Patents Represented by Attorney Dara L. Dinner

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  • 2?-Methyl-5?-(1,3,4-oxadiazol-2-yl)-1,1?-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors
    Patent number: 7166623
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: January 23, 2007
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Paul Bamborough, George Stuart Cockerill, Kathryn Jane Smith, Ann Louise Walker
  • Multi-component pharmaceutical dosage form
    Patent number: 7163693
    Abstract: A multi-component pharmaceutical dosage form comprising a plurality of drug substance-containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: January 16, 2007
    Assignee: SmithKline Beecham plc
    Inventors: Allan J Clarke, Teodoro Fonio, Geoffrey Arthur Harris, Ron Kift, Donald Lightfoot, Shane McGinley, Thomas Ofsharick, Margaret Mary Szymczack
  • Biphenylcarboxylic amide derivatives as p38-kinase inhibitors
    Patent number: 7151118
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: December 19, 2006
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Ann Louise Walker
  • Rapidly disintegrating methylcellulose tablets
    Patent number: 7132114
    Abstract: The present invention relates to a novel pharmaceutical composition and process for preparing swallowable methylcellulose tablets that disintegrate rapidly and meet USP disintegration standards in 0.1N hydrochloric acid as well as water.
    Type: Grant
    Filed: April 16, 2002
    Date of Patent: November 7, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Bruce Daggy, Naresh I Mehta, Priyashri Nayak
  • Rapidly disintegrating methylcellulose tablets
    Patent number: 7125562
    Abstract: The present invention relates to a rapidly disintegrating tablet for oral administration. The tablet has a first phase and a second phase blended with the first phase. The first phase has a compacted mixture of methylcellulose having a viscosity of >1000 centipoise and a diluent. The methylcellulose is the sole active ingredient in the first phase. There is also a process for preparing a rapidly disintegrating tablet.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: October 24, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Bruce Daggy, Naresh I Mehta, Priyashri Nayak
  • Nicotinamide derivatives useful as p38 inhibitors.
    Patent number: 7125898
    Abstract: Compounds of formula (I): are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: October 24, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Nicola Mary Aston, Paul Bamborough, Ann Louise Walker
  • 3,4-Dihydro-(1H) quinazolin-2-one compounds as CSBP/P38 kinase inhibitors
    Patent number: 7053098
    Abstract: Novel substituted quinazoline compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: November 21, 2000
    Date of Patent: May 30, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Michael J. Bower, Jeffrey C. Boehm, Don Edgar Griswold, David C. Underwood
  • 3,4-dihydro-(1H)quinazolin-2-one compounds as CSBP/p38 kinase inhibitors
    Patent number: 7053099
    Abstract: Novel substituted quinazoline compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: November 21, 2000
    Date of Patent: May 30, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Michael J. Bower, Ralph Hall, Don Edgar Griswold, David C. Underwood
  • Compounds
    Patent number: 7026336
    Abstract: Compounds of formula (I) wherein X is O, CH2, S or NH, or the moiety X—R1 is hydrogen; V is CH or N; Y is NR10R11, NR10C(Z)NR10R11, NR10COOR11 or NR10SO2R11; Ar is phenyl or a 5- or 6-membered heteroaryl ring either of which may be optionally substituted; n is 0, 1, 2, 3 or 4; and R1, R2, R3, R4, R10 and R11 have the meanings given in the description; and pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: April 11, 2006
    Assignee: SmithKline Beecham p.l.c.
    Inventors: David Kenneth Dean, Peter John Lovell, Andrew Kenneth Takle
  • 3,4-dihydro-(1H)quinazolin-2-one compounds as CSBP/p38 kinase inhibitors
    Patent number: 6982270
    Abstract: Substituted quinazolinone compounds of formula (I) and compositions thereof for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: November 21, 2000
    Date of Patent: January 3, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Michael J. Bower, Jeffrey C. Boehm, Don Edgar Griswold, David C. Underwood
  • Pharmaceutical formulation comprising amoxycillin and clavulanate
    Patent number: 6977086
    Abstract: A pharmaceutical formulation in the form of a dry powder which comprises amoxycillin and clavulanate in a weight ratio of from 2:1 to about 16:1 and a pharmaceutically acceptable carrier or excipient and flavouring agents which provide a straw-berry flavour, further modified by the addition of extra components to add a creamy flavour or an extra fruity flavour.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: December 20, 2005
    Assignee: Laboratorie GlaxoSmithKline S.A.S.
    Inventors: Nathalie Claude Marianne Barges, Jacky Andre Gustave Mention
  • Liquid oral compositions comprising a calcium compound and an acidulant
    Patent number: 6908909
    Abstract: Acidic oral compositions having reduced tooth erosion characteristics, especially acid beverages such as fruit juice drink concentrates, or oral healthcare products such as mouthwashes, are prepared by adding a calcium compound to the acid composition so that the mol ratio of calcium to acid ranges from 0.3 to 0.8, and the pH of the composition, if necessary after adjustment with an alkali, is from 3.5 to 4.5.
    Type: Grant
    Filed: December 10, 2003
    Date of Patent: June 21, 2005
    Assignee: SmithKline Beecham plc
    Inventor: David Myatt Parker
  • Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
    Patent number: 6878386
    Abstract: Bacterial infections may be treated using a high dosage regimen of amoxycillin and potassium clavulanate. Preferably, the dosage is provided by a bilayer tablet.
    Type: Grant
    Filed: April 6, 2000
    Date of Patent: April 12, 2005
    Assignee: Beecham Pharmaceuticals (Pte) Limited
    Inventors: Creighton P. Conley, John A. Roush, Kevin H. Storm
  • Pyridin-4-YL or pyrimidin-4-YL substituted pyrazines
    Patent number: 6861417
    Abstract: Novel pyridin-4-yl or pyrimidin-4-yl substituted pyrazine compounds and compositions for use in therapy.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: March 1, 2005
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Ralph F. Hall, Jeffrey C. Boehm
  • Substituted imidazole compounds
    Patent number: 6858617
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as ERK/MAP inhibitors of ERK/MAP mediated diseases.
    Type: Grant
    Filed: June 2, 2003
    Date of Patent: February 22, 2005
    Assignee: SmithKline Beecham Corporation
    Inventor: Jerry L. Adams
  • Tablet containing a coated core
    Patent number: 6838094
    Abstract: A tablet formulation which comprises a core containing a pharmaceutically active material, coated with a release retarding coating, surrounded by a casing layer which includes a second pharmaceutically active material.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: January 4, 2005
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Francis Walter Grimmett, Nigel Philip McCreath Davidson
  • Process and apparatus for producing particles using a supercritical fluid
    Patent number: 6830714
    Abstract: A process, and a suitable apparatus, for production of particles of a material in which stream of a dispersion of the material in a solvent and a stream of a compressible fluid antisolvent substance are mixed under conditions such that the substance is in compressible fluid antisolvent state. The mixture then flows along a conduit (17) toward an orifice (18), from which it flows into a downstream region in which the compressible fluid antisolvent substance decompresses and the material is isolated in a particulate state. Preferably the antisolvent substance is a supercritical fluid. The process and apparatus can generate a co-formulation of the material with additives which can be introduced in a suitable aqueous or solvent based carrier vehicle.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: December 14, 2004
    Assignee: SmithKline Beecham plc
    Inventors: Petrus Paulus Cornelis Avontuur, David Roy Merrifield, Andrew Robert Souter, Christopher Edmund Valder, John Peter Warr
  • Composition comprising amoxicillin and potassium clavulanate
    Patent number: 6783773
    Abstract: Bacterial infections may be treated using a high dosage regimen of amoxicillin and potassium clavulanate. Preferably, the dosage is provided by a bilayer tablet.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: August 31, 2004
    Assignee: Beecham Pharmaceuticals (Pte) Limited
    Inventors: Kevin H. Storm, Creighton P. Conley, John A. Roush
  • Hinged container top
    Patent number: D506388
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: June 21, 2005
    Assignee: SmithKline Beecham Corporation
    Inventor: James L. Pitassi
  • Capsule link
    Patent number: D516714
    Type: Grant
    Filed: November 26, 2002
    Date of Patent: March 7, 2006
    Assignee: SmithKline Beechan p.l.c
    Inventors: Stephen Mark McAllister, Brian Hewitt