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: November 5, 2002
    Assignee: lnstitute of Paper Science and Technology, Inc
    Inventors: Xin-Sheng Chai, Jun Yong Zhu
  • Publication number: 20040109163
    Abstract: A system and method for measurement and analysis of a sample by absorption spectrophotometry is taught by the present invention. According to various embodiments, the invention utilizes a novel receptacle comprising of at plurality of layers including a transparent layer, a channel layer, and a reflective layer coupled to one another and allowing for fluid communication within and among the layers to allow for illumination by a light source and interrogation and analysis by a light measuring device. Examples of the light source and light measuring devices that could be used with the present invention include reflectance and/or fluorescence spectroscopy and a spectrometer, respectively. Measurement and analysis of a sample is compared to known values of constituents for comparison.
    Type: Application
    Filed: December 3, 2003
    Publication date: June 10, 2004
    Applicant: SpectRx, Inc.
    Inventors: Shabbir B. Bambot, Scott Kerr, Mark A. Samuels, Henry Grage, Gregory J. Newman
  • Publication number: 20190302007
    Abstract: A non-contact photoacoustic spectrophotometry system is configured to measure an absorption spectrum of a material. The system includes a modulated light source such as tunable pulsed laser that generates laser pulses to produce photoacoustic signals in the material. A non-contact detector monitors the surface of the container for the material. The detector includes a second light source, such as a continuous wave laser, focused on the surface of the container, and transmits reflected light to an interferometer, for example, a Sagnac interferometer. The interferometer produces an interference signal from the received light that is proportional to the acoustic pressure, which is transmitted to a computer to calculate an absorption coefficient. Using a plurality of wavelengths from the tunable pulsed laser, an absorption spectrum may be generated.
    Type: Application
    Filed: March 28, 2019
    Publication date: October 3, 2019
    Applicant: University of Washington
    Inventors: Ivan Pelivanov, Matthew O'Donnell, Elena Petrova, Soon Joon Yoon
  • Patent number: 8219170
    Abstract: Embodiments of the present invention relate to a system and method for practicing spectrophotometry using light emitting nanostructures. Specifically, embodiments of the present invention include a physiologic sensor comprising a sensor body configured for placement adjacent pulsatile tissue of a patient, a first light emitting nanostructure device configured to emit light at a first wavelength through the pulsatile tissue, a second light emitting nanostructure device configured to emit light at a second wavelength through the pulsatile tissue, and a light detector configured to detect the light at the first wavelength and the light at the second wavelength after dispersion through the pulsatile tissue.
    Type: Grant
    Filed: September 20, 2006
    Date of Patent: July 10, 2012
    Assignee: Nellcor Puritan Bennett LLC
    Inventors: Gilbert Hausmann, Michael P. O'Neil, Paul Mannheimer
  • Patent number: 5953118
    Abstract: A multiplexed spectrophotometry apparatus, including a rotary multiplexer fitted with a plurality of fiber terminals, a spectrophotometer mounted to the multiplexer and rotatable therewith, and a programmable on-board computer. The spectrophotometer includes precision optics, a charge coupled device (CCD) detector, electronics, and a cooling system, all contained in a compact, streamlined housing that is shaped to promote the radiation of heat from the spectrophotometer and thereby prevent excessive heating during operation of the apparatus. The spectrophotometer is mounted directly to the multiplexer so that any selected terminal can readily be brought into precise, reproducible alignment with the spectrophotometer input. All components of the apparatus are contained in a compact housing adapted for either rack-mounted or bench-top use.
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: September 14, 1999
    Assignee: Equitech Int'l Corporation
    Inventors: Patrick E. O'Rourke, William R. Toole, Jr.
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