Abstract: The invention relates to nucleic acid molecules coding for a tumor rejection antigen precursor. Specifically, the tumor rejection antigen precursor, or "TRAP", is processed into at least one tumor rejection antigen, which is presented by HLA-A2 molecules. Ramifications of the discovery are also set forth.

Abstract: This invention relates to methods of reducing the effects of colon cancer tumors. Various agents are conjugated to monoclonal antibodies which are specific for colon cancer cells. The conjugates are administered to patients having colon cancer such that the effects of the cancer are reduced.

Abstract: The present invention is directed to a novel protein tyrosine kinase comprising a polypeptide having multiple protein kinase catalytic domains and, more particularly, two kinase catalytic domains and to genetic sequences encoding same. Two such kinases are described and designated JAK1 and JAK2.

Abstract: The invention concerns a binding matrix containing a carrier material with an oxidic surface and a solid phase reactant covalently bound thereto via anchor groups which is capable of binding to at least one free reaction partner, which is characterized in that the solid phase reactant forms a diluted and essentially laterally homogeneous binding layer on the surface of the carrier material and that the anchor groups are silane groups and are linked to the solid phase reactant via a spacer molecule.

Abstract: In a vacuum treatment system for applying thin layers to substrates (2, 2', . . . ) such as headlight reflectors, with several treatment (8, 9, 10) and/or inward and outward transfer lock stations (20) supported on a stationary vacuum chamber wall (16, 16', . . . ) and with a rotatably supported internal cylinder (14), which is enclosed by the vacuum chamber wall and carries the substrate chambers (3-6), openings (24-27) are provided in the vacuum chamber wall (16, 16', . . . ), with which the substrate chambers (3-6) can be aligned and through which the treatment agents can be allowed to act on the substrates (2, 2', . . .

Abstract: Isolated nucleic acid molecules encoding polysialyl transferases, and the polysialyl transferases themselves are disclosed. SEQ ID NOS: 1, 2, 7 and 8 present examples of these. The nucleic acid molecules and the proteins can be used diagnostically or therapeutically. Additionally, antisense oligonucleotides and antibodies are described, which can also be used diagnostically or therapeutically.

Abstract: The invention involves cytolytic T cell lines which are specific for complexes of HLA-B44 molecules and nonamers which bind to these.

Abstract: The invention relates to the identification of complexes of human leukocyte antigen molecules and tyrosinase derived peptides on the surfaces of abnormal cells. The therapeutic and diagnostic ramifications of this observation are the subject of the invention.

Abstract: The invention relates to the identification of complexes of human leukocyte antigen molecules and tyrosinase derived peptides on the surfaces of abnormal cells. The therapeutic and diagnostic ramifications of this observation are the subject of the invention.

Abstract: A reaction-formed moulded ceramic body containing mullite is described which is obtainable by heat treating a body moulded from a finely dispersed powder mixture of aluminium, Al.sub.2 O.sub.3 and a material containing Si in an atmosphere containing oxygen. Due to their properties, in particular their low shrinkage of 0 to 4% on average, the moulded bodies are very well suited for use as wear-resistant and/or high temperature-resistant components in the construction of machines, apparatuses and motors, as a cutting tool, as a component for bearings and/or seals and as a functional part in electronic instruments.

Abstract: A method, an apparatus, and an integrated system using the apparatus for measuring a concentration of odorant in odorized gas which is produced by adding the odorant to un-odorized gas comprised mainly of hydrocarbon gas. In a detection absorbance measuring step, there is obtaining detection odorized gas absorbance which is absorbance of the odorized gas relative to a detecting ultraviolet light having high absorbability to the odorant and low absorbability to the un-odorized gas. In a subsequent concentration deriving step, the odorant concentration in the odorized gas is derived from the detection odorized gas absorbance.

Abstract: The invention describes identification and isolation of molecules associated specifically with Hodgkin's Disease. Uses of the molecules are described as well.

Abstract: A photographic printing apparatus capable of printing, as an index print, an inlaid composite image having images of a plurality of frames of a film. An exposure device 10 of this printing apparatus includes an exposure controller 104 for controlling this exposure device 10 according to exposure conditions determined based on image information read from the film. The apparatus incorporates an index printer 40 for printing an inlaid composite image. An image information converter 103 is provided for producing, from the read image information, index-print image information corresponding to an image which is expected to be obtained on a photosensitive material if the material is exposed under the determined exposure conditions, and also for sending this index-print information to the index printer 40. A monitor 30 is provided for displaying the image information produced by the image information converter 103 for allowing checking thereof.

Abstract: Zirconium dioxide containing 2 to 40 vol. % of stabilizing oxides is embedded in the matrix material of a sintered molding consisting of an aluminum oxide/chromium oxide mixed crystal. The quantity of stabilizing oxides added is chosen so that the zirconium dioxide is predominantly tetragonal. The molar ratio of the zirconium dioxide containing the stabilizing oxides to the chromium oxide is between 1000:1 and 20:1 and the zirconium dioxide has a maximum particle size of 2 .mu.m.

Abstract: The movement of a vehicle is controlled by actuating actuators which apply a braking force to the wheels. For this purpose, the rotational speeds of the wheels, the steering angle and at least one of the lateral acceleration and the yawing movement of the vehicle are detected. A first module is configured so that the actuators are actuated by means of the actuation signals with the effect of controlling a first variable. The second module is configured so that signals for influencing the actuation signals are formed with the effect of controlling a second control variable. In order to obtain this second control variable, at least the variable which represents the steering angle is processed. The second controller component brings about a control of a variable which is determined at least as a function of the lateral movement or the yawing movement of the vehicle.

Abstract: A method for the treatment of cell mediated autoimmune disease is disclosed. The method involves administering interleukin-9 in an effective amount to the subject. Among the conditions treatable are thyroiditis and autoimmune diabetes.

Abstract: Semifinished products designed as composite bodies for electronic or opto-electronic semiconductor components are known. The composite bodies are made of a disk-shaped, transparent quartz glass substrate and a wafer made of a semiconductor material. The directly bonded surfaces of the quartz glass substrate and wafer are polished before being mutually bonded. In order to create a semifinished product that resists temperatures above 900.degree. C., such as those used to produce semiconductor circuits in industrially feasible times, without raising fears of a substantial reduction of the adhesive forces, chipping of the wafers away from each other or an undesirable deformation of the composite body, the substrate quartz glass is a synthetic quartz glass with at least 10.sup.14.0 poise viscosity at 950.degree. C. which does not fall below 10.sup.12 poise at 1050.degree. C.

Abstract: A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as DAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described.

Abstract: The invention relates to methods for making synthetic, photoreactive peptides and their use. A photoreactively labelled amino acid is incorporated into the peptide. The resulting peptide, when compared to the non-labelled form, is not impaired with respect to its ability to bind an MHC molecule.

Abstract: Disclosed are a process and a device for wetting pneumatically transported particles with a fluid where the fluid is sprayed by means of nozzles into a transport line through which the particles are flowing. The nozzles are installed in an area of the transport line which has a diffusor-like expansion in its cross section to insure that the particles are wetted uniformly and in a finely divided manner.