Search Patents
  • Monoclonal Antibodies for Treatment of Cancer
    Publication number: 20100111975
    Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast cancer, lung cancer, gastric cancer, ovarian cancer, and hepatocellular cancer.
    Type: Application
    Filed: March 14, 2008
    Publication date: May 6, 2010
    Inventors: Ugur Sahin, Michael Koslowski, Ozlem Tureci
  • Monoclonal Antibodies for Treatment of Cancer
    Publication number: 20130156782
    Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast cancer, lung cancer, gastric cancer, ovarian cancer, and hepatocellular cancer.
    Type: Application
    Filed: December 11, 2012
    Publication date: June 20, 2013
    Inventors: Ugur Sahin, Michael Koslowski, Ozlem Tureci
  • Identification of Tumor-Associated Antigens for Diagnosis and Therapy
    Publication number: 20140017254
    Abstract: The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
    Type: Application
    Filed: July 19, 2013
    Publication date: January 16, 2014
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski, Dirk Usener
  • Antibodies Against Claudin 18.2 Useful in Cancer Diagnosis
    Publication number: 20150147763
    Abstract: The invention relates to antibodies directed against an epitope located within the C-terminal portion of CLDN18.2 which are useful, for example, in diagnosing cancer and/or in determining whether cancer cells express CLDN18.2.
    Type: Application
    Filed: May 6, 2013
    Publication date: May 28, 2015
    Inventors: Ugur Sahin, Özlem Türeci, Rita Mitnacht-Kraus, Stefan Wöll
  • Identification of Tumor-Associated Markers for Diagnosis and Therapy
    Publication number: 20110104147
    Abstract: The present technology relates to genetic products the expression of which is associated with cancer diseases. The present technology also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
    Type: Application
    Filed: April 22, 2010
    Publication date: May 5, 2011
    Inventors: Ugur Sahin, Özlem Türeci, Michael Koslowski
  • Identification of Tumor-Associated Markers for Diagnosis and Therapy
    Publication number: 20140134165
    Abstract: The present technology relates to genetic products the expression of which is associated with cancer diseases. The present technology also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
    Type: Application
    Filed: January 20, 2014
    Publication date: May 15, 2014
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • Identification of Tumor-Associated Antigens for Diagnosis and Therapy
    Publication number: 20110189179
    Abstract: The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
    Type: Application
    Filed: April 13, 2011
    Publication date: August 4, 2011
    Inventors: Ugur Sahin, Özlzem Türeci, Michael Koslowski, Dirk Usener
  • Identification of Tumor-Associated Antigens for Diagnosis and Therapy
    Publication number: 20090202530
    Abstract: The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
    Type: Application
    Filed: September 6, 2006
    Publication date: August 13, 2009
    Inventors: Ugur Sahin, Özlem Türeci, Michael Koslowski, Dirk Usener
  • Genetic Products Differentially Expressed In Tumors And The Use Thereof
    Publication number: 20090208498
    Abstract: The present technology relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for the expressed products. An embodiment of the present technology also relates to the therapy and diagnosis of disease in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors, and to the nucleic acids coding for the polypeptides, peptides and proteins.
    Type: Application
    Filed: April 14, 2009
    Publication date: August 20, 2009
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • GENETIC PRODUCTS DIFFERENTIALLY EXPRESSED IN TUMORS AND USE THEREOF
    Publication number: 20090081215
    Abstract: The invention relates to the identification of genetic products that are expressed in association with a tumor and the nucleic acid coding therefor. The invention relates to the therapy and diagnosis of diseases in which said genetic products that are expressed in association with a tumor are expressed in an aberrant manner. The invention also relates to proteins, polypeptides, and peptides which are expressed in association with a tumor and the nucleic acids coding therefor.
    Type: Application
    Filed: August 25, 2008
    Publication date: March 26, 2009
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • Genetic Products Differentially Expressed In Tumors And The Use Thereof
    Publication number: 20140186338
    Abstract: The present technology relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for the expressed products. An embodiment of the present technology also relates to the therapy and diagnosis of disease in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors, and to the nucleic acids coding for the polypeptides, peptides and proteins.
    Type: Application
    Filed: October 1, 2013
    Publication date: July 3, 2014
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • IDENTIFICATION OF TUMOR-ASSOCIATED MARKERS FOR DIAGNOSIS AND THERAPY
    Publication number: 20120070430
    Abstract: The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
    Type: Application
    Filed: April 22, 2010
    Publication date: March 22, 2012
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • Monoclonal Antibodies Against Claudin-18 for Treatment of Cancer
    Publication number: 20100166779
    Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD1 8, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, cancer of the gallbladder, and the metastases thereof.
    Type: Application
    Filed: May 27, 2008
    Publication date: July 1, 2010
    Inventors: Ugur Sahin, Ozlem Tureci, Gunda Brandenburg, Dirk Usener
  • GENETIC PRODUCTS DIFFERENTIALLY EXPRESSED IN TUMORS AND THE USE THEREOF
    Publication number: 20120258091
    Abstract: The invention relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for the expressed products. An embodiment of the invention also relates to the therapy and diagnosis of disease in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors, and to the nucleic acids coding for the polypeptides, peptides and proteins.
    Type: Application
    Filed: November 15, 2011
    Publication date: October 11, 2012
    Applicant: GANYMED PHARMACEUTICALS AG
    Inventors: Ugur Sahin, Özlem Türeci, Michael Koslowski
  • Identification of Surface-Associated Antigens for Tumor Diagnosis and Therapy
    Publication number: 20090214550
    Abstract: The invention relates to identifying tumor-associated genetic products and encoding nucleic acids thereof. A therapy and diagnosis of diseases in which the tumor-associated genetic products are aberrantly expressed, proteins, polypeptides and peptides which are expressed in association with tumor and the encoding nucleic acids for said proteins, polypeptides and peptides are also disclosed.
    Type: Application
    Filed: March 23, 2006
    Publication date: August 27, 2009
    Inventors: Ugur Sahin, Özlem Türeci, Michael Koslowski, Gerd Helftenbein, Dirk Usener, Volker Schlüter
  • MONOCLONAL ANTIBODIES AGAINST CLAUDIN-18 FOR TREATMENT OF CANCER
    Publication number: 20090169547
    Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
    Type: Application
    Filed: November 24, 2006
    Publication date: July 2, 2009
    Inventors: Ugur Sahin, Ozlem Tureci, Dirk Usener, Stefan Fritz, Cristoph Uherek, Gunda Brandenburg, Harald-Gerhard Geppert, Anja Kristina Schroder, Philippe Thiel
  • IDENTIFICATION OF SURFACE-ASSOCIATED ANTIGENS FOR TUMOR DIAGNOSIS AND THERAPY
    Publication number: 20140017679
    Abstract: The invention relates to identifying tumor-associated genetic products and encoding nucleic acids thereof. A therapy and diagnosis of diseases in which the tumor-associated genetic products are aberrantly expressed, proteins, polypeptides and peptides which are expressed in association with tumor and the encoding nucleic acids for said proteins, polypeptides and peptides are also disclosed.
    Type: Application
    Filed: April 17, 2013
    Publication date: January 16, 2014
    Applicant: BioNTech AG
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski, Gerd Helftenbein, Dirk Usener, Volker Schluter
  • Genetic Products Which are Differentially Expressed in Tumors and Use Thereof
    Publication number: 20100203040
    Abstract: The invention relates to the identification of genetic products expressed in association with tumours and to coding nucleic acids for said products. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are aberrantly expressed in association with tumours, proteins, polypeptides and peptides which are expressed in association with tumours and to the coding nucleic acids for said proteins, polypeptides and peptides.
    Type: Application
    Filed: September 10, 2004
    Publication date: August 12, 2010
    Inventors: Oezlem Tuereci, Ugur Sahin, Michael Koslowski
  • Genetic Products Differentially Expressed in Tumors and the Use Thereof
    Publication number: 20080166350
    Abstract: According to the invention, gene products expressed in a tumor-associated manner and the nucleic acids coding therefor were identified. The invention relates to the therapy and diagnosis of diseases wherein said gene products expressed in a tumor-associated manner are aberrantly expressed. The invention also relates to proteins, polypeptides and peptides which are expressed in a tumor associated manner and to nucleic acids coding therefor.
    Type: Application
    Filed: May 18, 2005
    Publication date: July 10, 2008
    Applicant: Ganymed Pharmaceuticals AG
    Inventors: Ozlem Tureci, Ugur Sahin, Michael Koslowski
  • MONOCLONAL ANTIBODIES AGAINST CLAUDIN-18 FOR TREATMENT OF CANCER
    Publication number: 20120164160
    Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD1 8, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
    Type: Application
    Filed: November 29, 2011
    Publication date: June 28, 2012
    Applicants: JOHANNES GUTENBERG-UNIVERSITAT MAINZ, GANYMED PHARMACEUTICALS AG
    Inventors: Ugur Sahin, Özlem Türeci, Dirk Usener, Stefan Fritz, Christoph Uherek, Gunda Brandenburg, Harald-Gerhard Geppert, Anja Kristina Schröder, Phillippe Thiel