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  • Intermediates for the hemisynthesis of taxanes and preparation processes therefor
    Patent number: 7432383
    Abstract: The present invention generally relates to at least one precursor compound and derivatives thereof, a process for preparing a taxane, and a baccatin derivative.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: October 7, 2008
    Assignee: Societe d'Etude et de Recherche En Ingenierie Pharmaceutique-Seripharm
    Inventors: Luc Chanteloup, Bruno Chauveau, Christina Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin
  • Intermediary compounds for the hemisynthesis of taxanes and preparation processes therefor
    Patent number: 6265587
    Abstract: The present invention relates to new intermediates for the semisynthesis of taxanes and their preparation processes. It relates to derivatives of oxazolidines or oxazolidinones, as well as to new derivatives of baccatine III. The general process for the synthesis of taxanes according to the invention enables to obtain a product such as PACLITAXEL in only five steps from products available in the market, compared to nine steps in general, for processes of the prior art.
    Type: Grant
    Filed: April 27, 1998
    Date of Patent: July 24, 2001
    Assignee: Societe d'Etude et de Recherche en Ingenierie Pharmaceutique Seripharm
    Inventors: Luc Chanteloup, Bruno Chauveau, Christine Corbin, Robert Dhal, Sonia Le Guen, Arnaud Lamy, Antoine Leze, Jean-Pierre Robin