Search Patents
  • Publication number: 20080306282
    Abstract: Novel forms of [R—(R*,R*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease.
    Type: Application
    Filed: July 11, 2005
    Publication date: December 11, 2008
    Inventors: Joseph F. Krzyzaniak, George M. Laurence, Aeri Park, Kevin J. Quackenbush, Marie L. Reynolds, Peter R. Rose, Timothy A. Woods
  • Patent number: 8026376
    Abstract: Novel forms of [R-(R*,R*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4 -[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease.
    Type: Grant
    Filed: July 11, 2005
    Date of Patent: September 27, 2011
    Assignee: Pfizer, Inc.
    Inventors: Joseph F. Krzyzaniak, George M. Laurence, Aeri Park, Kevin J. Quackenbush, Marie L. Reynolds, Peter R. Rose, Timothy A. Woods
  • Publication number: 20110301358
    Abstract: Novel forms of [R—(R*,R*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXVV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPII) and Alzheimer's disease.
    Type: Application
    Filed: August 22, 2011
    Publication date: December 8, 2011
    Applicant: Pfizer Inc.
    Inventors: Joseph F. Krzyzaniak, George M. Laurence, Aeri Park, Kevin J. Quackenbush, Marie L. Reynolds, Peter R. Rose, Timothy A. Woods