Abstract: A bisamide-bisthiol ligand containing fatty acid substituted thiol useful for producing Tc-labelled radiodiagnostic imaging agents is described. The ligand forms a complex with the radionuclide .sup.99m Tc suitable for administration as a radiopharmaceutical to obtain images of the heart for diagnosis of myocardial disfunction.
Type:
Grant
Filed:
April 26, 1985
Date of Patent:
May 24, 1988
Assignees:
President and Fellows of Harvard College, Children's Medical Center Corp., Massachusetts Institute of Technology
Inventors:
Alun G. Jones, John Lister-James, Alan Davison