Abstract: According to one aspect of the invention, there is provided a compound of formula (I) and solvates thereof. There are also provided compositions containing the compound, processes for preparing it, and its use in therapy.
Type:
Grant
Filed:
August 3, 2001
Date of Patent:
September 5, 2006
Assignee:
Glaxo Group Limited
Inventors:
Keith Biggadike, Steven John Coote, Rosalyn Kay Nice
Abstract: There is provided a sample container comprising a retainer for retaining a sample; and a radiofrequency identifier comprising an antenna for transmitting or receiving radiofrequency energy; an integrated circuit chip connecting with said antenna; and a carrier for the radiofrequency identifier; wherein the radiofrequency identifier is on the carrier and the carrier connects to the retainer.
Type:
Grant
Filed:
May 2, 2001
Date of Patent:
August 15, 2006
Assignee:
Glaxo Group Limited
Inventors:
Jeffrey Douglas Veitch, Robert Anthony Biddlecombe
Abstract: A medicament cartridge for use in an inhalation device comprising a carrier having a plurality of medicament retainers in a spiral path arrangement. Typically, the carrier is substantially planar. In one embodiment the carrier comprises an elongate carrier storable in a flat spiral configuration and extendable as a helix. There is also provided an inhalation device comprising a housing having an air inlet, an air outlet, an airway therebetween and a medicament carrier having a plurality of medicament retainers in a spiral path arrangement. A mover is provided for moving the medicament carrier relative to the housing so as to bring successive medicament retainers individually into communication with the airway.
Abstract: A method of controlling the functioning of a portable medicament dispenser, said method comprising: (a) providing a memory for storing one or more parameters relating to the functioning of said dispenser; (b) storing authentication data for authenticating data for controlling a function of said dispenser; (c) receiving control data for said dispenser; (d) performing authentication of the control data using said stored authentication data; (e) in dependence on a result of the authentication, activating one or more parameters in said memory to control functioning of said dispenser in accordance with said control data.
Type:
Grant
Filed:
April 2, 2002
Date of Patent:
July 4, 2006
Assignee:
Glaxo Group Limited
Inventors:
Stanley George Bonney, Anthony Patrick Jones, Duncan Robertson
Abstract: There is provided a method for tracking environmental exposure of an object comprising selecting the object; associating a radiofrequency identifier with the object, the radiofrequency identifier comprising an antenna for transmitting or receiving radiofrequency energy; and an integrated circuit chip connecting with said antenna, said chip having a memory; exposing the object to an environmental condition; measuring environmental condition as an environmental parameter with a sensor physically separate from the radiofrequency identifier; and writing the environmental parameter to the memory of the chip by transmitting radiofrequency energy thereto.
Abstract: There is provided a system for the delivery of medicament comprising a medicament container; a dispensing mechanism for dispensing medicament from the medicament container; an electronic data management system; and a communicator for wireless communication with a network computer system to enable communication of data between the network computer system and the electronic data management system. The electronic data management system comprises a memory for storage of data; a microprocessor for performing operations on the data; and a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data.
Type:
Grant
Filed:
September 22, 2000
Date of Patent:
October 25, 2005
Assignee:
SmithKline Beecham Corporation
Inventors:
Gregor John McLennan Anderson, Stanley George Bonney, Anthony Patrick Jones, Duncan Robertson
Abstract: There is provided a method of forming a blister pack comprising contacting a base sheet having a blister pocket therein with a cover sheet and applying laser energy to form a join between said cover sheet and said blister pocket of said base sheet. The blister pack is preferably in the form of an elongate strip. The blister pack is suitable for the containment of a range of different products, particularly medicaments.
Type:
Grant
Filed:
April 19, 2000
Date of Patent:
September 20, 2005
Assignee:
SmithKline Beecham Corporation
Inventors:
Stanley George Bonney, James William Godfrey
Abstract: There is provided a carrier comprising a sheet (10) having a first portion and a second portion; a retainer (20) in said first portion for containment of product; a fold in said second portion such that the second portion is foldable towards said retainer to form a cover therefor; and a join between said cover and the retainer. The carrier is suitable for the containment of a range of different products, particularly medicaments.
Type:
Grant
Filed:
April 19, 2000
Date of Patent:
August 16, 2005
Assignee:
SmithKline Beecham Corporation
Inventors:
Stanley George Bonney, Michael Birsha Davies, James William Godfrey, Sylvia Maria Haglund, Paul Kenneth Rand
Abstract: A medicament pack comprising a first body portion having a pocket and a second body portion having an airpath. The pocket is sealed to a foil cover which connects to the second body portion. The second body portion is movable over the first body portion to break the seal and bring the pocket into communication with the airpath.
Type:
Grant
Filed:
October 11, 2000
Date of Patent:
July 12, 2005
Assignee:
SmithKline Beecham Corporation
Inventors:
Gregor John McLennan Anderson, Duncan Robertson
Abstract: There is provided a method of transferring a defined quantity of powder comprising compacting a target area of powder; dipping a tube into the compacted target area of powder to fill the tube with a defined volume of powder; and transferring the defined volume of powder from the tube.
Abstract: There is provided a medicament dispenser for dispensing medicament comprising: a body; a holder, shaped to fit within the body and movable relative to the body; and receivable by said holder, a cassette containing a medicament carrier, wherein movement of the holder relative to the body results in movement of the cassette between a first position and a second position such that the cassette is reversibly removable from the holder when the cassette is in the second position.
Type:
Grant
Filed:
October 19, 2001
Date of Patent:
April 19, 2005
Assignee:
Glaxo Group Limited
Inventors:
Gregor John McLennan Anderson, Philip William Farr, Paul Kenneth Rand, Stephen James Harvey
Abstract: According to one aspect of the invention, there is provided a pharmaceutical formulation for administration by inhalation comprising a compound of formula (I), wherein R1 represents C1-6 alkyl or C1-6 haloalkyl; R2 represents —C(?O)-aryl or —C(?O)-heteroaryl; R3 represents hydrogen, methyl (which may be in either the ? or ? configuration) or methylene; R4 and R5 are the same or different and each represents hydrogen or halogen; and represents a single or a double bond; and salts and solvates thereof together with a long-acting ?2-adrenoreceptor agonist which formulation has a therapeutically useful effect in the treatment of COPD over a period of 24 hours or more.
Type:
Grant
Filed:
October 28, 2002
Date of Patent:
April 12, 2005
Assignee:
Glaxo Group Limited
Inventors:
Keith Biggadike, Paul Spencer Jones, Jeremy John Payne
Abstract: There is provided a crystalline chemical composition comprising a compound of formula (I) in which the crystal lattice is stabilized by the presence of a guest molecule, characterized in the crystalline composition is of space group P212121 having unit cell dimensions of about 7.6±0.6 ?, 12.7±0.7 ?, and 33±3 ? when determined at 120 K.
Type:
Grant
Filed:
July 22, 2002
Date of Patent:
February 22, 2005
Assignee:
Smithkline Beecham Corporation
Inventors:
Keith Biggadike, Olga Chetina, Steven John Coote, Andrew Craig, Victor Jacewicz, Michael J. Millan, John F. Seager, Andrew L. Theophilus
Abstract: There is provided a method for automatically tracking compliance in a manufacturing process involving successive manufacturing operations comprising selecting an object; associating an identifier with said object, said identifier comprising a memory; performing a first manufacturing operation relating to the object; following the successful completion of said first manufacturing operation, writing an associated compliance data item to the memory; performing one or more further manufacturing operations relating to the object; and following the successful completion of each said further manufacturing operation or any package thereof, writing an associated compliance data item to the memory.
Type:
Grant
Filed:
February 21, 2001
Date of Patent:
January 4, 2005
Assignee:
Smithkline Beecham Corporation
Inventors:
James William Godfrey, Stanley George Bonney
Abstract: There is provided according to the invention a pharmaceutical formulation comprising an aqueous carrier liquid having dissolved therein (a) an ester of fluticasone or a solvate thereof as medicament and (b) a solubilising agent for assisting the solubilisation of the medicament in the aqueous carrier liquid.
Type:
Grant
Filed:
February 4, 2002
Date of Patent:
September 7, 2004
Assignee:
SmithKline Beecham Corporation
Inventors:
Keith Biggadike, Amyn P. Sayani, Ian Buxton, Kenton Reed