Abstract: The present invention relates to stable water-containing cosmetic or pharmaceutical compositions which comprise a biologically active agent and an enzyme-based oxygen-scavenging antioxidant system. The composition preferably comprises an antioxidant system comprising effective amounts of an oxidase, a substrate for the oxidase, and a peroxidase, and at least one species oxidizable by hydrogen peroxide, such as iodide and/or thiocyanate anions.
Type:
Grant
Filed:
September 30, 1997
Date of Patent:
October 26, 1999
Assignee:
E-L Management Corp.
Inventors:
E. Althea Knight, Akshay Talati, Jules Zecchino
Abstract: The invention relates to waterproof or water resistant compositions for application to the lashes comprising a styrene-ethylene-propylene copolymer as gellant, a film forming agent, and a volatile oil.
Type:
Grant
Filed:
October 31, 1997
Date of Patent:
September 28, 1999
Assignee:
E-L Management Corp
Inventors:
Richard A. Konik, Rachel J. Painter, George J. Stepniewski
Abstract: The invention relates to topical cosmetic or pharmaceutical compositions comprising an anti-stinging effective amount of an amino acid selected from the group consisting of an amino butyric acid, glutamine, glycine, and derivatives thereof, or mixtures thereof, as well as methods of reducing or preventing stinging using such compositions.
Type:
Grant
Filed:
September 19, 1997
Date of Patent:
September 28, 1999
Assignee:
E-L Management Corp.
Inventors:
Neelam Muizzuddin, Kenneth D. Marenus, Glen Rein, Mary Steidl Matsui
Abstract: The present invention relates to a self-tanning composition comprising an effective amount of DHA in combination with an effective amount of a long-chain alpha hydroxy acid(AHA). In a preferred embodiment, the AHA is .alpha.-hydroxy lauric acid.
Type:
Grant
Filed:
May 21, 1997
Date of Patent:
August 24, 1999
Assignee:
E-L Management Corp.
Inventors:
Peter J. Lentini, Paul Tchinnis, Neelam Muizzuddin
Abstract: Disclosed are skin smoothing compositions containing hydroxyacids or hydroxyacid derivatives, a polymeric film-forming agent, a physical exfoliant, and a pharmaceutically acceptable carrier. Also disclosed are methods for using the skin smoothing compositions to improve the smoothness of human skin.
Type:
Grant
Filed:
November 18, 1997
Date of Patent:
August 17, 1999
Assignee:
E-L Management Corp
Inventors:
Michelle Matathia Jacobs, Peter J. Lentini
Abstract: Hair upon the scalp or eyelashes are treated with hair coloring or mascara compositions in hair or eyelash coloring methods. The hair is typically colored with a mascara brush to achieve streaking and a non-homogenous coloring of the hair upon the scalp or the eyelash. A copaiba resin and a metal containing pigment are combined to obtain the hair coloring product. The resultant product is applied to the hair upon the scalp or the eyelash to effect coloring of the hair upon the scalp or the eyelash.
Type:
Grant
Filed:
April 28, 1998
Date of Patent:
March 30, 1999
Assignee:
Aveda Corporation
Inventors:
Stanley Ray Fogg, Timothy Roland Kapsner
Abstract: The present invention relates to novel purified gibbon ape leukemia receptor proteins and purified DNA sequences encoding these receptor proteins.
Abstract: The present invention relates to a liquid dual phase cosmetic or pharmaceutical composition comprising an oil phase and an aqueous phase, the composition containing as a demixing agent a quaternary nitrogen-containing ether substituted alkoxylated alkyl glucoside. The compositions of the invention are particularly useful as makeup removers.
Type:
Grant
Filed:
December 11, 1996
Date of Patent:
February 16, 1999
Assignee:
E-L Management Corp.
Inventors:
Adrienne Nagy, Linda Najdek, Elena M. Ciriello, Henry Maso, Ralph Vitale
Abstract: The present invention relates to topical compositions useful in enhancing lipid synthesis in skin comprising an effective amount of cafestol, in combination with a pharmaceutically or cosmetically acceptable carrier. Such compositions are useful in treatment or prevention of dry skin and conditions in which the skin's lipid barrier is defective or damaged.
Abstract: Water-based makeup compositions and methods for their preparation are disclosed. The compositions comprise a water-dispersible pigment having a nonionic coating, a lipid vesicle comprising one or more lipid components, and a cosmetically or pharmaceutically acceptable aqueous carrier, and possess unusual stability at low pH. A method for the preparation of such water-based makeup compositions is disclosed as well.
Type:
Grant
Filed:
June 10, 1996
Date of Patent:
December 8, 1998
Assignee:
E-L Management Corp.
Inventors:
Kathleen DaCunha, Linda McKenna, David Chant, Deborah Jennings
Abstract: The present invention relates to nonchemical sunscreen composition comprising as its active components, in synergistically effective amounts, a plant extract containing at least about 50% by weight of proanthocyanidins, .gamma.-oryzanol, ferulic acid and/or an ester thereof, titanium dioxide and optionally, Scutellaria extract.
Abstract: The present invention relates to a clear cosmetic stick composition comprising (a) from about 3-15% of a soap gelling agent; (b) from about 10-90% of at least one polyhydric alcohol solvent; and (c) from about 0.5-10% of a combination of the clarifying agents pentadoxynol 200 and ethoxylated jojoba esters. The composition is useful, for example, as the base for a deodorant stick.
Type:
Grant
Filed:
January 24, 1997
Date of Patent:
September 29, 1998
Assignee:
E-L Management Corp
Inventors:
Adrienne Nagy, Joanne Leaver, Steven Messin, Donna Meningall
Abstract: The present invention relates to cosmetic or pharmaceutical compositions containing a preservative-effective amount of hinokitiol-containing microcapsules, the microcapsules comprising a matrix containing collagen and a glycosaminoglycan.
Type:
Grant
Filed:
June 12, 1996
Date of Patent:
September 22, 1998
Assignee:
E-L Management Corp.
Inventors:
Althea Knight, Julius Zecchino, Steven Schnittger
Abstract: The present invention relates to a protection-effective amount of UV-damaged RNA fragments, in combination with a cosmetically or pharmaceutically acceptable carrier. The compositions are useful in the prevention of skin damage to UV radiation and in preventing photoaging.
Abstract: A method for detecting a tetracycline efflux pump inhibitor in the presence of tetracycline using a reporter gene system where the tetA promoter directs transcription of a reporter gene (lacZ) while the tetA is under the control of the tet repressor encoded by the tetR gene is described. The method uses a cell having a reporter gene system where the tetA promoter directs transcription of a reporter gene (lacZ) and an active efflux system in which relatively modest levels of the efflux protein encoded by the tetA gene are produced in a constitutive manner, i.e., not under the control of the tet repressor encoded by the tetR gene. Test samples which are inhibitors of the TetA efflux protein will allow accumulation of tetracycline inside the cells at levels which will induce expression of the tetA-lacZ transcriptional fusion to give a positive signal.
Type:
Grant
Filed:
May 13, 1996
Date of Patent:
August 4, 1998
Assignee:
American Cyanamid Company
Inventors:
David Michael Rothstein, Gordon Gerald Guay
Abstract: Disclosed are cosmetic compositions for providing an artificial tan to skin which comprise dihydroxyacetone and an azole in a cosmetically or pharmaceutically acceptable carrier. Also disclosed is a method for providing an artificial tan to skin which comprises applying dihydroxyacetone and an azole to the skin.
Type:
Grant
Filed:
August 21, 1996
Date of Patent:
January 6, 1998
Assignee:
E-L Management Corp.
Inventors:
Saul Miklean, Konstantinos M. Lahanas, Nicolae Vrabie, Edward Pelle, Andrew J. Bevacqua
Abstract: Disclosed are solid silicone compositions comprising low molecular weight polyethylene solidifying agents and one or more non-volatile silicone fluids, along with a method for their preparation. The compositions are suitable for topical application to skin or hair, and are particularly useful in the preparation of novel skin treatment, hair treatment, lipstick and makeup products.
Abstract: The present invention relates to an isolated nucleic acid fragment comprising a nucleic acid sequence coding for an amphotropic retrovirus receptor. This receptor is referred to as GLVR2 and has approximately 62% homology with the GLVR1 gene encoding for Gibbon Ape Leukemia Virus (GALV). Differences for the type of retroviruses interacting with the receptors exist. The protein encoding by the GLVR2 gene, cells transformed or transfected by the gene and vectors containing the gene are also disclosed.
Type:
Grant
Filed:
January 4, 1996
Date of Patent:
May 27, 1997
Assignee:
American Cyanamid Company
Inventors:
Stephen V. Johann, Marja van Zeijl, Bryan M. O'Hara
Abstract: An isolated nucleic acid sequence is described having at least one siderophore biosynthetic gene from Bacillus subtilis encoding enzymes homologous to enterobactin enzymes EntA, EntB, EntC, EntE, and combinations thereof. Vectors containing the isolated nucleic acid sequence, host cells transformed wth the isolated nucleic acid sequence, and a method for identifying compounds having antibiotic activity against microorganisms with an enterobactin-type siderophore are also described.
Abstract: The present invention relates to an isolated nucleic acid fragment comprising a nucleic acid sequence coding for an amphotropic retrovirus receptor. This receptor is referred to as GLVR2 and has approximately 62% homology with the GLVR1 gene encoding Gibbon Ape Leukemia Virus (GALV) receptor. Differences in the type of retroviruses interacting with the receptors exist. The protein encoded by the GLVR2, cells transformed or transfected by the gene, and vectors containing the gene are also disclosed.
Type:
Grant
Filed:
April 16, 1993
Date of Patent:
August 27, 1996
Assignee:
American Cyanamid Company
Inventors:
Stephen V. Johann, Marja van Zeijl, Bryan M. O'Hara