Patents Represented by Attorney John Dana Hubbard
  • Patent number: 6021925
    Abstract: An apparatus is provided for delivering precise volumes of a sample liquid. A piston is moved linearly into a first chamber containing an incompressible hydraulic liquid. The chamber includes one wall formed of a flexible diaphragm. The diaphragm separates the first chamber from a second chamber containing a sample liquid. The degree of expansion of the diaphragm and dispensing of the sample liquid from the second chamber are dependent upon the position of the piston within the first chamber.
    Type: Grant
    Filed: April 21, 1998
    Date of Patent: February 8, 2000
    Assignee: Millipore Corporation
    Inventors: Iraj Gashgaee, Graham Eacock, George L. Gonnella
  • Patent number: 6000558
    Abstract: A filter element for filtering a particle-containing paint composition or a particle loading slurry composition which is a precursor to a particle-containing paint composition is provided. The filtration element comprises at least one filtration layer formed from woven polymer fibers and having substantially uniform pores and two spacer layers. The spacer layers have raised projections to create a space between adjacent spacer layers having contacting projections. The filtration element has a pleated or spirally wound configuration.
    Type: Grant
    Filed: October 9, 1997
    Date of Patent: December 14, 1999
    Assignee: Millipore Corporation
    Inventors: Stephen Proulx, Michael L. Heise
  • Patent number: 5984267
    Abstract: A device for isolating and containing gas reactive materials includes a novel valve arrangement that is actuatable in conjunction with the movement of a pre-loaded metal diaphragm. The pre-loaded diaphragm force is sufficient to form a fluid tight seal when the device is disconnected from a gas supply line thereby sealing the interior of the device from the surrounding environment.
    Type: Grant
    Filed: August 29, 1997
    Date of Patent: November 16, 1999
    Assignee: Millipore Corporation
    Inventor: Roger R. Coutu
  • Patent number: 5935441
    Abstract: Ultrapure water containing less than 10 ppt total ions, other than hydrogen ion and hydroxide ion is produced by passing deionized water through a system comprising an ultrafiltration step, an oxidizing step where water is exposed to ultraviolet light and ion exchange step. The treated water is recirculated through the oxidizing step and the ion exchange step. Product water from the system can be recovered on a continuous basis so long as the ratio of volume of water circulated within the system to volume of water drawn from the system is at least 10 and preferably at least 20.
    Type: Grant
    Filed: September 5, 1996
    Date of Patent: August 10, 1999
    Assignee: Millipore Corporation
    Inventors: Gary A. O'Neill, Kitty K. Siu, Jeffrey P. Denoncourt
  • Patent number: 5928792
    Abstract: A process is provided for producing a porous membrane product comprising a porous membrane having its surface completely modified with a perfluorocarbon copolymer composition. The porous membrane substrate is contacted with a solution containing a perfluorocarbon copolymer composition to bind the composition onto the substrate surface. The substrate is subjected to a mechanical force to remove excess perfluorocarbon copolymer composition and then is heat treated.
    Type: Grant
    Filed: May 10, 1997
    Date of Patent: July 27, 1999
    Assignee: Millipore Corporation
    Inventor: Wilson Moya
  • Patent number: 5922200
    Abstract: A filtration apparatus for deadend filtration is provided which is formed from multilayer presealed elements and monolayer elements that are insert molded together. The device is provided with a feed port, and a filtrate port. The sealing configuration of the presealed elements and the seal provided by the insert molding step effect a seal configuration that causes a feed liquid to be filtered to form a filtrate such that the filtrate is not mixed with the feed.
    Type: Grant
    Filed: April 22, 1997
    Date of Patent: July 13, 1999
    Assignee: Millipore Corporation
    Inventors: Steven R. Pearl, Wayne S. Merrill, Cristopher J. Petersen
  • Patent number: 5885456
    Abstract: A porous membrane, such as a microporous or ultrafiltration membrane, is formed from a solution of a polysulfone and a free radical polymerizable monomer exposed to ultraviolet light to form a blend of the polysulfone and copolymers of polysulfone activation products and polymerized monomer having polymer segments covalently bonded to each other. The solution is separated into two phases including a porous solid phase comprising the membrane.
    Type: Grant
    Filed: August 9, 1996
    Date of Patent: March 23, 1999
    Assignee: Millipore Corporation
    Inventors: John Charkoudian, Anthony E. Allegrezza, Jr.
  • Patent number: 5883150
    Abstract: A polysulfone composition is formed from a solution of a polysulfone and a free radical polymerizable monomer exposed to ultraviolet light to form a blend of the polysulfone and copolymers of activated polysulfone and polymerized monomer having polymer segments covalently bonded to each other. The blend is separated from solvent of the solution to form a solid comprising the blend throughout its bulk matrix.
    Type: Grant
    Filed: August 9, 1996
    Date of Patent: March 16, 1999
    Assignee: Millipore Corporation
    Inventor: John Charkoudian
  • Patent number: 5873967
    Abstract: A vacuum filter device is disclosed which includes a filter body which is adapted to receive in fluid-tight, sealed relationship a pair of closed containers for solutions to be filtered by a membrane filter positioned within the filter body. A vacuum port in the filter body communicates with the downstream side of the membrane and a venting passageway also located in the filter body communicates with the closed sample container to serve as a vent to atmospheric pressure. The venting passageway is made of an air permeable hydrophobic filter or preferably a small enough opening to prevent the sample solutions from leaking out of the device during normal use.
    Type: Grant
    Filed: March 24, 1997
    Date of Patent: February 23, 1999
    Assignee: Millipore Corporation
    Inventors: Phillip Clark, Brian D. Foley, Aldo M. Pitt
  • Patent number: 5862856
    Abstract: A heat exchange apparatus is provided which is formed from at least one multilayer presealed element and at least one monolayer element that are insert molded together. The heat exchange apparatus is provided with an inlet and an outlet for a process fluid and at least one inlet and at least one outlet for a heat exchange fluid. The sealing configuration of the presealed elements and the seal provided by the insert molding effect a seal configuration that causes heat to be transferred between the process fluid and the heat exchange fluid while preventing mass transfer between the two fluids.
    Type: Grant
    Filed: September 19, 1997
    Date of Patent: January 26, 1999
    Assignee: Millipore Corporation
    Inventors: Steven R. Pearl, Charles D. Christy
  • Patent number: 5851390
    Abstract: A filtration unit containing a filtering membrane, a cover upstream of the membrane, and a base downstream of the membrane, and joined together, characterized in that the filtering membrane has an elliptical shape. This elliptical shape facilitates the use for filtration and allows the unit to be reused without the formation of an air lock when the filtering membrane is partially hydrophobic.
    Type: Grant
    Filed: December 11, 1996
    Date of Patent: December 22, 1998
    Assignee: Millipore S.A.
    Inventor: Jean Lemonnier
  • Patent number: 5844125
    Abstract: A device for measuring moisture concentration in a gas is provided which includes a sensing device capable of producing physical response to an energy input and having at least one surface coated with a metal hydroxide capable of adsorbing moisture. The metal hydroxide is derived from a metal coating on the sensing device.
    Type: Grant
    Filed: October 1, 1997
    Date of Patent: December 1, 1998
    Assignee: Millipore Corporation
    Inventor: John E. Pillion
  • Patent number: 5824217
    Abstract: A filtration apparatus is provided which is formed from multilayer presealed elements and monolayer elements that are insert molded together. The device is provided with a feed port, a filtrate port and, optionally, a retentate port. The sealing configuration of the presealed elements and the seal provided by the insert molding step effect a seal configuration that causes a feed liquid to be filtered to form a filtrate such that the filtrate is not mixed with either the feed or a retentate.
    Type: Grant
    Filed: March 27, 1996
    Date of Patent: October 20, 1998
    Assignee: Millipore Corporation
    Inventors: Steven R. Pearl, Wayne S. Merrill, Christopher J. Petersen
  • Patent number: 5814372
    Abstract: A composite porous membrane is provided which comprises a porous membrane substrate having an average pore size between 0.01 and 10 microns formed of a first polymer which is coated over its entire surface with a crosslinked second polymer. The second polymer is dissolved in a solvent with a free radical polymerization initiator in the absence of a crosslinking agent. The second polymer is crosslinked in situ and rendered insoluble by mild heating and/or exposure to ultraviolet light.
    Type: Grant
    Filed: September 26, 1996
    Date of Patent: September 29, 1998
    Assignee: Millipore Corporation
    Inventor: Wilson Moya
  • Patent number: 5798049
    Abstract: A filter element for filtering a particle-containing paint composition or a particle loading slurry composition which is a precursor to a particle-containing paint composition is provided. The filtration element comprises at least one filtration layer formed from woven polymer fibers and having substantially uniform pores and two spacer layers. The spacer layers have raised projections to create a space between adjacent spacer layers having contacting projections. The filtration element has a pleated or spirally wound configuration.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: August 25, 1998
    Assignee: Millipore Corporation
    Inventors: Stephen Proulx, Paul J. Cook, Michael L. Heise
  • Patent number: 5786528
    Abstract: An improved water flow test for determining the integrity and/or pore size distribution of a porous filter is disclosed. The improvement involves the ability to determine and take into account the changes in filter structure due to filter compaction or creep resulting from compressive forces when pressure is applied to the surfaces of the filter. By proper characterization of the filter under test, the initial system volume and the volume change associated with pressurizing the filter can be accurately determined at all points in time during a test cycle. As a result, composite flowrate changes (i.e. the flow due to filter compaction/creep plus the flow due to liquid intrusion) can be evaluated to distinguish between various flow components to accurately determine the pore size of the filter being tested or a filter defect.
    Type: Grant
    Filed: September 10, 1996
    Date of Patent: July 28, 1998
    Assignee: Millipore Corporation
    Inventors: Anthony J. Dileo, Richard W. Gray
  • Patent number: 5766868
    Abstract: An improved method of determining a viable microbial cell count in a sample solution with an enhanced detection sensitivity is provided, comprising filtering the sample solution through a filtration membrane having hydrophobic properties to entrap microbes within hydrophobic barriers; applying thereto a fine spray of ATP releasing reagent to extract a luminescent ingredient from the microbes; applying thereto another fine spray of liquid luminescence-inducing reagent to allow the released luminescent ingredient to emit luminescence; and measuring the level of the luminescence, using a competent means for measuring the luminescence level. The microbes and the two types of reagents are locally concentrated due to the hydrophobic properties of the membrane and thus the sensitivity is greatly enhanced, permitting instant counting in the case of large microbes, and decreased culture time for smaller bacterial microbes.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: June 16, 1998
    Assignee: Millipore Corporation
    Inventor: Susumu Seto
  • Patent number: 5762789
    Abstract: A membrane filtration module is disclosed for use in fluid processing systems in which all active connections between the module and the fluid processing system are located only on one end of the module. A central flow conduit within the module directs all of the flow of liquid from one of the connections to the opposite end. In this manner, dead volume is essentially eliminated as the flow pattern causes the liquid to sweep all the volume within the module while still providing for easy installation and replacement by virtue of having all of the active connections on only one end.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: June 9, 1998
    Assignee: Millipore Corporation
    Inventors: Gaston de los Reyes, J. Karl Niermeyer
  • Patent number: 5738335
    Abstract: A device for isolating and containing gas reactive materials includes a novel valve arrangement that is actuatable in conjunction with the movement of a pre-loaded metal diaphragm. The valve is situated in a housing having an inlet and an outlet fitting, a seat for the diaphragm and a metal tube in contact with the diaphragm to provide fluid communication between the housing and the gas supply to that the pre-loaded diaphragm is opened upon the connection of the gas supply to allow gas flow to the gas reactive material disposed within the housing. The pre-loaded diaphragm force is sufficient to form a fluid tight seal when the device is disconnected from a gas supply line therby sealing the interior of the device from the surrounding enviroment.
    Type: Grant
    Filed: September 10, 1996
    Date of Patent: April 14, 1998
    Assignee: Millipore Corporation
    Inventor: Roger R. Coutu
  • Patent number: 5736044
    Abstract: A filter element for filtering a particle-containing paint composition or a particle loading slurry composition which is a precursor to a particle-containing paint composition is provided. The filtration element comprises at least one filtration layer formed from woven polymer fibers and having substantially uniform pores and two spacer layers. The spacer layers have raised projections to create a space between adjacent spacer layers having contacting projections. The filtration element has a pleated or spirally wound configuration.
    Type: Grant
    Filed: January 15, 1997
    Date of Patent: April 7, 1998
    Inventors: Stephen Proulx, Paul J. Cook, Michael L. Heise