Patents Represented by Attorney Kathleen R. S. Page

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  • Substituted 1-sulfonylbenzimidazoles
    Patent number: 4196125
    Abstract: Certain 1-sulfonyl-2,5(6)-substituted-benzimidazole compounds are useful as antiviral agents.
    Type: Grant
    Filed: March 16, 1978
    Date of Patent: April 1, 1980
    Assignee: Eli Lilly and Company
    Inventors: Charles J. Paget, James H. Wikel
  • Antibiotic A16886 and process for production thereof
    Patent number: 4191763
    Abstract: Antibiotic A16886I and antibiotic A16886II and their salts, having antibacterial and anthelmintic activity, prepared by fermentation of Streptomyces clavuligerus NRRL 3585.
    Type: Grant
    Filed: May 20, 1976
    Date of Patent: March 4, 1980
    Assignee: Eli Lilly and Company
    Inventors: Marvin Gorman, Calvin E. Higgens, Ramakrishnan Nagarajan
  • 5,6-Diaryl-1,2,4-triazines
    Patent number: 4190725
    Abstract: 5,6-Diaryl-1,2,4-triazines, topically-active anti-inflammatory agents, having the formula, ##STR1## wherein R is hydrogen or -(X).sub.n R.sub.1, in which X is either O or S, n is an integer which is either 0 or 1, and R.sub.1 is C.sub.1 -C.sub.8 alkyl, C.sub.7 -C.sub.8 aralkyl, C.sub.3 -C.sub.8 cycloalkyl, or C.sub.4 -C.sub.8 (cycloalkyl)alkyl; and R.sub.2 and R.sub.3 independently are C.sub.1 -C.sub.3 alkoxy or di(C.sub.1 -C.sub.3 alkyl)amino; with the proviso that when R.sub.2 and R.sub.3 both are methoxy, R cannot be H or methylthio; and the pharmaceutically-acceptable acid addition salts of basic members thereof.
    Type: Grant
    Filed: October 18, 1978
    Date of Patent: February 26, 1980
    Assignee: Eli Lilly and Company
    Inventor: William B. Lacefield
  • Rodenticidal N-alkyldiphenylamines
    Patent number: 4187318
    Abstract: A series of new diphenylamines have small alkyl substituents on the amino nitrogen. One phenyl ring bears dinitro-trifluoromethyl substitution, and the other is preferably substituted with halogen or pseudo-halogen groups. The new diphenylamines are useful as rodenticides.
    Type: Grant
    Filed: December 12, 1977
    Date of Patent: February 5, 1980
    Assignee: Eli Lilly and Company
    Inventor: Barry A. Dreikorn
  • Dinitroaniline purification with inorganic acid halides
    Patent number: 4185035
    Abstract: The present invention is directed to a process for reducing the concentration of nitrosamines in dinitroanilines, which comprises treating a nitrosamine-containing dinitroaniline with PCl.sub.3, PCl.sub.5, PBr.sub.3, POCl.sub.3, SCl.sub.2, SOCl.sub.2, SO.sub.2 Cl.sub.2, SOBr.sub.2, or TiCl.sub.4.
    Type: Grant
    Filed: February 17, 1978
    Date of Patent: January 22, 1980
    Assignee: Eli Lilly and Company
    Inventors: Richard F. Eizember, Kathleen R. Vogler
  • Alkylidenylmethyl-substituted 1-sulfonylbenzimidazoles
    Patent number: 4174454
    Abstract: Certain alkylidenylmethyl-substituted-1-sulfonylbenzimidazole compounds are useful as antiviral agents.
    Type: Grant
    Filed: March 3, 1978
    Date of Patent: November 13, 1979
    Assignee: Eli Lilly and Company
    Inventors: Charles J. Paget, James W. Chamberlin, James H. Wikel
  • 7-(5-Amino-5-carboxyvaler-amido)-3-(carbamoyloxymethyl)-7-methoxy-3-cep hem-4-carboxylic acid
    Patent number: 4173702
    Abstract: Antibiotic A16886I and antibiotic A16886II and their salts, having antibacterial and anthelmintic activity, prepared by fermentation of Streptomyces clavuligerus NRRL 3585.
    Type: Grant
    Filed: August 10, 1970
    Date of Patent: November 6, 1979
    Assignee: Eli Lilly and Company
    Inventors: Marvin Gorman, Calvin E. Higgens, Ramakrishnan Nagarajan
  • 1-Benzoyl-3-(alkoxy- or alkylthiopyridinyl)ureas
    Patent number: 4173639
    Abstract: The present invention is directed to 1-benzoyl-3-(alkoxy- or alkylthiopyridinyl)urea compounds useful as insecticides.
    Type: Grant
    Filed: August 31, 1978
    Date of Patent: November 6, 1979
    Assignee: Eli Lilly and Company
    Inventor: Robert G. Suhr
  • Thieno-benzodiazepines
    Patent number: 4172831
    Abstract: Thieno[1,5]benzodiazepines having useful CNS activity containing the novel tricyclic ring system: ##STR1## the 10-position being substituted by an amino, preferably a piperazino, group.
    Type: Grant
    Filed: April 13, 1977
    Date of Patent: October 30, 1979
    Assignee: Lilly Industries Limited
    Inventors: Jiban K. Chakrabarti, David E. Tupper
  • Dinitroanilines for control of soil-borne phytopathogens
    Patent number: 4156722
    Abstract: A class of 2,6-dinitroanilines having a broad range of substituent groups on the anilino nitrogen and in the 3- and 4-positions of the phenyl ring are used for the protection of plants against soil-borne phytopathogens of the genus Phytophthora.
    Type: Grant
    Filed: October 13, 1977
    Date of Patent: May 29, 1979
    Assignee: Eli Lilly and Company
    Inventor: James D. Froyd
  • Cyclopentone propanoic acid compounds
    Patent number: 4151199
    Abstract: Propanoic acid derivatives of the formula: ##STR1## where R.sup.1 is a C.sub.1-8 alkyl group optionally substituted by hydroxyl or --COOH and R.sup.2 is hydrogen or a protecting group, are useful as anti-thrombotic agents.
    Type: Grant
    Filed: December 4, 1975
    Date of Patent: April 24, 1979
    Assignee: Lilly Industries Limited
    Inventors: William Dawson, Michael J. Foulis, Norman J. A. Gutteridge, Colin W. Smith
  • Antiviral thiazolinyl benzimidazoles
    Patent number: 4150028
    Abstract: Certain thiazolinyl or thiazinyl ketobenzimidazole compounds and derivatives thereof are useful as antiviral agents.
    Type: Grant
    Filed: February 16, 1977
    Date of Patent: April 17, 1979
    Assignee: Eli Lilly and Company
    Inventors: Charles J. Paget, James W. Chamberlin, James H. Wikel
  • 3-Nitropyrazole derivatives
    Patent number: 4145554
    Abstract: Novel 1,4-disubstituted-3-nitropyrazoles having antimicrobial, parasiticidal, and herbicidal activity are prepared by a reaction sequence of which the individual steps are conventional. The new 3-nitropyrazoles are characterized by a 1-substituent and a usually carbonyl-containing 4-substituent. The novel 3(5)-nitro-4-pyrazolecarbonitrile is obtained as an intermediate in the preparation of the biologically-active compounds. Preferred compounds are 1-alkyl or -alkenyl-4-pyrazolecarboxamides and carbonitriles. The new compounds are particularly useful for the control of bacterial animal diseases.
    Type: Grant
    Filed: October 13, 1977
    Date of Patent: March 20, 1979
    Assignee: Eli Lilly and Company
    Inventors: Reuben G. Jones, Norman H. Terando
  • 3-Carbamyloxymethyl-cephalosporins
    Patent number: 4145538
    Abstract: The present invention is directed to 7-amino-3-carbamoyloxymethyl-3-cephem-4-carboxylic acid: ##STR1## and to precursors and derivatives. The compound, its precursors, and its derivatives exhibit antibacterial activity, which, in the instance of certain of the derivatives, is of an enhanced degree.
    Type: Grant
    Filed: September 7, 1977
    Date of Patent: March 20, 1979
    Assignee: Eli Lilly and Company
    Inventor: Ramakrishnan Nagarajan
  • (Phenoxyphenyl) alkyl acetates, propionates, and carbamates
    Patent number: 4145557
    Abstract: Novel 3-phenoxyphenylalkyl amines and the amides, alcohols, tetrazoles, and carbamates related thereto as well as novel intermediates useful in the preparation of such compounds. The compounds of this invention are useful as anti-inflammatory, analgesic, and antipyretic agents.
    Type: Grant
    Filed: February 14, 1977
    Date of Patent: March 20, 1979
    Assignee: Eli Lilly and Company
    Inventor: Winston S. Marshall
  • Cephalosporin displacement reaction
    Patent number: 4144391
    Abstract: The present invention is directed to a process for the displacement of the acetoxy group of a cephalosporanic acid by a sulfur nucleophile, in an organic solvent and under essentially anhydrous conditions.
    Type: Grant
    Filed: December 27, 1977
    Date of Patent: March 13, 1979
    Assignee: Eli Lilly and Company
    Inventor: Lowell D. Hatfield
  • N-pyridyl-N-phenylamines as rodenticides
    Patent number: 4140778
    Abstract: Certain substituted N-pyridyl-N-phenylamines as rodenticides.
    Type: Grant
    Filed: July 18, 1977
    Date of Patent: February 20, 1979
    Assignee: Eli Lilly and Company
    Inventor: Barry A. Dreikorn
  • 1-Acyl-4-substituted phenyl thiosemicarbazides
    Patent number: 4134914
    Abstract: A novel process for the preparation of s-triazolo[3,4-b]benzothiazole compounds comprises reacting a molar equivalent of base in an amide solvent at a temperature from 60.degree. C. to 200.degree. C. with (a) a 1-acyl-4-(o-halophenyl)thiosemicarbazide compound or (b) a 4-(o-halophenyl)-1,2,4-triazole-3-thiol compound and recovering the product. The s-triazolo[3,4-b]benzothiazole compounds are useful for the control of plant pathogens.
    Type: Grant
    Filed: December 22, 1977
    Date of Patent: January 16, 1979
    Assignee: Eli Lilly and Company
    Inventors: Charles J. Paget, James H. Wikel
  • Benzophenone derivatives
    Patent number: 4134993
    Abstract: Novel benzophenone derivatives having anti-allergy activity, and pharmaceutical formulations and methods of treatment utilizing benzophenone derivatives.
    Type: Grant
    Filed: October 11, 1977
    Date of Patent: January 16, 1979
    Assignee: Eli Lilly and Company
    Inventors: Delme Evans, John C. Saunders, William R. N. Williamson
  • Antibiotic A16886II
    Patent number: 4132790
    Abstract: Antibiotic A16886I and antibiotic A16886II and their salts, having antibacterial and anthelmintic activity, prepared by fermentation of Streptomyces clavuligerus NRRL 3585.
    Type: Grant
    Filed: May 20, 1976
    Date of Patent: January 2, 1979
    Assignee: Eli Lilly and Company
    Inventors: Marvin Gorman, Calvin E. Higgens, Ramakrishnan Nagarajan