Search Patents
  • Heterocyclic ester and amide hair growth compositions and uses
    Publication number: 20010041733
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic esters or amides.
    Type: Application
    Filed: June 14, 2001
    Publication date: November 15, 2001
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Heterocyclic thioester and ketone hair growth compositions and uses
    Publication number: 20020016341
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic thioesters and ketones.
    Type: Application
    Filed: June 12, 2001
    Publication date: February 7, 2002
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Pyrrolidine derivative hair growth compositions and uses
    Publication number: 20010049381
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pyrrolidine derivatives.
    Type: Application
    Filed: June 29, 2001
    Publication date: December 6, 2001
    Applicant: GPL NIL Holdings, Inc.,
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Pyrrolidine derivative hair growth compositions and uses
    Patent number: 6943187
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pyrrolidine derivatives.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: September 13, 2005
    Assignee: GPI Nil Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Heterocyclic thioester and ketone hair growth compositions and uses
    Patent number: 6274602
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic thioesters and ketones.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: August 14, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • N-oxide of heterocyclic ester, amide, thioester, or ketone hair growth compositions and uses
    Patent number: 6429215
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using an N-oxide of a heterocyclic ester, amide, thioester, or ketone.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: August 6, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Rotamase enzyme activity inhibitors
    Patent number: 7056935
    Abstract: This invention relates to methods of using neurotrophic compounds having an affinity for FKBP-type immunophilins to stimulate or promote neuronal growth or regeneration and to prevent neuronal degeneration.
    Type: Grant
    Filed: March 14, 2001
    Date of Patent: June 6, 2006
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Heterocyclic ester and amide hair growth compositions and uses
    Patent number: 6274617
    Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic esters or amides.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: August 14, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Joseph P. Steiner, Gregory S. Hamilton
  • Heterocyclic ketone and thioester compounds and uses
    Publication number: 20040106652
    Abstract: This invention relates to neurotrophic, low molecular weight, small molecule heterocyclic ketone and thioester compounds, compositions containing the same, and the use of such compounds for treating neurological disorders, including physically damaged nerves and neurodegenerative diseases.
    Type: Application
    Filed: July 10, 2003
    Publication date: June 3, 2004
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li
  • Cyclic ester or amide derivatives
    Patent number: 6462072
    Abstract: This invention relates to low molecular weight, small molecule cyclic esters and amides having an affinity for FKBP-type immunophilins, pharmaceutical compositions comprising the same, and methods of using the same to effect a neuronal activity.
    Type: Grant
    Filed: September 21, 1998
    Date of Patent: October 8, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, David C. Limburg
  • Small molecule carbamates or ureas for vision and memory disorders
    Patent number: 6395758
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using small molecule carbamates and ureas.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: May 28, 2002
    Assignee: GPI Nil Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Small molecule inhibitors of rotamase enzyme activity
    Patent number: 6140357
    Abstract: This invention relates to neurotrophic N-glyoxylprolyl ester compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
    Type: Grant
    Filed: April 8, 1997
    Date of Patent: October 31, 2000
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Joseph P. Steiner
  • Heterocyclic esters or amides for vision and memory disorders
    Patent number: 7338976
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic esters and amides.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: March 4, 2008
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Gregory S. Hamilton, Joseph P. Steiner
  • Pyrrolidine derivatives for vision and memory disorders
    Patent number: 6218423
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using pyrrolidine derivatives.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: April 17, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Small molecule inhibitors of rotamase enzyme activity
    Patent number: 6291510
    Abstract: This invention relates to neurotrophic compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
    Type: Grant
    Filed: May 7, 1998
    Date of Patent: September 18, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Joseph P. Steiner
  • Heterocyclic thioesters and ketones
    Patent number: 5990131
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule heterocyclic thioesters and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: August 1, 1997
    Date of Patent: November 23, 1999
    Assignee: Gpi Nil Holdings Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li
  • Small molecule inhibitors of rotamase enzyme activity
    Patent number: 5795908
    Abstract: This invention relates to neurotrophic N-glyoxyl-prolyl ester compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
    Type: Grant
    Filed: January 23, 1997
    Date of Patent: August 18, 1998
    Assignee: GPI Nil Holdings, Inc.
    Inventors: Gregory S. Hamilton, Joseph P. Steiner
  • Heterocyclic thioesters
    Patent number: 5786378
    Abstract: This invention relates to neurotrophic low molecular weight, small molecule heterocyclic thioesters and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
    Type: Grant
    Filed: September 25, 1996
    Date of Patent: July 28, 1998
    Assignee: GPI Nil Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li
  • Heterocyclic ketone and thioester compounds and uses
    Patent number: 6218424
    Abstract: This invention relates to neurotrophic, low molecular weight, small molecule heterocyclic ketone and thioester compounds, compositions containing the same, and the use of such compounds for treating neurological disorders, including physically damaged nerves and neurodegenerative diseases.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: April 17, 2001
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li
  • N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders
    Patent number: 6399648
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using N-Oxides of heterocyclic esters, amides, thioesters, or ketones
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: June 4, 2002
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner