Abstract: There is provided a high-spatial-resolution dynamic diagnostic instrument which can provide simultaneous measurements of laser-induced frequency-domain infrared photothermal radiometric and alternating-current (ac) modulated luminescence signals from defects, demineralization, remineralization and caries in teeth intraorally. The emphasis is on the abilities of this instrument to approach important problems such as the detection, diagnosis and ongoing monitoring of carious lesions and or defects on the occlusal pits and fissures, smooth surfaces and interproximal areas between teeth which normally go undetected by x-ray radiographs or visual examination. The instrument is also able to detect early areas of demineralized tooth and or areas of remineralized tooth as well as defects along the margins of restorations. This capability of inspecting a local spot can be extended to a modulated imaging of sub-surface of target tooth by using a multi-array infrared camera.

Abstract: A process for improving optical properties of high-yield pulp (HYP) for producing paper products with superior brightness. Optical brightening agents (OBAs) can effectively improve the optical properties of high-yield pulp (HYP). The present process involves incorporating the OBAs into the alkaline peroxide bleaching process. By combining peroxide bleaching with an optical brightening agent, one can decrease the bleaching cost to reach the same brightness target. Some key advantages of adding OBA to HYP at the pulp mill over the conventional wet-end addition of OBA include: i) the quenching effect on OBA by the wet-end cationic polymers such as PEI is decreased by fixing OBA on HYP fibers; ii) the negative impact of metal ions in the white water system on the OBA performance is minimized when OBA is pre-adsorbed and fixed on HYP fibers; iii) the photo-yellowing (color reversion) of HYP and HYP-containing paper sheets is decreased when more OBA is on HYP fibers to protect them from harmful UV radiation.

Abstract: A unitary steel joist includes a generally vertical web, a generally horizontal bottom flange, a generally horizontal top flange, a bottom wing, a bottom web portion, a top wing and a top web portion. The generally horizontal bottom flange extends outwardly on each side of the web. The bottom flange is made of two pieces of steel. The generally horizontal top flange extends outwardly on each side of the web. The top flange is made of two pieces of steel. The bottom wing extends outwardly from the web. The bottom web portion extends between the bottom flange and bottom wing. The top wing extends outwardly from the web. The top web portion extends between the top flange and the top wing. The unitary steel joist is made from a unitary piece of steel.

Abstract: One aspect of the invention is a foaming component for use in association with a foam dispenser. The foaming component includes an air sparging element, a mixing chamber, and an air chamber. The mixing chamber is on one side of the air sparging element and it defines a portion of the mixing chamber. The air chamber is on the other side of the air sparging element and it defines a portion of the air chamber. The air chamber has an air inlet. The mixing chamber has a liquid inlet and an outlet, and the outlet is down stream of the inlet. The foaming component also forms part of a new foam dispenser. The foaming component and the foam dispenser are for use in the production of foam with a plurality of particles suspended therein. Another aspect of the invention is a dispenser with a foaming component therein.

Abstract: The present invention relates to a method and apparatus for detecting analytes in a medium, and more particularly the present invention relates to an assay based on light diffraction which appears or changes upon the binding of analytes to their specific receptors laid out in patterns on a substrate, which has high sensitivity due to the appropriate choice of such patterns. The present invention is based on the principle that the pattern of recognition elements, which gives rise to the diffraction of the incident light in a diffraction-based assay, can be chosen in such a way so as to facilitate detection, and to enhance the signal to be detected compared to known gratings such as parallel straight lines. In one aspect the substrate itself has a surface topography designed to enhance the diffraction pattern signals. In another aspect the substrate is a diffractive optic element having the analyte-specific receptors affixed to the optic element.

Abstract: A medical robot for use inside a magnetic resonance imager includes a horizontal motion assembly, a vertical motion assembly and a controller. The horizontal motion assembly includes a motion joint, an ultrasonic motor operably connected to the motion joint and an encoder operably connected to the ultrasonic motor. The motor and encoder are positioned proximate to the joint of the horizontal motion assembly. The vertical motion assembly is operably connected to the horizontal motion assembly and it includes a motion joint, an ultrasonic motor operably connected to the motion joint and an encoder operably connected to the ultrasonic motor. The motor and encoder are positioned proximate to the joint of the vertical motion assembly. The controller is operably connected thereto and is adapted to be powered off when the magnetic resonance imager is being used to collect images. A medical instrument assembly is connectable to the medical robot.

Abstract: Embodiments are shown wherein ammonia is used for powering, heating and cooling of various applications including: vehicles (terrestrial, naval, aero-spatial or other engine-driven equipment), residential and commercial buildings, remote generators, refrigerated transport. An ammonia-fuelled internal combustion engine comprising; a thermally insulated fuel tank adapted to store ammonia; a heat exchangers operably connected to the fuel tank, wherein the heat exchanger is adapted to heat the ammonia; a decomposition and separation unit operably connected to the heat exchangers and having a hydrogen conduit and a nitrogen conduit, wherein the decomposition and separation unit is adapted to separate the heated ammonia into hydrogen and nitrogen and stream them into the hydrogen and nitrogen conduits respectively; and an internal combustion engine operably connected to the hydrogen conduit.

Abstract: A medical robot for use inside an MRI includes a horizontal motion assembly, a vertical motion assembly and a controller. The horizontal motion assembly and the vertical assembly each includes a motion joint, an ultrasonic motor operably connected to the motion joint and an encoder operably connected to the ultrasonic motor. The motor and encoder are positioned proximate to the joint of the respective horizontal motion assembly and vertical motion assembly. Each motor has a cross section positioned in one of the axial and sagittal plane of the MRI. A medical instrument assembly is operably connectable to one of the moving joint of the vertical motion assembly. The controller is operably connected to the horizontal motion joint and the vertical motion joint and it is adapted to be powered off when the magnetic resonance imager is being used to collect images.

Abstract: The present invention provides a guidance, navigation, and control method and system for an underground mining vehicle that allow said vehicle to be taught a route by a human operator and then have it automatically drive the route with no human intervention. The method works in three steps: teaching, route profiling, and playback. In the teaching step the vehicle is manually driven by a operator along a route which can consist of an arbitrary sequence of maneuvers including tramming forwards, switching directions, tramming backwards, turning, or pausing movement. During this phase raw data from vehicle-mounted sensors including odometric sensors and rangefinders are logged to a file throughout teaching for later processing. During the (offline) route profiling step, the raw data in the log file are processed into a route profile, and a profile of desired speed as a function of distance along the path.

Abstract: Sensing device and method for detecting presence and concentration of generic target analytes of interest. The device and method are based on detecting changes in effective dielectric induced by the target analytes of interest. Applications of the invention include, but are not restricted to, detecting and characterizing the presence of chemical and/or biological target analytes of interest as well as detecting and characterizing target analytes of interest from a separation apparatus. In one embodiment of the invention, the device comprises at least two electrodes in a rigid architecture such as a solid surface, where the electrodes have sizes and inter-electrode spacings that are on the order of sizes of target analytes of interest to improve sensitivity of the device. Changes in effective dielectric and, therefore, capacitance induced by a presence of the target analytes of interest are measured electronically.

Abstract: A light steel structural member includes a web portion and a pair of flanges. The web portion has a web face. The pair of flange portions each extend generally orthogonally from each end of the web portion. The flange portions each having a plane and the planes are generally parallel each other and each flange has a flange face. At least one of the web face and the flange face has a plurality of embosses formed therein. In another embodiment the light steel structural member further includes a pair of restraining ribs. In a further embodiment the light steel structural member further includes a pair of lips and a pair of multi-cranked stiffeners. A method of making the light steel structural members is shown.

Abstract: The present invention uses spectroscopic tissue volume measurements using non-ionizing radiation to detect pre-disease transformations in the tissue, which increase the risk for this disease in mammals. The method comprises illuminating a volume of selected tissue of a mammal with light having wavelengths covering a pre-selected spectral range, detecting light transmitted through, or reflected from, the volume of selected tissue, and obtaining a spectrum of the detected light. The spectrum of detected light is then represented by one or more basis spectral components, an error term, and an associated scalar coefficient for each of the basis spectral components. The associated scalar coefficient is calculated by minimizing the error term.

Abstract: The present invention provides scanning mechanisms for imaging probes for imaging mammalian tissues and structures using high resolution imaging, including high frequency ultrasound and/or optical coherence tomography. The imaging probes include adjustable rotational drive mechanism for imparting rotational motion to an imaging assembly containing either optical or ultrasound transducers which emit energy into the surrounding area. The imaging assembly includes a scanning mechanism including a movable member configured to deliver the energy beam along a path out of said elongate hollow shaft at a variable angle with respect to said longitudinal axis to give forward and side viewing capability of the imaging assembly. The movable member is mounted in such a way that the variable angle is a function of the angular velocity of the imaging assembly.

Abstract: A method of extracting hormones from a biological sample using digital microfluidic arrays is provided. Biological samples containing hormones are dried on a digital microfluidic array, lysed by a lysing solvent, dried, subsequently dissolved in a polar solvent, and further purified in an extraction step in which droplets are transported through a volume of non-polar solvent. The method disclosed herein provides the distinct advantage of an automated sample preparation method that is capable of extracting hormones from low sample volumes with excellent precision and recovery.

Abstract: A tool for fuelling an unprepared or partially prepared client satellite required for accessing, opening and closing a fuel fill valve on the satellite being serviced, storage and retrieval stations on a tool caddy on which the tools and various fuel fill valve caps are stored. The tool includes interchangeable socket modules, a support frame, a socket module holder mechanism, a socket drive mechanism, a clamping mechanism to secure the tool to a reaction area on the fuel fill valve and oxidizer fill valve, and a valve actuation mechanism. The interchangeable socket modules include a first module for removing and replacing the access valve cap, a second module for coupling the fuel fill line to the fuel tank, a third module for engaging the access valve cap on the oxidizer fill valve, and a fourth module for coupling the oxidizer fill line to the oxidizer tank.

Abstract: The present invention provides an exchangeable, reagent pre-loaded sheets which can be temporarily applied to an electrode array on a digital microfluidic device (DMF). The substrate facilitates virtually un-limited re-use of the DMF devices avoiding cross-contamination on the electrode array itself, as well as enabling rapid exchange of pre-loaded reagents while bridging the world-to-chip interface of DMF devices. The present invention allows for the transformation of DMF into a versatile platform for lab-on-a-chip applications.

Abstract: The present invention provides a method, system and apparatus for robotic refueling of satellites. The system may include a dedicated refueling satellite launched directly from either earth, or alternatively it could be launched from another larger mother spacecraft or space station in which the refueling satellite is ferried into space in the case of the larger space craft or it may be stored on the space station until needed from which it can be launched. The system includes a robotic arm, suitable tools which can be affixed to the end effector of the robotic arm required for accessing, opening and closing the fuel fill valve on the satellite being serviced, storage and retrieval stations on a tool caddy on which the tools and various fuel fill valve caps are stored. The system is under teleoperation by a remotely located operator, for example located on earth, in the mother station or in the space station.

Abstract: The present invention provides assays and methods of compensating for changes in an assay where such changes are due to variations in a perturbing variable. This is achieved by a two-step method, the first step of which involves measurements of the dose-response curve, and thus the individual assay parameters, at different values of the perturbing variable. In the second step, unknown samples are assayed simultaneously with a standard. During this measurement, the value of the perturbing variable is unknown and the dose-response curve is therefore also unknown. The dose-response curves from the first step are used to determine a mathematical relationship between the assay parameters and the assay signal of the standard. Assay parameters that are valid for the unknown value of the perturbing variable can be obtained by substituting the value of the assay signal from the standard into the mathematical relationship and solving for the assay parameters.

Abstract: Assays and methods of compensating for changes in a dose-response curve of an assay due to variations in a perturbing variable by firstly measuring the dose-response curve, the individual assay parameters, at different values of the perturbing variable. Next, unknown samples are assayed simultaneously with a known standard at a chosen analyte concentration with a value of the perturbing variable being unknown and the dose-response curve unknown. The different dose-response curves from the first step are used to determine a mathematical relationship between assay parameters and the assay signal of the known standard. The assay parameters that are valid for the unknown value of the perturbing variable can be obtained by substituting the value of the assay signal from the known standard into the mathematical relationship and solving for the assay parameters.

Abstract: The present invention provides a method and apparatus for dry coating solid dosage forms. The method includes the steps of placing solid dosage forms in a rotatable, electrically grounded housing, and spraying a film forming polymer powder composition into the housing during rotation thereof to form a polymer coating on the solid dosage forms, the polymer powder composition being sprayed using an electrostatic spray gun, and curing the coated solid dosage forms.