Patents Represented by Attorney Dara L. Dinner
  • Patent number: 7576096
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: August 18, 2009
    Assignee: Glaxo Group Limited
    Inventors: Jakob Busch-Petersen, Michael R. Palovich, Zehong Wan, Hongxing Yan, Chongjie Zhu
  • Patent number: 7572790
    Abstract: Compound of formula (I): or pharmaceutically acceptable derivatives thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: April 7, 2004
    Date of Patent: August 11, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Nicola Mary Aston, Paul Bamborough, Katherine Louise Jones, Vipulkumar Kantibhai Patel, Stephen Swanson, Ann Louise Walker
  • Patent number: 7563803
    Abstract: Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.
    Type: Grant
    Filed: July 9, 2007
    Date of Patent: July 21, 2009
    Assignee: Glaxo Group Limited
    Inventors: Zehong Wan, Hongxing Yan, Michael R. Palovich, Dramane I. Laine
  • Patent number: 7550480
    Abstract: Novel substituted 1,5,7-trisubstituted-1,8-napthyridin-2(1H)-one compounds; 1,5,7 trisubstituted-1,6-napthyridine-2-(1H)-one compounds and 1,5,7-trisubstituted quinoline-2(1H)-one compounds, processes for the preparation thereof, the use thereof in treating CSBP/p38 kinase mediated diseases and pharmaceutical compositions for use in such therapy.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: June 23, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Jeffrey Charles Boehm, James Francis Callahan, Ralph F. Hall, Xichen Lin, Katherine Louise Widdowson
  • Patent number: 7521072
    Abstract: A delivery system and method for delivering soluble dietary fibers in a chewable tablet form which is palatable and demonstrates a high degree of consumer acceptability.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: April 21, 2009
    Assignee: CNS, Inc.
    Inventor: Jerome J. Licari
  • Patent number: 7514456
    Abstract: Compounds of formula (I): are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38.
    Type: Grant
    Filed: August 7, 2006
    Date of Patent: April 7, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Nicola Mary Aston, Paul Bamborough, Ann Louise Walker
  • Patent number: 7507747
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Grant
    Filed: October 15, 2004
    Date of Patent: March 24, 2009
    Assignee: Glaxo Group Limited
    Inventors: Michael R. Palovich, Zehong Wan, Chongjie Zhu
  • Patent number: 7498440
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Grant
    Filed: April 27, 2005
    Date of Patent: March 3, 2009
    Assignee: Glaxo Group Limited
    Inventors: Damane I. Laine, Michael R. Palovich, Brent W. McCleland, Christopher E. Neipp, Sonia M. Thomas
  • Patent number: 7495010
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: February 24, 2009
    Assignee: Glaxo Group Limited
    Inventors: Kristen E. Belmonte, Jakob Busch-Petersen, Dramane I. Laine, Michael R. Palovich
  • Patent number: 7488827
    Abstract: Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
    Type: Grant
    Filed: July 9, 2007
    Date of Patent: February 10, 2009
    Assignee: Glaxo Group Limited
    Inventors: Damane I. Laine, Michael R. Palovich, Brent W. McCleland, Christopher E. Neipp, Sonia M. Thomas
  • Patent number: 7479558
    Abstract: The present invention is directed to a novel method of preparing of 2,4,8-trisubstituted pyrido[2,3-d]pyrimidin-7-one pharmacophores of Formula (II) or (IIa) wherein G1 is CH2 or NH: G2 is CH or nitrogen; Rx is chloro, bromo, iodo, or O—S(O)2CF3; Rg is a C1-10alkyl; m is 0, or an integer having a value of 1, or 2; R3 is a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl C1-10 alkyl, aryl, arylC1-10 alkyl, heteroaryl, heteroarylC1-10 alkyl, heterocyclic or a heterocyclylC1-10 alkyl moiety, and wherein each of these moieties may be optionally substituted. which comprises reacting a compound of the formula: wherein Ry is chloro, bromo, iodo, O—S(O)2CF3; and Rg is a C1-10 alkyl; with a olefin forming reagent in a suitable base to yield a compound of Formula (II), or (IIa) wherein m=0 and oxidizing the sulphur as necessary or desired.
    Type: Grant
    Filed: March 24, 2006
    Date of Patent: January 20, 2009
    Assignee: Glaxo Group Limited
    Inventors: James F. Callahan, Jeffrey C. Boehm, Zehong Wan, Hongxing Yan, Xichen Lin
  • Patent number: 7452553
    Abstract: A delivery system and method for delivering soluble dietary fibers in a chewable tablet form which is palatable and demonstrates a high degree of consumer acceptability.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: November 18, 2008
    Assignee: CNS, Inc.
    Inventor: Jerome J. Licari
  • Patent number: 7432289
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: October 7, 2008
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Suzanne Joy Merrick, Kathryn Jane Smith, Ann Louise Walker
  • Patent number: 7425555
    Abstract: Compounds of formula (I): are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38.
    Type: Grant
    Filed: April 29, 2003
    Date of Patent: September 16, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Richard Martyn Angell, Paul Bamborough, Ian Robert Baldwin, Anne-Marie Li-Kwai-Cheung, Timothy Longstaff, Suzanne Joy Merrick, Kathryn Jane Smith, Stephen Swanson, Ann Louise Walker
  • Patent number: 7422758
    Abstract: A therapeutic formulation in the form of a beadlet, suitable for oral administration and adapted to provide immediate and sustained release of therapeutic material. Each beadlet comprises an extruded-spheronized inner core containing at least one medicament e.g. a slow release vitamin, an outer layer containing at least one medicament e.g. a fast release vitamin and a controlled release coating between the inner core and the outer layer which coating controls the release of the inner core medicament.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: September 9, 2008
    Assignees: GlaxoSmithKline Consumer Healthcare GmbH & Co. KG, Allphamed Pharbil Pharma GmbH
    Inventors: Juergen Block, Stefan Heim, Ralf Westerheide
  • Patent number: 7423042
    Abstract: This invention relates to a novel group of 8-Alkyl/Aryl-4-aryl-2-N-(alkylamino)-N?-substituted-N?-cyanoguanidino-8H-pyrido[2,3-d]pyrimidin-7-one compounds, processes for the preparation thereof, the use thereof in treating CSBP/p38 kinase mediated diseases and pharmaceutical compositions for use in such therapy.
    Type: Grant
    Filed: March 24, 2006
    Date of Patent: September 9, 2008
    Assignee: Glaxo Group Limited
    Inventors: Jeffrey C. Boehm, John J. Taggart
  • Patent number: 7396843
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: July 8, 2008
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Suzanne Joy Merrick, Ann Louise Walker
  • Patent number: 7393545
    Abstract: The present invention relates to a novel pharmaceutical composition and process for preparing swallowable rapidity disintegrating methylcellulose and lipstatin derivatives together in combination with a suitable diluent and excipients.
    Type: Grant
    Filed: June 24, 2003
    Date of Patent: July 1, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Bruce P. Daggy, Kenneth G. Mandel
  • Patent number: 7387803
    Abstract: A delivery system and method for delivering soluble dietary fibers in a chewable tablet form which is palatable and demonstrates a high degree of consumer acceptability.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: June 17, 2008
    Assignee: CNS, Inc.
    Inventor: Jerome J. Licari
  • Patent number: 7384946
    Abstract: Novel dimeric benzoazabicyclohepatane compounds, pharmaceutical compositions, processes for their preparation and use thereof in treating M3 muscarinic acetylcholine receptor mediated diseases are disclosed.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: June 10, 2008
    Assignee: Glaxo Group Limited
    Inventors: Jakob Busch-Petersen, Anthony W. J. Cooper, Dramane I. Laine, Brent W. McCleland, Michael R. Palovich