Search Patents
  • Patent number: 6167304
    Abstract: Apparatus and method for manipulating the nervous system of a subject by applying to the skin a pulsing external electric field which, although too weak to cause classical nerve stimulation, modulates the normal spontaneous spiking patterns of certain kinds of afferent nerves. For certain pulse frequencies the electric field stimulation can excite in the nervous system resonances with observable physiological consequences. Pulse variability is introduced for the purpose of thwarting habituation of the nervous system to the repetitive stimulation, or to alleviate the need for precise tuning to a resonance frequency, or to control pathological oscillatory neural activities such as tremors or seizures. Pulse generators with stochastic and deterministic pulse variability are disclosed, and the output of an effective generator of the latter type is characterized.
    Type: Grant
    Filed: June 17, 1999
    Date of Patent: December 26, 2000
    Inventor: Hendricus G. Loos
  • Patent number: 6081744
    Abstract: Apparatus and method for manipulating the nervous system of a subject through afferent nerves, modulated by externally applied weak fluctuating electric fields, tuned to certain frequencies such as to excite a resonance in neural circuits. Depending on the frequency chosen, excitation of such resonances causes in a human subject relaxation, sleepiness, sexual excitement, or the slowing of certain cortical processes. The electric field used for stimulation of the subject is induced by a pair of field electrodes charged to opposite polarity and placed such that the subject is entirely outside the space between the field electrodes. Such configuration allows for very compact devices where the field electrodes and a battery-powered voltage generator are contained in a small casing, such as a powder box. The stimulation by the weak external electric field relies on frequency modulation of spontaneous spiking patterns of afferent nerves.
    Type: Grant
    Filed: July 17, 1998
    Date of Patent: June 27, 2000
    Inventor: Hendricus G. Loos
  • Patent number: 5899922
    Abstract: Apparatus and method for manipulating the nervous system of a subject through afferent nerves, modulated by an externally applied weak electric field. The field frequency is to be chosen such that the modulation causes excitation of a sensory resonance. The resonances found so far include one near 1/2 Hz which affects the autonomic nervous system, and a resonance near 2.4 Hz that causes slowing of certain cortical processes. Excitation of the 1/2 Hz autonomic resonance causes relaxation, sleepiness, ptosis of the eyelids, or sexual excitement, depending on the precise frequency used. The weak electric field for causing the excitation is applied to skin areas away from the head of the subject, such as to avoid substantial polarization current densities in the brain. Very weak fields suffice for bringing about the physiological effects mentioned. This makes it possible to excite sensory resonances with compact battery powered devices that have a very low current consumption.
    Type: Grant
    Filed: November 14, 1997
    Date of Patent: May 4, 1999
    Inventor: Hendricus G. Loos
  • Patent number: 5782874
    Abstract: Apparatus and method for manipulating the nervous system of a subject through afferent nerves, modulated by externally applied weak fluctuating electric fields, tuned to certain frequencies such as to excite a resonance in certain neural circuits. Depending on the frequency chosen, excitation of such resonances causes relaxation, sleepiness, sexual excitement, or the slowing of certain cortical processes. The weak electric field for causing the excitation is applied to skin areas away from the head of the subject, such as to avoid substantial polarization current densities in the brain. By exploiting the resonance phenomenon, these physiological effects can be brought about by very weak electric fields produced by compact battery-operated devices with very low current assumption. The fringe field of doublet electrodes that form a parallel-plate condenser can serve as the required external electric field to be administered to the subject's skin.
    Type: Grant
    Filed: January 24, 1997
    Date of Patent: July 21, 1998
    Inventor: Hendricus G. Loos