Abstract: The present invention is directed to compositions and methods related to soluble G-protein coupled receptors (sGPCR). In certain aspects the invention includes compositions and methods related to a soluble corticotropin releasing factor receptor related protein, sCRFR2, as well as its effects on CRFR signaling and interaction between CRF family ligand and CRFR receptors, including but not limited to CRFR2, CRFR1 and functional or signaling capable variants thereof.

Abstract: A food product formulation which includes dried hen egg albumen (white), wherein the level of said albumen in said formulation is based on the water absorption or water binding (gelling) capacity of said albumen.

Abstract: The present invention concerns methods and compositions for diagnosing and/or treating vascular diseases including cancer, cardiac diseases, vascular diseases of the eye, and inflammatory diseases. The methods involve measuring the levels of one or multiple miRNAs in patient samples and using the test results to diagnose and/or predict an optimal treatment regimen for the patient. Compositions described in the invention include nucleic acids that function as miRNAs or miRNA inhibitors that can be introduced to a patient to reduce or increase vascularization as needed.

Abstract: Disclosed is a process for coating at least one geometrically defined surface of an optical article's substrate. The process can include: (a) providing a removable carrier made of plastic material and having an internal surface and external surface; (b) providing an optical article comprising a substrate having at least one geometrically defined surface forming a Fresnel lens; (c) depositing a curable coating composition onto either the at least one surface forming a Fresnel lens; (d) moving the carrier and optical article relatively to each other; (e) applying a pressure onto the external surface of the carrier to spread out the curable coating composition to cover said at least one surface forming a Fresnel lens; (f) curing the layer of curable coating composition; (g) withdrawing the removable carrier to recover the substrate of the optical article having at least one Fresnel lens forming surface coated with the cured coating composition.

Abstract: The present invention concerns compositions comprising and methods of identification and use of targeting peptides for placenta or adipose tissue. In certain embodiments, the targeting peptides comprise part or all of SEQ ID NO:5-11, SEQ ID NO:13-22 or SEQ ID NO:144. The peptides may be attached to various therapeutic agents for targeted delivery. Adipose-targeting peptides may be used in methods for weight control, inducing weight loss and treating lipodystrophy syndrome. Adipose-targeting may also be accomplished using other binding moieties selectively targeted to adipose receptors, such as a prohibition receptor protein complex. Placenta-targeting peptides may be used to interfere with pregnancy, induce labor and/or for targeted delivery of therapeutic agents to placenta and/or fetus. In other embodiments, receptors identified by binding to placenta-targeting peptides may be used to screen compounds for potential teratogenicity.

Abstract: Caps and container systems suited to dispensing products like cosmetics. Some of the caps include two portions that can be coupled together and that include a dispensing system that has at least two open positions and at least one closed position.

Abstract: Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N,-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation. This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.

Abstract: An integrated system and method of integrating fluid dispensing technologies (e.g., direct-write (DW)) with rapid prototyping (RP) technologies (e.g., stereolithography (SL)) without part registration comprising: an SL apparatus and a fluid dispensing apparatus further comprising a translation mechanism adapted to translate the fluid dispensing apparatus along the Z-, Y- and Z-axes. The fluid dispensing apparatus comprises: a pressurized fluid container; a valve mechanism adapted to control the flow of fluid from the pressurized fluid container; and a dispensing nozzle adapted to deposit the fluid in a desired location. To aid in calibration, the integrated system includes a laser sensor and a mechanical switch. The method further comprises building a second part layer on top of the fluid deposits and optionally accommodating multi-layered circuitry by incorporating a connector trace.

Abstract: Junction field effect transistors (JFETs) are shown to be a viable replacement for metal oxide semiconductor field effect transistors (MOSFETs) for gate lengths of less than about 40 nm, providing an alternative to the gate leakage problems presented by scaled down MOSFETs. Integrated circuit designs can have complementary JFET (CJFET) logic cells substituted for existing MOSFET-based logic cells to produce revised integrated circuit designs. Integrated circuits can include JFETS where the channel comprises a wide bandgap semiconductor material and the gate comprises a narrow bandgap semiconductor material. Mixtures of JFET and MOSFET transistors can be included on an integrated circuit design.

Abstract: A system and method for high-speed processing of mail pieces is disclosed. The high-speed system includes a conveyor system for transferring mail pieces among two or more mail processing components and a controller for directing the operations of the components. A postage computing device calculates the postage value due for each mail piece. A postage application printer prints postage information, such as Information-Based Indicia (IBI), on the mail pieces that are being moved by the conveyor system. A computer processing system stores information related to the processing of each mail piece and provides the controller with the processing information.

Abstract: The present invention relates to lactoferrin compositions and methods of using the compositions to treat wounds. The compositions can be administered alone or in combination with other standard wound healing therapies.

Abstract: Methods and systems are provided which include configurations for the reassigning unit locations of a classification matrix at which two or more classification regions overlap as non-classification regions. In addition, methods and systems are provided which include configurations for mathematically creating classification regions which may be characterized by values which more accurately correspond to measured values of particles. Other embodiments of methods and systems include configurations for acquiring data corresponding to measurable parameters of a particle and identifying a location within a classification matrix to which at least some of the data corresponds.

Abstract: An apparatus and method of transmitting a Redirect message in a wireless communication system is described. A Redirect message is generated comprising an 8 bit MessageID field, a 16 bit StayAwayDuration field wherein the StayAwayDuration field indicates the units of second for which an access terminal will not make an access attempt at the sector sending this message, an 8 bit NumChannel field wherein the NumChannel indicates the number of channel records included in the message, an 8 bit RedirectReason field wherein the RedirectReason reflect the redirect reason and a Channel field wherein the Channel field indicates the channel that the access terminal should reacquire. The Redirect message is transmitted over a communication link.

Abstract: There are disclosed systems and methods for supporting cargo tanks within the hold of a liquefied gas carrier by establishing a series of spaced-apart pedestals along the longitudinal axis of a tank, said pedestals positioned in conjunction with the ship's structural components. These pedestals are of wood or other suitable thermal insulating and load bearing material fixed to the tank below its circumferential diameter along both the starboard and port tank sides. The pedestals rest on structural longitudinal stringers laying port and starboard in the horizontal plane and fixed and supported by the ship's hull structure. Longitudinal and transverse pedestal movement is controlled by stops attached to the stringers at one or more of the pedestals. The stops contact the pedestals via bearing pads which constrain the pedestal in one direction but permit its movement in another.

Abstract: The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies.

Abstract: The invention concerns a process for making a coated optical lens blank free of visible fining lines which comprises: (ix) providing an optical article having at least one fined but unpolished geometrically defined main face; (x) providing a mold part having an internal and external surface; (xi) depositing on said main face of said optical article or on the internal surface of the mold part a requisit amount of a liquid curable coating composition; (xii) moving relatively to each other the optical article and the mold part to either bring the coating composition into contact with the main face of the optical article or into contact with the internal face of the mold part; (xiii) applying pressure to the mold part to spread the liquid curable coating composition on said main face and form a uniform liquid coating composition layer onto the main face; (xiv) curing the liquid coating composition layer; (xv) withdrawing the mold part; and recovering the free of visible fining lines coated optical article.

Abstract: Methods of determining ACE2 activity in a sample by reacting the sample with ACE2-binding units immobilized on a solid carrier and specific for a part of ACE2 not involved in the catalytic activity of ACE2. The reaction provides a signal that can be correlated with the ACE2 activity. These methods allow for ACE2 activity in complex solutions, such as bodily liquids or culture supernatants, to be quantitatively determined using the endogenous activity of the enzyme to be quantified by converting a signal-providing substrate.

Abstract: A device for generating polarization-entangled photons by means of parametric down-conversion, comprising a waveguide structure formed in a substrate of an optically non-linear material with periodically poled regions, wherein, when in operation, pump photons can be supplied from a pump laser to the waveguide structure, and wherein a separating means for separating the entangled photons for the separate further conduction of signal photons and idler photons, respectively, is arranged to follow the waveguide structure.

Abstract: Disclosed is a light emitting diode (LED) light board. The LED light board includes: a light guide panel (LGP) shaped as a rectangle; an LED module disposed at a lateral side of the LGP and including a plurality of LEDs; a first frame having the LED module embedded therein and coupled to one side of an edge of the LGP; a second frame coupled to the other side of the edge of the LGP perpendicular to both ends of the first frame; and a corner finishing end on which the first frame and the second frame are connected to each other and corners of the first frame and the second frame are finished. The first and second frames include a sidewall formed at one edge of the LGP, an upper wing bent on an end of a sidewall, and a lower wing bent on the other end of the sidewall.

Abstract: A Radio Frequency (RF) component comprising a non-superconducting material, and a superconducting material, wherein the superconducting material is disposed in one or more areas of the RF component such that the areas with superconducting material conduct greater current density than do areas with the non-superconducting material.