Abstract: The present invention provides 3-hydroxyphenyl-2,4-pyrimidinediamine compounds of formula I, as well as related compositions and methods for treating a variety of autoimmune diseases.

Abstract: A passenger seat assembly for a vehicle, particularly an aircraft, which is adapted to provide self-contained, individual seating and sleeping accommodation for a passenger, said seating assembly includes a supporting structure (42) for supporting said assembly off the floor of a vehicle; one or more movable, passenger-bearing, structural components (71,72); and means for connecting said movable, structural components to said structure such that said components can be selectively moved between a seat configuration, in which a plurality of passenger-bearing surfaces on said one or more structural, movable components (71,71) or said supporting structure form a seat for the passenger, and a bed configuration, in which a plurality of said bearing surfaces (47,48,67,74,76) are disposed substantially coplanarly and substantially contiguously to form a bed for the passenger; characterized in that at least one of said movable components (72) is double-sided, comprising first and second opposite sides, one of said sid

Abstract: Embodiments of the disclosed technology comprise techniques that can be used to generate scan chain test patterns and improve scan chain failure diagnosis resolution. For example, certain embodiments can be used to generate high quality chain diagnosis test patterns that are able to isolate a scan chain defect to a single scan cell. At least some embodiments can be used to locate faults over multiple capture cycles in the scan chain.

Abstract: A concrete floating dock can be formed using a form that has an inner and an outer form. Concrete sections can be cast such that they include a deck portion and two longitudinally extending side walls that extend downwardly from the deck portion. The concrete sections can be removed from the form and coupled together to form a concrete floating dock. One or more buoyancy elements can be positioned in the cavities of the fully cured concrete sections before or after the concrete sections are coupled to each other.

Abstract: A digital media codec adaptively re-arranges a coefficient scan order of transform coefficients in accordance with the local statistics of the digital media, so that the coefficients can be encoded more efficiently using entropy encoding. The adaptive scan ordering is applied causally at encoding and decoding to avoid explicitly signaling the scan order to the decoder in the compressed digital media stream. For computational efficiency, the adaptive scan order re-arranges the scan order by applying a conditional exchange operation on adjacently ordered coefficient locations via a single traversal of the scan order per update of the statistical analysis.

Abstract: Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time.

Abstract: A video encoder uses previously calculated motion information for inter frame coding to achieve faster computation speed for video compression. In a multi bit rate application, motion information produced by motion estimation for inter frame coding of a compressed video bit stream at one bit rate is passed on to a subsequent encoding of the video at a lower bit rate. The video encoder chooses to use the previously calculated motion information for inter frame coding at the lower bit rate if the video resolution is unchanged. A multi core motion information pre-calculation produces motion information prior to encoding by dividing motion estimation of each inter frame to separate CPU cores.

Abstract: The present application allows wake-up and unlock operations to occur using a single event, such as a single keystroke. Additionally, a check is made to ensure that activation was caused by human touch, not an object. In one embodiment, an area of a mobile device is designated as a wake-up area, which is separate from the touch screen. A user can touch the wake-up area to both activate the mobile device from a sleep mode and unlock the mobile device. In another embodiment, the wake-up area can be integrated into the touch screen, so that there is not an appearance of a separate button. Fingerprint checking and/or proximity sensors can also be integrated into the mobile device.

Abstract: An electrical circuit comprising a plurality of cells can be simulated to produce simulation results by sorting cells between active status cells and inactive status cells and reducing the processing of simulation results from inactive cells to thereby save simulation time.

Abstract: An apparatus is provided for collecting amniotic fluid from the uterus. In order to collect the amniotic fluid from the uterus through the external orifice of the cervix of a pregnant woman, an amniotic fluid collecting unit is adapted to bring a mouth, which is foldably formed at the upper end of an amniotic fluid collecting bag, into close contact with an end of the external orifice of the cervix. Thereby, the apparatus not only significantly decreases the risk occurring when a needle is directly inserted into the uterus in order to carry out the amniocentesis (amniotic fluid testing), but also eliminates pain and anxiety caused by the direct insertion of the needle.

Abstract: An infrared light emitting diode circuit and related methods are disclosed. Exemplary features of embodiments comprise circuitry for controlling the voltage delivered to infrared light emitting diodes and for reducing the power consumption of the circuitry in the absence of audio signals to be transmitted.

Abstract: A golf club comprises a shaft, a club head, and a connection assembly that allows the shaft to be easily disconnected from the club head. In particular embodiments, a sleeve including a top portion, a middle portion connected to the top portion is described. The middle portion includes a thin wall thickness. A bottom portion is connected to the middle portion including a plurality of engaging surfaces. A central longitudinal axis and an offset angle offset from the central longitudinal axis is described. The offset angle allows a maximum loft change of about 0.5 degrees to about 4.0 degrees. The total weight of the sleeve is less than 9 g.

Abstract: The invention encompasses compounds having formula I and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, are therapeutically useful.

Abstract: Methods are disclosed for manufacturing piezoelectric devices. An exemplary method comprises the step of bonding a lid wafer, a piezoelectric frame wafer (having a vibrating piece and a outer frame surrounding the vibrating piece), and a base wafer (having at least one wiring through-hole) together. A surface of a unit (typically ball-shaped) of eutectic metal is cleaned and then arranged on the through-hole. The unit of eutectic metal is then melted in a vacuum or inert gas environment to allow the eutectic metal to enter the through-hole.

Abstract: The present disclosure pertains to composite articles, and in particular a composite face plate for a golf club-head, and methods for making the same. In certain embodiments, a composite face plate for a club-head is formed with a cross-sectional profile having a varying thickness. The face plate comprises a lay-up of multiple, composite prepreg plies. At least a portion of the plies comprise a plurality of elongated prepreg strips arranged in a predetermined criss-cross pattern in the lay-up. The prepreg strips create one or more areas of increased thickness where the strips overlap each other, thereby creating a desired profile for the plate. Metallic or polymer covers or cover layers can be used to define a striking surface.

Abstract: A new and distinct Echinacea plant named ‘Mama Mia’ characterized by large inflorescences, bicolor ray florets that change color with maturity giving multiple colors on one plant—from orange to red orange to red purple, a medium large habit with excellent branching, numerous, strong stems, and excellent vigor.

Abstract: A new and distinct Heuchera plant characterized by medium red brown leaves year round, very free flowering on medium to short flower stalks, creamy yellow flowers on red peduncles, well branched, mounding habit, and excellent vigor.

Abstract: A new and distinct Geum plant named ‘Fire Storm’ characterized by orange flower color, large, double flowers, a compact, upright habit, long bloom time, and excellent vigor.

Abstract: A golf club head has a body having a top, a sole, a toe end, a heel end, and a forward wall. The forward wall defines a front opening about which a face support is disposed. The face support receives a face plate, thereby enclosing the front opening of the body. The face support includes portions proximate to the top, the toe end, and the heel end, each portion having a peripheral member extending rearward from the forward wall and a rear member extending inward from the peripheral member, with respect to the front opening. The face support can be combined with a preferred face construction and weight elements to optimize club head performance to help a golfer achieve greater distance and control.