Abstract: The use of urocanic acid or another pharmaceutically acceptable agent being able to acidify the cell cytoplasm for the manufacture of a pharmaceutical composition useful for causing inhibition or halting of transformed or non-transformed cell proliferation in a person or an animal, where an effective amount of the agent is administered in an essentially non-dissociated form to the person or animal. The use of the agent as an enhancer for other therapeutically active agents, and a pharmaceutical composition, are also disclosed.

Abstract: A pharmaceutically acceptable agent able to acidify the cell cytoplasm, for the manufacture of a pharmaceutical composition useful for causing immunosuppression in a person or animal, where an effective amount of the agent is administered in an essentially non-dissociated form to the person or animal, and where the agent is admixed with a carrier to adjust the pH of the composition to the pH range 6.1 to 7.0. A pharmaceutical composition is also disclosed.

Abstract: A method and apparatus for pretreating fiber material to be used in manufacturing paper or the like, for example, by precipitating mineral substances to the fibers. During precipitation, fiber material, which is advantageously pretreated in a through-flow mixer operating on the principle of an impact mill, is fed to the precipitation reactor. Gas is led to the precipitation reactor in order to generate a gas space in the reactor. The gas contains a substance, which precipitates the mineral substance such as carbon dioxide (CO2). The fiber material is fed to the gas space of the precipitation reactor as small liquid and solid substance fractions such as drops and/or particles.

Abstract: A method for detecting the presence of a target polynucleotide in a sample, including providing a mixture of the sample and target binding agent and measuring a signal from the mixture, where the target binding agent is capable of assuming a first position where the target binding agent is not bound to the target polynucleotide and a second position where the target binding agent is bound to the target polynucleotide, and the intensity of the signal depends on the proportion of target binding agent in the first and second positions. The method is suitable for detecting a PCR product using a homogeneous detection method.

Abstract: A process for coating the exterior surfaces of a pipeline with a polymer that is cross-linkable under exposure to water, including a) coating the exterior surface of the pipeline with at least one polymer that is cross-linkable under exposure to water, where the employed cross-linkable polymer includes alkoxy silane grafted HDPE; and b) cross-linking of the cross-linkable polymer by exposure to water at elevated temperatures so as to form a cross-linked polymer layer having a degree of cross-linking of from 30% to 80% is reached.

Abstract: A homogenous bioassay including i) a first group containing a short lifetime fluorescent acceptor, and ii) a second group containing a quencher, with the first and second groups linked by at least a first linkage. The bioassay measures the acceptor's fluorescence increase resulting from cleavage of the first linkage and also includes iii) a third group containing a donor for energy transfer to the acceptor, where the donor is an up-conversion fluorescent compound, a long-lifetime fluorescent compound or an electrogenerated luminescent compound. A conformational or terminal epitope is created on the first group through linkage cleavage, and the third group includes a binder with affinity for this epitope. The acceptor's fluorescence is caused by exciting the donor. Also disclosed are bioassay kits for this method.

Abstract: A method and apparatus for producing a calcium carbonate product formed of small <100 ?m sized separate calcium carbonate particles. Calcium hydroxide is fed through a disintegration and spraying apparatus (14), operating on the principle of a pin mill, into a gas which contains carbon dioxide for precipitating calcium carbonate particles and which is inside a precipitation reactor (10). The temperature in the precipitation reactor is maintained at <65° C.

Abstract: The invention concerns a method for manufacturing a radio frequency identification device (RFID), the device featuring an antenna and a chip (12) connected to the antenna, the method including the following steps: printing an antenna (12) having contacts (17 and 19) on a support (20) made of paper or synthetic paper, placing adhesive dielectric material between the contacts of the antenna, positioning an integrated circuit module (10) on the support, the module featuring groups of contacts (17, 18) and the chip (12) connected to groups of contacts inside an encapsulation (14) of the module, so that the groups of contacts of the module are opposite the contacts of the antenna, placing a thermoplastic layer (22) and a paper or synthetic paper layer (24) on the support, the two layers (22 and 24) being provided with a recess (21, 23) at the location of encapsulation (14) of the module (10), laminating together the three layers, the antenna support layer (20), the thermoplastic layer (22) and the paper or synt

Abstract: A method and kit for draining a flexible container holding a product having a viscosity of between 10 Pa·s and 200 000 Pa·s. The method includes using a flexible container (3); optionally, moving the container (3) to be drained to a drainage site; ensuring the viscous product (2) can flow from container (3) through at least one outlet (9); exerting a pressure on at least one defined area of container (3) using a pressurizing device which preferably includes at least one pressure member (5) and/or a pressure fluid to maintain container (3) in an inflated or partially-inflated state; and removing the pressure once the container has been drained. The drainage kit includes the viscous product (silicon mastic), a flexible container (3) and a draining device including at least one pressure member and/or pressure fluid.

Abstract: The invention relates to a method of controlling the solubility of granular material by treating a precipitate comprising iron(II)sulphate monohydrate originating from titanium dioxide production, in which method the reaction temperature is allowed to increase at the most to a temperature of 120° C., to a plant for treating a precipitate comprising iron(II)sulphate monohydrate, to a product and its uses. A typical method according to the invention comprises the steps of mixing water to the reaction mixture in the said mixing apparatus, and keeping the amount of neutralizing agent sufficient to give a pH value from 1.5 to 4, preferably from 1.5 to 3, to the end product in order to obtain a granular material having a high soluble iron(II) content or keeping the amount of neutralizing agent sufficient to give a pH value ?9 to the end product in order to obtain a granular material having a low solubility.

Abstract: The present invention relates to the use of tocopherol as a co-catalyst in the ring opening polymerisation of cyclic siloxanes. The present invention further relates to a method for manufacturing hydrophilic polysiloxanes, wherein a hydrido-containing cyclic siloxane is reacted with a hydrophilic molecule comprising a carbon-carbon double bond, having the general formula (I) H2C?CH—(CHR)n—O—(CHR1CR2R3)mR4 or (II) H2C?CH—(CHR)n—R5, wherein n is an integer from 0 to 4, m is an integer from 0 to 5, R, R1, R2, R3 and R4 are each independently hydrogen or a C1 to C6 alkyl, R5 is a saturated cyclic hydrocarbon containing carbonyl group, in the presence of a first catalyst to obtain a monomer, and polymerising said monomer in the presence of a second catalyst and tocopherol as a co-catalyst.

Abstract: A method for manufacturing an identity booklet cover provided with a radio frequency identification device having an antenna and a chip (12) connected to the antenna, the method including the following steps: producing an antenna (12) having contacts (13 and 14) on a support (10), creating a recess (20) between the contacts (13 and 14), placing adhesive dielectric material (25, 26) near the contacts of the antenna, positioning an integrated circuit module (19) on the support so that the groups of contacts of the module are opposite the contacts of the antenna and the encapsulation of the module is in the recess (20), placing on the face of the support featuring the antenna at least one layer of thermo-adhesive film (40, 50, 60), placing a cover layer (70) on the layer (or) layer(s) (40 or 50 and 60) of thermo-adhesive film, laminating all the layers.

Abstract: A method and apparatus for producing a calcium carbonate product formed of small <100 ?m sized separate calcium carbonate particles. Calcium hydroxide is fed through a disintegration and spraying apparatus (14), operating on the principle of a pin mill, into a gas which contains carbon dioxide for precipitating calcium carbonate particles and which is inside a precipitation reactor (10). The temperature in the precipitation reactor is maintained at <65° C.

Abstract: A vibrating plate apparatus including a vibrating plate on which a user rests, a vibration motor member connected to the vibrating plate, several air cushions provided under the vibrating plate for dampening vibration, and an air tank in communication with each of the air cushions. The tank establishes the air pressure in at least one of the air cushions at a predetermined value independently from the user's weight. The motor member includes two motors rotating in opposite directions, each of the two motors including a set of flyweights driven by the two motors and having a center of gravity offset relative to the axis, the two sets having the same mass, being symmetrical to each other and including at least one moveable flyweight that can assume at least one position to vary the vibrating plate's vibration amplitude.

Abstract: A method for connecting an electronic chip (10) to contacts (47and 48) of an electric circuit, the chip having two conductive plates (31and 32) located on the last layer of the chip and at least one electromagnetic shielding layer, at least one of the plates (31or 32) being entirely covered with an electrical insulating layer (34). The method includes placing an adhesive dielectric material (40) on the circuit between the contacts (47, 48), to fix the electronic chip (10) relative to the circuit, positioning electronic chip (10) on the circuit so that conductive plates (31et 32) are opposite the contacts (47and 48), so as to create between the chip and the electric circuit at least one capacitive link made up of the conductive plate (31or 32), the electrically insulating layer and the contact (47or 48).

Abstract: The use of i) finely divided knotwood, or ii) an extract, obtained by extracting knotwood with a polar solvent and recovering the extract, as an antioxidative agent. A fraction of the extract may also be used as an antioxidative agent.

Abstract: A reagent container having an inner surface upon which at least two reagents are dried, with the first reagent dried on a first area separate from a second area where the second reagent is dried. The first and second reagents are a nucleic acid polymerase and its substrate. A method is disclosed which includes dispensing at least the first and second reagents onto separate areas of the inner surface of the reagent container, and removing excess water from the reagents. The reagent container can be used in a polymerase chain reaction (PCR) assay, an assay that utilizes a reverse transcriptase, a reverse transcriptase polymerase chain reaction, an immuno-PCR assay, a nucleic acid sequence based assay, a proximity ligation assay, a ligase chain reaction assay, a rolling circle amplification assay, and a strand displacement amplification assay.

Abstract: Cradle for a passenger cabin of an aircraft, suitable for a child of less than 2 years old capable of sitting upright, comprising a rigid and formable structure formed by a rectangular frame and two uprights, designed to be fixed to one wall of the cabin, and a cover with mattress attached to the rectangular frame. The cover comprises in one of its longitudinal sides two windows separated by a strip of fabric and closed by a retractable tulle flap in such a way that the child can sit upright in the cradle with his or her legs passing out of the cradle through the windows and on either side of the fabric strip when the flap has been retracted.

Abstract: Implant articles with improved osseointegrating properties, osteogenic implant materials, and process of inducing differentiation of mesenchymal stem cells, proliferation of osteoblast and attachment of cells to implant surface, comprising the step of impregnating the surface with a solution containing osteoactive bone sialoprotein, recombinant human bone sialoprotein, recombinant His-Myc-Ek-BSP or substantive fragments thereof that have not been in contact with serum containing complement factor H or any other BSP processing material.

Abstract: An aqueous polyorganosiloxane (POS) emulsion which can easily be deposited on/applied to a fibrous substrate at high speed and at limited deposition rates, for example less than 40 g/m2. The emulsion contains (A) a POS with ?Si-vinyl units, (B) a POS with ?SiH units, (C) an adhesion promoter, (D) a catalyst, (E) at least one surfactant, (F) optionally a POS resin with ?Si-vinyl units, (G) optionally a crosslinking inhibitor, (H) optionally a pH fixing agent, (I) optionally a formulating additive, (J) optionally a filler, and (K) water. Adhesion promoter (C) is selected from protective hydrocolloids, hydroxylated silanes and/or POS carrying at least one hydroxyl group and at least one salified amino group per molecule, and mixtures thereof, and is present in the range from 0.005 to 10% by weight, based on the silicone phase. Also disclosed is the corresponding coating process and the coated substrate.