Abstract: A renal treatment fluid priming method includes priming an extracorporeal circuit connected to a patient with a physiologically compatible fluid, the extracorporeal circuit including an arterial line, a venous line and blood compartment of a blood filter; and pumping from a renal treatment fluid line in communication with the blood filter (i) pulling blood from the patient through the arterial line to flush the physiologically compatible fluid through the arterial line and the blood filter compartment into the renal treatment fluid line and (ii) pulling blood from the patient through the venous line to flush the physiologically compatible fluid through the venous line and the blood filter compartment into the renal treatment fluid line, such that a greater volume of blood is pulled from the patient via (i) and (ii) than a volume of the extracorporeal circuit.

Abstract: A portable peritoneal dialysis apparatus having a side-hinged, inclined door for enclosing a disposable cassette that seals tightly shut using air pressure which imposes a safety interlock, a cassette with its inlet/outlet tube exclusively along the lower edge so that the connected lines can hang straight, a circumferential channel defined in the cassette, and a pneumatic system for sealing the membranes of both the pump chamber diaphragms and the pressure sensor diaphragms in the cassette to the respective mating pistons and pressure sensors in the cycler. In addition a system for draining patient line fluid to an empty solution bag is disclosed.

Abstract: A hemodialysis system including (i) an instrument; (ii) first and second peristaltic dialysate pumps operated by the instrument; (iii) a cassette including a rigid structure and first and second dialysate pumping tubes carried by the rigid structure; and (iv) a mechanism configured to initially allow the cassette to be accepted by the dialysis instrument after which the mechanism engages the first and second dialysate pumping tubes for operation with the first and second peristaltic dialysate pumps.

Abstract: Apparatuses, devices, systems and methods for detecting access disconnection are provided. In one embodiment, a medical fluid system includes (i) a medical fluid machine and (ii) a device operable with the medical fluid machine, the device configured to provide electrical contact with a medical fluid, the device including (a) a tube used during dialysis therapy through which the medical fluid can flow, and (b) a conductive element configured to self-sealingly pierce the tube, the conductive element having a first portion exposed to the medical fluid and a second portion external to the tube.

Abstract: A peritoneal dialysis system includes a logic implementer configured to: (i) generate a number of peritoneal dialysis therapy regimens that meet at least one therapy target input; (ii) accept a filter input; and (iii) filter the generated therapy regimens according to the filter input to refine the number of therapy regimens available for selection.

Abstract: A hemodialysis system includes (i) blood tubing; (ii) a peristaltic blood pump contacting the blood tubing to pump blood through the blood tubing; (iii) a dialyzer in fluid communication with the blood tubing; (iv) first and second peristaltic dialysate pumps; (v) a dialysate heater; (vi) a plurality of pinch valves; and (vii) a cassette including a rigid structure, a heating portion, first and second dialysate pumping tubes, and a plurality of incoming tubes, the rigid structure when the cassette is mounted for operation orienting (a) the heating portion adjacent to the dialysate heater so that dialysate can be heated by the dialysate heater, (b) the first and second dialysate pumping tubes adjacent to the first and second peristaltic dialysate pumps, and (c) the plurality of incoming tubes adjacent to the plurality of pinch valves to enable the tubes to be individually closed by the pinch valves.

Abstract: A peritoneal dialysis system includes a logic implementer configured to: (i) accept at least one therapy target input; (ii) accept at least one patient transport characteristic input; (iii) accept at least one solution input; (iv) accept at least one fluid volume input; (v) accept at least one therapy time input, at least one of the inputs (ii) to (v) including an input range; and (vi) generate each therapy regimen using the inputs of (ii), (iii), (iv) and (v), including each of the possibilities within the at least one input range, that satisfy the at least one therapy target input.

Abstract: A kidney failure therapy system includes: (a) a dilaysate supply; (b) at least one valve actuator; (c) at least one pump actuator; and (d) a disposable unit including first and second flexible sheets sealed together for form: (i) at least one flow path configured to be placed in fluid communication with the dilaysate supply; and operable with the at least one valve actuator; and (ii) at least one pumping portion configured to operate with the at least one pump actuator.