Abstract: A stabilized solid oral pharmaceutical composition comprised of iodide and iodate as the active agents in the presence of one or more pharmaceutical excipients and a method for preparing these stabilized compositions.
Type:
Grant
Filed:
February 26, 1999
Date of Patent:
June 19, 2001
Assignee:
Symbollon Corporation
Inventors:
Yongjun Duan, Kirk Dinehart, John Hickey, Jack Kessler
Abstract: A method for forming an iodine disinfecting solution that continuously generates free molecular iodine at a controlled average rate of at least 0.2 ppm per hour over a sustained and extended time period. The method involves combining persulfate anions and iodide anions in sufficient quantity in an aqueous medium having a resulting pH of less than about 6.5 so as to create an iodine generating capacity in said aqueous medium of between 1.5 and 6.5 with a generated concentration of at least 5 ppm of free molecular iodine and maintaining this concentration over the course of the extended time period.